公开(公告)号：US09192306B2

公开(公告)日：2015-11-24

申请号：US14021933

申请日：2013-09-09

Applicant: STC.UNM

Inventor： Jingkuang Chen

IPC: A61B5/00 ,  A61B5/02 ,  A61B8/12 ,  A61B8/00 ,  A61B8/08

CPC classification number: A61B5/0095 ,  A61B5/0086 ,  A61B5/02007 ,  A61B8/0833 ,  A61B8/12 ,  A61B8/4472 ,  A61B8/4483 ,  A61B8/483 ,  A61B2562/028 ,  Y10T29/49826

Abstract: A photoacoustic medical imaging device may include a substrate, an array of ultrasonic transducers on the substrate, at least one groove etched on the substrate, at least one optical fiber, and at least one facet. Each optical fiber is disposed in one of the grooves. Each facet is etched in one of the grooves and coated with a layer of metal having high infrared reflectivity. Each optical fiber is configured to guide infrared light from a light source through the fiber and toward the respective facet. The facet is configured to reflect the infrared light toward a target.

Abstract translation: 光声医学成像装置可以包括衬底，衬底上的超声换能器阵列，蚀刻在衬底上的至少一个凹槽，至少一个光纤和至少一个面。 每个光纤被布置在一个凹槽中。 每个刻面在一个凹槽中蚀刻并涂覆有具有高红外反射率的金属层。 每个光纤被配置为引导来自光源的红外光通过光纤并朝向相应的刻面。 小面被配置为将红外光反射到目标。

公开(公告)号：US09180443B1

公开(公告)日：2015-11-10

申请号：US14091776

申请日：2013-11-27

Applicant: Alexey Serov ,  Plamen B Atanassov

Inventor： Alexey Serov ,  Plamen B Atanassov

IPC: B01J21/00 ,  B01J23/00 ,  B01J27/00 ,  B01J27/24 ,  B01J37/00 ,  B01J37/08

CPC classification number: B01J23/745 ,  B01J21/08 ,  B01J37/0018 ,  B01J37/0036 ,  B01J37/0063 ,  B01J37/036 ,  B01J37/06 ,  B01J37/082 ,  B01J37/084 ,  B01J37/343 ,  H01M4/9008

Abstract: In the present disclosure, imidazole-derived materials including M-N-C catalysts, imidazole-derived MOFs and MOF-based M-N-C catalysts as well as methods for preparing the same utilizing mechanosynthesis and/or a sacrificial support-based methods are described.

Abstract translation: 在本公开内容中，描述了包括M-N-C催化剂，咪唑衍生的MOF和基于MOF的M-N-C催化剂的咪唑衍生物质以及利用机械合成和/或基于牺牲载体的方法制备其的方法。

公开(公告)号：US09180214B1

公开(公告)日：2015-11-10

申请号：US13447918

申请日：2012-04-16

Applicant: Yubin Miao

Inventor： Yubin Miao

IPC: A61K51/00 ,  A61K36/14 ,  A61K51/08 ,  A61K38/08

CPC classification number: A61K51/088 ,  A61K9/0019 ,  A61K36/14 ,  A61K38/00 ,  A61K38/08 ,  A61K45/06 ,  G01N33/574 ,  G01N33/60

Abstract: The present invention is directed to novel non-invasive diagnostic tools/compounds to image and treat cancers, especially cancers which overexpress GnRH such as breast cancer, prostate cancer and melanoma, among others, including metastatic breast cancer, prostate cancer and/or melanoma among numerous others in vivo. The novel imaging probes are capable of detecting cancerous cells, as well as their metastatic spread in tissues. The novel probes of the present invention will also be useful to initiate therapy for breast and/or prostate cancer, among other cancers, as well as monitor patients' response to chemotherapy treatments and other interventions or therapies used in the treatment of cancer, including metastatic cancer as otherwise described herein. Compounds according to the present invention may be used as diagnostic tools for diagnosing cancer as well as therapeutic agents for treating cancer and related secondary disease states and conditions.

Abstract translation: 本发明涉及用于成像和治疗癌症的新型非侵入性诊断工具/化合物，特别是过度表达GnRH的癌症，例如乳腺癌，前列腺癌和黑素瘤等，包括转移性乳腺癌，前列腺癌和/或黑素瘤 许多其他人在体内。 新型成像探针能够检测癌细胞，以及它们在组织中的转移扩散。 本发明的新型探针也可用于启动乳腺癌和/或前列腺癌以及其他癌症的治疗，以及监测患者对化疗治疗的反应以及用于治疗癌症的其它干预措施或疗法，包括转移性 本文另有描述的癌症。 根据本发明的化合物可用作诊断癌症的诊断工具以及用于治疗癌症和相关的次级疾病状态和病症的治疗剂。

公开(公告)号：US20150318557A1

公开(公告)日：2015-11-05

申请号：US14647466

申请日：2013-11-27

Applicant: Alexey SEROV ,  Plamen B. ATANASSOV

Inventor： Alexey Serov ,  Plamen B Atanassov

IPC: H01M4/86 ,  H01M4/96 ,  H01M4/90

CPC classification number: H01M4/8605 ,  B01J23/74 ,  B01J23/745 ,  B01J37/08 ,  H01M4/8652 ,  H01M4/9008 ,  H01M4/9083 ,  H01M4/96 ,  H01M8/1011 ,  H01M2008/1095

Abstract: A method for preparing M—N—C catalytic material utilizing ball-milling with or without the addition of a sacrificial support.

