Passivated and stabilized porous mineral oxide supports and method for
the preparation and use of same
    22.
    发明授权
    Passivated and stabilized porous mineral oxide supports and method for the preparation and use of same 失效
    钝化和稳定的多孔矿物氧化物载体及其制备和使用方法

    公开(公告)号:US5268097A

    公开(公告)日:1993-12-07

    申请号:US956404

    申请日:1992-10-05

    IPC分类号: B01D15/08 B01J20/32 B01J39/16

    摘要: This invention relates generally to modified porous solid supports and processes for the preparation and use of same. In particular, passivated porous mineral oxide supports are disclosed that are stabilized against leaching under harsh environmental conditions by the application of a thin, protective polymeric coating atop their porous surfaces and that are characterized by a reversible high sorptive capacity substantially unaccompanied by non-specific adsorption of or interaction with biomolecules. Passivation is achieved by the use of a passivation mixture comprising a main monomer, a passivating monomer that is different from the main monomer, and a crosslinking agent, which mixture upon polymerization results in the substantial elimination of the undesirable non-specific interaction between biomolecules and the protective polymeric coating on the surfaces of the mineral oxide matrix.

    摘要翻译: 本发明一般涉及改性多孔固体载体及其制备和使用方法。 特别地,公开了钝化的多孔无机氧化物载体,其在恶劣的环境条件下通过在其多孔表面顶上施加薄的保护性聚合物涂层而稳定化,并且其特征在于基本上不伴随非特异性吸附的可逆的高吸附能力 或与生物分子相互作用。 通过使用包含主单体,不同于主单体的钝化单体和交联剂的钝化混合物来实现钝化,该聚合物上的该混合物导致基本上消除生物分子与生物分子之间不合需要的非特异性相互作用 矿物氧化物基体表面上的保护性聚合物涂层。

    Multi-compartment filter and method of filtering using same
    26.
    发明申请
    Multi-compartment filter and method of filtering using same 有权
    多室过滤器和使用其的过滤方法

    公开(公告)号:US20050205427A1

    公开(公告)日:2005-09-22

    申请号:US11073999

    申请日:2005-03-08

    摘要: Each embodiment includes a central sample reservoir and a plurality of satellite reservoirs. In a first embodiment, a first electrode in electrical contact with the central reservoir is charged and second electrodes in electrical contact with the satellite reservoirs are sequentially charged, thereby pI filtering molecules in the central reservoir into the satellite reservoirs. In a second embodiment, the central reservoir is configured to rotate so that molecules in a sample in the central reservoir are centrifugally pI-filtered into the satellite reservoirs. In a third embodiment, first and second electrodes proximate opposite first and second satellite reservoirs, respectively, are charged. Some molecules in a sample are pI filtered into the first and second satellite reservoirs. Third and fourth electrodes proximate opposite third and fourth satellite reservoirs, respectively, are then charged. Some molecules in a sample are pI filtered into the third and fourth satellite reservoirs.

    摘要翻译: 每个实施例包括中央样品储存器和多个卫星储存器。 在第一实施例中,与中央储存器电接触的第一电极被充电,并且与卫星储存器电接触的第二电极被顺序地充电,从而将中央储存器中的分子过滤到卫星储存器中。 在第二实施例中,中央储存器被配置为旋转,使得中央储存器中的样品中的分子被离心地pI过滤到卫星储存器中。 在第三实施例中,分别与第一和第二卫星储存器相邻的第一和第二电极被充电。 样品中的一些分子被pI过滤到第一和第二卫星储层中。 然后分别靠近相对的第三和第四卫星储存器的第三和第四电极被充电。 样品中的一些分子被pI过滤到第三和第四卫星储层中。

    Detection of ion concentration in a liquid
    30.
    发明授权
    Detection of ion concentration in a liquid 失效
    检测液体中的离子浓度

    公开(公告)号:US4590424A

    公开(公告)日:1986-05-20

    申请号:US535307

    申请日:1983-09-23

    IPC分类号: G01N27/06 G01N27/02 G01N27/74

    CPC分类号: G01N27/023

    摘要: A detector of ion concentration in a liquid is composed of a detection cell comprising a tubular piece formed from an electrically insulating material with a central passage which is fed with a liquid whose ion concentration is to be measured. A conducting coil is placed around the tubular piece, and is part of a first resonant circuit. A second reference resonant circuit is also provided, and signals of fixed frequency are applied in parallel to the two resonant circuits, and a comparator delivers a signal having a magnitude representative of the difference between the output signals from the two resonant circuits. Such a detector finds a use for example in liquid chromatography.

    摘要翻译: 液体中的离子浓度检测器由检测单元构成,该检测单元由具有中间通道的电绝缘材料形成的管状件构成,该中间通道供给被测量离子浓度的液体。 导电线圈放置在管状件周围,并且是第一谐振电路的一部分。 还提供了第二参考谐振电路,并且固定频率的信号并联施加到两个谐振电路,并且比较器输出具有表示来自两个谐振电路的输出信号之间的差的幅度的信号。 这种检测器可用于例如液相色谱法。