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30 条记录 (耗时 0.03 秒)

    Disposable container for a centrifuge
    13.
    发明授权
    Disposable container for a centrifuge 失效
    离心机一次性容器

    公开(公告)号：US5006103A

    公开(公告)日：1991-04-09

    申请号：US463694

    申请日：1990-01-11

    申请人： David V. Bacehowski ,  Herbert M. Cullis ,  Armand R. Van Baelen

    发明人： David V. Bacehowski ,  Herbert M. Cullis ,  Armand R. Van Baelen

    IPC分类号： B04B1/00 ,  B04B5/04 ,  C07K16/06 ,  C07K16/30 ,  F04B9/02 ,  F04B43/10

    CPC分类号： F04B43/10 ,  B04B1/00 ,  B04B5/0428 ,  B04B5/0442 ,  C07K16/06 ,  C07K16/30 ,  F04B9/02 ,  B04B2005/045 ,  B04B2005/0464

    摘要： A blood component separating device comprises a centrifuge bowl adapted for rotation about its axis in a centrifuge. The bowl defines an outer circumferential wall plus an inner circumferential wall, spaced from the outer wall, to define a circumferential slot adapted for receiving blood components. Access tubing is adapted for communication with the slot. Preferably, an elongated, flexible, collapsible inner liner is provided in the slot. Individual access tubing also may communicate with an elongated container interior between the ends of the elongated, collapsible container. Furthermore, a portion of the slot may define the shape of an outwardly extending spiral, to provide an increasing gravitational field upon fluids therein as the fluid moves along the slot.

    摘要翻译： 血液成分分离装置包括适于在离心机中围绕其轴旋转的离心机碗。 碗限定外周壁加上与外壁间隔开的内周壁，以限定适于接收血液成分的圆周槽。 接入管适用于与槽连通。 优选地，在狭槽中设置细长的，柔性的可折叠内衬。 单独的进入管也可以与细长的可收缩容器的端部之间的细长的容器内部连通。 此外，槽的一部分可以限定向外延伸的螺旋的形状，以在流体沿着狭槽移动时为其中的流体提供增加的重力场。

    Adherent cell culture flask
    14.
    发明授权
    Adherent cell culture flask 失效
    贴壁细胞培养瓶

    公开(公告)号：US4939151A

    公开(公告)日：1990-07-03

    申请号：US382051

    申请日：1989-07-13

    申请人： David V. Bacehowski ,  Julian P. Breillatt, Jr. ,  William Kolanko ,  Sidney T. Smith

    发明人： David V. Bacehowski ,  Julian P. Breillatt, Jr. ,  William Kolanko ,  Sidney T. Smith

    IPC分类号： C12M1/00 ,  C12M1/24 ,  C12M3/00

    CPC分类号： C12M23/24 ,  C12M23/08 ,  C12M23/26 ,  C12M25/08

    摘要： An adherent cell culture flask is provided. The flask includes a body constructed from a first side wall and a second side wall, each side wall having an interior surface and an exterior surface. The first and second side walls are sealed together to define a chamber. The first side wall is constructed from flexible film and includes on its interior surface a charged surface for facilitating the attachment of cells thereto. The second side wall is constructed from flexible film and includes a non-smooth interior surface for preventing the first side wall interior surface from sticking to the second side wall interior surface.

    摘要翻译： 提供贴壁细胞培养瓶。 烧瓶包括由第一侧壁和第二侧壁构成的主体，每个侧壁具有内表面和外表面。 第一和第二侧壁被密封在一起以限定室。 第一侧壁由柔性膜构成并且在其内表面上包括带电表面以便于将细胞附着于其上。 第二侧壁由柔性膜构成，并且包括不平滑的内表面，用于防止第一侧壁内表面粘附到第二侧壁内表面。

    Method of manufacturing a blood bag for use in a test for neutrophil marrow reserves
    15.
    发明授权
    Method of manufacturing a blood bag for use in a test for neutrophil marrow reserves 失效
    制造用于中性粒细胞骨髓储备试验的血袋的方法

    公开(公告)号：US4152184A

    公开(公告)日：1979-05-01

    申请号：US769993

    申请日：1977-02-18

    申请人： David V. Bacehowski

    发明人： David V. Bacehowski

    IPC分类号： A61J1/00 ,  A61J1/05 ,  A61M1/02 ,  B29C27/00

    CPC分类号： A61M1/0218 ,  A61J1/10 ,  A61M1/0236 ,  Y10T156/1016 ,  Y10T29/49826

    摘要： A flexible, collapsible blood bag which defines an access port at one end thereof. The blood bag contains cellophane film of sufficient area to process blood or plasma placed in the bag, so that reinfusion of the blood to a normal donor, after an appropriate residence time in the bag, causes a transient increase in the neutrophil count of the donor's blood. The cellophane film in the bag is folded in an ordered manner, to define generally parallel flow channels having ends positioned adjacent the access port. A screen member may be positioned between the cellophane film and the access port to prevent blocking thereof by the cellophane film. Also, the cellophane film may define a large plurality of raised surface portions, relative to the normal plane of the film, to facilitate the spacing of adjacent, folded layers of the film from each other. This facilitates the definition of the flow channels for blood distribution throughout the cellophane film.

