公开(公告)号：US20180318781A1

公开(公告)日：2018-11-08

申请号：US16026771

申请日：2018-07-03

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Nephi D. Jones ,  Brandon M. Knudsen ,  Whitt F. Woods

IPC: B01F15/00 ,  C12M1/00 ,  B01F7/00 ,  C12M1/06 ,  C12M1/02 ,  C12M3/00 ,  C12M3/06 ,  B01F15/02 ,  B01F11/00 ,  B01F7/22 ,  B01F7/16

CPC classification number: B01F15/0085 ,  B01F7/001 ,  B01F7/00725 ,  B01F7/1615 ,  B01F7/1695 ,  B01F7/22 ,  B01F11/0008 ,  B01F11/0017 ,  B01F15/00733 ,  B01F15/0074 ,  B01F15/00772 ,  B01F15/0203 ,  B01F15/0295 ,  B01F2015/0221 ,  C12M23/14 ,  C12M23/48 ,  C12M23/52 ,  C12M27/00 ,  C12M27/02 ,  C12M27/16 ,  C12M29/06

Abstract: A method for mixing a fluid includes: dispensing a first volume of a fluid into a flexible container, the flexible container being at least partially disposed within the chamber of a support housing; repeatedly moving the support housing and the flexible container contained therein so as to mix the first volume of fluid within the flexible container; adding further fluid into the flexible container after moving the support housing to form a second volume of fluid; and manipulating a mixing element within the flexible container so as to mix the second volume of fluid.

公开(公告)号：US10035116B2

公开(公告)日：2018-07-31

申请号：US14405126

申请日：2013-02-26

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Nephi D. Jones ,  Brandon M. Knudsen ,  Whitt F. Woods

IPC: B01F7/16 ,  B01F15/00 ,  B01F7/00 ,  B01F7/22 ,  B01F11/00 ,  B01F15/02 ,  C12M1/00 ,  C12M1/06 ,  C12M3/06 ,  C12M3/00 ,  C12M1/02

CPC classification number: B01F15/0085 ,  B01F7/001 ,  B01F7/00725 ,  B01F7/1615 ,  B01F7/1695 ,  B01F7/22 ,  B01F11/0008 ,  B01F11/0017 ,  B01F15/00733 ,  B01F15/0074 ,  B01F15/00772 ,  B01F15/0203 ,  B01F15/0295 ,  B01F2015/0221 ,  C12M23/14 ,  C12M23/48 ,  C12M23/52 ,  C12M27/00 ,  C12M27/02 ,  C12M27/16 ,  C12M29/06

Abstract: A fluid mixing system that can be used as a bioreactor or fermentor can include a stand and a support housing pivotably mounted to the stand. The support housing bounds a chamber into which a container assembly is removably disposed. The container assembly includes a flexible bag bounding a compartment adapted to hold a fluid and a mixing element disposed within the compartment. The support housing can be tilted relative to the stand for ease in insertion of the container assembly. The support housing can also be repeatedly rocked relative to the stand form mixing fluid within the container assembly.

公开(公告)号：US20170354901A1

公开(公告)日：2017-12-14

申请号：US15521227

申请日：2015-10-23

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Scott P. Collins ,  Christopher D Brau ,  Nephi D. Jones

IPC: B01D11/04 ,  G01N1/34

CPC classification number: B01D11/0423 ,  B01D11/043 ,  B01D11/0449 ,  B01D11/0457 ,  G01N1/34 ,  G01N2001/4061

Abstract: A sample purification system includes a container assembly bounding a sample purification compartment and having an upper end and an opposing lower end, the sample purification compartment comprising mixing zones and settling zones. A plurality of shielding elements are positioned within the sample purification compartment so as to at least partially separate adjacent mixing zones and settling zones or separate adjacent mixing zones, the mixing zones being in fluid communication with the settling zones. A mixing element is disposed within each mixing zone. An acoustic wave settler is aligned with a portion of the container assembly, the acoustic wave settler being configured to emit an acoustic wave through the portion of the container assembly and a mixture disposed therein, the acoustic wave coalescing fluid phase droplets disposed in the mixture to increase the buoyancy or density of the fluid phase droplets.

