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公开(公告)号:US20080156063A1
公开(公告)日:2008-07-03
申请号:US11983369
申请日:2007-11-07
申请人: Ling Hou , Guang-Hui Xie , Jing Yang , Yong-Guang Wang , Ling Yi
发明人: Ling Hou , Guang-Hui Xie , Jing Yang , Yong-Guang Wang , Ling Yi
CPC分类号: B21K23/00
摘要: An exemplary metallic frame (60) is formed by forging and precise machining of a workpiece. The forging process is performed before the precise machining process, a hardness of the frame is larger than that of the workpiece and a surface roughness Ra of the frame reaches about 6.4 microns. The present invention further provides a method of making the frame. The method includes as follows: feeding workpiece process (12) for providing a workpiece (20); forging process (14), the workpiece be forged to form a preform (40); and precise machining process (18), the preform be precisely machined to form a frame.
摘要翻译: 通过对工件进行锻造和精密加工来形成示例性的金属框架(60)。 锻造过程在精密加工过程之前执行,框架的硬度大于工件的硬度,并且框架的表面粗糙度Ra达到约6.4微米。 本发明还提供一种制作框架的方法。 该方法包括:进给用于提供工件(20)的工件加工(12); 锻造工艺(14),锻造工件以形成预制件(40); 和精密加工工艺(18),预制件被精加工以形成框架。
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22.
公开(公告)号:US20080085050A1
公开(公告)日:2008-04-10
申请号:US11856208
申请日:2007-09-17
申请人: Adrian Barbu , Yefeng Zheng , Jing Yang , Bogdan Georgescu , Dorin Comaniciu
发明人: Adrian Barbu , Yefeng Zheng , Jing Yang , Bogdan Georgescu , Dorin Comaniciu
IPC分类号: G06K9/00
CPC分类号: G06K9/6292
摘要: A system and method for detecting an object in a high dimensional image space is disclosed. A three dimensional image of an object is received. A first classifier is trained in the marginal space of the object center location which generates a predetermined number of candidate object center locations. A second classifier is trained to identify potential object center locations and orientations from the predetermined number of candidate object center locations and maintaining a subset of the candidate object center locations. A third classifier is trained to identify potential locations, orientations and scale of the object center from the subset of the candidate object center locations. A single candidate object pose for the object is identified.
摘要翻译: 公开了一种用于检测高维图像空间中的对象的系统和方法。 接收对象的三维图像。 在对象中心位置的边缘空间中训练第一分类器,其生成预定数量的候选对象中心位置。 训练第二分类器以从预定数量的候选对象中心位置识别潜在对象中心位置和方向,并维护候选对象中心位置的子集。 训练第三分类器以从候选对象中心位置的子集中识别对象中心的潜在位置,方向和尺度。 识别对象的单个候选对象姿势。
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公开(公告)号:US20050234030A1
公开(公告)日:2005-10-20
申请号:US11028896
申请日:2005-01-03
申请人: Wilmin Bartolini , Brian Cali , Barbara Chen , Yueh-Tyng Chien , Mark Currie , G. Milne , James Pearson , John Talley , Jing Yang , Craig Zimmerman
发明人: Wilmin Bartolini , Brian Cali , Barbara Chen , Yueh-Tyng Chien , Mark Currie , G. Milne , James Pearson , John Talley , Jing Yang , Craig Zimmerman
IPC分类号: A61K31/496 , A61K31/497 , A61K31/501 , A61K31/53 , A61K31/5377 , A61K31/541 , C07D209/18 , C07D209/26 , C07D209/28 , C07D401/06 , C07D405/06 , C07D409/06 , C07D413/02 , C07D417/02 , C07D43/02
CPC分类号: C07D209/18 , C07D209/26 , C07D209/28 , C07D401/06 , C07D405/06 , C07D409/06
摘要: Certain substituted indoles that are modulators of one or more or of CRTH2, COX-2 AND FAAH are described. The compounds are useful for treatment of pain and/or inflammation as well as other disorders.
