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132 条记录 (耗时 0.029 秒)

    Process for manufacture of 4-amino-hydroxybutylidene-1,1-bisphosphonic acid and its salts
    21.
    发明申请
    Process for manufacture of 4-amino-hydroxybutylidene-1,1-bisphosphonic acid and its salts 失效
    4-氨基 - 羟基亚丁基-1,1-二膦酸及其盐的制备方法

    公开(公告)号：US20070149486A1

    公开(公告)日：2007-06-28

    申请号：US11645757

    申请日：2006-12-27

    申请人： Ashok Kumar ,  Suneel Dike ,  Avinash Nijasure ,  Vijaya Bhaware

    发明人： Ashok Kumar ,  Suneel Dike ,  Avinash Nijasure ,  Vijaya Bhaware

    IPC分类号： A61K31/675 ,  C07F9/572

    CPC分类号： C07F9/3873

    摘要： The preset invention relates to a cost effective, high yielding, reproducible method for the manufacture of alendronic acid or its salt, such as sodium alendronate, from inexpensive and readily available pyrrolidone using phosphonating agents such as PCl3 in the presence of acids such as sulphonic acids, sulphuric acid or phosphoric acid, and pharmaceutical dosage forms of alendronic acid or pharmaceutically acceptable salts thereof.

    摘要翻译： 本发明涉及一种成本有效，高产率，可重现的方法，用于使用膦酸化剂如PCl 3 N在廉价且易于获得的吡咯烷酮中制备阿仑膦酸或其盐，例如阿仑膦酸钠 存在酸例如磺酸，硫酸或磷酸，以及阿仑膦酸的药物剂型或其药学上可接受的盐。

    Self-healing coatings using microcapsules
    22.
    发明申请
    Self-healing coatings using microcapsules 失效
    使用微胶囊的自愈涂层

    公开(公告)号：US20060042504A1

    公开(公告)日：2006-03-02

    申请号：US10923890

    申请日：2004-08-24

    申请人： Ashok Kumar ,  Larry Stephenson

    发明人： Ashok Kumar ,  Larry Stephenson

    IPC分类号： C04B9/02

    CPC分类号： C09D5/002 ,  C04B20/1037 ,  C04B26/02 ,  C04B2111/00482 ,  C08K9/10 ,  C09D7/40 ,  C09D7/69 ,  Y10T428/2985 ,  C04B22/002 ,  C04B22/064 ,  C04B24/2611 ,  C04B40/0641 ,  C04B40/0675 ,  C04B2103/0075

    摘要： Self-healing coatings incorporate microcapsules of about 60-150 microns diameter that contain film formers and dust suppression compounds suitable for controlling spalling of lead dust, for example. In one embodiment, a primer paint is mixed with these microcapsules and applied by brushing or rolling. After the coating has cured, any physical compromise of the coating results in microcapsules bursting to release liquid that fills and seals the compromised volume. The microcapsule contents protect the underlying substrate from damage and repair some of the outer coating. In one application, embodiments of these self-healing coatings seal existing lead-based paint for suppression of lead dust. In another embodiment, microcapsules are provided separately to enhance commercially available products. For example, if a paint formulation is known a priori, specifically configured microcapsules, packaged separately from the paint and designed for use with the paint formulation, are added to the paint just prior to application.

    摘要翻译： 自修复涂层包含约60-150微米直径的微胶囊，其包含适用于控制铅粉尘剥落的成膜剂和粉尘抑制化合物。 在一个实施方案中，将底漆与这些微胶囊混合并通过刷涂或滚涂进行涂布。 在涂层固化之后，涂层的任何物理损害导致微胶囊破裂以释放填充并密封受损体积的液体。 微胶囊内容物保护底层基材免受损坏并修复一些外涂层。 在一个应用中，这些自修复涂层的实施例密封现有的铅基涂料以抑制铅尘。 在另一个实施方案中，单独提供微胶囊以增强市售产品。 例如，如果涂料配方是已知的，则在施涂前将先前，特别配置的微胶囊与涂料分开包装并设计用于涂料配方，加入到涂料中。

    Expandable coil cathodic protection anode
    24.
    发明授权
    Expandable coil cathodic protection anode 失效
    可扩展线圈阴极保护阳极

    公开(公告)号：US5176807A

    公开(公告)日：1993-01-05

    申请号：US462935

    申请日：1990-01-03

    申请人： Ashok Kumar

    发明人： Ashok Kumar

    IPC分类号： C23F13/08

    CPC分类号： C23F13/16 ,  C23F13/18 ,  F24H9/0047

    摘要： A cathodic protection system for a tank has an anode which comprises a long extendible coil of wire of a valve metal coated with a suitable electrically conductive ceramic material. The coil provides reduced electrolyte resistance and power consumption. At installation the coil is extended to provide the anode length desired for the particular tank. Each end of the anode can have insulation to provide the desired dielectric standoff. The insulation of the lower end can be in the form of a the weighted element to stabilize the position of the anode.

