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公开(公告)号：US09126042B2
公开(公告)日：2015-09-08
申请号：US14484701
申请日：2014-09-12
Applicant: NeuroPace, Inc.
Inventor： Thomas K. Tcheng , Robert E. Fischell , Benjamin D. Pless
CPC classification number: A61N1/36067 , A61N1/36135
Abstract: An implantable neurostimulator system for treating movement disorders includes a sensor, a detection subsystem capable of identifying episodes of a movement disorder by analyzing a signal received from the sensor, and a therapy subsystem capable of supplying therapeutic electrical stimulation to treat the movement disorder. The system treats movement disorders by detecting physiological conditions characteristic of an episode of symptoms of the movement disorder and selectively initiating therapy when such conditions are detected.
Abstract translation: 用于治疗运动障碍的可植入神经刺激器系统包括传感器，能够通过分析从传感器接收的信号来识别运动障碍发作的检测子系统，以及能够提供治疗性电刺激以治疗运动障碍的治疗子系统。 该系统通过检测运动障碍症状发作特征的生理条件来治疗运动障碍，并且当检测到这种病症时选择性地开始治疗。
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12.发明申请公开(公告)号：US20130184780A1
公开(公告)日：2013-07-18
申请号：US13784569
申请日：2013-03-04
Applicant: NeuroPace, Inc.
Inventor： Benjamin D. Pless , Thomas K. Tcheng
IPC: A61N1/36
CPC classification number: A61N1/36135 , A61B5/0006 , A61B5/0022 , A61B5/0031 , A61B5/021 , A61B5/026 , A61B5/04012 , A61B5/0476 , A61B5/0488 , A61B5/076 , A61B5/14542 , A61B5/14546 , A61B5/4812 , A61B5/4836 , A61B5/686 , A61B5/743 , A61M5/14276 , A61N1/0529 , A61N1/0531 , A61N1/0539 , A61N1/36064 , A61N1/36067 , A61N1/36078 , A61N1/36139
Abstract: An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied depending on various sensor measurements, calculations, inferences, and device states (including elapsed times and times of day) to deliver an appropriate course of therapy under the circumstances.
Abstract translation: 适用于为各种神经障碍提供治疗的可植入神经刺激器系统能够基于要递送治疗的上下文（生理或其他）改变治疗递送策略。 根据各种传感器测量，计算，推断和设备状态（包括经过时间和时间），在这种情况下提供适当的治疗方案，响应和预定的治疗方法可以不同。
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13.发明申请公开(公告)号：US20130102833A1
公开(公告)日：2013-04-25
申请号：US13714387
申请日：2012-12-13
Applicant: NEUROPACE, INC.
Inventor： Michael Sasha John , Benjamin D. Pless , Brett Wingeier
CPC classification number: A61N1/36139 , A61B5/0031 , A61B5/02 , A61B5/0476 , A61B5/14553 , A61B5/1459 , A61B5/4094 , A61B5/6868 , A61B5/7217 , A61B8/06 , A61B8/12 , A61B8/488 , A61F7/00 , A61F7/12 , A61N1/36057 , A61N1/36064 , A61N1/36082 , A61N1/36135 , A61N2/006 , A61N2/02 , A61N5/0622 , A61N7/00 , A61N2007/0043
Abstract: A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required.
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公开(公告)号：US09649049B2
公开(公告)日：2017-05-16
申请号：US14937725
申请日：2015-11-10
Applicant: NeuroPace, Inc.
Inventor： Benjamin D. Pless , David R. Fischell , Barbara Gibb , Lisa Guzzo , Adrian R. M. Upton
IPC: A61B5/00 , A61B5/07 , A61N1/36 , A61N1/372 , A61B5/0482 , A61B5/0478
CPC classification number: A61B5/076 , A61B5/0006 , A61B5/0031 , A61B5/0478 , A61B5/0482 , A61B5/4094 , A61B5/686 , A61B5/742 , A61B5/7475 , A61N1/36064 , A61N1/36135 , A61N1/37252 , A61N1/37258 , A61N1/37282 , G06F19/00
Abstract: An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.
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15.发明授权公开(公告)号：US09597032B2
公开(公告)日：2017-03-21
申请号：US15047475
申请日：2016-02-18
Applicant: NeuroPace, Inc.
Inventor： Felice Sun , Benjamin D. Pless , Barbara Gibb
IPC: A61B5/048 , A61B5/00 , A61B5/0478 , A61N1/36 , A61B5/01 , A61B5/0205 , A61B5/026 , A61B5/0452 , A61B5/1455 , A61B5/04 , A61B5/0476 , A61B5/024 , A61B5/11
CPC classification number: A61B5/4812 , A61B5/01 , A61B5/0205 , A61B5/02438 , A61B5/026 , A61B5/04012 , A61B5/0452 , A61B5/0476 , A61B5/0478 , A61B5/11 , A61B5/1118 , A61B5/14551 , A61B5/4815 , A61B5/686 , A61N1/36082 , A61N1/36135 , G06F19/00
Abstract: Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.
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Patent Agency Ranking
公开(公告)号：US08934980B2
公开(公告)日：2015-01-13
申请号：US13784569
申请日：2013-03-04
Applicant: NeuroPace, Inc.