Abstract translation: 使用或不加入牺牲载体的球磨制备M-N-C催化材料的方法。

公开(公告)号：US20150295248A1

公开(公告)日：2015-10-15

申请号：US14126565

申请日：2012-06-15

Applicant: Alexey Serov ,  Barr Halevi ,  Michael Robson ,  Wendy Patterson ,  Kateryna Artyushkova ,  Plamen B. Atanassov

Inventor： Alexey Serov ,  Barr Halevi ,  Michael Robson ,  Wendy Patterson ,  Kateryna Artyushkova ,  Plamen B. Atanassov

IPC: H01M4/90

CPC classification number: H01M4/9091 ,  H01M4/90 ,  H01M2004/8689 ,  Y02E60/50

Abstract: A method of preparing M-N-C catalysts utilizing a sacrificial support approach and inexpensive and readily available polymer precursors as the source of nitrogen and carbon is disclosed. Exemplary polymer precursors include those that do not form complexes with iron, but which do complex with silica, for example, polyetheleneimine (PEI), Poly(2-ethyl-2-oxazoline), Poly(acrylamide-co-diallyldimethylammonium chloride), Poly(melamine-co-formaldehyde), Poly[[6-[(1,1,3,3-tetramethylbutyl)amino]-s-triazine-2,4-diyl]-[(2,2,6,6-tetramethyl-4-piperidyl)imino]-hexamethylene-[(2,2,6,6-tetramethyl-4-piperidyl)imino] and the like.

Abstract translation: 公开了一种使用牺牲支撑方法制备M-N-C催化剂的方法，并且公开了廉价且容易获得的聚合物前体作为氮和碳的来源。 示例性聚合物前体包括不与铁形成络合物但与二氧化硅络合的那些，例如聚乙烯亚胺（PEI），聚（2-乙基-2-恶唑啉），聚（丙烯酰胺 - 共二烯丙基二甲基氯化铵），聚 （三聚氰胺 - 共 - 甲醛），聚[[6 - [（1,1,3,3-四甲基丁基）氨基] -s-三嗪-2,4-二基] - [（2,2,6,6-四甲基 -4-哌啶基）亚氨基] - 六亚甲基 - [（2,2,6,6-四甲基-4-哌啶基）亚氨基]等。

公开(公告)号：US20150292964A1

公开(公告)日：2015-10-15

申请号：US14434313

申请日：2013-10-07

Applicant: Scott SIBBETT ,  STC.UNM

Inventor： Scott Sibbett

IPC: G01L1/22 ,  G01L1/04

CPC classification number: G01L1/22 ,  B25J13/084 ,  B25J19/02 ,  G01L1/04 ,  G01L1/18 ,  G01L1/205 ,  G01L5/162 ,  G06F3/041 ,  G06F3/0414 ,  G06F3/045

Abstract: A pliable pressure sensitive sensor device and method of making the same is provided. The sensor includes first and second pliable protective layers, which cover sets of conductive fibers that spatially separated by an electrically conductive pliable layer, which deforms in response to a pressure event. The fiber sets form a grid pattern and are in electrical communication with sets of electrical contacts located in predetermined locations along the fibers. In response to a pressure event in proximity to the contact, the pliable layer deforms and increases the amount of surface area in contact with an electrical contact whereby an electrical resistance at an individual electrical contact decreases in response to the pressure event.

Abstract translation: 提供了一种柔韧的压敏传感器装置及其制造方法。 传感器包括第一和第二柔性保护层，其覆盖由导电柔性层空间分隔的导电纤维组，其响应于压力事件而变形。 光纤组形成网格图案，并且与位于沿着光纤的预定位置的电触点组电连通。 响应于接触点处的压力事件，柔性层变形并增加与电接触件接触的表面积的量，由此响应于压力事件，单独电接触处的电阻降低。

公开(公告)号：US09111059B2

公开(公告)日：2015-08-18

申请号：US14069822

申请日：2013-11-01

Applicant: STC.UNM

Inventor： Marios Stephanou Pattichis ,  Yuebing Jiang ,  Daniel Rolando Llamocca Obregon

IPC: G06F9/455 ,  G06F17/50 ,  H03H17/06 ,  H03H17/02

CPC classification number: G06F9/4401 ,  G06F17/5054 ,  G06F2217/08 ,  H03H17/0241 ,  H03H17/0294 ,  H03H17/06 ,  H04N19/625

Abstract: A dynamically reconfigurable framework manages processing applications in order to meet time-varying constraints to select an optimal hardware architecture. The optimal architecture satisfies time-varying constraints including for example, supplied power, required performance, accuracy levels, available bandwidth, and quality of output such as image reconstruction. The process of determining an optimal solution is defined in terms of multi-objective optimization using Pareto-optimal realizations.

