-
公开(公告)号：US20130337452A1
公开(公告)日：2013-12-19
申请号：US13850683
申请日：2013-03-26
申请人： Steven A. Hofstadler , Thomas A. Hall , David J. Ecker , Lawrence B. Blyn , Mark W. Eshoo , Vivek Samant , Neill White
发明人： Steven A. Hofstadler , Thomas A. Hall , David J. Ecker , Lawrence B. Blyn , Mark W. Eshoo , Vivek Samant , Neill White
IPC分类号： G01N27/62
CPC分类号： G01N27/62 , C12Q1/683 , C12Q1/6846 , G01N27/447 , G16B50/00 , C12Q2565/627 , C12Q2521/301
摘要： The present invention provides methods for rapid forensic analysis of mitochondrial DNA by amplification of a segment of mitochondrial DNA containing restriction sites, digesting the mitochondrial DNA segments with restriction enzymes, determining the molecular masses of the restriction fragments and comparing the molecular masses with the molecular masses of theoretical restriction digests of known mitochondrial DNA sequences stored in a database.
-
公开(公告)号：US20120171692A1
公开(公告)日：2012-07-05
申请号：US11930040
申请日：2007-10-30
CPC分类号： C12Q1/689
摘要： The present invention provides oligonucleotide primers and compositions and kits containing the same for rapid identification of bacteria by amplification of a segment of bacterial nucleic acid followed by molecular mass analysis.
摘要翻译： 本发明提供了寡核苷酸引物和含有该寡核苷酸引物的组合物和试剂盒，用于通过扩增一段细菌核酸进行分子量分析来快速鉴定细菌。
-
公开(公告)号：US20120164625A1
公开(公告)日：2012-06-28
申请号：US13243960
申请日：2011-09-23
申请人： David J. Ecker , Richard H. Griffey , Rangarajan Sampath , Steven A. Hofstadler , John McNeil , Stanley T. Crooke , Lawrence Blyn , Ray Ranken , Thomas A. Hall
发明人： David J. Ecker , Richard H. Griffey , Rangarajan Sampath , Steven A. Hofstadler , John McNeil , Stanley T. Crooke , Lawrence Blyn , Ray Ranken , Thomas A. Hall
CPC分类号： C12Q1/689 , C12Q1/6872 , C12Q1/70 , C12Q1/701 , C12Q2600/16 , G01N1/30 , G01N21/64 , G01N23/00 , G06F19/20
摘要： The present invention provides methods of: identifying pathogens in biological samples from humans and animals, resolving a plurality of etiologic agents present in samples obtained from humans and animals, determining detailed genetic information about such pathogens or etiologic agents, and rapid detection and identification of bioagents from environmental, clinical or other samples.
摘要翻译： 本发明提供了以下方法：鉴定来自人和动物的生物样品中的病原体，解决从人和动物获得的样品中存在的多种病原体，确定关于这种病原体或病原体的详细遗传信息，以及快速检测和鉴定生物代谢 来自环境，临床或其他样品。
-
公开(公告)号：US20120122099A1
公开(公告)日：2012-05-17
申请号：US11683302
申请日：2007-03-07
CPC分类号： C12Q1/689 , C12Q1/6816 , C12Q1/6858 , C12Q2600/156 , C12Q2565/627 , C12Q2537/143
摘要： The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
-
公开(公告)号：US20120094274A1
公开(公告)日：2012-04-19
申请号：US13259375
申请日：2010-05-04
申请人： Rangarajan Sampath , David J. Ecker , Lawrence B. Blyn , Feng Li , Thomas A. Hall , Christian Massire , Roberta Housley , Robert J. Lovari
发明人： Rangarajan Sampath , David J. Ecker , Lawrence B. Blyn , Feng Li , Thomas A. Hall , Christian Massire , Roberta Housley , Robert J. Lovari
IPC分类号： C12Q1/70
CPC分类号： C12Q1/6846 , C12Q1/6888 , C12Q1/701 , C12Q2537/143
摘要： The present invention provides oligonucleotide primers, compositions, and kits containing the same for rapid identification of viruses (e.g., swine-origin influenza A (H1N1) virus) which are members of the influenza virus family by amplification of a segment of viral nucleic acid followed by molecular mass analysis.
