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28 条记录 (耗时 0.026 秒)

    Flow cells for electron microscope imaging with multiple flow streams
    21.
    发明授权
    Flow cells for electron microscope imaging with multiple flow streams 有权
    流动池用于具有多个流动流的电子显微镜成像

    公开(公告)号：US09196457B2

    公开(公告)日：2015-11-24

    申请号：US13478413

    申请日：2012-05-23

    申请人： Joseph M Grogan ,  Haim H Bau

    发明人： Joseph M Grogan ,  Haim H Bau

    IPC分类号： H01J37/20 ,  H01J37/28

    CPC分类号： H01J37/28 ,  H01J37/20 ,  H01J2237/2003 ,  Y10T156/10 ,  Y10T156/1052

    摘要： Provided are flow cell devices—referred to as nanoaquariums—that are microfabricated devices featuring a sample chamber having a controllable height in the range of nanometers to micrometers. The cells are sealed so as to withstand the vacuum environment of an electron microscope without fluid loss. The cells allow for the concurrent flow of multiple sample streams and may be equipped with electrodes, heaters, and thermistors for measurement and other analysis devices.

    摘要翻译： 提供了称为纳米水族箱的流动池装置，其是具有可调高度在纳米至微米范围内的样品室的微制造装置。 电池密封，以承受电子显微镜的真空环境而无流体损失。 电池允许多个样品流的同时流动，并且可以配备用于测量和其它分析装置的电极，加热器和热敏电阻。

    Multiple-electrode and metal-coated probes
    24.
    发明授权
    Multiple-electrode and metal-coated probes 有权
    多电极和金属涂层探针

    公开(公告)号：US08702927B2

    公开(公告)日：2014-04-22

    申请号：US13263234

    申请日：2010-04-23

    申请人： Haim H. Bau ,  Michael G. Schrlau ,  Rui Zhang

    发明人： Haim H. Bau ,  Michael G. Schrlau ,  Rui Zhang

    IPC分类号： G01N27/26 ,  C12M1/42 ,  C12M1/34

    CPC分类号： G01N33/48728

    摘要： Provided are probes featuring multiple electrodes, which probes have diameters in the nanometer range and may be inserted into cells or other subjects so as to monitor an electrical characteristic of the subject. The probes may also include a conductive coating on at least one probe element to improve the probes' performance. The probes may also be used to inject a fluid or other agent into the subject and simultaneously monitor changes in the subject's electrical characteristics in response to the injection. Related methods of fabricating and of using the inventive probes are also provided.

    摘要翻译： 提供了具有多个电极的探针，其探针具有纳米范围的直径并且可以插入细胞或其他受试者中，以便监测受试者的电特性。 探针还可以包括至少一个探针元件上的导电涂层以改善探针的性能。 探针还可以用于将流体或其它试剂注射到受试者中并且同时监测受试者响应于注射的电特征的变化。 还提供了制造和使用本发明的探针的相关方法。

    MULTIPLE-ELECTRODE AND METAL-COATED PROBES
    26.
    发明申请
    MULTIPLE-ELECTRODE AND METAL-COATED PROBES 有权
    多电极和金属涂层探针

    公开(公告)号：US20120282644A1

    公开(公告)日：2012-11-08

    申请号：US13263234

    申请日：2010-04-23

    申请人： Haim H. Bau ,  Michael G. Schrlau ,  Rui Zhang

    发明人： Haim H. Bau ,  Michael G. Schrlau ,  Rui Zhang

    IPC分类号： C12M1/34 ,  B44C1/22 ,  G01N27/26 ,  B05D5/12

    CPC分类号： G01N33/48728

    摘要： Provided are probes featuring multiple electrodes, which probes have diameters in the nanometer range and may be inserted into cells or other subjects so as to monitor an electrical characteristic of the subject. The probes may also include a conductive coating on at least one probe element to improve the probes' performance. The probes may also be used to inject a fluid or other agent into the subject and simultaneously monitor changes in the subject's electrical characteristics in response to the injection. Related methods of fabricating and of using the inventive probes are also provided.

    摘要翻译： 提供了具有多个电极的探针，其探针具有纳米范围的直径并且可以插入细胞或其他受试者中，以便监测受试者的电特性。 探针还可以包括至少一个探针元件上的导电涂层以改善探针的性能。 探针还可以用于将流体或其它试剂注射到受试者中并且同时监测受试者响应于注射的电特征的变化。 还提供了制造和使用本发明的探针的相关方法。

    Nanotube-based sensors and probes
    28.
    发明授权
    Nanotube-based sensors and probes 有权
    基于纳米管的传感器和探头

    公开(公告)号：US07964159B2

    公开(公告)日：2011-06-21

    申请号：US11177111

    申请日：2005-07-08

    申请人： Haim H. Bau ,  Byong Man Kim ,  Michael A. Riegelman ,  Yury Gogotsi

    发明人： Haim H. Bau ,  Byong Man Kim ,  Michael A. Riegelman ,  Yury Gogotsi

    IPC分类号： G01N21/01 ,  G01N21/75 ,  G01N33/48

    CPC分类号： G01N33/54373 ,  B82Y15/00 ,  B82Y20/00 ,  G02B21/34 ,  Y10S977/92 ,  Y10S977/924

    摘要： Described herein are novel devices for the study of transport characteristics of complex or simple fluids, interactions among molecules in suspension, interactions between molecules in suspension and wall-bound molecules, and biochemical sensing devices made of reservoirs for fluid containment linked by a nanotubes. Also disclosed are methods of delivering medicaments and monitoring fluidic interactions of molecules or analytes.

    摘要翻译： 本文描述了用于研究复杂或简单流体的运输特性，悬浮分子之间的相互作用，悬浮液中的分子与壁结合分子之间的相互作用以及由用于通过纳米管连接的用于流体容纳的储存器的生化传感装置的新型装置。 还公开了递送药物和监测分子或分析物的流体相互作用的方法。