Abstract translation: 动态可重构框架管理处理应用程序，以便满足时变约束以选择最佳硬件体系结构。 最优架构满足时变约束，包括例如所提供的功率，所需性能，精度水平，可用带宽以及诸如图像重建的输出质量。 确定最优解的过程是使用帕累托最优实现的多目标优化来定义的。

公开(公告)号：US09106056B1

公开(公告)日：2015-08-11

申请号：US14103587

申请日：2013-12-11

Applicant: Stephen D. Hersee

Inventor： Stephen D. Hersee

IPC: H01S5/34 ,  H01S5/343 ,  H01S5/40 ,  B82Y20/00

CPC classification number: H01S5/34333 ,  B82Y20/00 ,  G02B21/0004 ,  G02B21/06 ,  H01L25/167 ,  H01L27/156 ,  H01L33/18 ,  H01L33/24 ,  H01L2224/11 ,  H01S5/34 ,  H01S5/4025 ,  Y10S977/951

Abstract: According to various embodiments, the present teachings include an array of nanowire devices. The array of nanowire devices comprises a readout integrated circuit (ROIC). An LED array is disposed on the ROIC. The LED array comprises a plurality of LED core-shell structures, with each LED core-shell structure comprising a layered shell enveloping a nanowire core, wherein the layered shell comprises a multi-quantum-well (MQW) active region. The LED array further comprises a p-side electrode enveloping the layered core-shell structure and electrically connecting the ROIC, wherein each p-side electrode has an average thickness ranging from about 100 nm to about 500 nm. A dielectric layer is disposed on the plurality of LED core-shell structures, with each nanowire core disposed through the dielectric to connect with an n-side semiconductor that is situated on the dielectric.

Abstract translation: 根据各种实施例，本教导包括纳米线装置阵列。 纳米线器件阵列包括读出集成电路（ROIC）。 LED阵列设在ROIC上。 LED阵列包括多个LED芯 - 壳结构，每个LED芯 - 壳结构包括包围纳米线芯的分层壳，其中分层壳包括多量子阱（MQW）活性区。 LED阵列还包括包围层叠芯壳结构并电连接ROIC的p侧电极，其中每个p侧电极具有约100nm至约500nm的平均厚度。 介电层设置在多个LED芯 - 壳结构上，其中每个纳米线芯通过电介质设置，以与位于电介质上的n侧半导体连接。

公开(公告)号：US09079219B2

公开(公告)日：2015-07-14

申请号：US12920271

申请日：2009-02-27

Applicant: Jingkuang Chen

Inventor： Jingkuang Chen

IPC: A61B8/00 ,  G02B6/30 ,  A61H1/00 ,  B06B1/02

CPC classification number: B06B1/0292

Abstract: A therapeutic ultrasound device may include a substrate, at least one high power capacitive micromachined ultrasonic transducer, and at least one imager transducer comprising a capacitive micromachined ultrasonic transducer. The at least one high power capacitive micromachined ultrasonic transducer and the imager transducer may be monolithically integrated on the substrate.

Abstract translation: 治疗性超声装置可以包括衬底，至少一个高功率电容微加工超声换能器，以及包括电容微加工超声换能器的至少一个成像器换能器。 至少一个高功率电容微加工超声换能器和成像器换能器可以单片地集成在基底上。

公开(公告)号：US20150147681A1

公开(公告)日：2015-05-28

申请号：US14504718

申请日：2014-10-02

Applicant: Alexey Serov ,  Plamen B. Atanassov

Inventor： Alexey Serov ,  Plamen B. Atanassov

IPC: H01M4/92 ,  H01M4/88

CPC classification number: H01M4/921 ,  H01M4/928

Abstract: A self-supporting porous alloyed metal material and methods for forming the same. The method utilizes a sacrificial support based technique that enables the formation of uniquely shaped voids in the material. The material is suitable for use as an electrocatalyst in a variety of fuel cell and other applications.

Abstract translation: 一种自支撑多孔合金金属材料及其形成方法。 该方法利用基于牺牲支持的技术，其能够在材料中形成独特形状的空隙。 该材料适用于各种燃料电池和其他应用中的电催化剂。