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37 条记录 (耗时 0.023 秒)

    Percutaneous myocardial revascularization
    11.
    发明授权
    Percutaneous myocardial revascularization 失效
    经皮心肌血运重建

    公开(公告)号：US07832406B2

    公开(公告)日：2010-11-16

    申请号：US11191056

    申请日：2005-07-28

    申请人： Louis Ellis ,  Daniel M. Lafontaine ,  Roger N. Hastings ,  Lauri DeVore

    发明人： Louis Ellis ,  Daniel M. Lafontaine ,  Roger N. Hastings ,  Lauri DeVore

    IPC分类号： A61B19/00 ,  A61B18/18

    CPC分类号： A61B17/3207 ,  A61B18/1492 ,  A61B90/39 ,  A61B2017/00247 ,  A61B2017/22077 ,  A61B2017/3488 ,  A61B2018/00273 ,  A61B2018/00291 ,  A61B2018/00392 ,  A61B2018/144 ,  A61B2090/395 ,  A61M2210/125

    摘要： Devices and methods for creating a series of percutaneous myocardial revascularization (PMR) channels in the heart. One method includes forming a pattern of channels in the myocardium leading from healthy tissue to hibernating tissue. Suitable channel patterns include lines and arrays. One method includes anchoring a radiopaque marker to a position in the ventricle wall, then using fluoroscopy repeatedly to guide positioning of a cutting tip in the formation of multiple channels. Another method uses radiopaque material injected into each channel formed, as a marker. Yet another method utilizes an anchorable, rotatable cutting probe for channel formation about an anchor member, where the cutting probe can vary in radial distance from the anchor. Still another method utilizes a multiple wire radio frequency burning probe, for formation of multiple channels simultaneously. Still another method utilizes liquid nitrogen to cause localized tissue death.

    摘要翻译： 在心脏中创建一系列经皮心肌血运重建（PMR）通道的装置和方法。 一种方法包括在从健康组织导向冬眠组织的心肌中形成通道图案。 合适的渠道模式包括线和阵列。 一种方法包括将不透射线标记物固定在心室壁中的位置，然后重复使用荧光透视来引导切割尖端在形成多个通道中的定位。 另一种方法使用注射到形成的每个通道中的不透射线材料作为标记。 另一种方法利用可锚定的，可旋转的切割探针，用于围绕锚定构件的通道形成，其中切割探针可以与锚固件的径向距离变化。 另一种方法是利用多线射频燃烧探头，同时形成多个通道。 另一种方法利用液氮引起局部组织死亡。

    Transmyocardial revascularization catheter and method
    14.
    发明授权
    Transmyocardial revascularization catheter and method 失效
    经心肌血运重建导管及方法

    公开(公告)号：US5968059A

    公开(公告)日：1999-10-19

    申请号：US812425

    申请日：1997-03-06

    申请人： Louis Ellis ,  Gary L. Hendrickson

    发明人： Louis Ellis ,  Gary L. Hendrickson

    IPC分类号： A61B17/00 ,  A61B17/16 ,  A61B17/22 ,  A61B17/32

    CPC分类号： A61B17/32002 ,  A61B17/320758 ,  A61B2017/00247 ,  A61B2017/003 ,  A61B2017/22077 ,  A61B2018/00208 ,  A61B2018/00392 ,  A61B2018/1861

    摘要： A transmyocardial revascularization catheter which includes an elongate drive shaft having a proximal end, a distal end and a longitudinal axis. The TMR catheter also includes a cutting tip disposed at the distal end of the shaft. The tip has a distally disposed cutting edge and a longitudinally extending lumen therethrough. A motor is coupled to the drive shaft for rotation of the cutting tip. The shaft defines a longitudinally extending lumen in fluid communication with the tip lumen.

