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    Battery system
    11.
    发明申请
    Battery system 审中-公开
    电池系统

    公开(公告)号：US20080268330A1

    公开(公告)日：2008-10-30

    申请号：US11905170

    申请日：2007-09-27

    Applicant: Scott A. Hansen ,  Nels R. Smith ,  Michael G. Andrew ,  Thomas J. Dougherty ,  Majid Taghikhani ,  Elisabet A. Anderson

    Inventor： Scott A. Hansen ,  Nels R. Smith ,  Michael G. Andrew ,  Thomas J. Dougherty ,  Majid Taghikhani ,  Elisabet A. Anderson

    IPC: H01M2/10

    CPC classification number: H01M2/305 ,  B60K1/04 ,  B60K2001/0455 ,  H01M2/202 ,  H01M2/206 ,  H01M2/30 ,  H01M10/02 ,  H01M10/0413 ,  H01M10/4207

    Abstract: A battery system for a vehicle includes a battery module having a plurality of cells electrically coupled together and a first conductive element for electrically coupling the battery module to other elements in the battery system. The battery system also has a base configured for securing the battery module in place in the vehicle. The base includes a second conductive element for electrically coupling the base to the first conductive element, and a rotatable arm for securing the battery module in place relative to the base. The first conductive element is configured to contact the second conductive element when the rotatable arm is positioned to secure the battery module in place relative to the base.

    Abstract translation: 用于车辆的电池系统包括具有电耦合在一起的多个单元的电池模块和用于将电池模块电耦合到电池系统中的其他元件的第一导电元件。 电池系统还具有被配置用于将电池模块固定在车辆中的位置的基座。 基座包括用于将基座电连接到第一导电元件的第二导电元件和用于相对于基座将电池模块固定就位的可旋转臂。 第一导电元件构造成当可旋转臂定位成相对于基座将电池模块固定在适当位置时与第二导电元件接触。

    Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy
    13.
    发明授权
    Fluorinated photosensitizers related to chlorins and bacteriochlorins for photodynamic therapy 有权
    与二氢卟酚和细菌毒素相关的氟光敏剂用于光动力疗法

    公开(公告)号：US07166719B2

    公开(公告)日：2007-01-23

    申请号：US10607922

    申请日：2003-06-27

    Applicant: Ravindra K. Pandey ,  William R. Potter ,  Thomas J. Dougherty

    Inventor： Ravindra K. Pandey ,  William R. Potter ,  Thomas J. Dougherty

    IPC: C09B47/04

    CPC classification number: C07D471/22 ,  A61K41/0071 ,  A61K41/0076 ,  C09B47/00 ,  C09B69/108

    Abstract: Provided herein are compounds for detection, diagnosis and treatment of target tissues or target compositions, including hyperproliferative tissues such as tumors, using photodynamic methods. In particular, photosensitizer compounds that collect in hyperproliferative tissue are provided. In another embodiment, compounds that absorb light at a wavelength of from about 700 to about 850 nm are provided. In a further embodiment, compounds that are detectable by magnetic resonance imaging are provided.

    Abstract translation: 本文提供了使用光动力学方法检测，诊断和治疗靶组织或靶组合物的化合物，包括过度增殖组织如肿瘤。 特别地，提供了在过度增殖组织中收集的光敏剂化合物。 在另一个实施方案中，提供了吸收波长为约700至约850nm的光的化合物。 在另一个实施方案中，提供了可通过磁共振成像检测的化合物。

    Pyropheophorbides and their use in photodynamic therapy
    15.
    再颁专利
    Pyropheophorbides and their use in photodynamic therapy 有权
    偏焦异构体及其在光动力疗法中的应用

    公开(公告)号：USRE39094E1

    公开(公告)日：2006-05-09

    申请号：US10384895

    申请日：2003-03-07

    Applicant: Ravindra K. Pandey ,  Thomas J. Dougherty

    Inventor： Ravindra K. Pandey ,  Thomas J. Dougherty

    IPC: A61K31/409 ,  C07D487/22

    CPC classification number: A61K51/0485 ,  A61K41/0071 ,  A61K2123/00 ,  C07D487/22 ,  C07D519/00

    Abstract: Pyropheophorbide compounds are injected into a host and accumulate in tumor tissue to a higher degree than surrounding normal tissues. When the pyropheophorbide compounds are exposed to a particular wavelength of light the compounds become cytotoxic and destroy the tumor or diseased tissue without causing irreversible normal tissue damage. The pyropheophorbide compounds have shown improved results as compared to drugs currently used in photodynamic therapy. Further, they absorb light further in the red, optimizing tissue penetration mad are retained in the skin for short time periods relative to other drugs used in photodynamic therapy.

