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29 条记录 (耗时 0.023 秒)

    OPTICAL MEASURING INSTRUMENT
    21.
    发明申请
    OPTICAL MEASURING INSTRUMENT 审中-公开
    光学测量仪器

    公开(公告)号：US20100110439A1

    公开(公告)日：2010-05-06

    申请号：US12449649

    申请日：2008-02-25

    申请人： Roman Gruler ,  Konrad Faulstich

    发明人： Roman Gruler ,  Konrad Faulstich

    IPC分类号： G01N21/01 ,  G01N1/10 ,  G01N21/55 ,  G01T1/10

    CPC分类号： G01N21/645 ,  G01N21/255 ,  G01N21/8483 ,  G01N2201/0228 ,  G01N2201/024

    摘要： The invention provides for an optical measuring instrument and measuring device. The optical measuring instrument for investigating a specimen contained in a sample comprises at least one source for providing at least one electromagnetic beam intended to irradiate the sample and to interact with the specimen within the sample, at least one sensor for detecting an output of the interaction between the specimen and the electromagnetic beam, an integrally formed mechanical bench for the optical and electronic components, a sample holder for holding the sample, wherein the at least one source, the at least one sensor, and the mechanical bench are integrated in one monolithic optoelectronic module and the sample holder can be connected to this module.

    摘要翻译： 本发明提供一种光学测量仪器和测量装置。 用于调查包含在样品中的样本的光学测量仪器包括至少一个源，用于提供用于照射样品的至少一个电磁束并与样品内的样品相互作用，用于检测相互作用的输出的至少一个传感器 在样品和电磁束之间，用于光学和电子部件的整体形成的机械台，用于保持样品的样品保持器，其中所述至少一个源，所述至少一个传感器和所述机械台被集成在一个单片 光电模块和样品架可以连接到该模块。

    Electrochemical polynucleotide detection comprising ligation
    23.
    发明授权
    Electrochemical polynucleotide detection comprising ligation 失效
    包含连接的电化学多核苷酸检测

    公开(公告)号：US08551697B1

    公开(公告)日：2013-10-08

    申请号：US11609111

    申请日：2006-12-11

    申请人： Vladimir I. Bashkirov ,  Konrad Faulstich

    发明人： Vladimir I. Bashkirov ,  Konrad Faulstich

    IPC分类号： C12Q1/68 ,  C12P19/36 ,  C12P19/34 ,  C07H21/02 ,  C07H21/04

    CPC分类号： C12Q1/6834 ,  C12Q1/6825 ,  C12Q1/6823 ,  C12Q2521/501 ,  C12Q2563/113 ,  C12Q2565/607

    摘要： Disclosed, for example, are methods comprising cleaving an uncleaved probe to form a cleaved oligonucleotide flap, forming a hybridization complex between the cleaved oligonucleotide flap, a bridging oligonucleotide, and a capture oligonucleotide that is immobilized on a surface, such that the oligonucleotide flap and the capture oligonucleotide are hybridized to immediately adjacent, complementary regions of the bridging oligonucleotide, ligating the oligonucleotide flap to the capture oligonucleotide to form an immobilized ligation product, and detecting the ligation product.

    摘要翻译： 公开了例如，切割未切割的探针以形成切割的寡核苷酸瓣，在切割的寡核苷酸瓣，桥连寡核苷酸和固定在表面上的捕获寡核苷酸之间形成杂交复合物的方法，使得寡核苷酸瓣和 将捕获寡核苷酸与桥接寡核苷酸的紧邻的互补区域杂交，将寡核苷酸片段连接至捕获寡核苷酸以形成固定化的连接产物，并检测连接产物。

    FLUORESCENCE STANDARD, AND THE USE THEREOF
    24.
    发明申请
    FLUORESCENCE STANDARD, AND THE USE THEREOF 有权
    荧光标准及其使用

    公开(公告)号：US20110076687A1

    公开(公告)日：2011-03-31

    申请号：US12937009

    申请日：2009-04-17

    申请人： Klaus Haberstroh ,  Konrad Faulstich

    发明人： Klaus Haberstroh ,  Konrad Faulstich

    IPC分类号： G01J1/10 ,  G01N21/64 ,  C12Q1/68 ,  C12Q1/04 ,  C12M1/34 ,  G01N23/00

    CPC分类号： G01N21/278 ,  B01L3/50857 ,  B01L3/5088 ,  B01L2200/148 ,  B01L2300/0822 ,  B01L2300/0829 ,  G01K11/14 ,  G01N1/28 ,  G01N21/6452 ,  G01N2001/2893 ,  G01N2015/1018 ,  G01T1/362 ,  Y10T436/10

    摘要： The invention concerns fluorescence standards, and in particular fluorescence standards for calibrating optical detectors. According to the invention, a fluorescent mineral or mixtures of minerals are employed for use as a fluorescence standard. The fluorescent mineral can be a naturally occurring mineral or a synthetically produced mineral. Preferred fluorescent minerals for use as fluorescence standards are corundum, fluorite, turquoise, amber, zircon, zoisite, iolite or cordierite, spinel, topaz, calcium fluorite, sphalerite or zincblende, calcite or calcspar, apatite, scheelite or calcium tungstate, willemite, feldspars, sodalite, a uranium mineral, a mineral containing Al3+, and in particular ruby and sapphire.

