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20 条记录 (耗时 0.019 秒)

    Method and apparatus for measuring a low power signal
    1.
    发明授权
    Method and apparatus for measuring a low power signal 有权
    用于测量低功率信号的方法和装置

    公开(公告)号：US06660991B2

    公开(公告)日：2003-12-09

    申请号：US10095235

    申请日：2002-03-11

    申请人： Volker Brombacher ,  Fritz Bek

    发明人： Volker Brombacher ,  Fritz Bek

    IPC分类号： H01J4014

    CPC分类号： H03M3/00 ,  G01J1/46

    摘要： Low intensity light is incident upon a photodiode whose output is coupled to an integrator. The output of the integrator is coupled to an input of an A/D converter, whose output is coupled to a microprocessor, whose output is coupled to a filter. A second output of the microprocessor is coupled to a gate electrode of a FET to provide a reset signal to the FET to reset the integrator. The microprocessor compares the digital samples of the integrated signal from the A/D converter and, firstly, generates the reset signal if a sample is beyond a set limit, and, secondly, calculates delta values between adjacent samples and interpolates the delta values for the reset periods so as to provide a continuous data stream which can be filtered by a filter matched to the form of the original signal.

    摘要翻译： 低强度光入射到其输出耦合到积分器的光电二极管上。 积分器的输出耦合到A / D转换器的输入，其输出耦合到微处理器，其输出耦合到滤波器。 微处理器的第二输出耦合到FET的栅电极，以向FET提供复位信号以复位积分器。 微处理器将来自A / D转换器的积分信号的数字样本进行比较，首先如果样本超出设定极限，则产生复位信号，其次，计算相邻样本之间的增量值，并对 复位周期，以便提供连续的数据流，该数据流可以由与原始信号的形式匹配的滤波器进行滤波。

    Mixing liquids using electroosmotic flow
    2.
    发明授权
    Mixing liquids using electroosmotic flow 失效
    使用电渗流混合液体

    公开(公告)号：US5785831A

    公开(公告)日：1998-07-28

    申请号：US598717

    申请日：1996-02-08

    申请人： Fritz Bek

    发明人： Fritz Bek

    IPC分类号： G01N1/36 ,  B01F3/08 ,  B01F5/00 ,  B01F5/04 ,  B01F13/00 ,  B01F15/04 ,  B01L3/00 ,  G01N27/447 ,  G01N30/02 ,  G01N30/28 ,  G01N30/34 ,  G01N37/00 ,  G05D11/03 ,  G01N27/26

    CPC分类号： B01F13/0076 ,  B01F13/0001 ,  B01F15/0412 ,  B01F5/0403 ,  B01L3/50273 ,  G01N27/44704 ,  G01N30/34 ,  G05D11/03 ,  B01F2215/0037 ,  B01L2300/0867 ,  B01L2400/0418 ,  G01N2030/027 ,  G01N2030/285 ,  G01N2030/347

    摘要： A method and apparatus for mixing liquids using electroosmotic flow. Multiple capillaries (100, 104, 106) or microchip channels meet at a common junction (102). One capillary (100) is used for mixed liquids and each of the remaining capillaries (104, 106) are used for supplying a liquid (112, 114) to be mixed. Each of the supply capillaries (104, 106) has a free end that is immersed into a vial (108, 110) of liquid (112, 114). A first power supply terminal (112) is attached to a free end of the mixed liquid capillary (100). The liquid in each vial has an electrode that is switchably connected to a second power supply terminal. Closing a switch (116, 118) causes liquid to flow from a vial through the common junction and through the mixed liquid capillary. Each switch is independent and each may be closed continuously, switched at a constant duty cycle, or switched at a variable duty cycle. As a result, continuous mixing or variable ratio mixing may be achieved.

    摘要翻译： 一种使用电渗流混合液体的方法和装置。 多个毛细管（100,104,106）或微芯片通道在公共接点处相遇（102）。 一个毛细管（100）用于混合液体，并且每个剩余的毛细管（104,106）用于供应要混合的液体（112,114）。 每个供应毛细管（104,106）具有浸入液体（112,114）的小瓶（108,110）中的自由端。 第一电源端子（112）附接到混合液体毛细管（100）的自由端。 每个小瓶中的液体具有可切换地连接到第二电源端子的电极。 关闭开关（116,118）使液体从小瓶流过公共接头并通过混合液体毛细管。 每个开关是独立的，每个开关可以连续闭合，以恒定的占空比切换，或以可变的占空比进行切换。 结果，可以实现连续混合或可变比混合。

