公开(公告)号：US20180104394A1

公开(公告)日：2018-04-19

申请号：US15842274

申请日：2017-12-14

Applicant: KCI Licensing, Inc.

Inventor： Christopher Brian LOCKE ,  Timothy Mark ROBINSON ,  Aidan Marcus TOUT

IPC: A61M1/00 ,  A61F13/00 ,  A61M25/00

Abstract: Systems and methods for a reduced-pressure interface for providing reduced pressure through a sealing member to a distribution manifold includes a housing having a flange portion and a cavity wall portion such that the cavity wall portion forms a cavity having a tissue-facing cavity opening. A conduit port is coupled to the cavity wall and has a conduit aperture, such that the conduit port is adapted to receive a reduced-pressure delivery conduit. An attachment device is coupled to a tissue-facing side of the flange portion of the housing such that the attachment device couples the housing to the sealing member. Additionally, a cutting element is at least temporarily coupled to the housing proximate to the tissue-facing cavity opening such that the cutting element is adapted to form an aperture in the sealing member when the cutting element is driven into the sealing member with a driving force.

公开(公告)号：US20180085489A1

公开(公告)日：2018-03-29

申请号：US15830528

申请日：2017-12-04

Applicant: KCI Licensing, Inc.

Inventor： Douglas Philip HANSON ,  James COURAGE

IPC: A61L26/00 ,  C08G18/32 ,  A61F13/00 ,  A61L15/26 ,  C08G18/08 ,  C08J9/36 ,  C08J9/00 ,  C08G18/84 ,  C08G18/83 ,  C08G18/76

CPC classification number: A61L26/0066 ,  A61F13/00017 ,  A61F13/00063 ,  A61F13/00068 ,  A61F2013/0017 ,  A61K9/12 ,  A61K38/4873 ,  A61K47/34 ,  A61K47/55 ,  A61K47/59 ,  A61K47/60 ,  A61L15/26 ,  A61L15/32 ,  A61L15/38 ,  A61L15/425 ,  A61L15/44 ,  A61L26/0085 ,  A61L2300/254 ,  A61L2300/404 ,  A61L2300/406 ,  C08G18/14 ,  C08G18/3293 ,  C08G18/40 ,  C08G18/6415 ,  C08G18/7621 ,  C08G18/833 ,  C08G18/84 ,  C08G2101/0083 ,  C08J9/00 ,  C08J9/36 ,  C08J2205/05 ,  C08J2207/10 ,  C08J2375/12 ,  C12Y304/22004 ,  C08L75/04

Abstract: The present disclosure provides amine-modified polymer foams, which may be used for wound dressing materials. For example, the modified materials can include a covalently attached molecule comprising free amine groups. Such amine groups can be used, for instance, to conjugate biologically active polypeptides and/or linkers. Methods for using modified polymers are also provided.

公开(公告)号：US09925317B2

公开(公告)日：2018-03-27

申请号：US14750933

申请日：2015-06-25

Applicant: KCI Licensing, Inc.

Inventor： Robert Peyton Wilkes

IPC: A61F13/02 ,  A61M1/00

CPC classification number: A61M1/0088 ,  A61F13/0216 ,  A61F13/0253 ,  A61F13/0263 ,  A61M1/0023

Abstract: A low-profile reduced pressure treatment apparatus and system are provided. The apparatus includes a moldable conduit holder, a conduit through the conduit holder, and a flexible base. The conduit holder has first and second bulkhead surfaces, a convex top surface, and a bottom surface adapted to conform to a tissue contact region adjacent to a tissue site. An end of the conduit is substantially flush with the first bulkhead surface and a longitudinal axis of the conduit is substantially perpendicular to the first and second bulkhead surfaces. The base is connected on a first side to the bottom surface of the conduit holder, and extends beyond the first bulkhead surface to form an overlay zone adjacent the first bulkhead surface. An adhesive is disposed on a second side of the flexible base to secure the flexible base to the tissue contact region.

公开(公告)号：US09905123B2

公开(公告)日：2018-02-27

申请号：US14326260

申请日：2014-07-08

Applicant: KCI Licensing, Inc.

