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    METHOD AND SYSTEM OF ARRAY IMAGING
    21.
    发明申请
    METHOD AND SYSTEM OF ARRAY IMAGING 审中-公开
    阵列成像的方法与系统

    公开(公告)号：US20100032547A1

    公开(公告)日：2010-02-11

    申请号：US12567618

    申请日：2009-09-25

    Applicant: David R. Walt ,  Sandra Bencic-Nagale

    Inventor： David R. Walt ,  Sandra Bencic-Nagale

    IPC: G01N21/00 ,  H01L31/0232

    CPC classification number: G01J3/2803 ,  G01J3/02 ,  G01J3/0213 ,  G01J3/0229 ,  G01J3/10 ,  G01J3/4406 ,  G01J2001/0276 ,  G01N21/6428 ,  G01N21/6458 ,  G01N2021/6441 ,  G01N2021/6484 ,  G01N2201/08 ,  G01N2201/088

    Abstract: The present invention relates to a method and system of array imaging that extends or maximizes the longevity of the sensor array by minimizing the effects of photobleaching. The imaging system has a light source, a variable exposure aperture, and a variable filter system. The system extends the longevity of sensors by (1) using the variable exposure aperture to selectively expose sections of the sensor array containing representative numbers of each type of sensor, and/or (2) using the variable filter system to control the intensity of the excitation light, providing only the intensity required to induce the appropriate excitation and increasing that intensity over time as necessary to counteract the effects of photobleaching.

    Abstract translation: 本发明涉及阵列成像的方法和系统，该方法和系统通过最小化光漂白的影响来延长或最大化传感器阵列的寿命。 成像系统具有光源，可变曝光孔径和可变过滤器系统。 该系统通过（1）使用可变曝光孔径来延长传感器的寿命，以选择性地暴露包含每种类型的传感器的代表数的传感器阵列的部分，和/或（2）使用可变过滤器系统来控制传感器的强度 激发光，仅提供诱导适当激发所需的强度，并随时间增加强度以抵消光漂白的影响。

    Apparatus and method for chemical and biological sensing
    22.
    发明申请
    Apparatus and method for chemical and biological sensing 审中-公开
    化学和生物传感的装置和方法

    公开(公告)号：US20080116361A1

    公开(公告)日：2008-05-22

    申请号：US11600386

    申请日：2006-11-16

    Applicant: Glen A. Sanders ,  Chellappan Narayanan

    Inventor： Glen A. Sanders ,  Chellappan Narayanan

    IPC: G01N21/75

    CPC classification number: G01N21/7746 ,  G01D5/35345 ,  G01N2021/7716 ,  G01N2201/0612 ,  G01N2201/088 ,  G02B6/2934

    Abstract: Apparatus and method are provided for chemical and biological agent sensing. The sensing apparatus includes a resonator having a resonance frequency and one or more optical fiber coils. The optical fiber coil has a permeable cladding and an indicator embedded in the cladding that reacts to an agent (e.g., a chemical or biological substance). The resonator circulates light through the coil and produces a resonance shape centered at the resonance frequency and measured via the input light. A predetermined change in the resonance shape indicates a presence of the agent in the environment.

    Abstract translation: 提供了用于化学和生物试剂感测的装置和方法。 感测装置包括具有共振频率的谐振器和一个或多个光纤线圈。 光纤线圈具有可渗透的包层和嵌入包层中的与试剂（例如化学或生物物质）反应的指示剂。 谐振器通过线圈循环光，并产生以谐振频率为中心的谐振形状，并通过输入光测量。 共振形状的预定变化表示在环境中存在该试剂。

    Fiber optic multitasking probe
    23.
    发明授权
    Fiber optic multitasking probe 失效
    光纤多任务探头

    公开(公告)号：US06514277B1

    公开(公告)日：2003-02-04

    申请号：US09329998

    申请日：1999-06-11

    Applicant: Lothar Lilge ,  David Walsh

    Inventor： Lothar Lilge ,  David Walsh

    IPC: A61B1822

    CPC classification number: G01N21/7703 ,  A61N5/0601 ,  A61N5/062 ,  G01N21/6428 ,  G01N2201/0846 ,  G01N2201/088

    Abstract: A multitasking optical fiber probe for collecting dosimeter information from more than one position in a sample. The basic principle of the present invention involves using one or more different sensor zones along the length of the fiber each with a different photoactive constituent having a sufficiently unique emission spectra (spectral or temporal) to enable deconvolution of the emission spectra by the computer and therefore correlation of the detected parameter with the position of the sensor zone along the length of the optical fiber. In the broadest form of the invention the probe is embodied by only one sensor zone located at some point along the length of the fiber spaced away from the end face of the fiber. Probes are provided in which multiple sensor zones are disposed along the length of the fiber and photoactive constituents with sufficiently unique emission spectra (intensity and/or spectral shape which convey the optical information) are used in the different sensor zones so that the different spectra can be deconvoluted so that the contributions from the various etch zones can be distinguished. More than one different photoactive constituent could be incorporated into a single sensor zone for measuring several factors in the vicinity of the sensor zone. In photodynamic therapy applications the probe is isotropic in response and can be employed for all light (300 to 900nm) based medical diagnostics and therapeutics. As an extension the probe can include photosensitiser and molecular oxygen concentrations dosimetry to be used for photodynamic therapy (PDT) treatment monitoring, dosimetry and planning utilizing a mathematical model describing tissue response to PDT.