    Low voltage miniaturized column analytical apparatus and method
    3.
    发明授权
    Low voltage miniaturized column analytical apparatus and method 失效
    低压小型化柱分析仪和方法

    公开(公告)号：US5645702A

    公开(公告)日：1997-07-08

    申请号：US483217

    申请日：1995-06-07

    申请人： Klaus E. Witt ,  Patrick Kaltenbach ,  Fritz Bek ,  Sally A. Swedberg ,  Laurie S. Mittelstadt

    发明人： Klaus E. Witt ,  Patrick Kaltenbach ,  Fritz Bek ,  Sally A. Swedberg ,  Laurie S. Mittelstadt

    IPC分类号： G01N27/447 ,  G01N30/02 ,  G01N30/60 ,  G01N27/26

    CPC分类号： G01N27/44773 ,  G01N30/02 ,  G01N30/60

    摘要： A miniaturized column analytical apparatus having a miniaturized column device containing a body with an elongate separation compartment is provided. Two or more sets of spaced apart antennas are positioned along the elongate separation compartment. The elongate separation compartment has first and second opposing sides along its elongate dimension. Each set of antenna contains a plurality of antennas. One antenna from each set is associated with at least one antenna from each of the other sets to form repeating sequences of antennas along the separation compartment on the opposing sides of the separation compartment. Each set of the antennas is associated with a different oscillating electrical potential to provide a plurality of oscillating electric fields along the elongate separation compartment to draw a target substance along the elongate separation compartment toward an exit end of the separation compartment. The detector can detect a target substance passing out of the elongate separation compartment.

    摘要翻译： 提供了一种小型化的柱分析装置，其具有包含具有细长隔离室的主体的小型化柱装置。 两个或更多组间隔开的天线沿着细长分隔室定位。 细长分离隔室具有沿其细长尺寸的第一和第二相对侧。 每组天线包含多个天线。 每组中的一个天线与至少一个其他组中的一个天线相关联，以在分隔室的相对侧上沿分隔室形成重复的天线序列。 每组天线与不同的振荡电势相关联，以沿着细长分隔室提供多个振荡电场，以沿着细长隔离室将目标物质拉向分离室的出口端。 检测器可以检测出从细长隔离室流出的目标物质。

    FLUID FLOW CONTROL IN A MICROFLUIDIC DEVICE
    4.
    发明申请
    FLUID FLOW CONTROL IN A MICROFLUIDIC DEVICE 审中-公开
    微流控器件中的流体流量控制

    公开(公告)号：US20110290330A1

    公开(公告)日：2011-12-01

    申请号：US12672653

    申请日：2007-08-09

    申请人： Marcus Gassmann ,  Fritz Bek

    发明人： Marcus Gassmann ,  Fritz Bek

    IPC分类号： F15D1/00

    CPC分类号： B01L3/502761 ,  B01L3/502738 ,  B01L2200/0621 ,  B01L2200/0668 ,  B01L2200/0673 ,  B01L2200/146 ,  B01L2300/0816 ,  B01L2300/0861 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/043 ,  B01L2400/0487 ,  B01L2400/0688 ,  Y10T137/0396

    摘要： A method for removing fluid in a microfluidic device, the microfluidic device having a fluid channel, a first well, and a second well, the first well and the second well being coupled to a first end of the fluid channel, the method including applying a pressure difference between the second well and the first well, and applying a pressure difference between the first end and a second end of the fluid channel being below a certain threshold, for at least partly removing a first fluid from a first supply line coupled between the first well and the first end of the fluid channel.

    摘要翻译： 一种用于去除微流体装置中的流体的方法，所述微流体装置具有流体通道，第一阱和第二阱，所述第一阱和所述第二阱耦合到所述流体通道的第一端，所述方法包括施加 第二井和第一井之间的压力差，以及将流体通道的第一端和第二端之间的压差施加在一定阈值以下，以至少部分地从耦合在第二井和第二井之间的第一供应管线去除第一流体 第一井和流体通道的第一端。

    Droplet-based fluidic coupling
    8.
    发明申请
    Droplet-based fluidic coupling 审中-公开
    基于液滴的流体耦合

    公开(公告)号：US20080311006A1

    公开(公告)日：2008-12-18

    申请号：US11897225

    申请日：2007-08-29

    申请人： Fritz Bek ,  Marcus Gassmann

    发明人： Fritz Bek ,  Marcus Gassmann

    IPC分类号： B01L3/00 ,  G01N1/10

    CPC分类号： G01N35/1081 ,  B01L3/0262 ,  B01L3/0293 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2300/0816 ,  B01L2400/0421 ,  B01L2400/0478 ,  G01N2035/1039 ,  Y10T436/2575

