公开(公告)号：US20090082623A1

公开(公告)日：2009-03-26

申请号：US11810850

申请日：2007-06-07

申请人： Chris A. Rothe ,  Vahid Saadat ,  Kevin H. Van Bladel

发明人： Chris A. Rothe ,  Vahid Saadat ,  Kevin H. Van Bladel

IPC分类号： A61B1/04

CPC分类号： A61B1/3137 ,  A61B1/00082 ,  A61B1/00089 ,  A61B1/00147 ,  A61B17/0057 ,  A61B17/064 ,  A61B2017/00243 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/0061 ,  A61B2017/00615 ,  A61B2017/00623 ,  A61B2017/0641

摘要： Visualization and treatment of tissue regions via percutaneous access methods and devices are described herein. The system may include a deployment catheter and an expandable imaging hood. In use, the hood may be introduced from outside the patient body through a percutaneous incision and advanced through a subxiphoid pathway, for example, to the heart where entry may be accomplished via an incision through the left atrial appendage. Once within the heart, the hood can be advanced to any chamber to visualize and/or treat tissue by placing the hood against the tissue to be imaged and pumping translucent fluids into the hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for treating the tissue of interest.

摘要翻译： 本文描述了通过经皮访问方法和装置对组织区域的可视化和治疗。 该系统可以包括展开导管和可扩展成像罩。 在使用中，引擎盖可以通过经皮切口从患者身体的外部引入，并穿过亚剑突途径，例如穿过左心耳通过切口进入心脏。 一旦在心脏内，通过将罩放置在待成像的组织上并将半透明流体泵入罩中直到流体移动任何血液，从而留下清晰的区域 要通过部署导管中的成像元件成像的组织。 此外，任何数量的治疗工具也可以通过展开导管并进入成像罩以用于感兴趣的组织。

公开(公告)号：US20080200821A1

公开(公告)日：2008-08-21

申请号：US12110585

申请日：2008-04-28

申请人： Vahid Saadat

发明人： Vahid Saadat

IPC分类号： A61B5/1495 ,  A61B5/0215

CPC分类号： A61B5/14542 ,  A61B5/1459 ,  A61B5/6848

摘要： Left atrial access apparatus and methods are described herein. Different parameters, such as oxygen saturation difference, between the left and right atrial chambers is utilized to guide a needle or catheter into a desired position within the heart. Various sensing elements can be utilized to detect the physiological parameter difference, such as oxygen levels, in the left atrium. The sensor can be carried by the needle, at its tip or along its body, and can measure the physiological parameter levels contained in the blood, fluid, or tissue.

摘要翻译： 本文描述了左心房接入装置和方法。 使用左心房和右心房之间的不同参数（例如氧饱和度差异）将针或导管引导到心脏内的期望位置。 可以使用各种感测元件来检测左心房中的生理参数差异，例如氧水平。 传感器可以由针头，其尖端或沿其身体携带，并且可以测量包含在血液，流体或组织中的生理参数水平。

公开(公告)号：US20080051812A1

公开(公告)日：2008-02-28

申请号：US11461740

申请日：2006-08-01

申请人： Greg Schmitz ,  Jefferey Bleam ,  Jefffrey L. Bleich ,  Roy Leguidleguid ,  Vahid Saadat

发明人： Greg Schmitz ,  Jefferey Bleam ,  Jefffrey L. Bleich ,  Roy Leguidleguid ,  Vahid Saadat

IPC分类号： A61B17/32

CPC分类号： A61B17/320016 ,  A61B17/1604 ,  A61B17/1611 ,  A61B17/1671 ,  A61B2017/003 ,  A61B2017/32004 ,  A61B2017/320069 ,  A61B2017/32007

摘要： A device for cutting tissue in a human body may include an elongate, hollow shaft having a proximal portion and a distal portion, a bundle of flexible wires slidably disposed within at least a portion of the shaft and having a proximal end and a distal end, and an actuator coupled with the proximal portion of the shaft and the proximal end of the bundle of wires. The distal end of the bundle may be configured to facilitate cutting of tissue, and the wires of the bundle may be at least partially free to move, relative to one another, to allow a cross-sectional shape of the bundle to differ along a length from the proximal to the distal end. The actuator may be configured to move the wires back and forth through the hollow shaft to cause the distal ends of the wires to cut tissue.