    摘要翻译： 一种经心肌血运重建导管，其包括具有近端，远端和纵向轴线的细长驱动轴。 TMR导管还包括设置在轴的远端处的切割尖端。 尖端具有远处设置的切割刃和穿过其中的纵向延伸的内腔。 电动机联接到驱动轴以用于切割尖端的旋转。 轴限定与尖端腔流体连通的纵向延伸的内腔。

    Intravascular filter retrieval device having an actuatable dilator tip
    15.
    发明授权
    Intravascular filter retrieval device having an actuatable dilator tip 失效
    具有可致动扩张器尖端的血管内滤器取出装置

    公开(公告)号：US08034074B2

    公开(公告)日：2011-10-11

    申请号：US11616612

    申请日：2006-12-27

    申请人： Joseph Garner ,  Matthew L. Young ,  Andrew Forsberg ,  Louis Ellis ,  Gary Hendrickson

    发明人： Joseph Garner ,  Matthew L. Young ,  Andrew Forsberg ,  Louis Ellis ,  Gary Hendrickson

    IPC分类号： A61M29/00

    CPC分类号： A61F2/013 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/005 ,  A61F2230/0067

    摘要： A filter retrieval device having an actuatable dilator tip for retrieval of an intravascular filter from a body lumen is disclosed. An outer shaft coupled to a distal sheath is advanced along a filter wire to desired point within the vasculature. An intravascular filter such as a distal protection filter can be advanced along the filter wire to a point distal a lesion to collect debris dislodged during a medical procedure. Disposable in part within the distal sheath is an actuatable dilator tip adapted to retrieve the filter at least in part within the distal sheath. Actuation of the dilator tip may be accomplished by any number of means, including a resilient member such as a spring coil, or by a reduced inner diameter portion disposed on the distal sheath adapted to engage a plurality of recessed surfaces disposed on the dilator tip.

    摘要翻译： 公开了一种具有用于从体腔取回血管内过滤器的可致动扩张器尖端的过滤器取出装置。 联接到远侧护套的外轴沿着过滤丝前进到脉管系统内的期望点。 血管内过滤器，例如远侧保护过滤器可以沿着过滤器丝线前进到损伤部分的远端以收集在医疗过程中移动的碎屑。 部分地在远端鞘内的一次性部分是可致动的扩张器末端，其适于至少部分地在远侧鞘内取回过滤器。 扩张器尖端的致动可以通过任何数量的装置来实现，包括诸如弹簧线圈的弹性构件，或者通过设置在远侧护套上的减小的内径部分，适于接合设置在扩张器尖端上的多个凹陷表面。

    Biocompatible medical devices
    16.
    发明申请
    Biocompatible medical devices 有权
    生物相容性医疗器械

    公开(公告)号：US20070197980A1

    公开(公告)日：2007-08-23

    申请号：US11451634

    申请日：2006-06-12

    申请人： James Barry ,  Maria Palasis ,  Louis Ellis ,  Timothy Mickley ,  Brian Berg

    发明人： James Barry ,  Maria Palasis ,  Louis Ellis ,  Timothy Mickley ,  Brian Berg

    IPC分类号： A61M25/00

    CPC分类号： A61L29/085 ,  A61L29/103 ,  A61L29/106 ,  A61L31/10

    摘要： A modified medical device for delivery of a pharmaceutically active material is described. The present inventors have found that many conventional medical devices contain a metallic or polymeric component that comes into contact with a pharmaceutically active material during use, and that the contact substantially reduce the pharmaceutical effectiveness of the pharmaceutically active material. The invention described herein concerns various modifications to the metallic or polymeric component that are effective to diminish such a substantial reduction in pharmaceutical effectiveness.

