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21.发明申请公开(公告)号：US20070005169A1
公开(公告)日：2007-01-04
申请号：US10573448
申请日：2004-09-24
申请人： Peter Röhnert , Frank Striggow
发明人： Peter Röhnert , Frank Striggow
IPC分类号： G06F19/00
CPC分类号： G01N35/028 , G01N1/31 , G01N35/0099 , G01N2035/00326 , G01N2035/0422 , G01N2035/0467
摘要： The present invention relates to a device for automatically carrying out laboratory operations on cell or tissue samples, which comprises a plurality of modular stations, each of which carries out at least one operation in a total sequence of operations, and at least one support unit for transporting sample containers to and between the stations, the device having at least one station for automatically changing liquid media in the sample containers.
摘要翻译： 本发明涉及一种用于自动执行细胞或组织样本的实验室操作的装置，其包括多个模块化站，每个模块站在整个操作序列中执行至少一个操作，以及至少一个支撑单元，用于 将样品容器运送到工位之间和之间，该装置具有至少一个用于在样品容器中自动改变液体介质的工位。
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公开(公告)号：US07105132B2
公开(公告)日：2006-09-12
申请号：US10082974
申请日：2002-02-25
IPC分类号： B01L3/02
CPC分类号： B01L9/52 , B01J19/00 , B01J19/0046 , B01J2219/00011 , B01J2219/00315 , B01J2219/00328 , B01J2219/00691 , B01J2219/00695 , B01J2219/007 , B01J2219/00702 , B01J2219/00707 , B01L9/523 , B01L2300/0829 , B01L2300/0893 , C40B60/14 , G01N35/0099 , G01N35/028 , G01N35/1002 , G01N35/1074 , G01N2035/00326 , G01N2035/042 , G01N2035/0422 , G01N2035/0425 , Y10T436/11 , Y10T436/110833 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/25 , Y10T436/2575
摘要： A chemical solution distribution system and method that includes or employs a plurality of liquid handlers where each of the liquid handlers includes a movable table that engages a sample multiwell plate and can align pipettes of the station with different subsets of wells of the multiwell plate where the number of wells of the multiwell plate is a multiple of the number of pipettes of the head of the pipette station. The system further includes and employs four different pumps to enable the system and method to supply four different solutions to wash stations of each of the four liquid handlers.
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公开(公告)号：US06979425B1
公开(公告)日：2005-12-27
申请号：US09699818
申请日：2000-10-30
CPC分类号： B01J19/0046 , B01J2219/00364 , B01J2219/00387 , B01J2219/00531 , B01J2219/00659 , B01J2219/00691 , B01J2219/00693 , B01J2219/00722 , B01L3/0244 , G01N2035/00158 , G01N2035/0422 , Y10T436/112499 , Y10T436/114998 , Y10T436/2575
摘要： A high capacity microarrayer for spotting solution onto slides in an automated microarray dispensing device. A microplate indexing device automatically moves, in sequence, a plurality of microplates to a solution removal area. A dispense head accesses each microplate at the solution removal area to remove solution from the microplate. The dispense head then moves to a slide positioning station to spot slides at the slide positioning station. In a preferred embodiment of the present invention, the microplate indexing station has at least one input stacking chamber for stacking microplates, and at least one output stacking chamber for stacking microplates. A walking beam indexer is disposed between the at least one input stacking chamber and the at least one output stacking chamber. The walking beam indexer is for moving microplates from said at least one input stacking chamber to said at least one output stacking chamber. While at the solution removal area, a lid lifter lifts the lid off each microplate to permit the microplate to be accessed by the dispense head for solution removal. After the solution is removed, the lid lifter replaces the lid. In another preferred embodiment, there is at least one light source capable of illuminating the slides, and at least one camera operating in conjunction with the at least one light source. The at least one camera is capable of acquiring and transmitting slide image data to a computer. The computer is programmed to receive the slide image and analyze it. The computer will then generate post analysis data based on the analysis of the slide image data. The post analysis data is available for improving the spotting of the solution onto the slides. In a preferred embodiment, the slide image data includes information relating to slide alignment, information relating to spot quality, and slide identification information. In a preferred embodiment, the analysis of the information relating to slide alignment enables the computer to make automatic adjustments to the relative positions of the at least one dispense head and the slides to increase the accuracy of the spotting. In a preferred embodiment, the analysis of the information relating to spot quality identifies a spot as pass or fail. An operator is then able to rework the spot. In a preferred embodiment, the analysis of the slide identification information enables the computer to track each slide.