公开(公告)号：US20170246603A1

公开(公告)日：2017-08-31

申请号：US15596952

申请日：2017-05-16

Applicant: Life Technologies Corporation

Inventor： Michael E. Goodwin ,  Nephi D. Jones ,  Jeremy K. Larsen

IPC: B01F15/00 ,  B01F7/00 ,  C12M1/00 ,  B01F5/04 ,  B01F7/22 ,  C12M1/12 ,  C12M1/04 ,  B01F3/04 ,  B01F13/02

CPC classification number: B01F15/0085 ,  B01F3/04269 ,  B01F3/04439 ,  B01F3/04829 ,  B01F5/04 ,  B01F7/00341 ,  B01F7/22 ,  B01F11/0082 ,  B01F13/0255 ,  B01F2003/04276 ,  B01F2003/04297 ,  B01F2003/04312 ,  B01F2003/04326 ,  B01F2003/04361 ,  B01F2003/04382 ,  B01F2003/04397 ,  B01F2215/0073 ,  C12M23/14 ,  C12M23/20 ,  C12M23/26 ,  C12M27/04 ,  C12M29/06 ,  C12M37/00

Abstract: A container system includes a collapsible bag having an interior surface at least partially bounding a chamber, the chamber being adapted to hold a fluid. A sparger is disposed within the chamber of the bag, the sparger bounding a compartment and having an inside edge that encircles an opening passing through the sparger. At least a portion of the sparger is gas permeable. A tubular member is coupled to the sparger and is in communication with the compartment. A shaft passes into the chamber of the bag and through the opening of the sparger. A mixing element is secured to the shaft and is disposed within the chamber of the bag.

公开(公告)号：US09540606B2

公开(公告)日：2017-01-10

申请号：US14109684

申请日：2013-12-17

Applicant: Life Technologies Corporation ,  Baxalta Incorporated ,  Baxalta GmbH

Inventor： Kurt T. Kunas ,  Robert V. Oakley ,  Fauad F. Hasan ,  Michael E. Goodwin ,  Jeremy K. Larsen ,  Nephi D. Jones

IPC: C12M1/06 ,  B01F7/00 ,  B01F7/16 ,  B01F7/22 ,  B01F15/00 ,  C12M1/00

CPC classification number: C12M23/14 ,  B01F7/001 ,  B01F7/1695 ,  B01F7/22 ,  B01F15/00006 ,  B01F15/00831 ,  B01F15/0085 ,  B01F2215/0073 ,  C12M23/00 ,  C12M23/06 ,  C12M23/26 ,  C12M23/28 ,  C12M27/02 ,  C12M29/06 ,  Y10T29/49826

Abstract: A method of mixing a fluid includes positioning a flexible bag into the chamber of a support housing, the support housing having a plurality of baffles positioned so that the bag folds around the baffles. A fluid is delivered into a compartment of the flexible bag. A mixing element, such as an impeller, is moved within the compartment of the flexible bag so as to mix the fluid therein.

Abstract translation: 混合流体的方法包括将柔性袋定位到支撑壳体的室中，所述支撑壳体具有多个挡板，所述挡板被定位成使得袋围绕挡板折叠。 将流体输送到柔性袋的隔室中。 诸如叶轮的混合元件在柔性袋的隔室内移动，以便在其中混合流体。

公开(公告)号：US09284524B2

公开(公告)日：2016-03-15

申请号：US14088140

申请日：2013-11-22

Applicant: Life Technologies Corporation

Inventor： Clinton C. Staheli ,  Nephi D. Jones ,  Michael E. Goodwin

IPC: C12M1/06 ,  C12M1/00 ,  B01F3/04 ,  B01F7/16 ,  B01F7/18 ,  B01F15/00 ,  C12M1/12 ,  B01D47/05 ,  C12N1/10 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N5/00 ,  C12N5/04 ,  B01D5/00 ,  B01F7/00 ,  B01F15/06