摘要翻译: 描述了作为一种或多种或CRTH2,COX-2和FAAH的调节剂的某些取代的吲哚。 该化合物可用于治疗疼痛和/或炎症以及其它疾病。
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公开(公告)号:US20050208542A1
公开(公告)日:2005-09-22
申请号:US11031531
申请日:2005-01-07
申请人: James Rusling , John Schenkman , Liping Zhou , Jing Yang
发明人: James Rusling , John Schenkman , Liping Zhou , Jing Yang
IPC分类号: C12M1/34 , C12Q1/68 , G01N33/53 , G01N33/543
CPC分类号: C12Q1/6825 , G01N33/5308 , G01N33/5438
摘要: A biosensor is described comprising an electrode, a protein layer (s), and a double-stranded polynucleotide layer (s). Also included do arrays, kits, and instruments comprise the biosensors. The biosensors may be used to detect double-stranded polynucleotide damage resulting from metabolism of a test compound, such as a drug candidate, by the protein in the protein layer.
摘要翻译: 描述了包括电极,蛋白质层和双链多核苷酸层的生物传感器。 阵列,套件和仪器也包括生物传感器。 生物传感器可以用于检测由蛋白质层中的蛋白质测试化合物(例如候选药物)的代谢产生的双链多核苷酸损伤。
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公开(公告)号:US09963675B2
公开(公告)日:2018-05-08
申请号:US15144628
申请日:2016-05-02
申请人: Henry Klassen , Jing Yang
发明人: Henry Klassen , Jing Yang
IPC分类号: C12N5/079 , A61K35/30 , A61K9/00 , C12N5/0797
CPC分类号: C12N5/0621 , A61K9/0019 , A61K9/0048 , A61K35/30 , C12N5/0623 , C12N2500/02 , C12N2500/38 , C12N2500/90 , C12N2509/00 , C12N2533/52
摘要: Disclosed herein are compositions and methods for treating, ameliorating or preventing a retinal disease or condition; improving a photopic (day light) vision; for improving correcting visual acuity, improving macular function, improving a visual field, or improving scotopic (night) vision by administration of retinal progenitor cells. The subject matter described herein also provides cell populations comprising retinal progenitor cells and methods of isolation thereof.
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公开(公告)号:US09107897B2
公开(公告)日:2015-08-18
申请号:US14118223
申请日:2012-05-17
申请人: Henry Klassen , Jing Yang
发明人: Henry Klassen , Jing Yang
IPC分类号: A61K35/30 , A61K9/00 , C12N5/0797
CPC分类号: C12N5/0621 , A61K9/0019 , A61K9/0048 , A61K35/30 , C12N5/0623 , C12N2500/02 , C12N2500/38 , C12N2500/90 , C12N2509/00 , C12N2533/52
摘要: Disclosed herein are compositions and methods for treating, ameliorating or preventing a retinal disease or condition; improving a photopic (day light) vision; for improving correcting visual acuity, improving macular function, improving a visual field, or improving scotopic (night) vision by administration of retinal progenitor cells. The subject matter described herein also provides cell populations comprising retinal progenitor cells and methods of isolation thereof.
摘要翻译: 本文公开了治疗,改善或预防视网膜疾病或病症的组合物和方法; 改善视力(日光); 用于通过施用视网膜祖细胞来改善矫正视力,改善黄斑功能,改善视野或改善暗视(夜间)视力。 本文所述的主题还提供了包含视网膜祖细胞的细胞群及其分离方法。
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公开(公告)号:US20140070239A1
公开(公告)日:2014-03-13
申请号:US13995122
申请日:2012-11-07
申请人: Jing Yang , Jianshe Xue , Xiang Liu
发明人: Jing Yang , Jianshe Xue , Xiang Liu
IPC分类号: H01L33/08
CPC分类号: H01L33/08 , G02F1/1362 , H01L27/1288
摘要: An array substrate and a method for fabricating the same are disclosed. The method for fabricating the array substrate comprises: forming a pattern of a gate electrode (2) and a common electrode (3) on a substrate (1); forming a pattern of a gate insulating layer (4), an active layer (5), a source/drain electrode layer (6) and a first passivation layer (7), wherein the first passivation layer (7) has a via hole and a thin film transistor (TFT) channel window, and the TFT channel window is located above the gate electrode (2); forming a TFT channel and a pixel electrode (9) with slits, wherein the pixel electrode (9) is connected to one of the source/drain electrode (6) through the via hole. The method is not only simple and stable but also improves the TFT quality.