摘要翻译： 用于在人体中切割组织的装置可以包括具有近端部分和远侧部分的细长的中空轴，可滑动地设置在所述轴的至少一部分内并具有近端和远端的柔性线束， 以及与所述轴的近侧部分和所述电线束的近端耦合的致动器。 束的远端可以被配置为便于切割组织，并且束的线可以至少部分地相对于彼此自由移动，以允许束的横截面形状沿长度方向不同 从近端到远端。 致动器可以被配置为通过空心轴来回移动电线，以使电线的远端切割组织。

公开(公告)号：US20070287886A1

公开(公告)日：2007-12-13

申请号：US11687597

申请日：2007-03-16

申请人： Vahid Saadat

发明人： Vahid Saadat

IPC分类号： A61B1/04

CPC分类号： A61B1/005 ,  A61B1/0008 ,  A61B1/00082 ,  A61B1/00085 ,  A61B1/00089 ,  A61B1/015 ,  A61B1/018 ,  A61B1/04 ,  A61B5/0031 ,  A61B5/02007 ,  A61B5/6882 ,  A61B8/12 ,  A61B8/445 ,  A61B2018/0212

摘要： Tissue visualization and manipulation systems are described herein. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for treating the tissue region of interest.

摘要翻译： 本文描述了组织可视化和操纵系统。 这样的系统可以包括部署导管和可展开成扩展配置的附接成像罩。 在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。 半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。 此外，任何数量的治疗工具也可以通过展开导管并进入成像罩以用于治疗感兴趣的组织区域。

公开(公告)号：US20070286440A1

公开(公告)日：2007-12-13

申请号：US11754823

申请日：2007-05-29

申请人： Amir Abolfathi ,  Vahid Saadat ,  Loc Phan

发明人： Amir Abolfathi ,  Vahid Saadat ,  Loc Phan

IPC分类号： H04R25/00

CPC分类号： H04R25/606 ,  A61C5/00 ,  A61C8/0093 ,  A61C8/0098 ,  B33Y70/00 ,  B33Y80/00 ,  H04R1/46 ,  H04R3/04 ,  H04R25/554 ,  H04R25/602 ,  H04R25/604 ,  H04R2225/31 ,  H04R2225/67 ,  H04R2420/07 ,  H04R2460/01 ,  H04R2460/13

摘要： Methods and apparatus for transmitting vibrations via an electronic and/or transducer assembly through a tooth or teeth are disclosed herein. The assembly may be attached, adhered, or otherwise embedded into or upon a removable oral appliance to form a hearing aid assembly. Such an oral appliance may be a custom-made device. The electronic and transducer assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating transducer element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure.

摘要翻译： 本文公开了通过电子和/或换能器组件通过齿或齿传递振动的方法和装置。 组件可以附接，粘附或以其它方式嵌入到可移除的口腔器具中或之上，以形成助听器组件。 这种口腔器具可以是定制的装置。 电子和换能器组件可以直接或通过接收器接收输入声音，以处理和放大信号，并经由耦合到牙齿或其它骨结构（例如上颌骨，下颌骨或腭骨）的振动换能器元件传送经处理的声音 结构体。

