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公开(公告)号：US07772092B2
公开(公告)日：2010-08-10
申请号：US12314997
申请日：2008-12-19
申请人： Kentaro Iizuka , Hirokazu Matsumoto , Ryugo Oba
发明人： Kentaro Iizuka , Hirokazu Matsumoto , Ryugo Oba
IPC分类号： H01L21/268
CPC分类号： H01L21/67092 , B23K26/0853 , B23K26/364 , B23K26/40 , B23K2103/172 , B23K2103/50 , H01L21/78
摘要： A method of processing a wafer having a plurality of devices which are composed of a laminate consisting of an insulating film and a functional film on the front surface of a substrate, along streets for sectioning the plurality of devices, the method comprising a first blocking groove forming step for forming a first blocking groove for dividing the laminate in a one-side portion in the width direction of a street of the wafer held on a chuck table by moving the chuck table in a first direction in the processing-feed direction while activating a first laser beam application means; and a second blocking groove and dividing groove forming step for forming a second blocking groove which divides the laminate in the other-side portion in the width direction of the street of the wafer which has undergone the first blocking groove forming step by moving the chuck table in a second direction in the processing-feed direction while activating the first laser beam application means and at the same time, forming a dividing groove in the laminate and the substrate along an intermediate portion between the first blocking groove and the second blocking groove formed in the street of the wafer by activating second laser beam application means.
摘要翻译： 一种处理具有多个器件的晶片的方法，所述晶片具有由基板前表面上的绝缘膜和功能膜构成的层叠体，沿着用于切割所述多个器件的街道，所述方法包括：第一阻挡槽 形成步骤，用于形成第一阻挡槽，用于在保持在卡盘台上的晶片的街道的宽度方向上沿着处理进给方向的第一方向移动卡盘台，沿着处理进给方向分割层压体， 第一激光束施加装置; 以及第二阻挡槽和分隔槽形成步骤，用于形成第二阻挡槽，该第二阻挡槽通过移动卡盘台，在已经经历了第一阻挡槽形成步骤的晶片的街道的宽度方向上的另一侧部分中分层叠层 沿着处理供给方向的第二方向，同时激活第一激光束施加装置，并且同时沿着形成在第一阻挡槽和第二阻挡槽之间的中间部分的层叠体和基板中形成分隔槽 通过激活第二激光束施加装置的晶片的街道。
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公开(公告)号：US07691979B2
公开(公告)日：2010-04-06
申请号：US11498439
申请日：2006-08-02
IPC分类号： C07K16/00
CPC分类号： G01N33/689 , C07K16/18 , G01N33/6857 , G01N2800/368
摘要： The present invention aims at providing an antibody, by which metastin or its derivative can be quantified specifically with a high sensitivity, a method of detecting/quantifying metastin or its derivative using the antibody, and a diagnostic agent (e.g., a diagnostic for pregnancy) the same. Specifically, an antibody capable of specifically reacting with a partial peptide at the N-terminus or C-terminus of a polypeptide having the amino acid sequence represented by SEQ ID NO: 1 or its derivative, and a method of detecting/quantifying metastin or its derivative using the antibody as well as a diagnostic agent using the same.
摘要翻译： 本发明的目的在于提供抗体，通过该抗体可以以高灵敏度特异性地定量分析蛋白或其衍生物，使用抗体检测/定量分析蛋白或其衍生物的方法，以及诊断剂（例如，怀孕诊断） 一样。 具体而言，能够与具有SEQ ID NO：1所示的氨基酸序列的多肽的N末端或C末端的部分肽特异性反应的抗体或其衍生物，以及检测/定量分析的方法 衍生物以及使用该抗体的诊断剂。
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公开(公告)号：US07173112B2
公开(公告)日：2007-02-06
申请号：US10490917
申请日：2002-09-25
IPC分类号： C07K16/00
CPC分类号： C07K16/26 , A61K2039/505 , G01N33/74
摘要： The present invention intends to provide a novel monoclonal antibody having a binding specificity to GALP or its derivative, which is useful in developing therapeutic agents, preventive agents or diagnostic agent for diseases associated with GALP or its derivative, and a method of quantifying GALP using the antibody. More specifically, the present invention provides an antibody specifically reacting with a partial peptide in the C-terminal region of a polypeptide having the amino acid sequence represented by SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3, or its derivative, and a method of quantifying GALP or its derivative.
