Abstract:
Cephalad and caudal vertebral facet joint prostheses and methods of use are provided. The prostheses provide an artificial facet joint structure including an artificial articular configuration unlike the preexisting articular configuration. The radii and material stress values of the prostheses are configured to sustain contact stress. The cephalad prosthesis provides for posterior-anterior adjustment. Both prostheses permit lateral adjustment and adjustment to accomodate interpedicle distance. Further, the prostheses may be customized to provide a pre-defined lordotic angle and a pre-defined pedicle entry angle.
Abstract:
A chemical compound of formula (I) wherein R1 and R2 are independently selected from hydrogen and alkyl; R3 is alkyl; R4 and R5 are selected from hydrogen and alkyl; R6 and R7 are independently selected from hydrogen, halogen, hydroxyl, alkyl, aryl, amino, alkylamino, dialkylamino, alkoxy, aryloxy, alkylthio, alkylsulfoxyl, nitro, carbonitrile, carbo-alkoxy, carbo-aryloxy and carboxyl; and A is a 5- or 6-membered ring optionally containing one or more heteroatoms wherein the atoms of the ring A, other than the unsaturated carbon atoms of the phenyl ring to which the ring A is fused, are saturated or unsaturated, and pharmaceutically acceptable salts, addition compounds and prodrugs thereof; and the use thereof in therapy, particularly as an agonist or antagonist of a 5HT receptor, particularly a 5HT2C receptor, for instance in the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes insipidus, and sleep apnea, and particularly for the treatment of obesity.
Abstract translation:式(I)的化合物,其中R 1和R 2各自独立地选自氢和烷基; R 3是烷基; R 4和R 5选自氢和烷基; R 6和R 7独立地选自氢,卤素,羟基,烷基,芳基,氨基,烷基氨基,二烷基氨基,烷氧基,芳氧基,烷硫基,烷基亚砜基,硝基,腈 ,碳 - 烷氧基,碳 - 芳氧基和羧基; 并且A是任选地含有一个或多个杂原子的5-或6-元环,其中除了环A稠合的苯环的不饱和碳原子之外的环A的原子是饱和或不饱和的, 可接受的盐,加成化合物和前药; 以及其在治疗中的用途,特别是作为5HT受体,特别是5HT 2C受体的激动剂或拮抗剂,例如用于治疗中枢神经系统疾病; 损害中枢神经系统; 心血管疾病; 胃肠道疾病; 尿崩症和睡眠呼吸暂停,特别是用于治疗肥胖。
Abstract:
A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.
Abstract:
An antenna assembly comprising: an antenna; a circuit unit; and a device cover for connection between the antenna and the circuit unit to electrically couple the antenna to the circuit unit.
Abstract:
An antenna assembly comprises an elongate antenna element (11) mounted in a support (5) and movable between a retracted position and an extended position. A helical antenna element (12) in electrical contact with the helical element is carried at one end of the elongate element. The coupling between the feed point and the antenna in the retracted and extended positions allow the same matching circuitry to be used in both conditions. The invention provides a compact and convenient dual antenna arrangement ideally suited for use in a portable cellular radio telephone.
Abstract:
A domed contact element 50 for a keypad assembly comprising a substrate (52) having the dome (54) formed therein, the dome being depressible towards the substrate so as to move from a first natural-bias position to a second position; a soldering site (62) on the substrate by which the contact element can be soldered to a circuit board; and a port (56) positioned between the dome (54) and the soldering site (62) to inhibit ingress of solder into the dome (54) during soldering.
Abstract:
A take-up device for storing a flexible member, such as a cable, cord, flexible hose or tubing and the like, includes a housing for receiving a central portion of the flexible member in in a folded configuration with linear end portions thereof extending outwardly from the housing. The housing includes a member for holding an end portion of the flexible member.
Abstract:
In a media server for processing data packets, media server functions are implemented by a plurality of modules categorized by real-time response requirements.