公开(公告)号：USD495946S1

公开(公告)日：2004-09-14

申请号：US29175061

申请日：2003-01-28

Applicant: Daniel Py ,  Julian V. Chan ,  Norbert M. Assion

Designer： Daniel Py ,  Julian V. Chan ,  Norbert M. Assion

公开(公告)号：US06302101B1

公开(公告)日：2001-10-16

申请号：US09460050

申请日：1999-12-14

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61M1100

CPC classification number: B05B11/3066 ,  A61M11/001 ,  A61M11/06 ,  A61M15/0025 ,  A61M15/0026 ,  A61M15/0065 ,  A61M2205/073 ,  A61M2206/16 ,  B05B1/341 ,  B05B1/3436 ,  B05B11/0038 ,  B05B11/00412 ,  B05B11/007 ,  B05B11/0072 ,  B05B11/0075 ,  B05B11/3001 ,  B05B11/3011 ,  B05B11/3074 ,  B05B11/3076 ,  B05B11/3077 ,  B05B11/309 ,  B05B11/3092 ,  B05B11/3095

Abstract: A pump-type dispenser for dispensing predetermined doses of medicament in droplets or in spray form to the nasal area incorporates a rigid vial for medicament, an expandable pouch located within the rigid vial, a nasal screen, a one-way actuation mechanism, a one-way valve mechanism in the nozzle area and a spring element, both the valve mechanism and the spring element being formed as integral portions of the pump body. The nasal screen aligns the dispenser nozzle with the nasal passage and also allows the user to discreetly hide the nasal area from public view. The one-way valve mechanism in the nozzle area ensures a one-way movement of medicament from the dispenser, thereby preserving substantially perfect sterility of the medicament in the dispenser regardless of the environment surrounding the dispenser, without requiring the use of preservatives. The one-way actuation mechanism enables the user to load and dispense a uniform quantity of medicament with a uniform actuation force and speed via a single continuous motion of the actuation mechanism upon application of a very small force on the actuation trigger mechanism by the user. By preventing the pump mechanism from being left in a loaded state for a prolonged period of time, the one-way actuation mechanism prevents the spring element from experiencing the “fatigue” phenomenon. The rigid vial/expandable-pouch combination facilitates improved long term use, as well as uniformity of dosage independent of the pump orientation.

Abstract translation: 用于将液滴或喷雾形式的预定剂量的药剂分配到鼻区域的泵型分配器包括用于药物的刚性小瓶，位于刚性小瓶内的可膨胀袋，鼻屏，单向致动机构，一个 在喷嘴区域中具有一个阀门机构和一个弹簧元件，阀机构和弹簧元件都形成为泵体的整体部分。 鼻屏幕使分配器喷嘴与鼻通道对准，并且还允许使用者谨慎地隐藏鼻部区域以免公众观察。 喷嘴区域中的单向阀机构确保药物从分配器的单向移动，从而在不需要使用防腐剂的情况下，保持药剂在分配器中基本上完美的无菌性，无论分配器周围的环境如何。 单向致动机构使得用户能够通过使用者在致动触发机构上施加非常小的力而经由致动机构的单一连续运动以均匀的致动力和速度来加载和分配均匀量的药物。 通过防止泵机构长时间处于负载状态，单向致动机构防止弹簧元件发生“疲劳”现象。 刚性小瓶/可膨胀袋组合有助于改善长期使用，以及独立于泵取向的剂量均匀性。

公开(公告)号：US6053433A

公开(公告)日：2000-04-25

申请号：US192843

申请日：1998-11-16

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B65D83/14 ,  A61M11/00 ,  B05B1/34 ,  B05B11/00 ,  B05B1/30

CPC classification number: B05B11/007 ,  B05B1/341 ,  B05B1/3436 ,  B05B11/0072 ,  B05B11/0075

