公开(公告)号：US09240505B2

公开(公告)日：2016-01-19

申请号：US13883828

申请日：2011-10-28

申请人： Tadahiro Ohmi ,  Tomotsugu Ohashi ,  Kazuhiro Yoshikawa ,  Tatsuro Yoshida ,  Teppei Uchimura ,  Kazuki Soeda ,  Shigetoshi Sugawa

发明人： Tadahiro Ohmi ,  Tomotsugu Ohashi ,  Kazuhiro Yoshikawa ,  Tatsuro Yoshida ,  Teppei Uchimura ,  Kazuki Soeda ,  Shigetoshi Sugawa

IPC分类号： H01L21/00 ,  H01L21/20 ,  H01L31/0248 ,  H01L21/306 ,  H01L21/67 ,  H01L29/786 ,  H01L27/146

CPC分类号： H01L31/0248 ,  H01L21/30604 ,  H01L21/6708 ,  H01L27/1464 ,  H01L29/78603

摘要： A method of etching capable of rapidly and flatly performing wet etching on a Si substrate using fluonitric acid represented by HF(a)HNO3(b)H2O(c) (where the unit of a, b and c is wt % and a+b+c=100). The etching rate of an SiO2 layer with the highly concentrated fluonitric acid is significantly lowered by the appropriate selection of its composition as compared with the etching rate of the Si substrate, and etch the Si substrate until the SiO2 layer is exposed. In this way, it is possible to rapidly etch the Si substrate and significantly enhance the flatness of the etched surface.

摘要翻译： 使用HF（a）HNO 3（b）H 2 O（c）（其中a，b和c的单位为wt％和a + b）表示的氟酸，在Si衬底上快速且平坦地进行湿蚀刻的方法 + c = 100）。 与Si衬底的蚀刻速率相比，通过适当选择其组成，通过适当选择具有高浓度荧光酮的SiO 2层的蚀刻速率，并且蚀刻Si衬底直至暴露SiO 2层。 以这种方式，可以快速蚀刻Si衬底并显着提高蚀刻表面的平坦度。

公开(公告)号：US08535421B2

公开(公告)日：2013-09-17

申请号：US12901350

申请日：2010-10-08

申请人： Tatsuro Yoshida ,  Paul J. Vernucci

发明人： Tatsuro Yoshida ,  Paul J. Vernucci

IPC分类号： B01D53/22 ,  B01D19/00 ,  A61J1/10 ,  A61J1/14

CPC分类号： C12N5/0641 ,  A01N1/0221 ,  A01N1/0226 ,  A61K35/18 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/0231 ,  A61M1/0272 ,  A61M1/342 ,  A61M2202/0208 ,  A61M2202/0225 ,  B01D19/0031 ,  B01D53/22

摘要： A blood storage system. The system has a collection bag for red blood cells; an oxygen/carbon dioxide depletion device; a storage bag for red blood cells; and tubing connecting the collection bag to the depletion device and the depletion device to the storage bag. The depletion device includes a receptacle of a solid material having an inlet and an outlet adapted to receiving and expelling a flushing gas; a plurality of hollow fibers or gas-permeable films extending within the receptacle from an entrance to an exit thereof. The hollow fibers or gas-permeable films are adapted to receiving and conveying red blood cells.

公开(公告)号：US20120100523A1

公开(公告)日：2012-04-26

申请号：US13115532

申请日：2011-05-25

申请人： William J. Federspiel ,  Brian J. Frankowski ,  Tatsuro Yoshida ,  Paul J. Vernucci

发明人： William J. Federspiel ,  Brian J. Frankowski ,  Tatsuro Yoshida ,  Paul J. Vernucci

IPC分类号： A61M1/34

CPC分类号： C12N5/0641 ,  A01N1/0236 ,  A61M1/0272 ,  A61M2202/0208 ,  A61M2202/0429

摘要： An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.

摘要翻译： 氧耗尽装置。 设备有一个墨盒; 多个中空纤维，其在所述药筒内从入口到出口延伸; 一定量的氧清除剂，其被包装在筒内并与多个中空纤维相邻并在其间。 中空纤维适于接收和输送红细胞。 还有一种氧还原装置和从红细胞中除氧的方法。

公开(公告)号：US08071282B2

公开(公告)日：2011-12-06

申请号：US11128576

申请日：2005-05-13

申请人： Mark W Bitensky ,  Tatsuro Yoshida

发明人： Mark W Bitensky ,  Tatsuro Yoshida

IPC分类号： A01N1/02

CPC分类号： C12N5/0641 ,  A01N1/02 ,  A01N1/0226

摘要： There is provided compositions and methods for the storage of red blood cells. The compositions are additive solutions comprising adenine, dextrose, mannitol, NaH2PO4, and optionally NaCl and/or NH4Cl. Composition are preferably used with oxygen-depletion refrigerated storage of red blood cells and may optionally be employed with nutrient supplements extending the useful shelf life of stored blood.