    Abstract translation: 一种用于从样品中多于一个位置收集剂量计信息的多任务光纤探针。 本发明的基本原理涉及沿着纤维的长度使用一个或多个不同的传感器区域，每个具有不同的光活性组分具有足够独特的发射光谱（光谱或时间），以使计算机能够对发射光谱进行去卷积，因此 检测参数与传感器区域沿着光纤长度的位置的相关性。 在本发明的最广泛形式中，探针仅通过位于沿纤维长度的某一点处的一个传感器区域，该距离与纤维的端面间隔开。 提供探针，其中多个传感器区域沿着纤维的长度设置，并且光​​活性组分具有足够独特的发射光谱（传递光学信息的强度和/或光谱形状）被用于不同的传感器区域，使得不同的光谱可以 被去卷积，从而可以区分来自各种蚀刻区域的贡献。 可以将多于一种不同的光活性成分结合到单个传感器区域中，以测量传感器区域附近的几个因素。 在光动力学治疗应用中，探针是各向同性的响应，可用于所有基于光（300至900nm）的医疗诊断和治疗。 作为延伸，探针可以包括用于光动力治疗（PDT）治疗监测，剂量测定和计划的光敏剂和分子氧浓度剂量学，其使用描述对PDT的组织反应的数学模型。

    DAMAGE DETECTION SYSTEM AND DAMAGE DETECTION METHOD
    24.
    发明申请
    DAMAGE DETECTION SYSTEM AND DAMAGE DETECTION METHOD 审中-公开

    公开(公告)号：US20190170656A1

    公开(公告)日：2019-06-06

    申请号：US16257550

    申请日：2019-01-25

    Applicant: SUBARU CORPORATION

    Inventor： Masakatsu ABE

    IPC: G01N21/88

    CPC classification number: G01N21/8806 ,  G01B11/00 ,  G01N2021/8845 ,  G01N2201/088

    Abstract: According to one implementation, a damage detection system includes optical paths, a light source, a photodetector, and a signal processing system, a signal processing system. The optical paths propagate lights in at least three different directions. The optical paths have at least two paths per one direction. The light source makes the lights incident on one ends of the optical paths respectively. The photodetector detects the lights output from other ends of the optical paths. The signal processing system specifies at least one location of damage based on optical detection signals detected by the photodetector.

    TESTING OF AN INDUSTRIAL STRUCTURE
    30.
    发明申请
    TESTING OF AN INDUSTRIAL STRUCTURE 审中-公开
    工业结构测试

    公开(公告)号：US20160377528A1

    公开(公告)日：2016-12-29

    申请号：US15039788

    申请日：2014-11-27

    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

    Inventor： Bastien CHAPUIS

    IPC: G01N21/17 ,  G01M5/00 ,  G01N29/24 ,  G01D5/353 ,  G01N29/06 ,  G01N29/07

    CPC classification number: G01N21/1702 ,  G01D5/35316 ,  G01M5/0008 ,  G01M5/0016 ,  G01M5/0025 ,  G01M5/0091 ,  G01M11/085 ,  G01N29/0672 ,  G01N29/07 ,  G01N29/2418 ,  G01N2021/1706 ,  G01N2201/088 ,  G01N2201/1211 ,  G01N2291/011 ,  G01N2291/2694

    Abstract: A method and a device for analyzing a structure by tomography and diffuse acousto-elastic field correlation are provided. An optical fiber comprising a plurality of measurement points of FBG (Fiber Bragg Grating) type, comprising sensors of Bragg grating type, is deployed in or on the structure to be analyzed. The method comprises the emission of light, into the optical fiber, and the measurement by correlation for each pair of FBG sensors. In a development, a prior imaging of the structure is performed by reconstruction of the velocities of propagation. Other developments comprise: the determination of the positions of the FBG sensors, the calibration of the tomography, the rosette configuration of the sensors forming the measurement points, the use of a plurality of optical fibers, of multiplexers, of lasers, of optical circulators, of omnidirectional optical sensors, of active noise sources, such as piezoelectric transducers, incorporated or not in the structure.

    Abstract translation: 提供了一种通过断层扫描和扩散声弹性场相关分析结构的方法和装置。 包括布拉格光栅型传感器的FBG（光纤布拉格光栅）类型的多个测量点的光纤部署在要分析的结构中或其上。 该方法包括将光发射到光纤中，并且通过每对FBG传感器的相关性进行测量。 在一个发展中，通过重建传播速度来执行该结构的先前成像。 其他发展包括：确定FBG传感器的位置，层析成像的校准，形成测量点的传感器的玫瑰花结构，使用多个光纤，光学循环器的激光器的多路复用器， 的全向光学传感器，诸如压电换能器的有源噪声源，结合在一起或不结合。

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