Inventor： Thomas Paul Lawhorn

IPC: A61M1/00 ,  G08B31/00 ,  G08B19/00

CPC classification number: G08B31/00 ,  A61M1/0031 ,  A61M1/0088 ,  A61M2205/14 ,  A61M2205/15 ,  A61M2205/18 ,  G08B19/00

Abstract: A method of distinguishing leak detection and canister disengagement in a reduced pressure treatment system includes monitoring an actual power level and a source pressure of a reduced pressure pump. The actual power level is compared to a target power level, and the source pressure is compared to a first alarm pressure and a second alarm pressure. A leak alarm is indicated when the actual power level is greater than the target power level and the source pressure is greater than the first alarm pressure. A canister disengaged alarm is indicated when the actual power level is greater than the target power level and the source pressure is less than the second alarm pressure.

公开(公告)号：US09895270B2

公开(公告)日：2018-02-20

申请号：US14078140

申请日：2013-11-12

Applicant: KCI Licensing, Inc.

Inventor： Christopher Guy Coward ,  Mark Stephen James Beard ,  Colin John Hall ,  Ian James Hardman ,  Keith Patrick Heaton ,  James Joseph Sealy ,  David George Whyte

IPC: A61F13/00 ,  A61B17/00 ,  A61M1/00

CPC classification number: A61F13/00068 ,  A61B17/0057 ,  A61B2017/00575 ,  A61B2017/00646 ,  A61B2017/00676 ,  A61F13/00025 ,  A61F13/00029 ,  A61F13/00034 ,  A61F13/00038 ,  A61F13/00987 ,  A61M1/0088 ,  A61M1/0092 ,  Y10T29/49 ,  Y10T29/49826 ,  Y10T156/1052 ,  Y10T156/1056 ,  Y10T156/1057 ,  Y10T156/1062 ,  Y10T156/1304

Abstract: A method of manufacturing a reduced-pressure abdominal treatment system for treating an open abdominal cavity of a patient is provided. A reduced-pressure abdominal treatment system has an open-cavity treatment device for providing reduced-pressure treatment to a patient's abdominal cavity; a deep-tissue closure device for applying a closing force on a deep-tissue wound on a patient's fascia; a surface-wound closure subsystem for providing a closing force on a surface wound on the patient's epidermis. The method of manufacturing may also include the step of providing a reduced-pressure supply subsystem.

公开(公告)号：US20180036178A1

公开(公告)日：2018-02-08

申请号：US15788013

申请日：2017-10-19

Applicant: KCI Licensing, Inc.

Inventor： Timothy Mark ROBINSON ,  Christopher Brian LOCKE

IPC: A61F13/02 ,  A61F13/00 ,  A61M1/00

CPC classification number: A61F13/022 ,  A61F13/00068 ,  A61F13/0216 ,  A61F13/0223 ,  A61M1/0088 ,  Y10T156/10

Abstract: A sealing drape may be suitable for use with a reduced-pressure treatment system for treating a tissue site. The sealing drape may have an interior surface adapted for positioning adjacent to a peripheral surface of the tissue site. The sealing drape may include a sealing material and an absorbent material. The sealing material may be hydrophobic and substantially free of hydrophilic components. Further, the sealing material may be positioned between the interior surface of the sealing drape and the absorbent material. The sealing drape may be used with a manifold for positioning at the tissue site, a reduced-pressure interface, and a reduced-pressure source. Methods of manufacture and treatment are also disclosed.

公开(公告)号：US20180028727A1

公开(公告)日：2018-02-01

申请号：US15729446

申请日：2017-10-10

Applicant: KCI Licensing, Inc.

Inventor： Kevin BENDELE ,  Kenneth SMITH

IPC: A61M1/00

CPC classification number: A61M1/0001 ,  A61M1/0052 ,  A61M1/0088 ,  A61M2205/21 ,  A61M2205/7536

Abstract: A liquid-collection canister includes a liquid collection chamber defined by at least one wall and a first and second gas-communication pathway formed within the at least one wall. A first aperture is positioned between the first gas-communication pathway and the liquid collection chamber to allow gaseous communication between the liquid collection chamber and the first gas-communication pathway. A second aperture is positioned between the second gas-communication pathway and the liquid collection chamber to allow gaseous communication between the liquid collection chamber and the second gas-communication pathway. A first and a second liquid-air separator are positioned over the first aperture and the second aperture, respectively, to substantially prevent liquid passing through the first and second apertures.

