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公开(公告)号：US20090092635A1
公开(公告)日：2009-04-09
申请号：US12192257
申请日：2008-08-15
Applicant: David Kirkwood Clarke , Farooq Nasar , Rong Xu , Shakuntala Devi Megati , Michael Albin Egan , Amara Gbellu Luckay
Inventor： David Kirkwood Clarke , Farooq Nasar , Rong Xu , Shakuntala Devi Megati , Michael Albin Egan , Amara Gbellu Luckay
IPC: A61K39/12 , A61K39/165 , A61P37/04 , A61P31/12
CPC classification number: A61K39/12 , A61K2039/5254 , A61K2039/5256 , A61K2039/545 , C12N2740/16234 , C12N2760/18734 , C12N2760/18743 , C12N2760/20234 , C12N2760/20243 , Y02A50/412 , Y02A50/466
Abstract: The present invention is directed to a method for generating an antigen-specific immune response in a subject in general and in particular to administering a priming dose of an immunogenic composition of a recombinant mumps virus (rMuV) that encodes an antigen followed by administering a boosting dose of recombinant vesicular stomatitis virus (rVSV) encoding an antigen.
Abstract translation: 本发明涉及在一般的受试者中产生抗原特异性免疫应答的方法，特别是给予起始剂量的编码抗原的重组腮腺炎病毒（rMuV）的免疫原性组合物，然后施用加强 剂量的编码抗原的重组水泡性口炎病毒（rVSV）。
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公开(公告)号：US20060127939A1
公开(公告)日：2006-06-15
申请号：US11341732
申请日：2006-01-27
Applicant: Timothy Woudenberg , Michael Albin , Reid Kowallis , Yefim Raysberg , Robert Raqusa , Emily Winn-Deen
Inventor： Timothy Woudenberg , Michael Albin , Reid Kowallis , Yefim Raysberg , Robert Raqusa , Emily Winn-Deen
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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公开(公告)号：US06825047B1
公开(公告)日：2004-11-30
申请号：US09627580
申请日：2000-07-28
Applicant: Timothy W. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy W. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33543
CPC classification number: B01L3/5027 , B01L3/5025 , B01L3/50273 , B01L3/502738 , B01L7/52 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/049 , C12Q1/08 , G01N35/08 , G01N35/10 , G01N2035/00148 , G01N2035/00356 , G01N2035/1032 , G01N2035/1034 , Y10S436/807
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. The device includes a substrate which defines a sample-distribution network having (i) a sample inlet, (ii) one or more detection chambers, and (iii) channel means providing a dead-end fluid connection between each of the chambers and the inlet. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品的一种或多种选择的分析物的存在，不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 该装置包括限定样品分配网络的基板，其具有（i）样品入口，（ii）一个或多个检测室，以及（iii）通道装置，其在每个室之间提供死端流体连接，并且入口 。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号：US08163538B2
公开(公告)日：2012-04-24
申请号：US11651321
申请日：2007-01-09
Applicant: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. The device includes a substrate which defines a sample-distribution network having (i) a sample inlet, (ii) one or more detection chambers, and (iii) channel means providing a dead-end fluid connection between each of the chambers and the inlet. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品的一种或多种选择的分析物的存在，不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 该装置包括限定样品分配网络的基板，其具有（i）样品入口，（ii）一个或多个检测室，以及（iii）通道装置，其在每个室之间提供死端流体连接，并且入口 。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号：US20110003281A1
公开(公告)日：2011-01-06
申请号：US11811476
申请日：2007-06-11
Applicant: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: C12Q1/68
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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Patent Agency Ranking
公开(公告)号：US07833711B2
公开(公告)日：2010-11-16
申请号：US11400611
申请日：2006-04-07
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: C12Q1/68
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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公开(公告)号：US20080108068A1
公开(公告)日：2008-05-08
申请号：US11807536
申请日：2007-05-29
Applicant: Timothy W. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy W. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: C12Q1/68
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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公开(公告)号：US20080102462A1
公开(公告)日：2008-05-01
申请号：US11811504
申请日：2007-06-11
Applicant: Timothy W. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy W. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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公开(公告)号：US07244622B2
公开(公告)日：2007-07-17
申请号：US11029968
申请日：2005-01-05
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/543 , G01N15/06 , G01N33/53 , G01N33/566 , G01N21/00 , C12Q1/68 , B32B5/02 , B32B27/12 , B01L3/00 , C12M1/34
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品中多种所选分析物中一种或多种的存在，不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号：US07235406B1
公开(公告)日：2007-06-26
申请号：US09628076
申请日：2000-07-28
Applicant: Timothy W. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy W. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/543 , G01N21/00 , G01N15/06 , G01N33/53 , G01N33/533 , G01N33/542 , G01N33/566 , C12Q1/68 , C12M1/34 , B01L3/00 , B32B5/02 , B32B27/12
CPC classification number: G01N21/6452 , B01L3/5027 , B01L7/52 , B01L2200/0642 , B01L2300/0829 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , G01N21/253 , G01N21/6428 , G01N33/54373 , G01N2021/6432 , Y10S436/807
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. The device includes a substrate which defines a sample-distribution network having (i) a sample inlet, (ii) one or more detection chambers, and (iii) channel means providing a dead-end fluid connection between each of the chambers and the inlet. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品的一种或多种选择的分析物的存在，不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 该装置包括限定样品分配网络的基板，其具有（i）样品入口，（ii）一个或多个检测室，以及（iii）通道装置，其在每个室之间提供死端流体连接，并且入口 。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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