Thiazolyl-based compounds useful as kinase inhibitors
    12.
    发明申请
    Thiazolyl-based compounds useful as kinase inhibitors 有权
    可用作激酶抑制剂的噻唑基化合物

    公开(公告)号:US20070093537A1

    公开(公告)日:2007-04-26

    申请号:US11633337

    申请日:2006-12-04

    IPC分类号: A61K31/426

    CPC分类号: C07D277/56 C07D417/12

    摘要: The present invention provides thiazolyl-based compounds of formula (I), useful for treating p38 kinase-associated conditions, wherein ring A is phenyl or pyridyl, and X, Y, B, R2, R3, Z1 m and n are as defined herein. The invention further pertains to pharmaceutical compositions containing at least one compound according to the invention useful for treating p38 kinase-associated conditions, and methods of inhibiting the activity of p38 kinase in a mammal.

    摘要翻译: 本发明提供了可用于治疗p38激酶相关病症的式(I)的噻唑基类化合物,其中环A是苯基或吡啶基,X,Y,B,R 2, Z 3,Z 1和Z 3如本文所定义。 本发明还涉及含有至少一种可用于治疗p38激酶相关病症的本发明化合物的药物组合物,以及抑制哺乳动物中p38激酶活性的方法。

    Method and system for target lifetime
    19.
    发明申请
    Method and system for target lifetime 有权
    目标寿命的方法和系统

    公开(公告)号:US20050211549A1

    公开(公告)日:2005-09-29

    申请号:US10810534

    申请日:2004-03-26

    CPC分类号: H01J37/3482 C23C14/3407

    摘要: A method and system for determining a lifetime of a target for a physical vapor deposition tool (302), has, a mapping table (304a) of criteria for a minimum accumulating rate of Δ wafers fabricated by Δ target life for a target in the tool; and a database (304) recording Δ wafers fabricated by Δ target life for a target in the tool; and a computer (306) retrieving the criteria from the mapping table and entering the criteria in the database; and the tool (302) reporting Δ wafers fabricated by Δ target life for a target in the tool (302) for comparison with the criteria.

    摘要翻译: 一种用于确定物理气相沉积工具(302)的靶的寿命的方法和系统,具有用于针对目标的达标目标寿命制造的三角形晶片的最小累积速率的标准的映射表(304a) 工具; 以及数据库(304),记录用于所述工具中的目标的达标目标寿命制造的三角形晶片; 以及计算机(306),其从所述映射表检索所述准则并在所述数据库中输入所述准则; 并且所述工具(302)报告通过所述工具(302)中的目标的达标目标寿命制造的三角形晶片以与所述准则进行比较。

    Photogrammetric reconstruction of free-form objects with curvilinear structures
    20.
    发明申请
    Photogrammetric reconstruction of free-form objects with curvilinear structures 审中-公开
    具有曲线结构的自由形状物体的摄影测量重建

    公开(公告)号:US20050140670A1

    公开(公告)日:2005-06-30

    申请号:US10988883

    申请日:2004-11-15

    申请人: Hong Wu Yizhou Yu

    发明人: Hong Wu Yizhou Yu

    IPC分类号: G06T15/20 G06T17/20 G06T15/00

    CPC分类号: G06T15/205 G06T17/20

    摘要: The shapes of many natural or man-made objects have curve features. The images of such curves usually do not have sufficient distinctive features to apply conventional feature-based reconstruction algorithms. In this paper, we introduce a photogrammetric method for recovering free-form objects with curvilinear structures. Our method chooses to define the topology and recover a sparse 3D wireframe of the object first instead of directly recovering a surface or volume model. Surface patches covering the object are then constructed to interpolate the curves in this wireframe while satisfying certain heuristics such as minimal bending energy. The result is an object surface model with curvilinear structures from a sparse set of images. We can produce realistic texture-mapped renderings of the object model from arbitrary viewpoints. Reconstruction results on multiple real objects are presented to demonstrate the effectiveness of our approach.

    摘要翻译: 许多自然或人造物体的形状具有曲线特征。 这些曲线的图像通常没有足够的特征来应用常规的基于特征的重建算法。 在本文中,我们介绍了一种用于回收具有曲线结构的自由形状对象的摄影测量方法。 我们的方法选择定义拓扑并首先恢复对象的稀疏3D线框,而不是直接恢复曲面或体积模型。 然后构造覆盖物体的表面贴片,以便在满足某些启发式(如最小弯曲能量)的同时插入该线框中的曲线。 结果是具有来自稀疏图像集合的曲线结构的对象表面模型。 我们可以从任意观点生成对象模型的逼真的纹理映射渲染。 提出了多个真实物体的重建结果,以证明我们的方法的有效性。