    Abstract translation: 将焦磷偏磷酸酯化合物注射到宿主中并在肿瘤组织中积聚到比周围正常组织更高的程度。 当焦偏磷酸酯化合物暴露于特定波长的光时，化合物变成细胞毒性并破坏肿瘤或患病组织而不引起不可逆的正常组织损伤。 与目前在光动力疗法中使用的药物相比，焦偏镁离子化合物显示出改善的结果。 此外，它们进一步吸收红色的光线，相对于光动力治疗中使用的其他药物，优化组织穿透时间短于皮肤的时间。

    Battery monitoring system
    16.
    发明授权
    Battery monitoring system 有权
    电池监控系统

    公开(公告)号：US06727708B1

    公开(公告)日：2004-04-27

    申请号：US10313983

    申请日：2002-12-06

    Applicant: Thomas J. Dougherty ,  William J. Wruck ,  Ronald C. Miles ,  Deeyu C. Chen ,  Michael L. Thompson

    Inventor： Thomas J. Dougherty ,  William J. Wruck ,  Ronald C. Miles ,  Deeyu C. Chen ,  Michael L. Thompson

    IPC: H02J700

    CPC classification number: H01M10/4257 ,  B60L11/14 ,  B60L11/1857 ,  B60L11/1861 ,  B60L2240/545 ,  B60L2240/547 ,  B60L2240/549 ,  B60L2240/80 ,  G01R31/36 ,  H01M10/44 ,  H02J7/0047 ,  Y02T10/70 ,  Y02T10/7005 ,  Y02T10/7044 ,  Y02T10/705 ,  Y02T10/7077

    Abstract: A battery monitoring system is disclosed. The system comprises a means for acquiring a value representative of a first period of time during which the battery will deliver a sufficient amount of power. The system also comprises a means for measuring a set of parameters comprising a voltage of the battery and a temperature of the battery during a second period of time. The system also comprises a means for predicting whether the battery will deliver the sufficient amount of power during a third period of time less than the first period of time. An output signal is provided if the means for predicting determines that the battery will deliver the sufficient amount of power during the third period of time. A system for determining whether a battery for a vehicle will deliver a sufficient amount of power for a sufficient amount of time is also disclosed.

    Abstract translation: 公开了一种电池监视系统。 该系统包括用于获取代表电池将传送足够量的电力的第一时间段的值的装置。 该系统还包括用于在第二时间段内测量包括电池的电压和电池的温度的一组参数的装置。 该系统还包括用于预测在比第一时间段少的第三时间段内电池是否将传递足够量的电力的装置。 如果用于预测的装置确定电池将在第三时间段期间输送足够量的电力，则提供输出信号。 还公开了一种用于确定车辆的电池是否将足够的时间量传递足够的电力的系统。

    Synthesis of isoimide of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer
    20.
    发明授权
    Synthesis of isoimide of chlorins and bacteriochlorins and their use for diagnosis and treatment of cancer 失效
    二氢卟酚和细菌二氢卟酚的异构酰亚胺的合成及其在癌症诊断和治疗中的应用

    公开(公告)号：US5864035A

    公开(公告)日：1999-01-26

    申请号：US812029

    申请日：1997-03-06

    Applicant: Ravindra K. Pandey ,  Andrei N. Kozyrev ,  Thomas J. Dougherty

    Inventor： Ravindra K. Pandey ,  Andrei N. Kozyrev ,  Thomas J. Dougherty

    IPC: A61K41/00 ,  C07D471/22 ,  C07D491/22 ,  C07D487/22

    CPC classification number: C07D471/22 ,  A61K41/0071 ,  C07D491/22

    Abstract: Compounds having utility as light absorbing compounds, especially in the area of photodynamic therapy. Such compounds have the formula: ##STR1## where z is .dbd.O or NR.sub.14 ; R.sub.14 is alkyl or substituted alkyl; R.sub.1 is an amino acid group, a polyamine group, a polyether group or OR.sub.13 where R.sub.13 is alkyl; R.sub.4 through R.sub.11 are --H, --OH alkyl, alkoxy, alkenyl, alkylene, aryl, or aryloxy, or a carbonyl containing group, wherein carbon containing groups may be substituted with carbonyl, hydroxy, phosphoro, carboxy, halo, sulfo, amino and ether substituents, provided that; R.sub.4 may be taken together with R.sub.7 to form .dbd.O; R.sub.8 may be taken together with R.sub.9 to form .dbd.O; R.sub.10 may be taken together with R.sub.11 to form .dbd.O; and R.sub.4 and R.sub.7 may together form a chemical bond and R.sub.8 and R.sub.11 may together form a chemical bond; and R.sub.12 is hydrogen or lower alkyl; provided that if one z is O, the other z is --NR.sub.14.

    Abstract translation: 具有作为光吸收化合物用途的化合物，特别是在光动力疗法领域。 这些化合物具有下式：其中z为= O或NR14; R14是烷基或取代的烷基; R1是氨基酸基团，多胺基团，聚醚基团或OR13，其中R13是烷基; R4至R11是-H，-OH烷基，烷氧基，烯基，亚烷基，芳基或芳氧基或含羰基，其中含碳基团可以被羰基，羟基，磷酰基，羧基，卤素，磺基，氨基和 醚取代基，条件是 R4可以与R7一起形成= O; R8可以与R9一起形成= O; R10可以与R11一起形成= O; 并且R 4和R 7可以一起形成化学键，并且R 8和R 11可以一起形成化学键; 和R 12是氢或低级烷基; 条件是如果一个z是O，另一个Z是-NR 14。

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