    摘要翻译： 描述了用于递送药物活性物质的改进的医疗装置。 本发明人已经发现许多常规医疗器械含有在使用过程中与药物活性物质接触的金属或聚合物组分，并且接触显着降低了药物活性物质的药物有效性。 本文描述的发明涉及对金属或聚合物组分的各种修饰，其有效地减少药物有效性的这种显着降低。

    Intravascular filter retrieval device having an actuatable dilator tip
    17.
    发明授权
    Intravascular filter retrieval device having an actuatable dilator tip 失效
    具有可致动扩张器尖端的血管内滤器取出装置

    公开(公告)号：US07226464B2

    公开(公告)日：2007-06-05

    申请号：US10083810

    申请日：2002-02-27

    申请人： Joseph Garner ,  Matthew L. Young ,  Andrew Forsberg ,  Louis Ellis ,  Gary Hendrickson

    发明人： Joseph Garner ,  Matthew L. Young ,  Andrew Forsberg ,  Louis Ellis ,  Gary Hendrickson

    IPC分类号： A61M29/00

    CPC分类号： A61F2/013 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/005 ,  A61F2230/0067

    摘要： A filter retrieval device having an actuatable dilator tip for retrieval of an intravascular filter from a body lumen is disclosed. An outer shaft coupled to a distal sheath is advanced along a filter wire to desired point within the vasculature. An intravascular filter such as a distal protection filter can be advanced along the filter wire to a point distal a lesion to collect debris dislodged during a medical procedure. Disposable in part within the distal sheath is an actuatable dilator tip adapted to retrieve the filter at least in part within the distal sheath. Actuation of the dilator tip may be accomplished by any number of means, including a resilient member such as a spring coil, or by a reduced inner diameter portion disposed on the distal sheath adapted to engage a plurality of recessed surfaces disposed on the dilator tip.

    摘要翻译： 公开了一种具有用于从体腔取回血管内过滤器的可致动扩张器尖端的过滤器取出装置。 联接到远侧护套的外轴沿着过滤丝前进到脉管系统内的期望点。 血管内过滤器，例如远侧保护过滤器可以沿着过滤器丝线前进到损伤部分的远端以收集在医疗过程中移动的碎屑。 部分地在远端鞘内的一次性部分是可致动的扩张器末端，其适于至少部分地在远侧鞘内取回过滤器。 扩张器尖端的致动可以通过任何数量的装置来实现，包括诸如弹簧线圈的弹性构件，或者通过设置在远侧护套上的减小的内径部分，适于接合设置在扩张器尖端上的多个凹陷表面。

    Catheter system for the delivery of a low volume bolus
    18.
    发明授权
    Catheter system for the delivery of a low volume bolus 有权
    用于输送低体积推注的导管系统

    公开(公告)号：US06764461B2

    公开(公告)日：2004-07-20

    申请号：US09138131

    申请日：1998-08-21

    申请人： Timothy J. Mickley ,  Thomas R. Hektner ,  Louis Ellis ,  Gary L. Hendrickson

    发明人： Timothy J. Mickley ,  Thomas R. Hektner ,  Louis Ellis ,  Gary L. Hendrickson

    IPC分类号： A61F1320

    CPC分类号： A61M25/104 ,  A61M5/00 ,  A61M29/02 ,  A61M2025/0057 ,  A61M2025/1013 ,  A61M2025/105 ,  A61M2025/1086 ,  A61M2025/1093

    摘要： A catheter system includes a catheter having a proximal end, a distal end, and a lumen extending therein. An administering portion is disposed at the distal end of the catheter and is configured to administer a bolus of liquid in response to positive pressure in a distal portion of the lumen. The catheter system of the present invention has a dead space of less 0.32 cc and preferably less than 0.15 cc in which residual therapeutic agents remain after delivery. The present invention also includes a method of administering a liquid to a treatment site. The distal end of the catheter is transluminally positioned proximate the treatment site. The catheter is charged by placing a bolus of the liquid in the lumen A positive pressure is created to drive the bolus to the administering tip to express the bolus from the distal end of the catheter.