摘要翻译： 提供了用于储存红细胞的组合物和方法。 组合物是包含腺嘌呤，葡萄糖，甘露醇，NaH 2 PO 4和任选的NaCl和/或NH 4 Cl的添加剂溶液。 组合物优选用于红细胞的耗氧冷藏储存，并且可以任选地与延长储存血液的有用保质期的营养补充剂一起使用。

公开(公告)号：US07517453B2

公开(公告)日：2009-04-14

申请号：US10377178

申请日：2003-03-01

申请人： Mark W Bitensky ,  Tatsuro Yoshida ,  Sergey S Shevkoplyas

发明人： Mark W Bitensky ,  Tatsuro Yoshida ,  Sergey S Shevkoplyas

IPC分类号： G01N35/08 ,  G01N21/00 ,  B01D61/00 ,  G01N35/00

CPC分类号： B01L3/5027 ,  B01L2300/0861 ,  B01L2300/123 ,  G01N11/08 ,  Y10T436/11 ,  Y10T436/119163 ,  Y10T436/2575

摘要： A microvascular network device comprising: a substrate; at least one microchannel; at least one opening to the microchannel for sample entry; at least one opening to the microchannel for sample exit; and an aspirator which causes the sample to traverse the microchannel.

摘要翻译： 一种微血管网络装置，包括：基底; 至少一个微通道; 至少一个通向微通道的开口用于进样; 至少一个开口到微通道用于样品出口; 以及使样品穿过微通道的吸气器。

公开(公告)号：US20050023773A1

公开(公告)日：2005-02-03

申请号：US10751478

申请日：2004-01-06

申请人： Minoru Matsuzawa ,  Tatsuro Yoshida

发明人： Minoru Matsuzawa ,  Tatsuro Yoshida

IPC分类号： H01L21/683 ,  B23B31/12 ,  H01L20060101 ,  H01L21/00 ,  H01L21/027 ,  H01L21/302 ,  H01L21/304 ,  H01L21/306 ,  H01L21/68

CPC分类号： H01L21/6838 ,  H01L21/68728 ,  Y10T279/11 ,  Y10T279/17231 ,  Y10T279/18

摘要： A substrate supporting apparatus for supporting a substrate or wafer in a non-contact state by Bernoulli theorem is disclosed. The substrate supporting apparatus 1 comprises a housing 2, a rotatable chuck 3 which is disposed in the housing 2, which is provided at its central portion with a hollow 12 and which supports a substrate 6, and a cylindrical nozzle member 4 which is disposed in the housing 2, which has a nozzle hole 7 and which can vertically move in the hollow 12. A nozzle hole 7 is formed in a central portion of the nozzle member 4. Gas is discharged from a gas source 8 through the nozzle hole 7, thereby holding the substrate 6 by an upper surface of the chuck 3 in a non-contact state. When the substrate 6 is to be detached, the nozzle member 4 is moved upward while discharging gas from the nozzle hole 7, thereby floating the substrate 6.

摘要翻译： 公开了一种用于通过伯努利定理支持处于非接触状态的衬底或晶片的衬底支撑装置。 基板支撑装置1包括壳体2，设置在壳体2中的可旋转卡盘3，其在其中心部分设置有中空部12并支撑基板6，以及圆柱形喷嘴部件4，其设置在 壳体2具有喷嘴孔7并且可以在中空部12中垂直移动。喷嘴孔7形成在喷嘴构件4的中心部分。气体通过喷嘴孔7从气体源8排出， 从而以非接触状态将卡盘3的上表面保持基板6。 当要拆下基板6时，喷嘴构件4在从喷嘴孔7排出气体的同时向上移动，从而使基板6浮起。

公开(公告)号：US4670490A

公开(公告)日：1987-06-02

申请号：US591332

申请日：1984-03-19

申请人： Tatsuro Yoshida ,  Hidematsu Shimasaki ,  Takahisa Minamizono ,  Katsura Ochi

发明人： Tatsuro Yoshida ,  Hidematsu Shimasaki ,  Takahisa Minamizono ,  Katsura Ochi

IPC分类号： C08L27/00 ,  B42D15/00 ,  C08K5/10 ,  C08L1/00 ,  C08L7/00 ,  C08L21/00 ,  C08L27/06 ,  C08L33/00 ,  C08L33/02 ,  C08L33/04 ,  C08L33/06 ,  C08L67/00 ,  C08L67/02 ,  C08K5/49

CPC分类号： C08L27/06 ,  C08L33/06 ,  C08L67/02 ,  Y10T428/28

摘要： A vinyl chloride resin composition with a yield stress of 1 to 5 g/mm.sup.2, composed of(A) 100 parts by weight of a vinyl chloride resin containing 0 to about 20% by weight of a comonomer,(B) about 10 to about 80 parts by weight, per 100 parts by weight of the resin (A), of (B-1) a liquid polyester plasticizer having a number average molecular weight (Mn) of not less than about 1,500 and 0 to about 10 parts by weight, per 100 parts by weight of the resin (A), of (B-2) a plasticizer for the resin (A), which is other than said plasticizer (B-1), and(C) about 0.2 to about 200% by weight, based on the total weight of said plasticizers (B-1) and (B-2), of a low-molecular-weight acrylic or methacrylic resin having a number average molecular weight (Mn) of about 1,500 to about 50,000 and being solid at 23.degree. C.