    摘要： A fluid supply unit is described, with the fluid supply unit comprising a fluid dispenser with an orifice adapted for dispensing a fluid, and a microfluidic device comprising an inlet port located at one of the faces of the microfluidic device. The fluid supply unit is adapted for establishing a fluidic contact between a droplet formed at the fluid dispenser's orifice and an inlet port of the microfluidic device, and the fluid supply unit is adapted for electrophoretically moving charged compounds from the droplet towards the inlet port.

    摘要翻译： 描述了流体供应单元，其中流体供应单元包括具有适于分配流体的孔的流体分配器，以及包括位于微流体装置的一个面处的入口的微流体装置。 流体供应单元适于在流体分配器的孔口处形成的液滴和微流体装置的入口之间建立流体接触，并且流体供应单元适于将带电荷的化合物从液滴电泳移动到入口端口。

    Method and apparatus for measuring a low power signal
    9.
    再颁专利
    Method and apparatus for measuring a low power signal 有权
    用于测量低功率信号的方法和装置

    公开(公告)号：USRE39527E1

    公开(公告)日：2007-03-27

    申请号：US10956015

    申请日：2004-09-30

    申请人： Volker Brombacher ,  Fritz Bek

    发明人： Volker Brombacher ,  Fritz Bek

    IPC分类号： H01J40/14 ,  H03F3/08

    CPC分类号： H03M3/00 ,  G01J1/46

    摘要： Low intensity light is incident upon a photodiode whose output is coupled to an integrator. The output of the integrator is coupled to an input of an A/D converter, whose output is coupled to a microprocessor, whose output is coupled to a filter. A second output of the microprocessor is coupled to a gate electrode of a FET to provide a reset signal to the FET to reset the integrator. The microprocessor compares the digital samples of the integrated signal from the A/D converter and, firstly, generates the reset signal if a sample is beyond a set limit, and, secondly, calculates delta values between adjacent samples and interpolates the delta values for the reset periods so as to provide a continuous data stream which can be filtered by a filter matched to the form of the original signal.

    摘要翻译： 低强度光入射到其输出耦合到积分器的光电二极管上。 积分器的输出耦合到A / D转换器的输入，其输出耦合到微处理器，其输出耦合到滤波器。 微处理器的第二输出耦合到FET的栅电极，以向FET提供复位信号以复位积分器。 微处理器将来自A / D转换器的积分信号的数字样本进行比较，首先如果样本超出设定极限，则产生复位信号，其次，计算相邻样本之间的增量值，并对 复位周期，以便提供连续的数据流，该数据流可以由与原始信号的形式匹配的滤波器进行滤波。

    Fluid injection system
    10.
    发明申请
    Fluid injection system 审中-公开
    流体注射系统

    公开(公告)号：US20070039823A1

    公开(公告)日：2007-02-22

    申请号：US11443524

    申请日：2006-05-30

    申请人： Fritz Bek ,  Marcus Gassmann

    发明人： Fritz Bek ,  Marcus Gassmann

    IPC分类号： C07K1/26 ,  G01N27/00

    CPC分类号： B01L3/502715 ,  B01L3/502784 ,  B01L2200/027 ,  B01L2200/0605 ,  B01L2200/0673 ,  B01L2400/0415 ,  G01N27/44743

    摘要： A microfluidic system comprises a first reservoir, an injection channel fluidically coupled to the first reservoir and to an injection point adapted for injecting an amount of fluid, and a side channel fluidically coupled to the injection channel at an intersection point located between the first reservoir and the injection point, the side channel being fluidically coupled with a second reservoir. Both the injection channel and the side channel are at least partly filled with a first substance and the second reservoir is at least partly filled with a second substance. The first substance is a gel and the second substance is a buffer solution. The side channel's cross section is larger than the injection channel's cross section.

    摘要翻译： 微流体系统包括第一储存器，流体耦合到第一储存器的注入通道和适于注入一定量流体的注入点，以及在位于第一储存器和第一储存器之间的交叉点处与注入通道流体耦合的侧通道 注射点，侧通道与第二储存器流体耦合。 注入通道和侧通道都至少部分地填充有第一物质，并且第二储存器至少部分地填充有第二物质。 第一物质是凝胶，第二物质是缓冲溶液。 侧面通道的横截面大于喷射通道的横截面积。