    摘要翻译： 用于罐的阴极保护系统具有阳极，该阳极包括涂覆有合适的导电陶瓷材料的阀金属的长延伸线的线。 线圈提供降低的电解质电阻和功耗。 在安装时，线圈被延伸以提供特定罐所需的阳极长度。 阳极的每个端部可以具有绝缘以提供期望的电介质隔离。 下端的绝缘体可以是加权元件的形式，以稳定阳极的位置。

    Non-inverting high speed low level gate to Schottky transistor-transistor logic translator
    25.
    发明授权
    Non-inverting high speed low level gate to Schottky transistor-transistor logic translator 失效
    同相高速低电平门到肖特基晶体管 - 晶体管逻辑转换器

    公开(公告)号：US4607175A

    公开(公告)日：1986-08-19

    申请号：US644833

    申请日：1984-08-27

    申请人： Gil S. Lee ,  Ashok Kumar

    发明人： Gil S. Lee ,  Ashok Kumar

    IPC分类号： H03K19/0175 ,  H03K19/013 ,  H03K19/018 ,  H03K19/082 ,  H03K19/088 ,  G01R31/28 ,  H03K19/003 ,  H03K19/092

    CPC分类号： H03K19/0826 ,  H03K19/01806

    摘要： A non-inverting high speed low level gate to Schottky transistor logic translator circuit includes a first input circuit adapted for receiving a first input signal and having its outputs connected to a first node and a second node. A first Schottky transistor is provided which has its base connected to the first node and to a voltage supply potential via a first resistor, its emitter connected to the second node and its collector connected to a third node and to the supply potential via a second resistor. A second Schottky transistor is provided which has its base coupled to the third node, its collector connected to the supply potential via a third resistor and its emitter connected to a fourth node. An upper output transistor has its base connected to the fourth node and to a ground potential via a fourth resistor, its collector connected to the supply potential via a fifth resistor and its emitter connected to an output circuit terminal. A lower output transistor has its base connected to the second node, its collector connected to the output circuit terminal and its emitter connected to the ground potential. Second and third circuits formed of low level NAND gates are adapted for receiving test input signals and have their outputs connected to the first and second nodes for testing purposes. A fourth input circuit formed of low level NAND gates is adapted for receiving a second input signal and has its outputs connected to the second node and the third node for turning off the lower output and upper output transistors so as to maintain the output circuit terminal in high impedance state.

    摘要翻译： 非反相高速低电平门对肖特基晶体管逻辑转换器电路包括适于接收第一输入信号并使其输出连接到第一节点和第二节点的第一输入电路。 提供第一肖特基晶体管，其基极通过第一电阻器连接到第一节点和电压供应电位，其发射极连接到第二节点并且其集电极连接到第三节点并经由第二电阻器连接到电源电位 。 提供第二肖特基晶体管，其基极耦合到第三节点，其集电极经由第三电阻器连接到电源电位，其发射极连接到第四节点。 上输出晶体管的基极通过第四电阻连接到第四节点并接地，其集电极通过第五电阻连接到电源电位，其发射极连接到输出电路端。 低输出晶体管的基极连接到第二节点，其集电极连接到输出电路端子，其发射极连接到地电位。 由低电平NAND门形成的第二和第三电路适于接收测试输入信号，并将其输出连接到第一和第二节点用于测试目的。 由低电平NAND门形成的第四输入电路适于接收第二输入信号，并且其输出连接到第二节点和第三节点，用于关闭下输出和上输出晶体管，以便将输出电路端子保持在 高阻态。

    DNA biochip and methods of use
    27.
    发明授权
    DNA biochip and methods of use 有权
    DNA生物芯片和使用方法

    公开(公告)号：US08916343B2

    公开(公告)日：2014-12-23

    申请号：US12931116

    申请日：2011-01-24

    申请人： Arun Kumar ,  Ashok Kumar ,  Shree R. Singh ,  Souheil Zekri

    发明人： Arun Kumar ,  Ashok Kumar ,  Shree R. Singh ,  Souheil Zekri

    IPC分类号： C12Q1/68 ,  C12M1/36 ,  G01N15/06 ,  C07H21/04 ,  G01N33/569 ,  G01N33/53

    CPC分类号： G01N33/56983 ,  C12Q1/6825 ,  C12Q1/6837 ,  G01N33/5308 ,  C12Q2527/125 ,  C12Q2565/501 ,  C12Q2565/607

    摘要： The subject invention concerns materials and methods for detecting nucleic acid sequences. One aspect of the invention concerns a silicon-based “biochip” comprising nucleic acid immobilized thereon. In one embodiment, the silicon comprises microcavities. The nucleic acid to be assayed for the presence of one or more target nucleic acid sequences is immobilized on the silicon. A nucleic acid, such as an oligonucleotide probe, having a sequence substantially complementary to the target nucleic acid sequence can be used to detect the immobilized nucleic acid on the silicon. If the nucleic acid used for detection hybridizes with a target nucleic acid sequence, the hybridized sequences can be detected directly or indirectly. In an exemplified embodiment, the oligonucleotide probe can be labeled with a detectable label, for example, a fluorescent molecule. The subject invention also concerns methods for detecting a target nucleic acid using a silicon-based biochip of the invention.

