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21.发明授权公开(公告)号：US06264892B1
公开(公告)日：2001-07-24
申请号：US09480922
申请日：2000-01-11
IPC分类号： G01N2726
CPC分类号： G01N30/6095 , B01L3/502707 , B01L3/502715 , B01L3/5055 , B01L7/54 , B01L2200/025 , B01L2200/0689 , B01L2200/10 , B01L2200/12 , B01L2300/0816 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2300/1822 , B01L2400/0415 , B29C65/02 , B29C66/54 , B29C66/549 , B29L2031/756 , G01N27/44704 , G01N27/44708 , G01N27/44721 , G01N27/44773 , G01N27/44791 , G01N30/02 , G01N30/60 , G01N30/6047 , G01N30/6052 , G01N30/606 , G01N2030/285 , G01N2030/3007 , G01N2030/3015 , G01N2030/303 , Y10T156/1064 , G01N2030/0035
摘要： Miniaturized planar column devices for use in a liquid phase separation apparatus are described. The devices include microstructures that have been fabricated by laser ablation in a variety of novel support substrates. Devices formed according to the methods of the invention include associated laser-ablated features required for function, such as on-device reservoirs or makeup flow compartments, analyte detection means and sample injection means. The miniaturized columns can be used in an apparatus intended for analysis of either small and/or macromolecular solutes in the liquid phase which employs chromatographic, electrophoretic or electrochromatographic separation means. The apparatus can include a variety of optional injection means, manifolds, keeper means, post column collection means, and combinations thereof.
摘要翻译： 描述了用于液相分离装置的微型平面柱装置。 这些器件包括通过在各种新型支撑衬底中的激光烧蚀制造的微结构。 根据本发明的方法形成的器件包括功能所需的相关的激光烧蚀特征，例如器件上储存器或补充流动隔室，分析物检测装置和样品注入装置。 小型化柱可用于用于分析液相中的小分子和/或大分子溶质的装置，其使用色谱，电泳或电色谱分离装置。 该装置可以包括各种可选的注射装置，歧管，保持装置，柱后收集装置及其组合。
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22.发明授权
公开(公告)号：US6033628A
公开(公告)日：2000-03-07
申请号：US656281
申请日：1998-04-27
IPC分类号： B01D15/08 , B01L3/00 , B01L7/00 , B29C65/02 , B81B1/00 , B81C1/00 , G01N27/447 , G01N30/02 , G01N30/28 , G01N30/30 , G01N30/60 , G01N37/00 , G01N27/26 , G01N30/00 , G01N33/50
CPC分类号： G01N30/6095 , B01L3/502707 , B01L7/54 , G01N27/44704 , G01N27/44708 , G01N27/44773 , G01N27/44791 , B01L2200/025 , B01L2200/0689 , B01L2200/10 , B01L2200/12 , B01L2300/0816 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2300/1822 , B01L2400/0415 , B01L3/502715 , B01L3/5055 , B29C65/02 , B29C66/54 , B29C66/549 , B29L2031/756 , G01N2030/285 , G01N2030/3007 , G01N2030/3015 , G01N2030/303 , G01N27/44721 , G01N30/02 , G01N30/60 , G01N30/6047 , G01N30/6052 , G01N30/606 , Y10T156/1064
摘要： In a method of forming a microchannel and/or microcavity structure by bonding together two elements (1, 2) having opposed plane surfaces of the same or different material, one or both surfaces having open channels and/or cavities, bonding is effected by applying to one or both element surfaces (1, 2) a thin layer (3) of a solution of a material capable of fusing with and having a lower melting point than that of the material or materials of the two element surfaces (1, 2) in a solvent which substantially does not dissolve the element surface material or materials. The solvent is then removed, and the two elements (1, 2) are brought together and heated to a temperature where the dissolved material is caused to melt but not the element surface material or materials.
