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    Oligodendrocyte determination genes and uses thereof
    11.
    发明授权
    Oligodendrocyte determination genes and uses thereof 有权
    少突胶质细胞测定基因及其用途

    公开(公告)号：US07732206B2

    公开(公告)日：2010-06-08

    申请号：US11397200

    申请日：2006-04-04

    申请人： David J. Anderson ,  Qiao Zhou

    发明人： David J. Anderson ,  Qiao Zhou

    IPC分类号： C12N15/00 ,  C12N5/071 ,  C12N5/00

    CPC分类号： C12N5/0622 ,  C12N2506/02 ,  C12N2506/08 ,  C12N2510/00

    摘要： The invention relates to methods and reagents for promoting the differentiation of oligodendrocytes from stem cells, by co-activating the Olig genes and the Nkx2.2 genes, and the use of the differentiated oligodendrocytes thus obtained in treating diseases, such as Multiple Sclerosis (MS). The invention also relates to the use of OLPs and oligodendrocytes thus obtained for drug screening.

    摘要翻译： 本发明涉及用于通过共同活化Olig基因和Nkx2.2基因促进少突胶质细胞从干细胞分化的方法和试剂，以及由此获得的分化的少突胶质细胞在治疗诸如多发性硬化（MS） ）。 本发明还涉及由此获得的OLP和少突胶质细胞用于药物筛选的用途。

    ELECTRO-HYDRAULIC ACTUATOR MOUNTING
    13.
    发明申请
    ELECTRO-HYDRAULIC ACTUATOR MOUNTING 有权
    电动液压驱动器安装

    公开(公告)号：US20090041599A1

    公开(公告)日：2009-02-12

    申请号：US12186215

    申请日：2008-08-05

    申请人： Timothy Sweeney ,  Paul T. Kubinski ,  David J. Anderson

    发明人： Timothy Sweeney ,  Paul T. Kubinski ,  David J. Anderson

    IPC分类号： F04B35/04

    CPC分类号： F04B35/045

    摘要： An electro-hydraulic actuator includes a hydraulic pump, an electric motor operatively connected to the hydraulic pump and operable for driving the pump, an actuator moveable in response to fluid flow from the pump, and a housing for the pump, electric motor and actuator. The housing has a base member that is adapted to be modified into various configurations for forming an attachment interface for mounting of the electro-hydraulic actuator.

    摘要翻译： 电动液压致动器包括液压泵，可操作地连接到液压泵并可用于驱动泵的电动马达，响应于来自泵的流体流动而可移动的致动器以及用于泵，电动马达和致动器的壳体。 壳体具有适于被修改成各种构造的基部构件，用于形成用于安装电动液压致动器的附接界面。

    Systems and Methods for Inducing Intelligible Hearing
    14.
    发明申请
    Systems and Methods for Inducing Intelligible Hearing 审中-公开
    诱导智能听力的系统与方法

    公开(公告)号：US20080300652A1

    公开(公告)日：2008-12-04

    申请号：US10592916

    申请日：2005-03-17

    申请人： Hubert H. Lim ,  David J. Anderson ,  James A. Wiler ,  Jamille F. Hetke

    发明人： Hubert H. Lim ,  David J. Anderson ,  James A. Wiler ,  Jamille F. Hetke

    IPC分类号： H04R25/00

    CPC分类号： A61N1/36036

    摘要： The present invention comprises systems and methods for inducing auditory sensations in patients by stimulating the inferior colliculus of the mammalian midbrain. In some embodiments, the invention comprises an auditory prosthesis system comprising a microphone, a sound processor, a current stimulator, and one or more stimulating electrodes disposed in the inferior colliculus of a mammal. At least one of the stimulating electrodes may be comprised of one or more shanks, each shank comprised of one or more stimulation sites. In some embodiments, without limitation, the invention comprises methods of inducing auditory sensation in a mammal, comprising the steps of providing a microphone, a sound processor, and a current stimulator; providing one or more stimulating electrodes each comprised of two or more shanks, each shank comprised of one or more stimulation sites; disposing at least one stimulating electrode in the inferior colliculus of a mammal; and stimulating at least one isofrequency lamina of the inferior colliculus by applying an electrical signal through at least one of the stimulation sites.

    摘要翻译： 本发明包括通过刺激哺乳动物中脑的下丘来诱导患者的听觉的系统和方法。 在一些实施例中，本发明包括听觉假体系统，其包括麦克风，声音处理器，电流刺激器以及设置在哺乳动物下丘中的一个或多个刺激电极。 刺激电极中的至少一个可以由一个或多个柄构成，每个柄由一个或多个刺激部位组成。 在一些实施例中，但不限于，本发明包括在哺乳动物中诱发听觉的方法，包括提供麦克风，声音处理器和电流刺激器的步骤; 提供一个或多个刺激电极，每个刺激电极由两个或多个柄组成，每个柄由一个或多个刺激部位组成; 在哺乳动物的下丘中设置至少一个刺激电极; 以及通过施加通过至少一个所述刺激部位的电信号来刺激所述下丘的至少一个异频层。

    Method and system for dynamically varying intermediation functions in a communication path between a content server and a client station
    15.
    发明授权
    Method and system for dynamically varying intermediation functions in a communication path between a content server and a client station 有权
    用于在内容服务器和客户端站之间的通信路径中动态地改变中介功能的方法和系统

    公开(公告)号：US07360210B1

    公开(公告)日：2008-04-15

    申请号：US10189720

    申请日：2002-07-03

    申请人： Daniel S. Vacanti ,  Martin Geddes ,  Todd M. Conley ,  David J. Anderson ,  Neil E. Lowrey

    发明人： Daniel S. Vacanti ,  Martin Geddes ,  Todd M. Conley ,  David J. Anderson ,  Neil E. Lowrey

    IPC分类号： G06F9/44

    CPC分类号： H04L67/2804

    摘要： A method and system for dynamically varying intermediation functions in a communication path between a content server and a client station. An intermediation system within the communication path receives an HTTP message and detects an intermediation-variance instruction within the message. In response, the intermediation system varies a default set of intermediation logic, such as by removing, changing or adding one or more intermediation triggers and/or intermediation actions. In turn, the intermediation system applies the variant intermediation logic in response to the HTTP message and/or in response to subsequent HTTP messages.

    摘要翻译： 一种用于在内容服务器和客户站之间的通信路径中动态地改变中介功能的方法和系统。 通信路径内的中介系统接收到HTTP消息，并检测消息内的中介方差指令。 作为响应，中介系统改变默认的中介逻辑集合，例如通过移除，改变或添加一个或多个中介触发器和/或中介动作。 反过来，中介系统响应于HTTP消息和/或响应于后续的HTTP消息来应用变体中介逻辑。