Use of Aptamers in Liquid Chromatography and Liquid Chromatography - Mass Spectrometry
    13.
    发明申请
    Use of Aptamers in Liquid Chromatography and Liquid Chromatography - Mass Spectrometry 审中-公开
    在液相色谱和液相色谱中使用适配子 - 质谱

    公开(公告)号:US20140162248A1

    公开(公告)日:2014-06-12

    申请号:US14101624

    申请日:2013-12-10

    IPC分类号: C12N15/115 C12Q1/68

    摘要: The present disclosure relates to the use of aptamers in solid phase extraction, chromatography and chromatography-mass spectrometry systems. More specifically, the present disclosure relates to the use of aptamers in SPE and chromatography systems to selectively retain, extract and/or pre-concentrate target molecule(s) having a specific affinity for the particular aptamer(s). The target molecule(s) can be further analyzed by mass spectrometry with limited interferences and/or enhanced sensitivity.

    摘要翻译: 本公开涉及在固相萃取,色谱和色谱 - 质谱系统中使用适体。 更具体地说,本公开内容涉及在SPE和色谱系统中适体的选择性保留,提取和/或预浓缩对于特定适体具有特异性亲和力的靶分子的用途。 目标分子可以通过质谱进一步分析,有限的干扰和/或增强的灵敏度。

    Morphology-controlled olefin polymerization catalyst formed from an
emulsion
    16.
    发明授权
    Morphology-controlled olefin polymerization catalyst formed from an emulsion 失效
    由乳液形成的形态控制的烯烃聚合催化剂

    公开(公告)号:US5955396A

    公开(公告)日:1999-09-21

    申请号:US682397

    申请日:1996-07-17

    IPC分类号: C08F4/623 C08F4/64 C08F10/00

    CPC分类号: C08F10/00

    摘要: A solid, hydrocarbon-insoluble, olefin-polymerization catalyst component having substantially uniform particles useful in polymerizing olefins is formed by:reacting a magnesium-containing compound with carbon dioxide or sulfur dioxide;forming a two-phase mixture of the resulting magnesium-containing compound with a suitable liquid hydrocarbon-miscible phase and a suitable polar solvent phase;forming particles by adding the two-phase mixture after vigorous agitation to a liquid hydrocarbon; andcontacting the formed particles at least once with a transition metal halide in the presence of an electron donor.

    摘要翻译: 通过使含镁化合物与二氧化碳或二氧化硫反应形成具有用于聚合烯烃的基本上均匀的颗粒的固体,不溶于烃的烯烃聚合催化剂组分; 形成所得含镁化合物与合适的液体烃混溶相和合适的极性溶剂相的两相混合物; 通过在剧烈搅拌后将两相混合物加入到液体烃中形成颗粒; 并在电子给体的存在下使形成的颗粒与过渡金属卤化物接触至少一次。

    Heterometallic thiocubanes (C-2044)
    19.
    发明授权
    Heterometallic thiocubanes (C-2044) 失效
    异十二烷(C-2044)

    公开(公告)号:US4730064A

    公开(公告)日:1988-03-08

    申请号:US870772

    申请日:1986-06-02

    摘要: This invention relates to heterometallic thiocubane compositions containing the M.sub.2.sup.1 M.sub.2.sup.2 S.sub.4 cluster core and methods of making them wherein M.sup.1 is Re, V, Mo or W and M.sup.2 is Co, Cr, Cu, Ni or Fe but preferably Co. More particularly, the invention relates to compositions of the formula M.sub.2.sup.2 M.sub.2.sup.2 S.sub.4 L.sub.2.sup.1 L.sub.2.sup.2 L.sub.2.sup.3 wherein M.sup.1 and M.sup.2 are as above, L.sup.1 is a bidentate sulfur or nitrogen bearing ligand (most preferably a dialkyldithiocarbamate), L.sup.2 is optional but may be an O, N, P or S-containing monodentate donor ligand, and L.sup.3 may be CO, a monodentate anion ligand such as a halide (preferably C1), mercaptide or alkoxide, or another O, N, P, or S containing monodentate donor ligand. The compositions are suitable for making active hydrotreating catalysts.

    摘要翻译: 本发明涉及含有M21M22S4簇核的异金属巯基组合物及其制备方法,其中M1为Re,V,Mo或W,M2为Co,Cr,Cu,Ni或Fe,但优选为Co。更具体地说,本发明涉及 式M22M22S4L21L22L23的组合物,其中M1和M2如上,L1是双齿硫或带氮配体(最优选二烷基二硫代氨基甲酸酯),L2是任选的,但可以是含O,N,P或S的单齿供体配体,以及 L3可以是CO,单齿阴离子配体如卤化物(优选C1),硫醇盐或醇盐,或另一种含O,N,P或S的单齿供体配体。 该组合物适用于制备活性加氢处理催化剂。