公开(公告)号：US09872974B2

公开(公告)日：2018-01-23

申请号：US14747894

申请日：2015-06-23

Applicant: KCI Licensing, Inc.

Inventor： Christopher Brian Locke ,  David George Whyte

IPC: A61M5/145 ,  A61M35/00 ,  A61M1/00 ,  A61M5/142 ,  F04B35/04 ,  F04B43/04

CPC classification number: A61M35/00 ,  A61J2205/00 ,  A61M1/0023 ,  A61M1/0058 ,  A61M1/0088 ,  A61M1/009 ,  A61M5/14224 ,  A61M5/14586 ,  A61M2205/12 ,  A61M2205/33 ,  A61M2205/3327 ,  A61M2205/3337 ,  A61M2205/60 ,  A61M2205/6054 ,  A61M2205/6072 ,  F04B35/045 ,  F04B43/0081 ,  F04B43/02 ,  F04B43/04 ,  F04B45/04 ,  F04B45/047

Abstract: Pump cassettes, wound-treatment apparatuses and methods. In some embodiments, a pump cassette comprises: a pump body having a pump chamber, an inlet valve in fluid communication with the pump chamber, and an outlet valve in fluid communication with the pump chamber; a diaphragm coupled to the pump body such that the diaphragm is movable to vary a volume in the pump chamber; and an identifier configured to store one or more properties of the pump cassette such that the identifier is readable by an automated reader to determine the one or more properties. In some embodiments, the pump cassette is configured to be removably coupled to a wound-treatment apparatus having an actuator such that the actuator can be activated to move the diaphragm.

公开(公告)号：US20180008756A1

公开(公告)日：2018-01-11

申请号：US15713390

申请日：2017-09-22

Applicant: KCI Licensing, Inc.

Inventor： David George WHYTE ,  Christopher Brian LOCKE ,  Richard Daniel John COULTHARD

IPC: A61M1/00 ,  A61F13/00 ,  A61F13/02

CPC classification number: A61M1/0088 ,  A61F13/00029 ,  A61F13/00068 ,  A61F13/0206 ,  A61F13/022 ,  A61M1/0096 ,  Y10T156/10 ,  Y10T156/1051

Abstract: Systems, methods, and apparatuses for treating a tissue site with reduced pressure are described. The system includes a manifold configured to be placed adjacent the tissue site, and a sealing member configured to be placed over the tissue site and the manifold. The system also includes a reduced-pressure source fluidly coupled to the manifold through the sealing member. The system further includes a pouch having an upstream layer having a first thickness, a downstream layer having a second thickness, and an absorbent member enclosed between the upstream layer and the downstream layer. The second thickness is greater than the first thickness. The upstream layer may have a hydrophilic side adjacent the absorbent member, and the downstream layer may have a hydrophobic side adjacent the absorbent member.

公开(公告)号：US09833528B2

公开(公告)日：2017-12-05

申请号：US14851178

申请日：2015-09-11

Applicant: KCI Licensing, Inc.

Inventor： Rodolfo M. Alarcon ,  Amy K. McNulty

IPC: A61L2/16 ,  C07K16/12 ,  A61K39/395 ,  C07K14/00 ,  A61K38/48 ,  A61M1/00 ,  A61L29/16 ,  A61K39/40 ,  A61K45/06

CPC classification number: A61L2/16 ,  A61K38/48 ,  A61K39/395 ,  A61K39/40 ,  A61K45/06 ,  A61L29/16 ,  A61L2300/404 ,  A61M1/00 ,  C07K14/001 ,  C07K16/12 ,  Y02A50/475

Abstract: Methods and compositions for the treatment of biofilms and/or the inhibition of biofilm formation. In one embodiment, a biofilm is treated and/or biofilm formation is inhibited by a method comprising contacting a biofilm or a surface with a bifunctional ligand comprising a quorum-sensing-peptide-binding region and a protease-binding region, whereby the biofilm is treated and/or biofilm formation on the surface is inhibited.