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211.
公开(公告)号:US10704160B2
公开(公告)日:2020-07-07
申请号:US15591671
申请日:2017-05-10
Inventor: Franz A. Koeck , Robert J. Nemanich
Abstract: Apparatuses and methods are provided for manufacturing diamond electronic devices. The apparatus includes a base comprising a water-block and a cover that at least partially covers the water-block. The apparatus includes a sample stage disposed on the base. The apparatus further includes a sample holder disposed on the sample stage and configured to accept a diamond substrate. The apparatus includes controlled thermal interfaces between water-block, sample stage, sample holder and diamond substrate.
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212.
公开(公告)号:US20200172951A1
公开(公告)日:2020-06-04
申请号:US16633812
申请日:2018-07-25
Inventor: Nongjian Tao , Karan Syal
IPC: C12Q1/18 , G01N33/543 , G01N15/14 , G06K9/00
Abstract: A method for rapid antibiotic susceptibility testing by tracking sub-micron scale motion of single bacterial cells including obtaining a biological sample from a subject including live bacteria. Different doses of antibiotic are added to a multi-well glass slide and adding portions of the biological sample to the wells. Bacterial cells are tethered onto the surface. The tethered bacterial cells are imaged and tracked. Bacterial sub-micron motion of tethered cells is measured at the different doses. A processor performs statistical analysis on a population of cells for each antibiotic dose to generate an antibiotic dose curve proportional to the motion changes, where the antibiotic dose curve plots data including a decrease in movement over time indicating a proportional effectiveness of an antibiotic applied to a well.
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公开(公告)号:US10660200B2
公开(公告)日:2020-05-19
申请号:US15625924
申请日:2017-06-16
Inventor: Hanqing Jiang , Cheng Lv , Hongyu Yu
IPC: H01L23/538 , H01L23/498 , H05K1/11 , H05K1/02 , H01M2/20 , H05K1/09 , H05K1/14 , H01L23/14
Abstract: The invention provides an electronic device that includes a first functional body, a second functional body, and at least one connection member connecting the first functional body to the second functional body. The at least one connection member has a spiral pattern, and is suspended in air to allow for stretching, flexing or compressing.
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214.
公开(公告)号:US10604501B2
公开(公告)日:2020-03-31
申请号:US16310305
申请日:2017-06-13
Inventor: Arnaud Chevalier , Omar Khdour , Yanmin Zhang , Sidney Hecht
IPC: C07D321/00 , C07D311/06 , C07D311/58 , C07D403/08 , C07D405/04 , C07D413/04 , C07D417/04 , C07D487/14 , C07D493/10 , A61K47/54 , A61K49/00 , G01N33/58
Abstract: The present invention relates to the use of prodrugs susceptible to nitroreductase (NTR) activation. In particular, provided herein are mitochondria-targeting prodrug compounds and probes, including profluore scent near-infrared (NIR) probes and non-fluorescent prodrugs, as well as to methods of using said prodrug compounds and probes for imaging mitochondria and for mitochondria-specific delivery of therapeutic agents.
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公开(公告)号:US10601371B2
公开(公告)日:2020-03-24
申请号:US16097796
申请日:2017-05-05
Applicant: Arizona Board of Regents on behalf of Arizona State University , Richard Arthur Kiehl , Nicholas Rizzo
Inventor: Richard Arthur Kiehl , Nicholas Rizzo
Abstract: An array of magnetic nanoparticle (MNP) spin torque oscillators (STOs) is described. Each STO is comprised of a uniform, chemically synthesized, spherical nanoparticle which couples to current flowing along a surface. The particles are organized into an array by a self-assembly technique with uniform spacing and close proximity to allow strong electrical and magnetic coupling between particles. The coupling of the nanoparticles to the surface current drives the oscillations by spin-torque, and for phase locking and data input. The uniform, spherical shape of the particles allows the oscillations to be achieved at low currents and with low power dissipation. The MNP-STOs may be used as a basis for massively parallel computing, microwave oscillators, or other applications.
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公开(公告)号:US20200083014A1
公开(公告)日:2020-03-12
申请号:US16684521
申请日:2019-11-14
Applicant: Philipp Borchard , Arizona Board of Regents on Behalf Of Arizona State University , TibaRay, Inc
Inventor: William (Bill) Graves , Philipp Borchard , Vinod Bharadwaj , Valery Dolgashev
Abstract: A photoinjector system containing modularly-structured waveguide-mode launcher, which is reversibly connected to the RF gun (containing a tubular construction formed with disattachably-affixed to one another structurally-complementary halves); and a solenoid magnet in operation enclosing such tubular structure in a central hollow. The resulting quality, power, and frequency rate of operation as well as cost of manufacturing and operation of the system are superior as compared with those of a related art system.
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公开(公告)号:US20200074701A1
公开(公告)日:2020-03-05
申请号:US16556135
申请日:2019-08-29
Inventor: Jianming Liang , Nima Tajbakhsh , Jaeyul Shin
Abstract: Detecting a pulmonary embolism (PE) in an image dataset of a blood vessel involves obtaining a volume of interest (VOI) in the blood vessel, generating a plurality of PE candidates within the VOI, generating a set of voxels for each PE candidate, estimating for each PE candidate an orientation of the blood vessel that contains the PE candidate, given the set of voxels for the PE candidate, and generating a visualization of the blood vessel that contains the PE candidate using the estimated orientation of the blood vessel that contains the PE candidate.
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公开(公告)号:US20200074271A1
公开(公告)日:2020-03-05
申请号:US16556130
申请日:2019-08-29
Inventor: Jianming Liang , Zongwei Zhou , Md Mahfuzur Rahman Siddiquee , Nima Tajbakhsh
Abstract: Disclosed are provided systems, methods, and apparatuses for implementing a multi-resolution neural network for use with imaging intensive applications including medical imaging. For example, a system having means to execute a neural network model formed from a plurality of layer blocks including an encoder layer block which precedes a plurality of decoder layer blocks includes: means for associating a resolution value with each of the plurality of layer blocks; means for processing via the encoder layer block a respective layer block input including a down-sampled layer block output processing, via decoder layer blocks, a respective layer block input including an up-sampled layer block output and a layer block output of a previous layer block associated with a prior resolution value of a layer block which precedes the respective decoder layer block; and generating the respective layer block output by summing or concatenating the processed layer block inputs.
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公开(公告)号:US20200071330A1
公开(公告)日:2020-03-05
申请号:US16552585
申请日:2019-08-27
Inventor: Jian Li
IPC: C07D471/14 , C07D471/22 , C09K11/06 , H01L51/00 , C07D493/22 , C07D495/22 , C07D495/14 , C07D471/04
Abstract: Thermally assisted delayed fluorescent materials with triad-type materials for use in full color displays and lighting applications are provided.
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公开(公告)号:US20200063197A1
公开(公告)日:2020-02-27
申请号:US16611799
申请日:2018-05-15
Inventor: Deirdre Meldrum , Shufang Ci , Shih-Hui (Joseph) Chao , Rhett Martineau , Weimin Gao
Abstract: The present disclosure relates to real-time quantification using loop-mediated isothermal amplification, in particular real-time colorimetric reverse transcription quantitative loop-mediated isothermal amplification (RT-qLAMP). In some embodiments, RT-qLAMP is used to diagnose the presence of and also quantitate the amount of Zika virus in a sample.
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