摘要翻译： 屈服应力为1〜5g / mm 2的氯乙烯树脂组合物由（A）100重量份含有0〜20重量％共聚单体的氯乙烯树脂（B）约10〜约 80重量份，相对于100重量份树脂（A），（B-1）数均分子量（＆amp;上＆amp;＆gt; Mn）不低于约1,500的液体聚酯增塑剂和0至约10重量份 （B-2）树脂（A）的增塑剂（B-1）以外的树脂（A）100重量份，（C）约0.2〜约200重量份 基于所述增塑剂（B-1）和（B-2）的总重量，重量百分比为数均分子量（＆amp;＆gt;＆amp; Mn）为约1,500至约 50,000，在23℃固体。

公开(公告)号：US08828226B2

公开(公告)日：2014-09-09

申请号：US12386108

申请日：2009-04-14

申请人： Sergey Shevkoplyas ,  Tatsuro Yoshida ,  Mark Bitensky

发明人： Sergey Shevkoplyas ,  Tatsuro Yoshida ,  Mark Bitensky

IPC分类号： B01D63/00 ,  G01N33/48 ,  B01D63/08 ,  B01L3/00 ,  G01N33/80 ,  G01N11/08

CPC分类号： B01D63/088 ,  B01L3/5027 ,  B01L2200/0647 ,  B01L2300/0861 ,  B01L2300/123 ,  B01L2400/0439 ,  G01N11/08 ,  G01N33/80 ,  Y10S707/99945 ,  Y10S707/99948

摘要： A system for assessing the microvascular fitness of a sample of stored red blood cells. The system has a network device having at least one network unit. The network unit has a single inlet and a single outlet for the sample and a plurality of microchannels. The plurality of microchannels receive the sample from the single inlet and drain the sample into the single outlet. The network unit includes an aspiration pressure means for providing movement of liquid sample through the at least one network unit. The system further includes an analysis unit that receives the network device therein. The analysis unit includes a sensor for capturing measurements related to the sample and a processor capable of comparing the captured measurements to measurements stored in a database of healthy red blood cells to determine the microvascular fitness of the stored red blood cells.

摘要翻译： 用于评估储存的红细胞样品的微血管适应度的系统。 该系统具有至少一个网络单元的网络设备。 网络单元具有用于样品的单个入口和单个出口以及多个微通道。 多个微通道从单个入口接收样品并将样品排入单个出口。 网络单元包括用于提供液体样品通过至少一个网络单元的运动的抽吸压力装置。 该系统还包括在其中接收网络设备的分析单元。 分析单元包括用于捕获与样本相关的测量的传感器和能够将所捕获的测量与存储在健康红细胞数据库中的测量进行比较的处理器，以确定所存储的红细胞的微血管适应度。

公开(公告)号：US20120077182A1

公开(公告)日：2012-03-29

申请号：US13310289

申请日：2011-12-02

申请人： MARK W. BITENSKY ,  Tatsuro Yoshida

发明人： MARK W. BITENSKY ,  Tatsuro Yoshida

IPC分类号： C12N5/078

CPC分类号： C12N5/0641 ,  A01N1/02 ,  A01N1/0226

摘要： A method for the storage of red blood cells provides for mixing an additive solution with packed red blood cells to create a suspension of red blood cells. The method further provides for reducing the oxygen in the suspension of red blood cells; and storing the suspension of red blood cells under oxygen-depleted storage.

摘要翻译： 用于储存红细胞的方法提供将添加剂溶液与填充的红细胞混合以产生红细胞的悬浮液。 该方法进一步提供了减少红细胞悬浮液中的氧气; 并将红细胞的悬浮液储存在耗尽氧的存储下。

公开(公告)号：US07723017B2

公开(公告)日：2010-05-25

申请号：US11138135

申请日：2005-05-26

申请人： Mark W Bitensky ,  Tatsuro Yoshida

发明人： Mark W Bitensky ,  Tatsuro Yoshida

IPC分类号： A01N1/02

CPC分类号： A01N1/0226 ,  A01N1/02

摘要： There are provided methods and compositions for the storage of red blood cells. The compositions are metabolic supplements that are preferably added to refrigerated red blood cells suspended in an additive solution. Red blood cells are preferably stored under conditions of oxygen-depletion. Metabolic compositions comprises pyruvate, inosine, adenine, and optionally dibasic sodium phosphate and/or monobasic sodium phosphate.

摘要翻译： 提供了用于储存红细胞的方法和组合物。 组合物是代谢补充剂，其优选加入到悬浮在添加剂溶液中的冷冻红细胞中。 红细胞优选在氧耗尽的条件下储存。 代谢组合物包括丙酮酸，肌苷，腺嘌呤和任选的磷酸氢二钠和/或磷酸二氢钠。