摘要翻译： 本发明旨在提供具有对GALP或其衍生物的结合特异性的新型单克隆抗体，其可用于开发与GALP或其衍生物相关的疾病的治疗剂，预防剂或诊断剂，以及使用 抗体。 更具体地，本发明提供了具有与SEQ ID NO：1，SEQ ID NO：2或SEQ ID NO：3所示的氨基酸序列的多肽的C-末端区域中的部分肽特异性反应的抗体，或 其衍生物，以及量化GALP或其衍生物的方法。
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公开(公告)号：US20070014799A1
公开(公告)日：2007-01-18
申请号：US10576066
申请日：2004-10-21
申请人： Hirokazu Matsumoto , Jiro Noguchi , Yasushi Masuda
发明人： Hirokazu Matsumoto , Jiro Noguchi , Yasushi Masuda
IPC分类号： G01N33/567 , A61K39/395 , C07K16/22
CPC分类号： C07K16/18 , A61K2039/505 , C07K16/22 , C07K2317/76
摘要： The present invention provides a novel antibody useful in developing therapeutic, preventive and diagnostic agents for diseases associated with human ZAQL-2, a method of quantifying ZAQL-2 by using the antibody, etc. More particularly, the present invention provides an antibody reacting specifically with human ZAQL-2 or its derivatives, a method of quantifying ZAQL-2 by using the antibody, a pharmaceutical drug comprising the antibody, and so on.
摘要翻译： 本发明提供了可用于开发与人ZAQL-2相关疾病的治疗，预防和诊断剂的新型抗体，通过使用抗体定量ZAQL-2的方法等。更具体地，本发明提供了一种抗体特异性反应 使用人ZAQL-2或其衍生物，通过使用抗体定量ZAQL-2的方法，包含抗体的药物等。
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公开(公告)号：US20060275286A1
公开(公告)日：2006-12-07
申请号：US11498439
申请日：2006-08-02
IPC分类号： A61K39/395 , G01N33/53 , C12P21/04 , C12N5/06 , C07K16/26
CPC分类号： G01N33/689 , C07K16/18 , G01N33/6857 , G01N2800/368
摘要： The present invention aims at providing an antibody, by which metastin or its derivative can be quantified specifically with a high sensitivity, a method of detecting/quantifying metastin or its derivative using the antibody, and a diagnostic agent (e.g., a diagnostic for pregnancy) the same. Specifically, an antibody capable of specifically reacting with a partial peptide at the N-terminus or C-terminus of a polypeptide having the amino acid sequence represented by SEQ ID NO: 1 or its derivative, and a method of detecting/quantifying metastin or its derivative using the antibody as well as a diagnostic agent using the same.
摘要翻译： 本发明的目的在于提供抗体，通过该抗体可以以高灵敏度特异性地定量分析蛋白或其衍生物，使用抗体检测/定量分析蛋白或其衍生物的方法，以及诊断剂（例如，怀孕诊断） 一样。 具体而言，能够与具有SEQ ID NO：1所示的氨基酸序列的多肽的N末端或C末端的部分肽特异性反应的抗体或其衍生物，以及检测/定量分析的方法 衍生物以及使用该抗体的诊断剂。
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公开(公告)号：US07112662B2
公开(公告)日：2006-09-26
申请号：US10490125
申请日：2002-09-18
IPC分类号： C07K16/00
CPC分类号： G01N33/689 , C07K16/18 , G01N33/6857 , G01N2800/368
摘要： The present invention aims at providing an antibody, by which metastin or its derivative can be quantified specifically with a high sensitivity, a method of detecting/quantifying metastin or its derivative using the antibody, and a diagnostic agent (e.g., a diagnostic for pregnancy) the same.Specifically, an antibody capable of specifically reacting with a partial peptide at the N-terminus or C-terminus of a polypeptide having the amino acid sequence represented by SEQ ID NO: 1 or its derivative, and a method of detecting/quantifying metastin or its derivative using the antibody as well as a diagnostic agent using the same.
摘要翻译： 本发明的目的在于提供抗体，通过该抗体可以以高灵敏度特异性地定量分析蛋白或其衍生物，使用抗体检测/定量分析蛋白或其衍生物的方法，以及诊断剂（例如，怀孕诊断） 一样。 具体而言，能够与具有SEQ ID NO：1所示的氨基酸序列的多肽的N末端或C末端的部分肽特异性反应的抗体或其衍生物，以及检测/定量分析的方法 衍生物以及使用该抗体的诊断剂。
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27.发明授权Method and apparatus for positioning object in space using a low-coherence laser beam which is reflected by two references to sharpen the interference fringe lines 失效使用低相干激光束在空间中定位物体的方法和装置，其被两个参考线反射以锐化干涉条纹线
公开(公告)号：US6064481A
公开(公告)日：2000-05-16
申请号：US917804
申请日：1997-08-27
CPC分类号： G01B9/0209 , G01B9/02028
摘要： An object is positioned in space by using a beam splitter to split a low-coherence laser light beam into a probe beam and a reference beam. The probe beam is projected at the target object, while the reference beam is reflected by a pair of mirrors synchronized along light paths and scanned at different amplitudes, to form two beams of equal intensity, and light reflected by the object and the interference fringes are detected together to obtain fringe signals with sharpened profile lines.