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24.发明申请Device for dispensing and observing the luminescence of individual specimens in multi-specimen arrangements 失效用于分配和观察多标本布置中各个样本的发光的装置公开(公告)号：US20040022689A1
公开(公告)日：2004-02-05
申请号：US10630199
申请日：2003-07-30
申请人： CyBio AG
发明人： Juergen Wulf , Werner Pongratz , Andreas Fina , Michael Heil , Michael Jurtz
IPC分类号： G01N021/00
CPC分类号： G01N35/109 , G01N21/6428 , G01N21/6452 , G01N35/1011 , G01N35/1065 , G01N2021/6443 , G01N2021/6482 , G01N2035/0422
摘要： The invention is directed to a device for dispensing and observing the luminescence of individual specimens in multi-specimen arrangements, particularly for the examination of biological, chemical or cytobiological assays with high specimen throughput. It is the object of the invention to find a novel possibility for dispensing in multi-specimen arrangements (microplates) and for observing the luminescence of the individual specimens, particularly for examining biological assays with high specimen throughput, which permits an immediate observation of the course of luminescence while dispensing proceeds at the same time without being limited to a determined type of microplate. This object is met, according to the invention, in that the dispensing unit has at least one linear dispensing comb containing an even number of dispensing nozzles representing an integral divisor of the number of wells along one dimension of the microplate, the dispensing combs are arranged so as to be displaceable orthogonal to their longitudinal dimension, every dispensing comb is connected to a controllable pump for metering the amount of liquid to be dispensed without immersion in the wells of the microplate, and the CCD camera is oriented by a fast optical system to a large-area rectangular region of the underside of the microplate across from the dispensing unit, the surface being adapted to the dimension of the dispensing comb and to the area of the microplate covered by the dispensing comb, so that the elapsed time for the luminescence is measurable simultaneously while dispensing continues.
摘要翻译： 本发明涉及一种用于分配和观察多个样品装置中的各个样品的发光的装置，特别是用于以高样品生产量检查生物，化学或细胞生物学测定。 本发明的目的是找到一种新型的多样品布置（微孔板）分配和用于观察单个样品的发光的可能性，特别是用于检查具有高样品通量的生物测定法，其允许立即观察该过程 的发光，同时分配在同一时间进行，而不限于确定类型的微孔板。 根据本发明，符合本发明的目的在于，分配单元具有至少一个线性分配梳，其包含偶数个分配喷嘴，分配喷嘴表示沿着微孔板的一个维度的孔数的积分因子，分配梳被布置 为了能够与其纵向尺寸正交地移动，每个分配梳都连接到可控制的泵，用于计量待分配的液体量而不浸没在微板的孔中，并且CCD相机通过快速光学系统定向 微孔板下面的从分配单元的大面积矩形区域，该表面适于分配梳的尺寸和由分配梳覆盖的微板的面积，使得发光的经过时间 可同时测量，同时分配持续。
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公开(公告)号：US5055408A
公开(公告)日：1991-10-08
申请号：US590530
申请日：1990-09-28
申请人： Yuji Higo , Hidechika Hayashi , Shuji Iwasaki
发明人： Yuji Higo , Hidechika Hayashi , Shuji Iwasaki
CPC分类号： G01N35/026 , G01N35/0098 , G01N2035/00386 , G01N2035/00534 , G01N2035/041 , G01N2035/0422 , G01N2035/0425 , G01N35/028 , G01N35/1079 , G01N35/1083 , Y10S436/809 , Y10T436/114165 , Y10T436/114998
摘要： An automated immunoassay analyzser comprising a transfer route on which test plates each having a plurality of chambers for immunological reaction opened upwards are transferred continually with a constant interval of time, and devices of at least A, B, C and D described below which are arranged on the transfer route from upstream to downstream in the order referred to in which the device A is for injecting the sample comprising a vertically and horizonally driven support, a pipet fixed to the support, and a nozzle tip usable for a single sample and removably attached to the lower end of the pipet, the device B is for B/F separation and the device C is for injecting the substrate solution and both devices are integratedly combined and comprise a vertically and horizontally driven support, a washing tube supported by the support, a temperature controllable solution reservoir block fixed to the support, a substrate injection tube provided to the lower side of the reservoir block, the washing tube and the substrate solution injection tube being arranged in alignment and spaced each other according to the pitch of the cup arrangement, and the device D is for photometry with which to measure optically detectable changes caused in the substrate in the chamber of immunological reaction.
