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    Transition metal complexes with bidentate ligand having an imidazole ring
    21.
    发明授权
    Transition metal complexes with bidentate ligand having an imidazole ring 有权
    与具有咪唑环的二齿配体的过渡金属络合物

    公开(公告)号：US07090756B2

    公开(公告)日：2006-08-15

    申请号：US10639181

    申请日：2003-08-11

    申请人： Fei Mao ,  Adam Heller

    发明人： Fei Mao ,  Adam Heller

    IPC分类号： C12M1/00

    CPC分类号： A61B5/1486 ,  A61B5/14532 ,  A61B5/1477 ,  C07F9/005 ,  C07F15/0026 ,  C07F15/0053 ,  C07F15/025 ,  C07F15/065 ,  C08F8/42 ,  C08F8/44 ,  C09B57/10 ,  C12Q1/004

    摘要： Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme based electrochemical sensors. In such instances, transition metal complexes accept electrons from, or transfer electrons to, enzymes at a high rate and also exchange electrons rapidly with the sensor. The transition metal complexes include at least one substituted or unsubstituted biimidazole ligand and may further include a second substituted or unsubstituted biimidazole ligand or a substituted or unsubstituted bipyridine or pyridylimidazole ligand. Transition metal complexes attached to polymeric backbones are also described.

    摘要翻译： 描述了铁，钴，钌，锇和钒的新型过渡金属络合物。 过渡金属络合物可用作酶基电化学传感器中的氧化还原介质。 在这种情况下，过渡金属配合物以高速率接受电子或将电子转移到酶，并且还与传感器快速交换电子。 过渡金属络合物包括至少一个取代或未取代的双咪唑配体，并且还可以包括第二取代或未取代的双咪唑配体或取代或未取代的联吡啶或吡啶基咪唑配体。 还描述了连接到聚合物主链上的过渡金属络合物。

    Method and apparatus for providing EMC Class-B compliant RF transmitter for data monitoring an detection systems
    22.
    发明申请
    Method and apparatus for providing EMC Class-B compliant RF transmitter for data monitoring an detection systems 审中-公开
    用于提供符合EMC Class-B标准的射频发射器，用于数据监测检测系统的方法和设备

    公开(公告)号：US20060166629A1

    公开(公告)日：2006-07-27

    申请号：US11041566

    申请日：2005-01-24

    申请人： Christopher Reggiardo

    发明人： Christopher Reggiardo

    IPC分类号： H04B1/04 ,  H01Q11/12

    CPC分类号： A61B5/14532 ,  A61B5/0002 ,  A61B2560/0271 ,  H04W52/367 ,  H04W80/00 ,  H04W84/18

    摘要： Method and apparatus for providing EMC Class-B compliant RF transmission for a data monitoring and detection system having a sensor for detecting one or more glucose levels, a transmitter configured to transmit a respective signal corresponding to each of the detected glucose levels using a data transmission protocol including wireless data transmission protocols, to a receiver which is configured to receive the transmitted signals corresponding to the detected glucose levels is provided. When placed in an EMC Class-B compliant mode the monitoring and detection system along with any associated patient treatment units would be allowed to operate in hospital environments and on commercial aircraft during flight.

    摘要翻译： 用于为具有用于检测一个或多个葡萄糖水平的传感器的数据监测和检测系统提供符合EMC Class-B标准的RF传输的方法和装置，发射机被配置为使用数据传输来发送对应于每个检测到的葡萄糖水平的相应信号 提供了包括无线数据传输协议的协议，被配置为接收与检测到的葡萄糖水平相对应的发送信号的接收机。 当符合EMC Class-B标准的模式时，监控和检测系统以及任何相关的患者治疗单元将被允许在飞行期间在医院环境和商用飞机上运行。

    Subcutaneous glucose electrode
    24.
    发明申请
    Subcutaneous glucose electrode 失效
    皮下葡萄糖电极

    公开(公告)号：US20060003398A1

    公开(公告)日：2006-01-05

    申请号：US11182634

    申请日：2005-07-15

    申请人： Adam Heller ,  Michael Pishko

    发明人： Adam Heller ,  Michael Pishko

    IPC分类号： C12Q1/54 ,  C12M3/00

    CPC分类号： C12Q1/54 ,  C12Q1/006 ,  Y10S435/817 ,  Y10S435/917 ,  Y10S435/962

    摘要： A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species of serum or blood. The electrode is preferably layered, with the layers serially deposited within a recess upon the tip of a polyamide insulated gold wire. A first glucose concentration-to-current transducing layer can be overcoated with an electrically insulating and glucose flux limiting layer (second layer) on which, optionally, an immobilized interference-eliminating horseradish peroxidase based film is deposited. An outer layer is preferably biocompatible.

    摘要翻译： 描述了设计用于皮下体内电导率监测葡萄糖的小直径柔性电极。 电极被设计成允许“一点”体内校准，即即使在血清或血液的其它电反应物质的存在下也能在零葡萄糖浓度下具有零输出电流。 电极优选是层叠的，其中层被串联地沉积在聚酰胺绝缘金线的尖端上的凹部内。 可以用电绝缘和葡萄糖通量限制层（第二层）涂覆第一葡萄糖浓度 - 电流转导层，其上任选地沉积固定的干扰消除辣根过氧化物酶膜。 外层优选是生物相容的。