    摘要翻译： 导管系统包括具有近端，远端和在其中延伸的内腔的导管。 给药部分设置在导管的远端处，并且构造成响应于内腔的远端部分中的正压而施用大量液体。 本发明的导管系统具有小于0.32cc，优选小于0.15cc的死空间，其中残留的治疗剂在分娩后残留。 本发明还包括向处理部位施用液体的方法。 导管的远端位于治疗部位附近。 导管通过将大量液体放置在内腔中来进行充电。产生正压力以将推注驱动到施用尖端以从导管的远端表达推注。

    Biocompatible medical devices
    19.
    发明授权
    Biocompatible medical devices 失效
    生物相容性医疗器械

    公开(公告)号：US06638259B1

    公开(公告)日：2003-10-28

    申请号：US09429178

    申请日：1999-10-28

    申请人： Maria Palasis ,  Louis Ellis ,  Timothy Mickley

    发明人： Maria Palasis ,  Louis Ellis ,  Timothy Mickley

    IPC分类号： A61M2500

    CPC分类号： A61L29/085 ,  A61L2/18 ,  A61L29/08 ,  A61L29/103 ,  A61L29/106 ,  A61L29/14 ,  A61L31/10 ,  A61L33/0076 ,  C23C22/50

    摘要： A modified medical device for delivery of a pharmaceutically active material is described. The present inventors have found that many conventional medical devices contain a metallic component that comes into contact with a pharmaceutically active material during use, and that the contact substantially reduce the pharmaceutical effectiveness of the pharmaceutically active material. The invention described herein concerns numerous modifications to the metallic component that are effective to prevent such a substantial reduction in pharmaceutical effectiveness.

    摘要翻译： 描述了用于递送药物活性物质的改进的医疗装置。 本发明人已经发现许多常规医疗器械含有在使用期间与药物活性物质接触的金属成分，并且接触显着降低了药物活性物质的药物有效性。 本文描述的发明涉及对金属组分的许多修改，其有效地防止药物效力的显着降低。

    Shaft movement control apparatus and method
    20.
    发明授权
    Shaft movement control apparatus and method 失效
    轴运动控制装置及方法

    公开(公告)号：US5570701A

    公开(公告)日：1996-11-05

    申请号：US141280

    申请日：1993-10-22

    申请人： Louis Ellis ,  Roger N. Hastings

    发明人： Louis Ellis ,  Roger N. Hastings

    IPC分类号： A61M25/01 ,  A61M25/088 ,  A61B5/00

    CPC分类号： A61M25/0127 ,  A61M25/0169 ,  A61M25/09041 ,  A61M2025/09116

    摘要： The present invention is a device and method for controlling longitudinal movement of a tube relative to a shaft slidably disposed within the tube, especially in the catheterization of a patient. An operative segment on the shaft cooperates with an ancillary tool to create a coupling force field between the shaft and the tool. The tube can then be moved over the shaft while the coupling force field operates through the tube to restrict the movement of the shaft. In preferred embodiment, the shaft is a guide wire and the tube is a catheter with a lumen for slidably receiving the guide wire, while the coupling force field is created magnetically. In one embodiment, the operative segment is borne on a short guide wire extension which is selectively securable to a standard guide wire. In another embodiment a pair of electrical coils are placed around the magnetically operative segment to couple therewith and provide signals indicative of the movement and position of the guide wire.

    摘要翻译： 本发明是一种用于控制管相对于可滑动地设置在管内的轴的纵向运动的装置和方法，特别是在患者的导管插入中。 轴上的操作段与辅助工具协作以在轴和工具之间产生联接力场。 然后，管可以在轴上移动，同时耦合力场通过管操作以限制轴的运动。 在优选实施例中，所述轴是导丝，并且所述管是具有用于可滑动地接收所述导丝的内腔的导管，而所述耦合力场是磁力产生的。 在一个实施例中，操作段承载在可选择性地固定到标准导丝的短导丝延伸部上。 在另一个实施例中，一对电线圈被放置在磁性操作段周围以与之耦合，并且提供指示导丝的移动和位置的信号。