CPC classification number: C12M23/14 ,  B01D5/0072 ,  B01D47/05 ,  B01F3/04241 ,  B01F3/04531 ,  B01F7/00691 ,  B01F7/1695 ,  B01F7/18 ,  B01F7/22 ,  B01F15/00071 ,  B01F15/00831 ,  B01F15/0085 ,  B01F15/065 ,  B01F2003/04191 ,  B01F2003/04297 ,  B01F2003/04673 ,  B01F2003/04865 ,  B01F2003/04872 ,  B01F2003/04879 ,  B01F2003/04893 ,  B01F2003/04921 ,  B01F2015/061 ,  B01F2215/0073 ,  C12M23/26 ,  C12M23/34 ,  C12M27/02 ,  C12M29/00 ,  C12M29/06 ,  C12M29/24 ,  C12M37/00 ,  C12M41/14 ,  C12M41/18 ,  C12N1/10 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N5/00 ,  C12N5/04 ,  C12N5/10 ,  F28B1/02 ,  F28F3/12 ,  F28F21/06 ,  F28F2255/02

Abstract: A heat exchanger system includes a heat exchanger having a body plate with a first side face and an opposing second side face, the body plate bounding a fluid channel disposed between the opposing side faces and extending between an inlet port and an outlet port, and a first side plate having an inside face. A flexible first bag includes of one or more sheets of polymeric material, the first bag bounding a fluid pathway that extends between a fluid inlet and a fluid outlet, the first bag being removably retained between the body plate and the first side plate so that at least a portion of the first bag rests against the first side face of the body plate when the fluid pathway of the first bag is filled with a fluid.

Abstract translation: 热交换器系统包括具有主板的热交换器，该主体板具有第一侧面和相对的第二侧面，主体板限定设置在相对侧面之间并在入口和出口之间延伸的流体通道， 第一侧板具有内表面。 柔性第一袋包括一片或多片聚合物材料，第一袋包围在流体入口和流体出口之间延伸的流体通道，第一袋可移除地保持在主体板和第一侧板之间，使得在 当第一袋的流体通道充满流体时，第一袋的至少一部分靠在主体板的第一侧面上。

公开(公告)号：US20150265958A1

公开(公告)日：2015-09-24

申请号：US14587976

申请日：2014-12-31

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Jason D. Brown ,  Clinton C. Staheli ,  Nephi D. Jones

IPC: B01D46/00

Abstract: A filter assembly includes a casing having of a polymeric film and bounding a compartment, the casing having an inlet opening communicating with the compartment and a first outlet opening communicating with the compartment. A first filter includes a porous filter body through which gas can pass and has a pore size smaller than 1 μm, the first filter being coupled with the casing so that the filter body is at least partially disposed within compartment of the casing and so that gas passing through the compartment of the casing from the inlet opening to the first outlet opening must pass through the filter body.

Abstract translation: 过滤器组件包括具有聚合物膜并且限定隔室的壳体，所述壳体具有与隔室连通的入口开口和与隔室连通的第一出口开口。 第一过滤器包括多孔过滤器主体，气体可以通过该多孔过滤器主体，孔径小于1μm，第一过滤器与壳体联接，使得过滤器主体至少部分地设置在壳体的隔室内， 穿过套管的隔室从入口开口到第一出口开口必须通过过滤器本体。

公开(公告)号：US20250144280A1

公开(公告)日：2025-05-08

申请号：US19018930

申请日：2025-01-13

Applicant: Life Technologies Corporation ,  Life Technologies AS

Inventor： Lars Norderhaug ,  Nephi D. Jones ,  Angel Varela-Rohena

IPC: A61M1/36 ,  B01L3/00 ,  B03C1/01 ,  B03C1/28 ,  B03C1/30 ,  C07K16/28 ,  C12M1/00 ,  C12M1/12 ,  C12M1/26 ,  C12M3/00

Abstract: A magnetic particle separation system includes a magnetic field generating device having an upper surface with a receiving area formed thereon; and a magnetic field generating element disposed beneath the upper surface, the magnetic field generating element being configured to produce a magnetic field above the upper surface. A container assembly is disposed on the upper surface and includes: a flexible container having an outer wall with an interior surface that at least partially bounds an internal compartment, the outer wall having a front side and an opposing back side with the internal compartment disposed therebetween; a fluid inlet extending through the outer wall at the front side; a fluid outlet extending through the outer wall at the front side; and a first partition projecting into the internal compartment from the front side between the fluid inlet and the fluid outlet.