Abstract: A nozzle mechanism for generating an aerosol-type liquid discharge is provided, which nozzle mechanism ensures one-way movement of liquid during discharge and also has a substantially zero "dead volume" at the tip of the nozzle. The nozzle mechanism includes a flexible nozzle portion with an outlet and a fluid channel, a rigid shaft received within the flexible nozzle portion, and a rigid housing surrounding the flexible nozzle portion and exposing the outlet. The rigid shaft interfaces the outlet to form a first normally-closed, one-way valve, as well as to define a swirling chamber for collecting the liquid which has been channeled from the liquid reservoir, prior to being discharged via the outlet. The outlet has a tubular wall with thickness that decreases along the elongated axis of symmetry for the outlet toward the tip of the outlet. The fluid channel is circumferentially positioned within the flexible nozzle portion to create swirling action of the liquid delivered to said swirling chamber. Once the pressure on the swirling liquid reaches a threshold pressure sufficient to radially deform the portion of the outlet forming the first normally-closed valve, the liquid in the swirling chamber is discharged through the outlet. The nozzle mechanism is coupled to a flexible body portion which has a substantially tubular shape and a wall thickness which decreases from the bottom of the body portion toward the flexible nozzle portion. The rigid shaft received within the flexible nozzle portions extends down into the flexible body portion so that a second portion of the rigid shaft interfaces the flexible body portion to form a second normally-closed, one-way valve in the fluid communication path between the liquid reservoir and the swirling chamber.

Abstract translation: 提供了一种用于产生气溶胶型液体排出口的喷嘴机构，该喷嘴机构确保了排出期间液体的单向移动，并且在喷嘴的尖端处也具有基本为零的“死体积”。 喷嘴机构包括具有出口和流体通道的柔性喷嘴部分，容纳在柔性喷嘴部分内的刚性轴以及围绕柔性喷嘴部分并暴露出口的刚性壳体。 刚性轴将出口接合以形成第一常闭单向阀，并且在通过出口排出之前，限定用于收集已经从液体储存器引导的液体的旋转室。 出口具有管状壁，其厚度沿着用于出口朝向出口的尖端的细长对称轴线减小。 流体通道周向地定位在柔性喷嘴部分内，以产生输送到所述旋转室的液体的旋转作用。 一旦旋转液体上的压力达到足以使形成第一常闭阀的出口的部分径向变形的阈值压力，则旋转室中的液体通过出口排出。 喷嘴机构联接到柔性主体部分，其具有基本上管状的形状和从主体部分的底部向柔性喷嘴部分减小的壁厚。 容纳在柔性喷嘴部分内的刚性轴向下延伸到柔性主体部分中，使得刚性轴的第二部分接合柔性主体部分，以在液体之间的流体连通路径中形成第二常闭单向阀 水库和旋转室。

公开(公告)号：US6033384A

公开(公告)日：2000-03-07

申请号：US993969

申请日：1997-12-18

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61M31/00 ,  A61F9/00 ,  B05B11/00 ,  A61M5/178

CPC classification number: B05B11/3011 ,  A61F9/0026 ,  B05B11/3076 ,  B05B11/3092 ,  B05B11/3095 ,  A61M11/00

Abstract: A medicament-dispensing system includes a cartridge for housing and actuating an accordion-like vial-dispenser for dispensing a calibrated amount of medicament by means of a single actuation motion which sequentially loads the vial-dispenser and dispenses the loaded medicament. The vial-dispenser has a front bellows portion, a rear bellows portion, an internal piston mechanism, a medicament storage chamber and a dosage cavity. The cartridge has a trigger mechanism which acts in concert with a notched lever and a wedge-shaped arm internally located in the cartridge to sequentially load the dosage cavity with medicament and discharge it. Depression of the trigger mechanism simultaneously extends, by means of the notched lever, the front bellows portion and compresses the rear bellows portion to load the dosage cavity with medicament. Once the notched lever has extended the front bellows portion a predetermined distance, the notched lever is disengaged from the front bellows portion by the wedge-shaped arm extending from the rear wall of the housing, thereby releasing the front and rear bellows portions, along with the internal piston mechanism, to return to original position and force the medicament from the dosage cavity via a nozzle of the vial-dispenser.

公开(公告)号：US5746728A

公开(公告)日：1998-05-05

申请号：US534609

申请日：1995-09-27

Applicant: Daniel Py

Inventor： Daniel Py

IPC: F04B9/14 ,  A61F9/00 ,  B05B11/00 ,  A61M35/00 ,  B65B37/00

CPC classification number: B05B11/307 ,  A61F9/0008 ,  B05B11/0037 ,  B05B11/007 ,  B05B11/0072 ,  B05B11/3001 ,  B05B11/3074 ,  B05B11/3077 ,  B05B11/309

Abstract: A pump for delivering a fluid contained in an elastic phial includes a pump body and a movable piston fitted inside the pump body. The front end of the pump body is located on a fluid-outlet side, and the front end includes an outlet orifice (11) sealed off by an elastic membrane (24). The outlet orifice is connected to a pump duct (18) inside the pump body, and the pump duct 18 is in turn connected to a fluid-inlet orifice (15). An end (2) of the movable piston is hermetically fitted within the pump duct (18) with slight friction, and the displacement of the end (2) of the piston relative to the portion of the pump body between the inlet orifice (15) and the a stop position (16) near the outlet orifice (11) determines the quantity of fluid expelled from the pump body. The inlet orifice allows a predetermined quantity of fluid to be trapped at the end of the pump duct (18) before being expelled through the outlet orifice (11). With the exception of the front end of the pump body, the pump body and the movable piston are totally enveloped by the elastic phial.