    摘要翻译： 一种灵活的，可折叠的血袋，其在其一端限定出入口。 血袋中含有足够面积的玻璃纸，用于处理放置在袋子中的血液或血浆，以便在适当的袋子停留时间之后，将血液再次输送到正常供体，导致捐赠者的嗜中性粒细胞计数暂时增加 血液。 袋中的玻璃纸膜以有序的方式折叠，以限定具有邻近进入端口定位的端部的大致平行的流动通道。 屏幕构件可以位于玻璃纸膜和进入端口之间，以防止玻璃纸膜阻挡玻璃纸。 此外，玻璃纸膜可以相对于膜的法线平面限定大量的多个凸起表面部分，以便于膜的相邻折叠层彼此的间隔。 这有助于定义整个玻璃纸上血液分布的流动通道。

    Combination disposable plastic blood receiving container and blood component centrifuge
    18.
    发明授权
    Combination disposable plastic blood receiving container and blood component centrifuge 失效
    组合一次性塑料血液接收容器和血液成分离心机

    公开(公告)号：US5217426A

    公开(公告)日：1993-06-08

    申请号：US744947

    申请日：1991-08-14

    申请人： David V. Bacehowski ,  Herbert M. Cullis ,  Armand R. VanBaelen

    发明人： David V. Bacehowski ,  Herbert M. Cullis ,  Armand R. VanBaelen

    IPC分类号： B04B1/00 ,  B04B5/04 ,  C07K16/06 ,  C07K16/30 ,  F04B9/02 ,  F04B43/10

    CPC分类号： C07K16/06 ,  B04B1/00 ,  B04B5/0428 ,  B04B5/0442 ,  C07K16/30 ,  F04B43/10 ,  F04B9/02 ,  B04B2005/045 ,  B04B2005/0464

    摘要： A blood component separating device comprises a centrifuge bowl adapted for rotation about its axis in a centrifuge. The bowl defines an outer arcuate wall plus an inner circumferential wall, spaced from the outer wall, to define a arcuate slot adapted for receiving blood components. Access tubing is adapted for communication with the slot. Preferably, an elongated, flexible, collapsible inner liner is provided in the slot. Individual access tubing also may communicate with an elongated container interior between the ends of the elongated, collapsible container. Furthermore, a portion of the slot may define the shape of an outwardly extending spiral, to provide an increasing gravitational field upon fluids therein as the fluid moves along the slot.

    摘要翻译： 血液成分分离装置包括适于在离心机中围绕其轴旋转的离心机碗。 碗定义了外弧形壁加上与外壁间隔开的内周壁，以限定适于接收血液成分的弧形槽。 接入管适用于与槽连通。 优选地，在狭槽中设置细长的，柔性的可折叠内衬。 单独的进入管也可以与细长的可收缩容器的端部之间的细长的容器内部连通。 此外，槽的一部分可以限定向外延伸的螺旋的形状，以在流体沿着狭槽移动时为其中的流体提供增加的重力场。

    System for metering nutrient media to cell culture containers and method
    20.
    发明授权
    System for metering nutrient media to cell culture containers and method 失效
    用于计量营养培养基至细胞培养容器和方法的系统

    公开(公告)号：US4829002A

    公开(公告)日：1989-05-09

    申请号：US862344

    申请日：1986-05-12

    申请人： Martha C. Pattillo ,  David V. Bacehowski ,  Arnold C. Bilstad ,  Herbert M. Cullis ,  T. Michael Dennehey ,  James W. Yang ,  William C. Brown

    发明人： Martha C. Pattillo ,  David V. Bacehowski ,  Arnold C. Bilstad ,  Herbert M. Cullis ,  T. Michael Dennehey ,  James W. Yang ,  William C. Brown

    IPC分类号： C12M3/00 ,  C12M1/00 ,  C12M1/26 ,  C12N5/00 ,  C12N5/10

    CPC分类号： C12M23/14 ,  C12M33/07

    摘要： A system for metering nutrient media to cell culture containers includes a media flow conduit which defines at one end means for substantially aseptic communication with the source of the media. In a preferred embodiment, sterile connectors may be used for essentially sterile conditions. A branch conduit extends from the flow conduit at a location spaced from the ends. The branch conduit communicates with means for receiving a predetermined-volume aliquot of media through the media flow conduit from said one end. The flow conduit also defines a portion downstream from the branch conduit, which communicates with at least one cell culture container, each container being a flexible bag. At least part of the flexible bag is made of a material capable of providing at least 2 times the oxygen diffusion and at least 2 times the carbon dioxide diffusion between the bag interior and exterior, compared with an identically-sized, sealed bag having polyethylene walls 0.013 inch thick.

    摘要翻译： 用于向细胞培养容器计量营养培养基的系统包括介质流动管道，其在一端限定用于与介质源实质上无菌的通信。 在优选的实施方案中，无菌连接器可用于基本上无菌的条件。 分支导管在与端部间隔开的位置处从流动管道延伸。 分支管道与用于从所述一端通过介质流动管道接收预定​​体积等分的介质的装置连通。 流动导管还限定了与至少一个细胞培养容器连通的分支导管下游的部分，每个容器是柔性袋。 与具有聚乙烯壁的相同尺寸的密封袋相比，柔性袋的至少一部分由能够提供至少2倍的氧扩散和袋内部和外部之间的二氧化碳扩散的材料制成。 0.013英寸厚