摘要翻译： 一种自动化免疫测定分析装置，其特征在于，具有转印路径，在所述转印路径上，将具有多个向上方开放的免疫反应室的试验板以恒定的时间间隔连续地传送，并且将下述的至少A，B，C，D的装置配置 在从上游到下游的传输路线上，其中装置A用于注射包括垂直和水平驱动的支撑件的样品，固定到支撑件的移液管和可用于单个样品的喷嘴末端，并且可拆卸地附接 在移液器的下端，装置B用于B / F分离，并且装置C用于注入基质溶液，并且两个装置被整体组合并且包括垂直和水平驱动的支撑件，由支撑件支撑的洗涤管， 固定在支撑体上的温度可控的溶液储存器块，设置在储存器块的下侧的基底注入管 铰链管和衬底溶液注入管根据杯装置的间距排列成对准并彼此隔开，并且装置D用于测光，以测量在免疫反应室中的基底中引起的光学上可检测的变化。
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公开(公告)号：US4259290A
公开(公告)日：1981-03-31
申请号：US49161
申请日：1979-06-18
申请人： Osmo A. Suovaniemi , Pertti Ekholm , Esko Kaukanen
发明人： Osmo A. Suovaniemi , Pertti Ekholm , Esko Kaukanen
CPC分类号： G01N35/04 , G01N2035/0422 , G01N2035/0425 , G01N2035/0491
摘要： The subject of the present invention is a transfer device for analysis equipment, which transfer device comprises a track consisting of, inter alia, guide and support rails on which to transfer a pit plate on a transport cassette along the track. The transport cassette includes a traction rail parallel to the guide and support rails. Traction units are fitted onto the track in the transfer device as means operative jointly with said traction rail to move the transport cassette. In order to control the operation of the traction units, the traction rail is provided with sign codes readable by means of an optical reading device. This indicates the position of the cassette relative to the optical reading device so that the transport cassette may be stopped to position the desired line of pits, transverse to the track for operations to be performed in the analysis equipment, such as liquid dosage, photometric measurement operations, etc.