    摘要翻译： 本发明涉及用于检测核酸序列的材料和方法。 本发明的一个方面涉及包含固定在其上的核酸的硅基“生物芯片”。 在一个实施例中，硅包括微腔。 要测定的一种或多种靶核酸序列的存在的核酸被固定在硅上。 可以使用具有与靶核酸序列基本上互补的序列的核酸，例如寡核苷酸探针，以检测硅上的固定化核酸。 如果用于检测的核酸与靶核酸序列杂交，则可以直接或间接检测杂交的序列。 在示例性实施方案中，寡核苷酸探针可以用可检测标记，例如荧光分子标记。 本发明还涉及使用本发明的硅基生物芯片检测靶核酸的方法。

    Composition and manufacturing processes of a toxicity free botanical drug for curative treatment of chronic diseases
    28.
    发明授权
    Composition and manufacturing processes of a toxicity free botanical drug for curative treatment of chronic diseases 有权
    无毒性植物药物用于治疗慢性疾病的组成和制造过程

    公开(公告)号：US08668938B2

    公开(公告)日：2014-03-11

    申请号：US13575807

    申请日：2010-01-29

    申请人： Ashok Kumar ,  Aditi Kumar ,  Prakrati Kumar ,  Priti Kumar

    发明人： Ashok Kumar ,  Aditi Kumar ,  Prakrati Kumar ,  Priti Kumar

    IPC分类号： A01N65/00

    CPC分类号： A61K36/23 ,  A61K36/88 ,  A61K2300/00

    摘要： This invention discloses composition and manufacturing processes of a toxicity free botanical drug formulation for curative treatment of chronic diseases. It is manufactured from plants Crinum asiaticum and Crocus sativus. This drug was administered to human volunteers by oral and intranasal routes in effective amount for an effective time period. Effective amount and effective time of administration varies from one human volunteer to another depending upon age, body weight, length of disease, severity of disease, type of the disease. In vitro experiments show that this botanical drug causes proliferation and differentiation of stem cells.

    摘要翻译： 本发明公开了用于治疗慢性疾病的无毒性植物药物制剂的组合物和制造方法。 它由植物Crinum asiaticum和Crocus sativus制成。 该药物通过口服和鼻内途径以有效的时间段施用于人类志愿者。 根据年龄，体重，疾病长度，疾病的严重程度，疾病的类型，有效量和有效的给药时间因人类志愿者而异。 体外实验表明，这种植物药物引起干细胞的增殖和分化。

    APPLICATION SHORTCUT USER INTERFACE SYSTEMS AND METHODS
    29.
    发明申请
    APPLICATION SHORTCUT USER INTERFACE SYSTEMS AND METHODS 有权
    应用更快的用户界面系统和方法

    公开(公告)号：US20130179833A1

    公开(公告)日：2013-07-11

    申请号：US13343909

    申请日：2012-01-05

    申请人： Heath Stallings ,  Omar Abou-Khamis ,  Nathan J. Maxfield ,  Ashok Kumar ,  Andrien J. Wang ,  Don G. Archer ,  Aravind Perumandla

    发明人： Heath Stallings ,  Omar Abou-Khamis ,  Nathan J. Maxfield ,  Ashok Kumar ,  Andrien J. Wang ,  Don G. Archer ,  Aravind Perumandla

    IPC分类号： G06F3/048

    CPC分类号： G06F3/0482

    摘要： An exemplary method includes a user computing device 1) determining current states, such as current integration states and/or current operational states, of software applications included in a suite of software applications relative to the user computing device, 2) identifying, based on the current states, access options for the software applications included in the suite of software applications, and 3) providing, by the user computing device for display, a graphical user interface that includes the access options configured to be selected by a user of the user computing device to access the software applications included in the suite of software applications. Corresponding methods and systems are also disclosed.

    摘要翻译： 一种示例性方法包括用户计算设备1）确定包括在相对于用户计算设备的软件应用套件中的软件应用的当前状态，例如当前集成状态和/或当前操作状态，2）基于 当前状态，软件应用程序包括的软件应用程序的访问选项，以及3）由用户计算设备提供用于显示的图形用户界面，其包括被配置为由用户计算的用户选择的访问选项 设备访问软件应用程序套件中包含的软件应用程序。 还公开了相应的方法和系统。