公开(公告)号：US20070079924A1

公开(公告)日：2007-04-12

申请号：US11245538

申请日：2005-10-06

申请人： Vahid Saadat ,  Arvin Chang

发明人： Vahid Saadat ,  Arvin Chang

IPC分类号： B32B37/00

CPC分类号： B29C53/50 ,  A61B1/0011 ,  A61B1/00142 ,  A61B1/31 ,  B29C53/82 ,  B29C65/16 ,  B29C65/18 ,  B29C65/224 ,  B29C65/48 ,  B29C65/5042 ,  B29C65/5092 ,  B29C65/7847 ,  B29C66/1122 ,  B29C66/1142 ,  B29C66/14 ,  B29C66/4322 ,  B29C66/49 ,  B29C66/61 ,  B29C66/63 ,  B29C66/632 ,  B29C66/71 ,  B29C66/8122 ,  B29C66/81821 ,  B29C66/81871 ,  B29C66/8322 ,  B29C66/83411 ,  B29C66/83413 ,  B29C66/836 ,  B29C2793/009 ,  B29K2995/0092 ,  B29L2031/753 ,  Y10T156/1013 ,  Y10T156/1038 ,  Y10T428/13 ,  B29K2909/02

摘要： Flexible tubular liner coating systems are described herein. A method for coating and forming the flexible tubular inner liner may comprise, in one example, coating at least a first surface of a flexible elongate strip having a first and a second edge and then bringing the first and second edges of the flexible elongate strip into proximity of one another. Once the edges are brought towards one another, they may be joined such that a flexible tubular liner is formed having the coated first surface formed as an inner surface of the flexible tubular liner. Flexible tubular liner coating systems are described herein. A method for coating and forming the flexible tubular inner liner may comprise, in one example, coating at least a first surface of a flexible elongate strip having a first and a second edge and then bringing the first and second edges of the flexible elongate strip into proximity of one another. Once the edges are brought towards one another, they may be joined such that a flexible tubular liner is formed having the coated first surface formed as an inner surface of the flexible tubular liner.

摘要翻译： 本文描述了柔性管状衬里涂覆系统。 在一个实例中，涂覆和形成柔性管状内衬的方法可以包括具有第一和第二边缘的柔性细长带的至少第一表面，然后将柔性细长带的第一和第二边缘带入 彼此接近。 一旦边缘彼此接合，它们可以被接合，使得形成柔性管状衬垫，其具有形成为柔性管状衬垫的内表面的涂覆的第一表面。 本文描述了柔性管状衬里涂覆系统。 在一个实例中，涂覆和形成柔性管状内衬的方法可以包括具有第一和第二边缘的柔性细长带的至少第一表面，然后将柔性细长带的第一和第二边缘带入 彼此接近。 一旦边缘彼此接合，它们可以被接合，使得形成柔性管状衬垫，其具有形成为柔性管状衬垫的内表面的涂覆的第一表面。

公开(公告)号：US07160312B2

公开(公告)日：2007-01-09

申请号：US10288619

申请日：2002-11-04

申请人： Vahid Saadat

发明人： Vahid Saadat

IPC分类号： A61B17/08

CPC分类号： A61L31/16 ,  A61B5/1076 ,  A61B5/4238 ,  A61B8/12 ,  A61B17/0401 ,  A61B17/0487 ,  A61B17/1114 ,  A61B17/29 ,  A61B18/00 ,  A61B18/1442 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/24 ,  A61B90/39 ,  A61B2017/00004 ,  A61B2017/00084 ,  A61B2017/00243 ,  A61B2017/00557 ,  A61B2017/00867 ,  A61B2017/0409 ,  A61B2017/0427 ,  A61B2017/081 ,  A61B2017/1103 ,  A61B2017/1142 ,  A61B2017/2926 ,  A61B2017/2945 ,  A61B2018/00023 ,  A61B2018/00083 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00232 ,  A61B2018/00273 ,  A61B2018/00369 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1432 ,  A61B2018/1435 ,  A61B2090/064 ,  A61F5/0086 ,  A61M29/02 ,  A61N7/00 ,  A61N7/02

摘要： Apparatus and methods are provided for partitioning a gastro-intestinal lumen by intraluminally reducing a local cross-sectional area thereof. The apparatus comprises a plurality of anchors adapted for intraluminal penetration into a wall of the gastro-intestinal lumen to prevent migration or dislodgement of the apparatus, and a partition, which may include a drawstring or a toroidal balloon, coupled to the plurality of anchors to provide a local reduction in the cross-sectional area of the gastro-intestinal lumen.