摘要翻译： PCT No.PCT / US95 / 13365 Sec。 371日期：1998年4月27日 102（e）日期1998年4月27日PCT提交1995年10月16日PCT公布。 公开号WO96 / 12546 日期：1996年5月2日在通过将具有相同或不同材料的相对平面的两个元件（1,2）结合在一起形成微通道和/或微腔结构的方法中，一个或两个表面具有开放的通道和/或腔， 通过向一个或两个元件表面（1,2）施加能够熔化并且具有比两个元件表面的材料或材料的熔点低的材料的溶液的薄层（1） 1,2）在基本上不溶解元件表面材料或材料的溶剂中。 然后除去溶剂，将两个元件（1,2）放在一起并加热至使溶解的材料熔化而不是元件表面材料或材料的温度。
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23.发明授权Miniaturized planar columns in novel support media for liquid phase analysis 失效用于液相分析的新颖载体介质中的小型平面柱
公开(公告)号：US5658413A
公开(公告)日：1997-08-19
申请号：US482245
申请日：1995-06-07
IPC分类号： B01D15/08 , B01L3/00 , B01L7/00 , B29C65/02 , B81B1/00 , B81C1/00 , G01N27/447 , G01N30/02 , G01N30/28 , G01N30/30 , G01N30/60 , G01N37/00 , B32B31/00
CPC分类号： G01N30/6095 , B01L3/502707 , B01L7/54 , G01N27/44704 , G01N27/44708 , G01N27/44773 , G01N27/44791 , B01L2200/025 , B01L2200/0689 , B01L2200/10 , B01L2200/12 , B01L2300/0816 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2300/1822 , B01L2400/0415 , B01L3/502715 , B01L3/5055 , B29C65/02 , B29C66/54 , B29C66/549 , B29L2031/756 , G01N2030/285 , G01N2030/3007 , G01N2030/3015 , G01N2030/303 , G01N27/44721 , G01N30/02 , G01N30/60 , G01N30/6047 , G01N30/6052 , G01N30/606 , Y10T156/1064
摘要： Miniaturized planar column devices are described for use in liquid phase analysis, the devices comprising microstructures fabricated by laser ablation in a variety of novel support substrates. Devices formed according to the invention include associated laser-ablated features required for function, such as analyte detection means and fluid communication means. Miniaturized columns constructed under the invention find use in any analysis system performed on either small and/or macromolecular solutes in the liquid phase and may employ chromatographic, electrophoretic, electrochromatographic separation means, or any combination thereof.
摘要翻译： 描述了用于液相分析的微型平面柱装置，该装置包括通过在各种新型支撑衬底中的激光烧蚀制造的微结构。 根据本发明形成的装置包括功能所需的相关的激光烧蚀特征，例如分析物检测装置和流体连通装置。 根据本发明构造的微型柱可用于在液相中的小分子和/或大分子溶质上进行的任何分析系统，并且可以使用色谱，电泳，电色谱分离装置或其任何组合。
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公开(公告)号：US5305015A
公开(公告)日：1994-04-19
申请号：US864889
申请日：1992-04-02
申请人： Christopher A. Schantz , Eric G. Hanson , Si-Ty Lam , Paul H. McClelland , William J. Lloyd , Laurie S. Mittelstadt , Alfred I. Tsong Pan
发明人： Christopher A. Schantz , Eric G. Hanson , Si-Ty Lam , Paul H. McClelland , William J. Lloyd , Laurie S. Mittelstadt , Alfred I. Tsong Pan
CPC分类号： B41J2/1623 , B41J2/14024 , B41J2/14072 , B41J2/155 , B41J2/162 , B41J2/1628 , B41J2/1631 , B41J2/1634 , B41J2/1643 , B41J2002/14387 , B41J2202/19 , B41J2202/20 , Y10T29/49401
摘要： In one of the preferred embodiments, an inkjet printhead includes a nozzle member formed of a polymer material that has been laser-ablated to form tapered inkjet orifices. The nozzle member is then mounted to a substrate containing heating elements, each heating element being associated with a single orifice. In a preferred method, the orifices are formed by Excimer laser ablation.In other aspects of the invention, vaporization chambers as well as ink channels, providing fluid communication between an ink reservoir and the orifices, are also formed by Excimer laser ablation.
摘要翻译： 在一个优选实施例中，喷墨打印头包括由激光烧蚀以形成锥形喷墨孔的聚合物材料形成的喷嘴构件。 然后将喷嘴构件安装到包含加热元件的基板上，每个加热元件与单个孔口相关联。 在优选的方法中，孔通过准分子激光烧蚀形成。 在本发明的其它方面，还通过准分子激光烧蚀形成了在油墨储存器和孔之间提供流体连通的蒸发室以及油墨通道。
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