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    MARKERS ASSOCIATED WITH WNT INHIBITORS
    12.
    发明申请
    MARKERS ASSOCIATED WITH WNT INHIBITORS 有权
    与WNT抑制剂相关的标记

    公开(公告)号：US20160024587A1

    公开(公告)日：2016-01-28

    申请号：US14774212

    申请日：2014-03-10

    申请人： Jianwei CHE ,  Jennifer HARRIS ,  Hsin-I HSIEH ,  Jie LI ,  Jun LIU ,  Nicholas NG

    发明人： Jianwei Che ,  Jennifer Harris ,  Hsin-I Hsieh ,  Jie Li ,  Jun Liu ,  Nicholas Ng

    IPC分类号： C12Q1/68 ,  A61K31/497

    摘要： The invention provides methods of monitoring differential gene expression of biomarkers to determine patient sensitivity to Wnt inhibitor, methods of determining the sensitivity of a cell to an Wnt inhibitor by measuring biomarkers, methods of screening for candidate Wnt inhibitor, Wnt inhibitor for use in head and neck squamous cell carcinoma.

    摘要翻译： 本发明提供监测生物标志物的差异基因表达以确定患者对Wnt抑制剂的敏感性的方法，通过测量生物标志物来测定细胞对Wnt抑制剂的敏感性的方法，筛选候选Wnt抑制剂的方法，用于头部的Wnt抑制剂和 颈鳞状细胞癌。

    Electrical all-dimensional numerical control injection molding machine
    13.
    发明授权
    Electrical all-dimensional numerical control injection molding machine 有权
    电动全尺寸数控注塑机

    公开(公告)号：US09079348B2

    公开(公告)日：2015-07-14

    申请号：US14234408

    申请日：2012-06-14

    申请人： Jun Liu

    发明人： Jun Liu

    IPC分类号： B29C45/33 ,  B29C45/80 ,  B29C45/17 ,  B29C45/66 ,  B29C45/72

    CPC分类号： B29C45/80 ,  B29C45/17 ,  B29C45/33 ,  B29C45/332 ,  B29C45/66 ,  B29C45/72 ,  B29C2045/1792

    摘要： An electric all-dimensional numerical control injection molding machine is applicable to production of injection products with high precision and complex three-dimensional shapes. The machine comprises a machine base, a main board, four sets of electric mould guiding devices, a cross-shaped chute mould assembly, and an injection device assembly. The electric mould guiding devices are mounted on a front face of the machine. A slider mould is disposed in a chute of a cross-shaped mould base, is connected to a shaft of an electric driver, and implements mould opening and closing functions by means of linear movement of the shaft of the electric driver. An injection system of the machine is used for injecting plasticized, fused, and homogenized plastic materials into a mould cavity of the mould.

    摘要翻译： 电动全尺寸数控注塑机适用于高精度，复杂三维形状的注塑产品生产。 该机器包括机座，主板，四组电动模具引导装置，十字形滑道模组件和注射装置组件。 电动模具引导装置安装在机器的前表面上。 滑块模具设置在十字形模座的斜槽中，连接到电动驱动器的轴上，并且通过电动驱动器的轴的线性运动来实现模具打开和关闭功能。 该机器的注射系统用于将塑化，熔化和均质的塑料材料注入模具的模腔中。

    Generating a regulated signal from another regulated signal
    14.
    发明授权
    Generating a regulated signal from another regulated signal 有权
    从另一个调节信号产生调节信号

    公开(公告)号：US09075423B2

    公开(公告)日：2015-07-07

    申请号：US12859478

    申请日：2010-08-19

    申请人： Liang Zhu ,  Jun Liu ,  Hai Bo Zhang

    发明人： Liang Zhu ,  Jun Liu ,  Hai Bo Zhang

    IPC分类号： G05F1/577 ,  G05F1/575 ,  H02M3/145

    CPC分类号： G05F1/575

    摘要： An embodiment of a method includes generating a regulated output signal from a regulated intermediate signal in response to a reference signal and the regulated output signal, and generating the regulated intermediate signal from an input signal in response to the regulated output signal and the regulated intermediate signal. By generating one regulated signal (e.g., a regulated output voltage) from another regulated signal (e.g., a regulated intermediate voltage), the magnitude of the ripple component of the one regulated signal may be reduced. Furthermore, by generating the regulated intermediate signal in response to the regulated output signal, the efficiency of the regulation may be increased.

    摘要翻译： 一种方法的实施例包括响应于参考信号和调节的输出信号从调节的中间信号产生调节的输出信号，以及响应于调节的输出信号和调节的中间信号从输入信号产生调节的中间信号 。 通过从另一调节信号（例如，调节中间电压）产生一个调节信号（例如，调节输出电压），可以减小一个调节信号的纹波分量的幅度。 此外，通过响应于调节的输出信号产生调节的中间信号，可以提高调节的效率。