公开(公告)号：US4105804A

公开(公告)日：1978-08-08

申请号：US668528

申请日：1976-03-19

申请人： Gyozo Terui ,  Nobuo Takada ,  Shuzo Sawada

发明人： Gyozo Terui ,  Nobuo Takada ,  Shuzo Sawada

IPC分类号： A23J3/00 ,  A23J3/10 ,  C12N1/02 ,  A23J1/00

CPC分类号： A23J3/00 ,  A23J3/10 ,  C12N1/02 ,  Y10S435/828 ,  Y10S435/834 ,  Y10S435/839 ,  Y10S435/849 ,  Y10S435/86 ,  Y10S435/881

摘要： Bacterial cells are separated from a culture broth by adding thereto a solution of casein or alkali-soluble soybean proteins, said culture broth being maintained at a pH less than 6. Bacteria cells are flocculated to form a protein-bacteria co-precipitate which is easily separable by a conventional procedure. The co-precipitate may be directly put to uses such as for foods or feeds.

摘要翻译： 通过向其中加入酪蛋白或碱溶性大豆蛋白溶液，从培养液中分离出细菌细胞，所述培养液维持在小于6的pH值。细菌细胞被絮凝形成蛋白质 - 细菌共沉淀物，其容易 可以通过常规方法分离。 共沉淀物可以直接用于食品或饲料。

公开(公告)号：US4064009A

公开(公告)日：1977-12-20

申请号：US694512

申请日：1976-06-09

申请人： David S. Fukuda ,  Bernard J. Abbott ,  Robert A. Archer

发明人： David S. Fukuda ,  Bernard J. Abbott ,  Robert A. Archer

IPC分类号： A61K31/35 ,  A61K31/352 ,  A61P25/04 ,  C07D311/80 ,  C12P17/06 ,  C07B29/02

CPC分类号： C12P17/06 ,  C07D311/80 ,  Y10S435/822 ,  Y10S435/834 ,  Y10S435/886 ,  Y10S435/931

摘要： 1-Hydroxy-9-keto-3-alkyl-dibenzo[b,d]pyrans or 1,9-dihydroxy-3-alkyl-dibenzo[b,d]pyrans are oxygenated on the penultimate carbon of the alkyl side chain by fermentation with a strain of the micro-organism Bacillus cereus.

摘要翻译： 通过发酵将1-羟基-9-酮-3-烷基 - 二苯并[b，d]吡喃或1,9-二羟基-3-烷基 - 二苯并[b，d]吡喃氧化在烷基侧链的倒数第二碳上 具有微生物蜡样芽孢杆菌的菌株。

公开(公告)号：US3992261A

公开(公告)日：1976-11-16

申请号：US538918

申请日：1975-01-06

申请人： Yoshiyuki Takasaki ,  Yoshimasa Takahara

发明人： Yoshiyuki Takasaki ,  Yoshimasa Takahara

IPC分类号： C12P19/22 ,  C12N9/26 ,  C12N9/44 ,  C12R1/07 ,  C13K7/00 ,  C12D13/02 ,  C07G7/02 ,  C12D13/10

CPC分类号： C13K7/00 ,  C12N9/2425 ,  C12N9/2451 ,  C12Y302/01002 ,  C12Y302/01033 ,  Y10S435/832 ,  Y10S435/834

摘要： A microorganism which simultaneously produces .beta.-amylase and dextrin .alpha.-1,6-glucosidase is cultured. By use of the enzymes thus produced, starch is directly hydrolyzed into maltose in a high yield.

摘要翻译： 培养同时产生β-淀粉酶和糊精α-1,6-葡糖苷酶的微生物。 通过使用由此产生的酶，淀粉以高产率直接水解成麦芽糖。

公开(公告)号：US3959081A

公开(公告)日：1976-05-25

申请号：US562068

申请日：1975-03-26

申请人： Samuel Witz ,  Walter H. Hartung

发明人： Samuel Witz ,  Walter H. Hartung

IPC分类号： C12Q1/04 ,  G01N21/76 ,  C12K1/04

CPC分类号： C12Q1/04 ,  G01N21/76 ,  G01N2333/38 ,  Y10S435/808 ,  Y10S435/834 ,  Y10S435/849 ,  Y10S435/881 ,  Y10S435/917

摘要： A method for identifying a heme-containing microorganism species through the addition of luminol and hydrogen peroxide to a suspension of the microorganism species, thus causing a light emission, accompanied by a recording of the build-up and decay of the light emission which provides a characteristic curve indicative of the microorganism species of the suspension.