公开(公告)号：US20240279580A1

公开(公告)日：2024-08-22

申请号：US18651331

申请日：2024-04-30

Applicant: Life Technologies Corporation

Inventor： Clinton C. Staheli ,  Nephi D. Jones ,  Michael E. Goodwin

IPC: C12M1/00 ,  B01D5/00 ,  B01D47/05 ,  B01F23/231 ,  B01F23/233 ,  B01F23/237 ,  B01F27/2121 ,  B01F27/88 ,  B01F27/90 ,  B01F27/91 ,  B01F35/10 ,  B01F35/51 ,  B01F35/513 ,  B01F35/90 ,  B01F35/92 ,  B01F101/44 ,  C12M1/02 ,  C12M1/06 ,  C12M1/12 ,  C12N1/10 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N5/00 ,  C12N5/04 ,  C12N5/10 ,  F28B1/02 ,  F28D21/00 ,  F28F3/12 ,  F28F21/06

CPC classification number: C12M23/14 ,  B01D5/0072 ,  B01D47/05 ,  B01F23/23125 ,  B01F23/233 ,  B01F27/2121 ,  B01F27/88 ,  B01F27/90 ,  B01F27/91 ,  B01F35/146 ,  B01F35/51 ,  B01F35/513 ,  B01F35/92 ,  C12M23/26 ,  C12M23/34 ,  C12M27/02 ,  C12M29/00 ,  C12M29/06 ,  C12M29/24 ,  C12M37/00 ,  C12M41/14 ,  C12M41/18 ,  C12N1/10 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N5/00 ,  C12N5/04 ,  F28B1/02 ,  F28F3/12 ,  F28F21/06 ,  F28F21/065 ,  B01F23/231151 ,  B01F23/231262 ,  B01F23/23362 ,  B01F23/23761 ,  B01F23/237611 ,  B01F23/237612 ,  B01F23/23762 ,  B01F23/23765 ,  B01F2035/98 ,  B01F2101/44 ,  C12N5/10 ,  F28D2021/0063 ,  F28F2255/02

Abstract: A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.

公开(公告)号：US20230356158A1

公开(公告)日：2023-11-09

申请号：US18353754

申请日：2023-07-17

Applicant: Life Technologies Corporation

Inventor： Jeffery C. HURD ,  Nephi D. Jones ,  Jacob D. Lee

IPC: B01F27/231 ,  C12M1/34 ,  C12M1/00 ,  B01F23/231 ,  B01F27/07 ,  B01F27/113 ,  B01F27/213 ,  B01F27/2111 ,  B01F27/2121 ,  B01F27/2122 ,  B01F33/00 ,  B01F35/513 ,  C12M1/06

CPC classification number: B01F27/2312 ,  C12M41/44 ,  C12M23/26 ,  B01F23/2311 ,  B01F27/071 ,  B01F27/113 ,  B01F27/213 ,  B01F27/2111 ,  B01F27/2121 ,  B01F27/2122 ,  B01F33/86 ,  B01F35/513 ,  C12M23/14 ,  C12M27/02 ,  B01F23/231151 ,  B01F2101/22

Abstract: A liquid mixing system includes a support housing at least partially bounding a compartment. A mount is secured to the support housing. A drive motor assembly is configured to engage a drive shaft for moving the drive shaft within the compartment of the support housing. A four bar linkage system extends between the mount and the drive motor assembly, the four bar linkage system being movable between a first position wherein the drive motor assembly is disposed at a first elevation and a second position wherein the drive motor assembly is disposed at a second elevation that is different from the first elevation.