摘要翻译： 本发明提供了含有它们的寡核苷酸引物，组合物和试剂盒，用于通过扩增一段病毒核酸来快速鉴定病毒（例如，猪源甲型流感（H1N1）病毒）），其是流感病毒家族的成员 通过分子量分析。
-
公开(公告)号：US20120064523A1
公开(公告)日：2012-03-15
申请号：US13259350
申请日：2010-03-30
申请人： David J. Ecker , Steven A. Hofstadler , Rangarajan Sampath , Lawrence B. Blyn , Thomas A. Hall , Mark W. Eshoo
发明人： David J. Ecker , Steven A. Hofstadler , Rangarajan Sampath , Lawrence B. Blyn , Thomas A. Hall , Mark W. Eshoo
CPC分类号： B01L3/502761 , B01L3/5027 , B01L3/52 , B01L7/52 , B01L2200/028 , B01L2200/10 , B01L2300/027 , B01L2400/0415 , H01J49/0022
摘要： The present invention relates to portable systems and devices, and corresponding methods, for detecting bioagents. In particular, the present invention provides systems, devices, and methods that utilize one or more of a sample preparation component, sample analysis component employing broad range primers, and sample detection component.
摘要翻译： 本发明涉及用于检测生物代理的便携式系统和装置及相应的方法。 特别地，本发明提供利用样品制备组分，采用宽范围引物的样品分析组分和样品检测组分中的一种或多种的系统，装置和方法。
-
27.发明授权公开(公告)号：US08026084B2
公开(公告)日：2011-09-27
申请号：US11491376
申请日：2006-07-21
IPC分类号： C12P19/34
CPC分类号： C12Q1/6872 , C12Q1/6827 , C12Q1/6844 , C12Q1/6858 , C12Q1/6881 , C12Q2600/156 , C12Q2600/16 , C12Q2565/627 , C12Q2537/143 , C12Q2531/113 , C12Q2545/10
摘要： There is a need for nucleic acid analysis which is both specific and rapid, and in which no nucleic acid sequencing is required. The present invention addresses this need, among others by providing a method of nucleic acid amplification of overlapping sub-segments of a nucleic acid followed by molecular mass measurement of resulting amplification products by mass spectrometry, and determination of the base compositions of the amplification products.
摘要翻译： 需要具有特异性和快速性的核酸分析，并且其中不需要核酸测序。 本发明除了提供核酸扩增核酸扩增方法之外，还通过质谱法对所得扩增产物进行分子量测定，以及确定扩增产物的碱基组成来解决这一需要。
-
28.发明申请公开(公告)号：US20110190170A1
公开(公告)日：2011-08-04
申请号：US13122350
申请日：2009-09-30
申请人： Rangarajan Sampath , David J. Ecker , Robert J. Lovari , Feng Li , Lawrence B. Blyn , Thomas A. Hall
发明人： Rangarajan Sampath , David J. Ecker , Robert J. Lovari , Feng Li , Lawrence B. Blyn , Thomas A. Hall
CPC分类号： C12Q1/689 , C12Q2600/156
摘要： The present invention relates generally to identification of antibiotic-resistant bacteria and provides methods, compositions and kits useful for this purpose when combined, for example, with molecular mass or base composition analysis.
摘要翻译： 本发明一般涉及抗生素抗性细菌的鉴定，并提供了用于此目的的方法，组合物和试剂盒，例如当与分子量或碱组成分析组合时。
-
公开(公告)号：US20110151437A1
公开(公告)日：2011-06-23
申请号：US12995947
申请日：2009-06-01
申请人： Rangarajan Sampath , Feng Li , Rachael Kreft , Thomas A. Hall , Lawrence B. Blyn
发明人： Rangarajan Sampath , Feng Li , Rachael Kreft , Thomas A. Hall , Lawrence B. Blyn
CPC分类号： C12Q1/701 , C12Q1/6872
摘要： The present invention provides compositions, kits and methods for rapid identification and quantification of adventitious contaminant viruses by molecular mass and base composition analysis.
摘要翻译： 本发明提供了通过分子质量和基础组成分析快速鉴定和定量异源污染物病毒的组合物，试剂盒和方法。
-
公开(公告)号：US07718354B2
公开(公告)日：2010-05-18
申请号：US10728486
申请日：2003-12-05
申请人： David J. Ecker , Richard H. Griffey , Rangarajan Sampath , Steven A. Hofstadler , John McNeil , Stanley T. Crooke , Lawrence B. Blyn , Raymond Ranken , Thomas A. Hall
发明人： David J. Ecker , Richard H. Griffey , Rangarajan Sampath , Steven A. Hofstadler , John McNeil , Stanley T. Crooke , Lawrence B. Blyn , Raymond Ranken , Thomas A. Hall
摘要： The present invention provides methods of: identifying pathogens in biological samples from humans and animals, resolving a plurality of etiologic agents present in samples obtained from humans and animals, determining detailed genetic information about such pathogens or etiologic agents, and rapid detection and identification of bioagents from environmental, clinical or other samples.
-
-
-
-
-
-
-
-
-
搜索结果
82 条记录 (耗时 0.066 秒)