摘要翻译： 物体通过使用分束器将低相干激光束分裂成探测光束和参考光束而位于空间中。 探测光束投影在目标物体上，而参考光束被沿着光路同步并以不同幅度扫描的一对反射镜反射，形成两个相等强度的光束，物体反射的光和干涉条纹是 一起检测以获得具有锐化轮廓线的条纹信号。
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公开(公告)号：US20130003038A1
公开(公告)日：2013-01-03
申请号：US13518727
申请日：2011-01-28
申请人： Takehiro Tachizaki , Masahiro Watanabe , Tatsuo Hariyama , Yasuhiro Yoshitake , Tetsuya Matsui , Hirokazu Matsumoto , Kiyoshi Takamasu
发明人： Takehiro Tachizaki , Masahiro Watanabe , Tatsuo Hariyama , Yasuhiro Yoshitake , Tetsuya Matsui , Hirokazu Matsumoto , Kiyoshi Takamasu
IPC分类号： G01C3/08
CPC分类号： G01S17/36 , G01B9/02003 , G01B9/02007 , G01B9/02008 , G01B9/0207 , G01S7/4815 , G01S7/4911 , G01S17/42
摘要： Disclosed is a distance measuring device using an optical comb. In order for the absolute distance to an object to be measured which has a surface with low reflection ratio or a scattering surface and is approximately 10 m apart, to be easily measured with accuracy of 0.1 mm or more using an optical and contactless method, the distance measuring device which measures the distance to the object to be measured is configured such that the distance to the object to be measured is measured by comparing the phase of the beat signal between a light source and a plurality of CW lasers which are reflected or scattered by the object with the phase of the beat signal between the light source and a plurality of CW lasers prior to being irradiated onto the object.
摘要翻译： 公开了使用光梳的距离测量装置。 为了使具有低反射率或散射面的表面的测量对象的绝对距离相差10微米，使用光学和非接触方法可以容易地测量精度为0.1mm以上， 测量到被测量物体的距离的距离测量装置被配置为通过比较反射或散射的光源和多个CW激光器之间的拍频信号的相位来测量到被测量物体的距离 在被照射到物体上之前，通过光源和多个CW激光器之间的拍频信号的相位的对象。
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公开(公告)号：US20090318365A1
公开(公告)日：2009-12-24
申请号：US12455563
申请日：2009-06-02
申请人： Chieko Kitada , Taiji Asami , Naoko Nishizawa , Tetsuya Ohtaki , Naoki Tarui , Hirokazu Matsumoto , Jiro Noguchi , Hisanori Matsui
发明人： Chieko Kitada , Taiji Asami , Naoko Nishizawa , Tetsuya Ohtaki , Naoki Tarui , Hirokazu Matsumoto , Jiro Noguchi , Hisanori Matsui
摘要： The present invention provides a metastin derivative in which the amino acids comprising metastin were modified by alternative chemical substituents resulting in metastin derivatives, having excellent blood stability and exhibiting cancer metastasis inhibiting action or cancer growth inhibiting action.
摘要翻译： 本发明提供了一种转氨酶衍生物，其中包含转氨酶的氨基酸被替代的化学取代基修饰，导致转氨酶衍生物，具有优异的血液稳定性和显示出癌转移抑制作用或癌生长抑制作用。
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公开(公告)号：US20090138757A1
公开(公告)日：2009-05-28
申请号：US12041059
申请日：2008-03-03
IPC分类号： G06F11/14
CPC分类号： G06F11/2025 , G06F11/0709 , G06F11/0793 , G06F11/1438 , G06F11/2041 , G06F11/2043
摘要： There is provided a method executed in a cluster system comprising a first computer and at least one second computer that stores the data transmitted from the first computer. The method comprising the steps of: judging whether the failure-occurred processing is restarted by the first computer or the failure-occurred processing is switched over by the second computer based on the system information; receiving the stored data from the second computer and re-executing the processing in which the failure has occurred by the first computer, in the case of which it is judged that the processing in which the failure has occurred is restarted by the first computer; and executing, by the second computer, the processing in which the failure has occurred, in the case of which it is judged that the processing in which the failure has occurred is switched over by the at least one second computer.
摘要翻译： 提供了一种在包括第一计算机和存储从第一计算机发送的数据的至少一个第二计算机的集群系统中执行的方法。 该方法包括以下步骤：基于系统信息，判断第一计算机重新启动故障发生处理或由第二计算机切换故障发生处理; 从所述第二计算机接收所述存储的数据并重新执行由所述第一计算机发生所述故障的处理，在判断已经发生所述故障的处理由所述第一计算机重新启动的情况下; 并且由所述第二计算机执行在所述至少一个第二计算机切换已经发生故障的处理的情况下发生故障的处理。
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