Abstract translation: 用于输送包含在弹性药瓶中的流体的泵包括装配在泵体内的泵体和可移动活塞。 泵体的前端位于流体出口侧，前端包括由弹性膜（24）密封的出口孔（11）。 出口孔连接到泵体内部的泵管道（18），并且泵管道18又连接到流体入口孔口（15）。 可移动活塞的端部（2）以轻微的摩擦气密地装配在泵管道（18）内，并且活塞的端部（2）相对于入口孔（15）之间的泵体的部分的位移， 并且在出口孔11附近的停止位置（16）确定从泵体排出的流体的量。 入口孔允许预定量的流体在通过出口孔（11）排出之前被捕获在泵管道（18）的端部。 除了泵体的前端以外，泵体和可动活塞都被弹性球囊完全包住。

公开(公告)号：US5366499A

公开(公告)日：1994-11-22

申请号：US178946

申请日：1994-01-05

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61F2/14

CPC classification number: A61F2/142 ,  A61F2/14

Abstract: A prosthesis for implanting in an eye has a lens member and a double interface member which is coupled to the periphery of the lens member. The double interface member is comprised of a more superficial branch and a deeper branch which project out from the lens member. The double interface member has a plurality of pores for permitting the ingrowth of tissue to anchor the prosthesis to the eye. The double interface member also has an anatomical structure into which eye tissue is inserted, so as to become an immediate anchor to the eye and an immediate barrier to external pathogens.

Abstract translation: 用于植入眼睛的假体具有透镜构件和耦合到透镜构件的周边的双界面构件。 双界面构件由更浅的分支和从透镜构件突出的较深的分支组成。 双界面构件具有多个孔，用于允许组织的向内生长将假体锚定到眼睛。 双界面构件还具有其中插入眼睛组织的解剖结构，以便成为眼睛的立即锚定并且立即对外部病原体的屏障。

公开(公告)号：US4908024A

公开(公告)日：1990-03-13

申请号：US188331

申请日：1988-05-04

Applicant: Daniel Py

Inventor： Daniel Py

IPC: A61F9/00

CPC classification number: A61F9/0008

Abstract: An ocular self-treatment apparatus and self-treatment method for simplifying and improving the ease of ocular self-treatment. The apparatus is formed of a frame to be worn by the patient. The frame supports one or two light deviation apparatus. These apparatus deviate the visual access of the patient. The frame also supports one or two dispensers of ocular treatment material. A patient rotates his eye upwards and the light deviation apparatus allows him to observe the lower ocular area. The patient can then evert his lower eyelid and apply ocular treatment material to the cul-de-suc of the conjunctiva.

Abstract translation: 一种眼部自我治疗装置和自我治疗方法，用于简化和改善眼部自我治疗的容易性。 该装置由要由患者佩戴的框架形成。 框架支撑一个或两个光偏差装置。 这些装置偏离病人的视觉访问。 该框架还支持一个或两个眼部治疗材料分配器。 患者向上旋转眼睛，光偏差装置允许他观察较低的眼部区域。 然后，患者可以将其下眼皮转移，并将眼部治疗材料应用于结膜的死亡。

公开(公告)号：US09989177B2

公开(公告)日：2018-06-05

申请号：US13874839

申请日：2013-05-01

Applicant: Daniel Py

Inventor： Daniel Py

IPC: F16K31/44 ,  F16L29/02 ,  B65B39/00 ,  B65B3/00 ,  A61M39/26 ,  A61M39/18

CPC classification number: F16L29/02 ,  A61M39/18 ,  A61M39/26 ,  A61M2039/268 ,  B65B3/003 ,  B65B39/001

Abstract: A valve comprises a shell, a flexible valve member sealingly mounted within the shell, and a valve body mounted atop the flexible valve member within the shell. The flexible member is moveable between closed and open positions to allow the flow of fluid therethrough. The valve is engageable with a filling device having flow ports and a surrounding closure. The closure and/or the shaft is movable between (i) a first position wherein the closure closes the port(s), and (ii) a second position opening the port(s). Alternatively, the valve may comprise a portion of a female connector and the filling device may comprise a portion of a male connector to form an aseptic fluid connector for the aseptic transfer of fluid therethrough.