摘要翻译： 一种通过将鲁米诺和过氧化氢加入到微生物种类的悬浮液中来鉴定含血红素的微生物种类的方法，从而引起发光，同时记录发光的积聚和衰减，其提供了一种 指示悬浮液的微生物种类的特征曲线。

公开(公告)号：US3890436A

公开(公告)日：1975-06-17

申请号：US46143474

申请日：1974-04-15

申请人： SHIONOGI & CO

发明人： SHOJI JUN ICHI ,  MAYAMA MIKAO ,  MATSUURA SHINZO ,  MATSUMOTO KOUICHI ,  WAKISAKA YOSHIHARU

IPC分类号： A01N63/02 ,  A61K35/74 ,  A61P31/04 ,  C07G11/00 ,  C12P1/04 ,  C12P21/00 ,  C12R1/07 ,  A61K27/00

CPC分类号： C07G11/00 ,  Y10S435/834

摘要： A new antibiotic, Gp-3, being useful as a medicament and veterinary drug for inhibiting the growth of gram-positive pathogenic microorganism, and a process for preparing the same, being characterized by cultivating a Gp-3-producing strain of microorganism belonging to the Genus Bacillus in an aqueous nutrient medium under aerobic conditions.

摘要翻译： 一种新的抗生素Gp-3可用作抑制革兰氏阳性致病微生物生长的药物和兽药及其制备方法，其特征在于培养属于Gp-3的微生物属于 在有氧条件下在含水养分培养基中芽孢杆菌属。

公开(公告)号：US3839560A

公开(公告)日：1974-10-01

申请号：US24255072

申请日：1972-04-10

申请人： SHIMI I

发明人： SHIMI I

IPC分类号： A61K38/00 ,  A61K21/00

CPC分类号： A61K35/74 ,  C07G11/00 ,  Y10S435/834 ,  Y10S435/859 ,  Y10S435/862 ,  Y10S435/883 ,  Y10S435/885 ,  Y10S435/887 ,  Y10S435/911 ,  Y10S435/922

摘要： 1. THE SUBSTANCE YEMENIMCYNIN WHICH: 8A) IS EFFECTIVE IN INHIBITING THE GROWTH OF STAPHYLOCOCCUS AUREUS, MICROCOCCUS LYSODIEKTICUS, MICROCOCCUS ROSEUS, BACILLIUS CERIUS, STREPTOCOCCUS PYOGENES, CANDIDA ALBICANS, TRICOPHYTON MENTAGROPHYTES, TRICHOPHYTON ASTEROIDES, MICROSPORUM AUDOUINI, MICROSPORUM CANIS, MICROSPORUM COOKEI, YOSHIDA TUMOR AND SARCOMA 180 IN THE MOUSE, (B) IS SOLUBLE IN CHLOROFORM, ACETONE, ETHYL ACETATE, BUTYL ACETATE, METHYL ALCOHOL, ETHYL ALCOHOL, AND BUTYL ALCOHOL BUT SUBSTANTIALLY INSOLUBLE IN WATER AND PETROLEUM ETHER; THE PURE CRYSTALLINE FORM OF WHICH: 8C) DECOLORIZES POTASSIUM PERMANGANATE, GIVES POSITIVE MILLON AND NITRATION REACTIONS AND NEGATIVE MOLISH, FEHLING, NINHYDRIN, BIURET, SAKAGUCHI, FERRIC CHLORIDE, IODINE, POTASSIUM THIOCYANATE, AND POTASSIUM FERROCYANIDE REACTIONS; (D) GIVES BY HYDOLYSIS THE AMINO ACIDS ARGININE, ASPARTIC ACID, GLUTAMIC ACID, ALANINE, PHENYLALANINE, ABD ISOLEUCINE; 8E) EXHIBITS ULTRAVIOLET ABSORPTION MAXIMA AT 318 MU, 255 MU, AND 232 MU IN WATER, 230 MU AND 314 MU IN ETHANOL OR ACIDIC ETHANOL, 235 MU AND 356 MU IN ALKALINE ETHANOL SOLUTION AS SHOWN IN FIG.1. (F) EXHIBITS CHARACTERISTICS BANDS IN THE INFRARED ABSORPTION SPECTRUM AT 3200, 31000, 2980, 2950, 2890, 1690, 7645, 1500, 1460, 1410, 1360, 1280, 1265, 930 AND 700 CM.1 AS SHOWN IN FIG.2. (G) HAS AN OPTICAL ROTATION OF (A)D20 -368* IN METHANOL; (H) HAS THE FOLLOWING ELEMENTAL ANALYSIS C, 63.7%, H, 5.60%, N, 7.27%; CL, 4.61%; AMD (I) DARKNESS AT 1940C. AND MELTS AT 212-214*C. WHEN HEATED IN A CAPILLARY TUBE.

公开(公告)号：US3687815A

公开(公告)日：1972-08-29

申请号：US3687815D

申请日：1970-01-30

申请人： MONSANTO CO

发明人： SCHARPF LEWIS G JR

IPC分类号： C12N1/00 ,  C12N1/20 ,  C12B1/00

CPC分类号： C12N1/20 ,  C12N1/005 ,  Y10S435/832 ,  Y10S435/834 ,  Y10S435/837 ,  Y10S435/839 ,  Y10S435/842

摘要： THIS INVENTION RELATES TO METHODS AND COMPOSITIONS FOR GERMINATING SPORES OF THE BACILLUS OR CLOSTRIDIUM GENERA UTILIZING A PROTEASE ENZYME AND A PHYSIOLOGICAL GERMINANT.

