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    METHOD OF ELECTRICALLY DETECTING A NUCLEIC ACID MOLECULE
    21.
    发明申请
    METHOD OF ELECTRICALLY DETECTING A NUCLEIC ACID MOLECULE 审中-公开
    电流检测核酸分子的方法

    公开(公告)号：US20100285601A1

    公开(公告)日：2010-11-11

    申请号：US12680290

    申请日：2007-09-28

    申请人： Jinming Kong ,  Yi Fan ,  Xiantong Chen

    发明人： Jinming Kong ,  Yi Fan ,  Xiantong Chen

    IPC分类号： G01N27/00

    CPC分类号： G01N33/54306 ,  Y10T436/143333

    摘要： The method is performed by means of a pair of electrodes that are arranged at a distance and within a sensing zone. A nucleic acid capture molecule with an uncharged backbone and a nucleotide sequence that is at least partially complementary to at least a portion of a strand of the target nucleic acid molecule, is immobilised on an immobilisation unit. The immobilisation unit, which is arranged within the sensing zone, is contacted with a solution suspected to comprise the target nucleic acid molecule, which hybridizes to the nucleic acid capture molecule. An activation agent is added, which has an electrostatic net charge complementary to the net charge of the target nucleic acid molecule. It associates to the complex of nucleic acid capture molecule and target nucleic acid molecule. Added is a water soluble polymer with at least one polymer strand and with an electrostatic net charge that is complementary to the net charge of the activation agent. Thus the polymer associates to the activation agent. A metal salt is added, which can act as an oxidant and the metal ions of which have an electrostatic net charge complementary to the net charge of the polymer. The metal ions associate to the polymer. Upon adding a reducing agent, the latter reduces the metal ions, forming a metal wire. The presence of the analyte molecule is determined based on an electrical characteristic of a region in the sensing zone that is affected by the metal wire.

    摘要翻译： 该方法通过一对电极进行，该对电极被布置在距离和感测区域内。 具有不带电荷的骨架的核酸捕获分子和与靶核酸分子的链的至少一部分至少部分互补的核苷酸序列被固定在固定化单元上。 布置在感测区内的固定单元与疑似包含与核酸捕获分子杂交的靶核酸分子的溶液接触。 加入活化剂，其具有与靶核酸分子的净电荷互补的静电净电荷。 它与核酸捕获分子和靶核酸分子的复合物结合。 添加的是具有至少一个聚合物链和具有与活化剂的净电荷互补的静电净电荷的水溶性聚合物。 因此，聚合物与活化剂结合。 加入金属盐，其可以用作氧化剂，并且其金属离子具有与聚合物的净电荷互补的静电净电荷。 金属离子与聚合物缔合。 加入还原剂后，还原金属离子，形成金属丝。 分析物分子的存在基于受金属线影响的感测区域中的区域的电特性来确定。

    Digital Display System With Media Processor And Wireless Audio
    25.
    发明申请
    Digital Display System With Media Processor And Wireless Audio 有权
    具有媒体处理器和无线音频的数字显示系统

    公开(公告)号：US20080301335A1

    公开(公告)日：2008-12-04

    申请号：US12129625

    申请日：2008-05-29

    申请人： Bing Yeh ,  Christopher Deng ,  Yi Fan ,  Igor El Gorriaga

    发明人： Bing Yeh ,  Christopher Deng ,  Yi Fan ,  Igor El Gorriaga

    IPC分类号： G06F13/00 ,  G06F3/00 ,  G06F13/42

    CPC分类号： H04N1/00281 ,  H04N1/00283 ,  H04N1/00315 ,  H04N2201/0087 ,  H04N2201/0089

    摘要： The present invention relates to a media processing system that comprises a bus for communicating digital signals thereon with a media processor connected to the bus, for processing signals supplied thereon. The system further has a display device connected to the bus for displaying digitized images thereon, received from the bus. The system has an audio transmitter connected to the bus, for wirelessly transmitting audio digital signals from the bus. The system further has a connectable memory for connecting to the bus and for supplying signals representing digitized images and audio digital signals to the bus. Finally the system has a receiver to receive encoded digitized images or audio digital signals for supplying the received signals to the bus for storage in the memory.

    摘要翻译： 媒体处理系统本发明涉及一种媒体处理系统，它包括一个用于在其上传送数字信号的总线与连接到总线的媒体处理器，用于处理在其上提供的信号。 该系统还具有连接到总线的显示装置，用于从总线接收数字化图像。 该系统具有连接到总线的音频发射器，用于从总线无线传输音频数字信号。 该系统还具有用于连接到总线的可连接存储器，并用于向总线提供表示数字化图像和音频数字信号的信号。 最后，该系统具有接收编码的数字化图像或音频数字信号的接收器，用于将接收的信号提供给总线以存储在存储器中。