摘要翻译: 公开了阵列基板及其制造方法。 制造阵列基板的方法包括:在基板(1)上形成栅极(2)和公共电极(3)的图案; 形成栅极绝缘层(4),有源层(5),源/漏电极层(6)和第一钝化层(7)的图案,其中第一钝化层(7)具有通孔和 薄膜晶体管(TFT)沟道窗口,TFT沟道窗口位于栅电极(2)的上方; 形成具有狭缝的TFT沟道和像素电极(9),其中,所述像素电极(9)通过所述通孔与所述源极/漏极电极(6)中的一个连接。 该方法不仅简单稳定,而且提高了TFT的质量。
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公开(公告)号:US20100260827A1
公开(公告)日:2010-10-14
申请号:US11646706
申请日:2006-12-28
申请人: Sendurai Mani , Jing Yang , Robert A. Weinberg
发明人: Sendurai Mani , Jing Yang , Robert A. Weinberg
IPC分类号: A61K9/127 , A61K39/395 , A61K38/43 , C12Q1/68 , C12Q1/02 , A61P35/04 , A61K31/7088 , A61K38/00
CPC分类号: G01N33/57492 , C12N2799/027 , C12N2799/06 , G01N33/5011
摘要: The invention relates to methods and compositions for inhibiting metastasis, such as by inhibiting FOXC2 expression or activity. The invention further relates to methods of prognosticating, diagnosing, and assisting in the diagnosis of metastasis in an individual, or of determining the metastatic potential of a tumor. The invention further relates to methods of identifying agents which inhibit metastasis.
摘要翻译: 本发明涉及抑制转移的方法和组合物,例如通过抑制FOXC2表达或活性。 本发明还涉及预测,诊断和辅助个体中转移的诊断或确定肿瘤的转移潜力的方法。 本发明还涉及鉴定抑制转移的药物的方法。
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29.
公开(公告)号:US20100086955A1
公开(公告)日:2010-04-08
申请号:US12571538
申请日:2009-10-01
IPC分类号: C12Q1/48 , C07C69/76 , C07D291/00 , C07D239/02 , C07D235/12
CPC分类号: C07D233/60 , A61K9/146 , A61K31/4166 , A61K31/4172 , A61K31/54 , C07D207/273 , C07D235/16 , C07D239/26 , C07D263/14 , C07D263/32 , C07D291/06 , G01N2333/91188
摘要: Ghrelin O-acyltransferase (GOAT) is inhibited with designed small molecules. Methods comprise contacting the GOAT with an inhibitor and detecting a resultant inhibition.
摘要翻译: 生长素释放肽O-酰基转移酶(GOAT)被设计的小分子抑制。 方法包括使GOAT与抑制剂接触并检测所得抑制。
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30.
公开(公告)号:US20090170141A1
公开(公告)日:2009-07-02
申请号:US11967171
申请日:2007-12-29
CPC分类号: C12Q1/48 , G01N2333/91051
摘要: Ghrelin is acylated ghrelin O-acyltransferase. Ghrelin O-acyltransferase assays comprise contacting a mixture of ghrelin and recombinant ghrelin O-acyltransferase with an agent; and detecting a resultant decrease in acylation of the ghrelin by the acyltransferase.
摘要翻译: 生长素释放肽是酰化的生长素释放肽O-酰基转移酶。 生长素释放肽O-酰基转移酶测定包括将生长素释放肽和重组生长素释放肽O-酰基转移酶的混合物与试剂接触; 并通过酰基转移酶检测产生的生长素释放肽酰化的降低。
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