Inventor： Benjamin D. Pless , Thomas K. Tcheng
CPC classification number: A61N1/36135 , A61B5/0006 , A61B5/0022 , A61B5/0031 , A61B5/021 , A61B5/026 , A61B5/04012 , A61B5/0476 , A61B5/0488 , A61B5/076 , A61B5/14542 , A61B5/14546 , A61B5/4812 , A61B5/4836 , A61B5/686 , A61B5/743 , A61M5/14276 , A61N1/0529 , A61N1/0531 , A61N1/0539 , A61N1/36064 , A61N1/36067 , A61N1/36078 , A61N1/36139
Abstract: An implantable neurostimulator system adapted to provide therapy for various neurological disorders is capable of varying therapy delivery strategies based on the context, physiological or otherwise, into which the therapy is to be delivered. Responsive and scheduled therapies can be varied depending on various sensor measurements, calculations, inferences, and device states (including elapsed times and times of day) to deliver an appropriate course of therapy under the circumstances.
Abstract translation: 适用于为各种神经障碍提供治疗的可植入神经刺激器系统能够基于要递送治疗的上下文（生理或其他）改变治疗递送策略。 根据各种传感器测量，计算，推断和设备状态（包括经过时间和时间），在这种情况下提供适当的治疗方案，响应和预定的治疗方法可以不同。
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17.发明授权Modulation and analysis of cerebral perfusion in epilepsy and other neurological disorders 有权癫痫和其他神经系统疾病中脑灌注的调节和分析公开(公告)号：US08771194B2
公开(公告)日：2014-07-08
申请号：US13714387
申请日：2012-12-13
Applicant: NeuroPace, Inc.
Inventor： Michael S. John , Benjamin D. Pless , Brett M. Wingeier
CPC classification number: A61N1/36139 , A61B5/0031 , A61B5/02 , A61B5/0476 , A61B5/14553 , A61B5/1459 , A61B5/4094 , A61B5/6868 , A61B5/7217 , A61B8/06 , A61B8/12 , A61B8/488 , A61F7/00 , A61F7/12 , A61N1/36057 , A61N1/36064 , A61N1/36082 , A61N1/36135 , A61N2/006 , A61N2/02 , A61N5/0622 , A61N7/00 , A61N2007/0043
Abstract: A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required.
Abstract translation: 一种包括能够调节脑血流以治疗癫痫和其他神经障碍的可植入神经刺激器装置的系统。 在一个实施方案中，系统能够响应于测量和其他观察到的条件而调节脑血流量（也称为脑灌注）。 根据临床要求的根据本发明的系统和方法可以增加或减少灌注。
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18.发明授权公开(公告)号：US08694106B2
公开(公告)日：2014-04-08
申请号：US13781186
申请日：2013-02-28
Applicant: NeuroPace, Inc.
Inventor： Benjamin D. Pless
CPC classification number: A61N1/36064 , A61N1/36082 , A61N1/36135 , A61N1/36178
Abstract: This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation strategies.
Abstract translation: 这是一种神经刺激器，其被配置为在施加这些脉冲的突发期间使用某些刺激策略来治疗癫痫和其他神经障碍，特别是改变各种脉冲参数。 本发明包括体现这些刺激策略的过程。
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19.发明申请公开(公告)号：US20130184604A1
公开(公告)日：2013-07-18
申请号：US13783143
申请日：2013-03-01
Applicant: NeuroPace, Inc.
Inventor： Benjamin D. Pless , David R. FISCHELL , Barbara Gibb , Lisa Guzzo , Adrian R.M. Upton
IPC: A61N1/36 , A61B5/0482
CPC classification number: A61B5/076 , A61B5/0006 , A61B5/0031 , A61B5/0478 , A61B5/0482 , A61B5/4094 , A61B5/686 , A61B5/742 , A61B5/7475 , A61N1/36064 , A61N1/36135 , A61N1/37252 , A61N1/37258 , A61N1/37282 , G06F19/00
Abstract: An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.
Abstract translation: 交互式可植入医疗装置系统包括能够与可植入医疗装置进行双向通信和交互的可植入医疗装置和能够启用网络的外部装置。 外部设备被编程为与其他类似启用的设备进行交互。 该系统通过消除对植入式医疗设备询问和编程的不必要的地理限制，以及允许患者，医生和其他用户访问医疗记录，历史和信息以及随时接收状态和护理相关的警报和消息来促进改善患者护理 可以访问通信网络。
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20.发明申请公开(公告)号：US20130178914A1
公开(公告)日：2013-07-11
申请号：US13781186
申请日：2013-02-28
Applicant: NeuroPace, Inc.
Inventor： Benjamin D. Pless
IPC: A61N1/36
CPC classification number: A61N1/36064 , A61N1/36082 , A61N1/36135 , A61N1/36178
Abstract: This is a neurostimulator that is configured to treat epilepsy and other neurological disorders using certain stimulation strategies, particularly changing various pulse parameters, during the imposition of a burst of those pulses. The invention includes the processes embodying those stimulation strategies.
Abstract translation: 这是一种神经刺激器，其被配置为在施加这些脉冲的突发期间使用某些刺激策略来治疗癫痫和其他神经障碍，特别是改变各种脉冲参数。 本发明包括体现这些刺激策略的过程。
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