TRAJECTORY EVALUATION METHOD AND APPARATUS
    251.
    发明公开

    公开(公告)号:US20240151554A1

    公开(公告)日:2024-05-09

    申请号:US18500041

    申请日:2023-11-01

    CPC classification number: G01C23/00

    Abstract: The present disclosure provides a method and an apparatus for quickly and accurately evaluating a trajectory of a projectile such as a satellite launching rocket or a missile by comparing the trajectory with a reference trajectory. The trajectory evaluation method includes: acquiring time series positioning data for a target and predetermined reference trajectory information; and mapping points representing the time series positioning data on a graph into corresponding points on a reference trajectory representing the predetermined reference trajectory information while relocating each mapped point onto a relocatable section taking into account a movable range dependent on a speed of the target, and determining a maximum value of distances moved by the points while the points are mapped and relocated as a similarity between the time series positioning data and the reference trajectory.

    Apparatus and Methods for Analysis of Gene Mutation

    公开(公告)号:US20240117442A1

    公开(公告)日:2024-04-11

    申请号:US18490116

    申请日:2023-10-19

    CPC classification number: C12Q1/6886 C12Q2600/156 C12Q2600/166

    Abstract: Methods and apparatuses are disclosed for detecting a presence of a mismatched pair in an oligonucleotide duplex that is attached to a solid substrate using an atomic force microscope. In particular, methods and apparatuses of the invention allow qualitative and quantitative analysis of the presence of a mismatched pair in a sample of oligonucleotide duplex using an atomic force microscope comprising an AFM cantilever that includes a DNA mismatch repair protein. Methods and apparatuses of the invention allow detection of gene mutation without a need for amplification, labeling, or modification of the sample. Such apparatuses and methods can be used in a wide variety of clinical diagnostic applications including detection and/or analysis of biomarkers related to, but not limited to, cancer, trauma, sepsis, aseptic inflammation, myocardial infarction, stroke, transplantation, diabetes, sickle cell disease, as well as other clinical conditions.

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