摘要翻译： 提供了用于通过内部地减少其局部横截面面积来分割胃肠腔的装置和方法。 所述装置包括多个适于管腔内穿入胃肠腔壁的锚固件，以防止装置的移动或移动，以及可包括与多个锚固件相连接的束带或环形气囊的隔板 提供胃肠腔的横截面积的局部减小。

公开(公告)号：US20060253114A1

公开(公告)日：2006-11-09

申请号：US10494487

申请日：2002-11-01

申请人： Vahid Saadat

发明人： Vahid Saadat

IPC分类号： A61B18/02

CPC分类号： A61B18/02 ,  A61B2017/00292 ,  A61B2017/00867 ,  A61B2017/22001 ,  A61B2017/22038 ,  A61B2017/22051 ,  A61B2018/00101 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262

摘要： Methods and apparatus for cryo-therapy are disclosed herein. This includes a hollow guidewire disposed within a catheter having helical loops contacting tissue. A coolant delivery tube disposed within can have a coolant delivered from a proximal end into the guidewire lumen. The coolant flows back proximally through the guidewire while cooling the guidewire surface and cooling or cryogenically ablating the contacting tissue. To minimize guidewire exposure to surrounding fluids or tissue, insulative barriers can be attached to the guidewire. A coolant delivery tube and return lumen can be integrated from a single extrusion in various configurations. Expandable balloons can also be used to expand the loops of the guidewire to contact the tissue. Also, helical loops with a coolant delivery tube or stem disposed longitudinally within the loops can be used and the loops can also have a variable collapsible cooling region.

公开(公告)号：US20060100480A1

公开(公告)日：2006-05-11

申请号：US11311999

申请日：2005-12-19

申请人： Richard Ewers ,  Boris Reydel ,  Eugene Chen ,  Vahid Saadat

发明人： Richard Ewers ,  Boris Reydel ,  Eugene Chen ,  Vahid Saadat

IPC分类号： A61B1/00

CPC分类号： A61B1/00149 ,  A61B1/00082 ,  A61B1/00147 ,  A61B1/31

摘要： The present invention provides methods and apparatus for pleating at least a portion of a patient's body lumen, such as the colon. Pleating is achieved via relative motion between an endoscope and a flexible conduit having an engagement element configured to reversibly engage the body lumen.

摘要翻译： 本发明提供了用于打褶患者体腔（如结肠）的至少一部分的方法和装置。 褶皱通过内窥镜和具有配置为可逆地接合体腔的接合元件的柔性导管之间的相对运动来实现。

公开(公告)号：US20060020276A1

公开(公告)日：2006-01-26

申请号：US10898683

申请日：2004-07-23

申请人： Vahid Saadat ,  Desmond Birkett

发明人： Vahid Saadat ,  Desmond Birkett

IPC分类号： A61B17/08

CPC分类号： A61B17/0401 ,  A61B17/08 ,  A61B18/1492 ,  A61B2017/0417 ,  A61B2017/0454 ,  A61B2017/0458 ,  A61B2017/0464 ,  A61B2017/081 ,  A61B2018/00291

摘要： Apparatus and methods are provided for achieving prolonged maintenance of gastrointestinal (“GI”) tissue folds. The apparatus and methods are adapted to form, secure, approximate and promote healing of tissue folds. Such healing may comprise remodeling the tissue folds along region(s) of opposing tissue contact to facilitate prolonged maintenance of the folds. In one variation, the apparatus and methods may be utilized to achieve gastric reduction. The apparatus may be provided as a system of tools.

摘要翻译： 提供了用于实现胃肠（“GI”）组织折叠的延长维持的装置和方法。 该装置和方法适于形成，固定，近似和促进组织折叠的愈合。 这种愈合可以包括沿着相对的组织接触区域重塑组织褶皱，以便于折叠的延长维持。 在一个变型中，可以利用该装置和方法来实现胃的减少。 该装置可以被提供为工具系统。