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    Laser pulmonary vein isolation
    21.
    发明授权
    Laser pulmonary vein isolation 有权
    激光肺静脉隔离

    公开(公告)号：US06997924B2

    公开(公告)日：2006-02-14

    申请号：US10245613

    申请日：2002-09-17

    Applicant: Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Uri Yaron ,  Marcia Leatham

    Inventor： Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Uri Yaron ,  Marcia Leatham

    IPC: A61B18/18

    CPC classification number: A61B18/24 ,  A61B2017/22051 ,  A61B2018/2272

    Abstract: A catheter introduction apparatus provides an optical assembly for emission of laser light energy. In one application, the catheter and the optical assembly are introduced percutaneously, and transseptally advanced to the ostium of a pulmonary vein. An anchoring balloon is expanded to position a mirror near the ostium of the pulmonary vein, such that light energy is reflected and directed circumferentially around the ostium of the pulmonary vein when a laser light source is energized. A circumferential ablation lesion is thereby produced, which effectively blocks electrical propagation between the pulmonary vein and the left atrium.

    Abstract translation: 导管引入装置提供用于发射激光能量的光学组件。 在一个应用中，导管和光学组件经皮引入，经皮递送到肺静脉的口。 锚固气囊被扩张以在靠近肺静脉的口处定位镜子，使得当激光源被激发时，光能被反射并周向地环绕肺静脉的口引导。 从而产生圆周消融损伤，其有效阻止肺静脉与左心房之间的电传播。

    Intracardiac pressure monitoring method
    23.
    发明授权
    Intracardiac pressure monitoring method 有权

    公开(公告)号：US06652464B2

    公开(公告)日：2003-11-25

    申请号：US09739062

    申请日：2000-12-18

    Applicant: Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Joel Zilberstein ,  Louis J. Capezzuto

    Inventor： Yitzhack Schwartz ,  Assaf Govari ,  Shlomo Ben-Haim ,  Joel Zilberstein ,  Louis J. Capezzuto

    IPC: A61B502

    CPC classification number: A61B5/6882 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/076 ,  A61B2560/0219 ,  A61B2562/0233 ,  A61B2562/046 ,  Y10S128/903

    Abstract: A method for telemetrically measuring a parameter in a patient's heart comprises the steps of imaging the heart and identifying an implantation site in the heart. An opening is created in the tissue at the implantation site. A sensor comprising a housing, a membrane at one end of the housing wherein the membrane is deformable in response to the parameter, and a microchip positioned within the housing and operatively communicating with the membrane for transmitting a signal indicative of the parameter is provided. The sensor is placed in the opening and the parameter is telemetrically measured from outside of the patient's body based on the transmitted signal by the sensor. The sensor is also telemetrically powered from outside of the patient's body. A signal charging and reading device is placed outside of the patient's body for telemetric powering and signal reading with respect to the sensor. In an alternative embodiment, the sensor has a tapered distal end and a tissue piercing tip for direct implantation into tissue. Alternative embodiments of this sensor include helical threads on the tapered distal end for threading the sensor into tissue and a plurality of tissue barbs for direct and firm anchoring of the sensor in tissue.

    Intracardiac drug delivery
    27.
    发明授权
    Intracardiac drug delivery 失效
    心内给药

    公开(公告)号：US06309370B1

    公开(公告)日：2001-10-30

    申请号：US09019453

    申请日：1998-02-05

    Applicant: Shlomo Ben Haim ,  Uri Yaron ,  Avraham Matcovitch

    Inventor： Shlomo Ben Haim ,  Uri Yaron ,  Avraham Matcovitch

    IPC: A61M3100

    CPC classification number: A61M25/0082 ,  A61B2017/00247 ,  A61B2018/00392 ,  A61M25/0075 ,  A61M25/0084 ,  A61M2025/0076 ,  A61M2025/0089 ,  A61M2210/125

    Abstract: Apparatus for intracardiac drug administration, including a catheter which is inserted into a chamber of the heart and brought into engagement with a site in the heart wall. The catheter includes at least one position sensor, which generates signals responsive to the position of the catheter within the heart, and a drug delivery device, which administers a desired dose of a therapeutic drug at the site determined responsive to the signals from the position sensor.

    Abstract translation: 用于心内给药的装置，包括插入心脏腔室并与心壁中的部位接合的导管。 导管包括至少一个位置传感器，其产生响应于心脏内的导管位置的信号，以及药物递送装置，其在响应于来自位置传感器的信号确定的位置处施用期望剂量的治疗药物 。

    Cardiac output controller
    28.
    发明授权
    Cardiac output controller 有权
    心输出控制器

    公开(公告)号：US06298268B1

    公开(公告)日：2001-10-02

    申请号：US09254902

    申请日：1999-03-12

    Applicant: Shlomo Ben-Haim ,  Nissim Darvish ,  Yuval Mika ,  Maier Fenster

    Inventor： Shlomo Ben-Haim ,  Nissim Darvish ,  Yuval Mika ,  Maier Fenster

    IPC: A61N1365

    CPC classification number: A61N1/36514 ,  A61B2017/00243 ,  A61B2017/0243 ,  A61N1/056 ,  A61N1/3627 ,  A61N1/3655 ,  A61N1/36557 ,  A61N1/36564 ,  A61N1/368

    Abstract: This invention is an apparatus for modifying cardiac output of the heart of a subject, including one or more sensors which sense signals responsive to cardiac activity, and a stimulation probe including one or more stimulation electrodes which apply non-excitatory stimulation pulses to a cardiac muscle segment. Signal generation circuitry is coupled to the one or more sensors and the stimulation probe, which circuitry receives the signals from the one or more sensors and generates the non-excitatory stimulation pulses responsive to the signals.

    Abstract translation: 本发明是一种用于修改受试者心脏输出的装置，包括一个或多个感测响应于心脏活动的信号的传感器，以及包括一个或多个刺激电极的刺激探针，所述刺激电极将非兴奋性刺激脉冲应用于心肌 分割。 信号发生电路耦合到一个或多个传感器和刺激探针，该电路接收来自一个或多个传感器的信号，并响应于信号产生非兴奋性刺激脉冲。

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