公开(公告)号：US09408455B2

公开(公告)日：2016-08-09

申请号：US12701194

申请日：2010-02-05

Applicant: Daniel Py

Inventor： Daniel Py

IPC: B67B7/00 ,  B65D5/72 ,  B65D25/40 ,  B65D35/38 ,  F16K31/00 ,  A45D40/26 ,  B65D35/06 ,  B65D35/08 ,  B65D47/20 ,  B65D83/00

CPC classification number: B65D47/205 ,  A45D40/26 ,  B65D35/06 ,  B65D35/08 ,  B65D35/38 ,  B65D83/0055

Abstract: A device and method for aseptically storing and dispensing a liquid. The device has container forming a variable-volume storage chamber, and a one-way valve coupled in fluid communication with the storage chamber and having an elastic valve member forming a normally closed valve opening. The valve member is movable between a normally closed position, and an open position with at least a segment of the elastic valve member spaced radially away from the closed position to allow the passage of fluid from the storage chamber through the valve opening. The liquid is maintained hermetically sealed in the storage chamber with respect to ambient atmosphere throughout dispensing multiple portions of the liquid from the storage chamber through the one-way valve.

Abstract translation: 一种用于无菌储存和分配液体的装置和方法。 该装置具有形成可变容积储存室的容器和与存储室流体连通并具有形成常闭阀开口的弹性阀构件的单向阀。 阀构件可在正常关闭位置和打开位置之间移动，其中弹性阀构件的至少一段与径向远离关闭位置间隔开，以允许流体从储存室通过阀门开口。 液体相对于环境气氛保持密封在储存室中，通过单向阀从储存室分配多个液体部分。

公开(公告)号：US09051064B2

公开(公告)日：2015-06-09

申请号：US12789565

申请日：2010-05-28

Applicant: Daniel Py ,  Norbert M. Assion

Inventor： Daniel Py ,  Norbert M. Assion

IPC: B65B1/04 ,  B65B3/00 ,  A61J1/14 ,  A61J1/18 ,  B65B7/16 ,  B65D51/00 ,  A61J1/20

CPC classification number: B65B3/003 ,  A61J1/1406 ,  A61J1/1412 ,  A61J1/1425 ,  A61J1/1431 ,  A61J1/1468 ,  A61J1/18 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2055 ,  A61J1/2075 ,  A61J1/2096 ,  A61M2207/00 ,  A61M2209/045 ,  B65B3/027 ,  B65B7/161 ,  B65B51/10 ,  B65B55/08 ,  B65B2039/009 ,  B65D51/002

Abstract: Disclosed is a uniquely configured medicament vial assembly which includes a storage vial, a stopper member and a securing ring. The vial assembly is configured to improve healthcare worker safety by providing a shielded gripping location to aid in the reduction of accidental needle sticks. The storage vial has a body portion which defines an interior chamber for storing a predetermined medicament and a neck portion through which medicament is received into and withdrawn from the interior chamber. The stopper member is inserted into the mouth of the vial and establishes a first seal. The securing ring is engaged with the mouth of the vial and adapted and configured for retaining the stopper member within the vial mouth and effectuating a second seal. The securing ring is formed from a thermoplastic and/or elastic material. Preferably, the securing ring is formed by molding the thermoplastic and/or elastic material over a portion of the storage vial and stopper member when engaged within the vial mouth.

Abstract translation: 公开了一种独特构造的药物小瓶组件，其包括存储小瓶，止动构件和固定环。 小瓶组件被配置成通过提供屏蔽夹持位置来帮助减少意外的针棒来改善医护人员的安全性。 存储小瓶具有主体部分，其限定用于存储预定药物的内部腔室和颈部部分，药物通过所述颈部部分容纳到内部腔室中并从内部腔室中排出。 止动件插入小瓶的口中并建立第一密封。 固定环与小瓶的口接合并适于和构造成将止动件保持在小瓶口内并实现第二密封。 固定环由热塑性和/或弹性材料形成。 优选地，固定环通过在接合在小瓶口中时将热塑性和/或弹性材料模制在存储小瓶和止动构件的一部分上而形成。