    摘要翻译： 本发明涉及荧光标准，特别是用于校准光学检测器的荧光标准。 根据本发明，荧光矿物或矿物质的混合物用作荧光标准。 荧光矿物可以是天然存在的矿物质或合成产生的矿物质。 用作荧光标准的优选的荧光矿物是刚玉，萤石，绿松石，琥珀，锆石，堇青石，石英或堇青石，尖晶石，黄玉，萤石，闪锌矿或闪锌矿，方解石或钙质，磷灰石，白钨矿或钨酸钙，硅锌矿，长石 ，钠盐，铀矿物质，含有Al3 +的矿物，特别是红宝石和蓝宝石。

    Sample holder and method of using the same
    26.
    发明授权
    Sample holder and method of using the same 失效
    样品夹持器及其使用方法

    公开(公告)号：US08563326B2

    公开(公告)日：2013-10-22

    申请号：US12933832

    申请日：2009-03-31

    申请人： Klaus Haberstroh ,  Konrad Faulstich

    发明人： Klaus Haberstroh ,  Konrad Faulstich

    IPC分类号： G01N33/53

    CPC分类号： G01N21/03 ,  B01L3/50857 ,  B01L3/5088 ,  B01L2200/142 ,  B01L2300/04 ,  B01L2300/0822 ,  B01L2300/0861 ,  B01L2300/161 ,  G01N21/25 ,  G01N21/278 ,  G01N21/64 ,  G01N21/76 ,  G01N35/00029 ,  G01N2021/0325 ,  G01N2021/0346 ,  G01N2021/035 ,  G02B21/34

    摘要： A sample holder, such as a microscope slide, is provided in the form of a card-shaped substrate or plate, preferably for use in an analytical reader. The sample holder comprises at least one hole, preferably a plurality of holes, for receiving a sample to be analyzed. The at least one hole extends completely through the substrate and is sized such that the sample is held within the at least one hole by means of the surface tension of the sample against the force of gravity. Optionally the substrate comprises a first upper substrate and a second lower substrate that together embed a porous membrane. As a further option the sample holder comprises a first cover attached to the top side of the first upper substrate and/or a second cover attached to the bottom side of the second lower substrate. Moreover a method for using such a sample holder in an analytical reader is provided, comprising the steps of: filling the at least one hole of the sample holder with a sample and reagent mixture; inserting the sample holder in the analytical reader; and analyzing the sample and reagent mixture in the at least one hole of the sample holder with the analytical reader.

    摘要翻译： 样品架（例如显微镜载玻片）以卡形基板或板的形式提供，优选用于分析读取器。 样品架包括用于接收待分析样品的至少一个孔，优选多个孔。 所述至少一个孔完全延伸穿过基底，并且其尺寸设计成使得样品通过样品的表面张力抵抗重力而保持在至少一个孔内。 可选地，基底包括一起嵌入多孔膜的第一上基底和第二下基底。 作为另一选择，样品架包括附接到第一上基板的顶侧的第一盖和/或附接到第二下基板的底侧的第二盖。 此外，提供了一种在分析读取器中使用这种样品保持器的方法，包括以下步骤：用样品和试剂混合物填充样品架的至少一个孔; 将样品架插入分析读数器; 并用分析读取器分析样品架的至少一个孔中的样品和试剂混合物。

    Porous Polymer Electrodes
    29.
    发明申请
    Porous Polymer Electrodes 审中-公开
    多孔聚合物电极

    公开(公告)号：US20100092867A1

    公开(公告)日：2010-04-15

    申请号：US12504488

    申请日：2009-07-16

    申请人： Aldrich N.K. Lau ,  Konrad Faulstich ,  Kristian M. Scaboo

    发明人： Aldrich N.K. Lau ,  Konrad Faulstich ,  Kristian M. Scaboo

    IPC分类号： H01M4/58 ,  H01M4/02

    CPC分类号： G01N27/3335

    摘要： Porous polymer electrode assemblies are useful in the detection or quantification of a variety of analytes. By preparing a porous monolith, and applying a conductive polymer to the monolith, a porous matrix is prepared that combines favorable conductive properties, by virtue of the presence of the conductive polymer, with the porous character of the underlying monolith. The resulting porous electrode can be used for qualitative or quantitative analysis, and the capture and/or release of selected charged materials, such as nucleic acids. The pores of the electrode matrix may also be filled with nonconductive material, yielding electrodes having a plurality of discrete conductive surfaces.

    摘要翻译： 多孔聚合物电极组件可用于检测或定量各种分析物。 通过制备多孔整料并将导电聚合物施加到整料上，制备出多孔基质，其通过导电聚合物的存在与下面的整料的多孔特征结合有利的导电性能。 所得的多孔电极可用于定性或定量分析，以及所选择的带电材料（例如核酸）的捕获和/或释放。 电极基体的孔也可以用非导电材料填充，产生具有多个离散导电表面的电极。