摘要翻译： 本发明的主题是用于分析设备的转移装置，该转移装置包括由导轨和支撑轨道组成的轨道，在该轨道上沿轨道将输送带上的凹坑板传送到运输盒上。 运输盒包括平行于引导件和支撑轨道的牵引轨道。 牵引单元安装在传送装置的轨道上，作为与所述牵引轨道共同操作的装置以移动运送盒。 为了控制牵引单元的操作，牵引轨具有通过光学读取装置可读的符号代码。 这指示盒相对于光学读取装置的位置，使得运输盒可以停止以定位所需的凹坑线，横向于轨道，用于在分析设备中进行的操作，例如液体剂量，光度测量 作业等
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公开(公告)号：US11864534B2
公开(公告)日：2024-01-09
申请号：US16763239
申请日：2017-11-14
申请人： SELEGGT GmbH
发明人： Tjitze Meter
CPC分类号： A01K43/00 , B65G47/94 , B65G49/05 , G01N5/04 , G01N2035/0422
摘要： The present invention relates to an egg carrier for holding an egg in an egg handling system, wherein the egg carrier comprises;
an egg accommodation,
an egg clamping system to secure an egg in the egg accommodation space, wherein the egg clamping system is moveable between an egg securing position and an egg release position,
an operating system coupled with the egg clamping system to move the clamping system between the egg securing position and the egg release position, wherein the operating system comprises an operating member that is operable externally from the egg carrier.-
公开(公告)号：US20180127220A1
公开(公告)日：2018-05-10
申请号：US15437041
申请日：2017-02-20
申请人： KUO-LUNG LOR
发明人： KUO-LUNG LOR
IPC分类号： B65G65/00
CPC分类号： B65G65/00 , G01N1/36 , G01N35/04 , G01N2035/042 , G01N2035/0422 , G01N2035/0425 , G01N2035/0441
摘要： A transportation system for paraffin embedded tissues includes a placing assembly, a bearing unit and a storage device. The placing assembly includes a horizontal moving assembly, a vertical moving assembly, a rotation assembly and a placing unit. The horizontal and vertical moving assemblies move the placing unit in horizontal and vertical directions, respectively, and the rotation assembly allows the placing unit to rotate around a vertical axis. The bearing unit receives the paraffin embedded tissues. The storage device has a rotation plate including a plurality of receiving slots each for storing the bearing unit. The placing unit is configured to remove the bearing unit from the storage device, move the bearing unit to a processing apparatus located at another side of the placing assembly, remove the bearing unit from the processing apparatus, and transport the bearing unit to the receiving slot of the storage device.
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公开(公告)号：US20180024070A1
公开(公告)日：2018-01-25
申请号：US15547910
申请日：2015-04-30
申请人： Hitachi, Ltd.
发明人： Masahiro OKANOJO , Hideyuki NODA
CPC分类号： G01N21/76 , C12Q1/02 , G01N21/763 , G01N35/00871 , G01N35/025 , G01N35/04 , G01N35/1004 , G01N35/1009 , G01N2035/00277 , G01N2035/00306 , G01N2035/00356 , G01N2035/0422 , G01N2035/0432 , G01N2035/0444 , G01N2201/0231 , G01N2201/064
摘要： A luminometer apparatus includes, inside a light-shielded room, a container rack loaded with holding containers, a dispensation mechanism that dispenses a liquid, a rotary plate that turns, while holding a plurality of reaction containers which accommodate a mixture liquid of a sample and a luminescent reagent on a concentric annular plate, and is provided with a gap allowing the container rack to pass therethrough between at least a pair of adjacent ones of the reaction containers, and a photodetection unit that performs luminescence measurements. The light-shielded room has an insertion opening having a width allowing for insertion of the container rack and provided to be openable and closable. The rotary plate is provided with a region in which the container rack can be installed inside a region of passage of the reaction containers, when turning, and is provided to be turnable where the light-shielded room is in a closed state.
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公开(公告)号：US20170234899A1
公开(公告)日：2017-08-17
申请号：US15587112
申请日：2017-05-04
发明人： Michael Eberhardt , Martin Mueller , Sebastian Wiessner , Thomas Moix , Guillaume Ding , Jurjen Zoethout
IPC分类号： G01N35/00
CPC分类号： G01N35/00584 , G01N35/04 , G01N2035/0422 , G01N2035/0467 , G01N2035/0489
摘要： The invention concerns a laboratory product transport element for a laboratory transport system with an energy receiver and/or energy accumulator to provide drive power, at least one signal receiver to receive control signals, a control unit to generate drive signals as a function of at least one control signal obtained from the at least one signal receiver, movement devices for independent movement of the laboratory product transport element on a transfer path as a function of the drive signals of the control unit, in which the drive devices are driven by the drive power and at least one holder to hold a laboratory product being transported. The invention also concerns a laboratory transport system with at least one laboratory product transport element according to an embodiment of the invention and a transfer path arrangement. The invention also concerns methods for operation of laboratory transport systems according to an embodiment of the invention.
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