公开(公告)号：US3687809A

公开(公告)日：1972-08-29

申请号：US3687809D

申请日：1968-08-06

申请人： KYOWA HAKKO KOGYO KK

发明人： NAKAYAMA KIYOSHI ,  HAGINO HIROSHI

IPC分类号： C12P13/08 ,  C12D13/06

CPC分类号： C12P13/08 ,  Y10S435/822 ,  Y10S435/83 ,  Y10S435/832 ,  Y10S435/834 ,  Y10S435/84 ,  Y10S435/843 ,  Y10S435/876 ,  Y10S435/886 ,  Y10S435/89 ,  Y10S435/911

摘要： A PROCESS FOR PRODUCING L-LYSINE BY CULTURING A MICROORGANISM CAPABLE OF PRODUCING L-LYSINE IN AN AQUEOUS NUTRIENT MEDIUM CONTAINING L-ASPARTIC ACID AND AT LEAST A SOURCE OF CARBON AND NITROGEN UNDER AEROBIC CONDITIONS.

公开(公告)号：US20050220778A1

公开(公告)日：2005-10-06

申请号：US11089606

申请日：2005-03-25

申请人： Jimmie Keeton

发明人： Jimmie Keeton

IPC分类号： A01N63/00 ,  A01N63/02 ,  A61K33/00 ,  A61K35/74 ,  A61K35/742 ,  A61K45/06 ,  A61K45/00 ,  C12N1/20

CPC分类号： A61K45/06 ,  A01N63/00 ,  A01N63/02 ,  A61K33/00 ,  A61K35/742 ,  Y10S435/834 ,  A61K2300/00

摘要： A composition and method for reducing the levels of pathogenic bacteria in an aquatic environment. The composition includes isolated Bacillus cereus which are able to reduce a number of well known pathogenic bacterium from aquatic environments.

摘要翻译： 用于降低水生环境中病原菌水平的组合物和方法。 该组合物包括分离的蜡状芽孢杆菌，其能够从水生环境中减少众多众所周知的致病细菌。

公开(公告)号：US6165740A

公开(公告)日：2000-12-26

申请号：US407286

申请日：1999-09-29

申请人： Masakazu Fukuda ,  Junya Inoue ,  Akito Terai ,  Kazuyuki Kanai ,  Kurayoshi Iseki ,  Mayumi Kamo

发明人： Masakazu Fukuda ,  Junya Inoue ,  Akito Terai ,  Kazuyuki Kanai ,  Kurayoshi Iseki ,  Mayumi Kamo

IPC分类号： C12Q1/04 ,  G01N15/14 ,  C12Q1/02 ,  C12Q1/14

CPC分类号： G01N15/14 ,  C12Q1/04 ,  G01N15/1459 ,  G01N2015/1402 ,  G01N2015/1497 ,  Y10S435/832 ,  Y10S435/833 ,  Y10S435/834 ,  Y10S435/835 ,  Y10S435/836 ,  Y10S435/837 ,  Y10S435/838 ,  Y10S435/839 ,  Y10S435/882 ,  Y10S435/885 ,  Y10S435/911

摘要： To reduce the effects of the contaminants in the measurement of microorganisms and the reduction of the time necessary for the measurement. Measurement is performed of the microorganism prior to and following culture, and the difference between the two is found. This prevents errors caused by the effect of contaminants contained in the specimens. Since the measurement of the microorganism is performed by means of a flow cytometer, the microorganisms can be measured even when the culture period is short. Moreover, the measurements are accurate, since the contaminants are not measured. Furthermore, the growth form of the microorganisms can be determined by measuring the changes in the intensity of the light emission over the duration of emission of the forward scattered light detected by means of a flow cytometer. Accordingly, based on differences in the particle-size distribution prior to and following culture, it is possible to formulate five major bacterial classifications: Bacilli, Staphylococci, Streptobacilli, Streptococci and yeast fungi.

摘要翻译： 减少污染物在微生物测量中的影响以及减少测量所需的时间。 培养前后培养微生物进行测定，发现两者之间的差异。 这样可以防止样品中含有污染物的影响引起的错误。 由于通过流式细胞仪进行微生物的测定，所以即使在培养期短的情况下也可以测定微生物。 此外，测量是准确的，因为不测量污染物。 此外，微生物的生长形式可以通过测量通过流式细胞仪检测的前向散射光的发射持续时间内的发光强度的变化来确定。 因此，根据培养之前和之后的粒度分布的差异，可以制定五种主要的细菌分类：芽孢杆菌，葡萄球菌，链球菌，链球菌和酵母真菌。