公开(公告)号：US12295711B2

公开(公告)日：2025-05-13

申请号：US18100610

申请日：2023-01-24

Applicant: Medtronic MiniMed, Inc.

Inventor： Andrea Varsavsky ,  Fei Yu ,  Ning Yang

IPC: A61B5/0537 ,  A61B5/00 ,  A61B5/0538 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61M5/142 ,  A61M5/158 ,  A61M5/172 ,  G01N27/02

Abstract: Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.

公开(公告)号：US12239443B2

公开(公告)日：2025-03-04

申请号：US17571723

申请日：2022-01-10

Applicant: Medtronic MiniMed, Inc.

Inventor： Ning Yang ,  Raghavendhar Gautham ,  Bradley C. Liang ,  Rajiv Shah

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/145 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/1486 ,  A61M5/142 ,  A61M5/158 ,  A61M5/172 ,  G01N27/02 ,  G01N27/416 ,  G01N33/49 ,  G01N33/66 ,  G01N33/96 ,  G01R35/00 ,  G08B21/18

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

公开(公告)号：US12082929B2

公开(公告)日：2024-09-10

申请号：US17135766

申请日：2020-12-28

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Ning Yang ,  Raghavendhar Gautham ,  Rajiv Shah

IPC: A61B5/1495 ,  A61B5/00 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/145 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/1486 ,  A61M5/142 ,  A61M5/158 ,  A61M5/172 ,  G01N27/02 ,  G01N27/416 ,  G01N33/49 ,  G01N33/66 ,  G01N33/96 ,  G01R35/00

CPC classification number: A61B5/1495 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/6852 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7225 ,  A61B5/7242 ,  A61B5/746 ,  A61M5/14276 ,  A61M5/1582 ,  A61M5/1723 ,  G01N27/026 ,  G01N27/028 ,  G01N27/416 ,  G01N27/4163 ,  G01N33/49 ,  G01N33/66 ,  G01N33/96 ,  G01R35/00 ,  G01R35/005 ,  A61B2562/0214 ,  A61B2562/04 ,  A61M5/14244 ,  A61M2005/1726

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

公开(公告)号：US20240115153A1

公开(公告)日：2024-04-11

申请号：US18527818

申请日：2023-12-04

Applicant: Medtronic MiniMed, Inc.

Inventor： Andrea Varsavsky ,  Fei Yu ,  Michael E. Miller ,  Ning Yang

IPC: A61B5/0537 ,  A61B5/00 ,  A61B5/0538 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61M5/158 ,  G01N27/02

CPC classification number: A61B5/0537 ,  A61B5/0538 ,  A61B5/14532 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/7221 ,  A61B5/7246 ,  A61M5/1582 ,  G01N27/026 ,  A61M2005/1726

Abstract: Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.

公开(公告)号：US11844598B2

公开(公告)日：2023-12-19

申请号：US16391666

申请日：2019-04-23

Applicant: Medtronic MiniMed, Inc.

Inventor： Andrea Varsavsky ,  Fei Yu ,  Michael E. Miller ,  Ning Yang

IPC: A61B5/0537 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/00 ,  A61M5/158 ,  A61B5/0538 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/1486 ,  G01N27/02 ,  A61M5/172 ,  A61M5/142

CPC classification number: A61B5/0537 ,  A61B5/0538 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/7221 ,  A61B5/7246 ,  A61M5/1582 ,  G01N27/026 ,  A61B5/6849 ,  A61M5/14244 ,  A61M5/14276 ,  A61M2005/1726

Abstract: Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.

公开(公告)号：US11717179B2

公开(公告)日：2023-08-08

申请号：US17855865

申请日：2022-07-01

Applicant: Medtronic MiniMed, Inc.

Inventor： Andrea Varsavsky ,  Fei Yu ,  Ning Yang

IPC: A61B5/0537 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/00 ,  A61M5/158 ,  A61B5/0538 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/1486 ,  G01N27/02 ,  A61M5/172 ,  A61M5/142

CPC classification number: A61B5/0537 ,  A61B5/0538 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/7221 ,  A61B5/7246 ,  A61M5/1582 ,  G01N27/026 ,  A61B5/6849 ,  A61M5/14244 ,  A61M5/14276 ,  A61M2005/1726

Abstract: Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.

公开(公告)号：US20220378315A1

公开(公告)日：2022-12-01

申请号：US17855865

申请日：2022-07-01

Applicant: Medtronic MiniMed, Inc.

Inventor： Andrea Varsavsky ,  Fei Yu ,  Ning Yang

IPC: A61B5/0537 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/00 ,  A61M5/158 ,  A61B5/0538 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/1486 ,  G01N27/02

Abstract: Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.

公开(公告)号：US20220133179A1

公开(公告)日：2022-05-05

申请号：US17571723

申请日：2022-01-10

Applicant: Medtronic MiniMed, Inc.

Inventor： Ning Yang ,  Raghavendhar Gautham ,  Bradley C. Liang ,  Rajiv Shah

IPC: A61B5/1495 ,  G01R35/00 ,  A61B5/1486 ,  A61B5/00 ,  A61M5/142 ,  A61M5/158 ,  G01N33/49 ,  A61B5/145 ,  A61B5/1459 ,  A61B5/0538 ,  A61B5/1473 ,  G01N27/02 ,  G01N27/416 ,  G01N33/66 ,  G01N33/96 ,  A61B5/0537 ,  A61M5/172

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

公开(公告)号：US10321865B2

公开(公告)日：2019-06-18

申请号：US15816559

申请日：2017-11-17

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Raghavendhar Gautham ,  Ning Yang ,  Rajiv Shah

IPC: A61B5/00 ,  A61B5/145 ,  G01N27/02 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/053 ,  G01N33/49 ,  G01N33/66 ,  G01N27/416 ,  G01R35/00 ,  A61M5/158 ,  A61M5/142 ,  A61M5/172 ,  G01N33/96

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

公开(公告)号：US10321844B2

公开(公告)日：2019-06-18

申请号：US14466138

申请日：2014-08-22

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Andrea Varsavsky ,  Fei Yu ,  Michael E. Miller ,  Ning Yang

IPC: A61B5/1495 ,  A61B5/053 ,  A61B5/145 ,  A61B5/1468 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/1486 ,  G01N27/02 ,  A61M5/158 ,  A61M5/172 ,  A61M5/142

Abstract: Electrochemical Impedance Spectroscopy (EIS) is used in conjunction with continuous glucose monitors and continuous glucose monitoring (CGM) to enable in-vivo sensor calibration, gross (sensor) failure analysis, and intelligent sensor diagnostics and fault detection. An equivalent circuit model is defined, and circuit elements are used to characterize sensor behavior.