公开(公告)号：US20050004147A1

公开(公告)日：2005-01-06

申请号：US10903059

申请日：2004-08-02

申请人： Shigeki Hibi ,  Yorihisa Hoshino ,  Tatsuya Yoshiuchi ,  Kogyoku Shin ,  Kouichi Kikuchi ,  Motohiro Soejima ,  Mutsuko Tabata ,  Yoshinori Takahashi ,  Hisashi Shibata ,  Takayuki Hida ,  Tetsuya Hirakawa ,  Mitsuhiro Ino

发明人： Shigeki Hibi ,  Yorihisa Hoshino ,  Tatsuya Yoshiuchi ,  Kogyoku Shin ,  Kouichi Kikuchi ,  Motohiro Soejima ,  Mutsuko Tabata ,  Yoshinori Takahashi ,  Hisashi Shibata ,  Takayuki Hida ,  Tetsuya Hirakawa ,  Mitsuhiro Ino

IPC分类号： A61P1/04 ,  A61P1/08 ,  A61P1/10 ,  A61P1/12 ,  A61P1/14 ,  A61P9/04 ,  A61P9/10 ,  A61P9/12 ,  A61P11/00 ,  C07D471/14 ,  C07D487/14 ,  C07D491/14 ,  A61K31/519

CPC分类号： C07D471/14 ,  C07D487/14 ,  C07D491/14

摘要： The present invention provides a novel compound having an excellent corticotrophin-releasing-factor receptor antagonistic activity. That is, it provides a compound represented by the following formula, a pharmacologically acceptable salt thereof or hydrates thereof. Wherein A, B and D are the same as or different from each other and each represents a group represented by the formula —(CR1R2)m— (wherein R1 and R2 are the same as or different from each other and each represents a C1-6 alkyl group etc.), —NR3— (wherein R3 represetns hydrogen etc.) etc.; E and G are the same as or different from each other and each represents a group represented by the formula —(CR6R7)p— (wherein R6 and R7 are the same as or different from each other and each represents hydrogen etc.; and p represents an integer of 0, 1 or 2); J represents a carbon atom or nitrogen atom, each substituted with C1-6 alkyl group optionally substituted with a halogen atom, etc.; K and L are the same as or different from each other and each represents carbon atom or nitrogen atom; M means hydrogen, a halogen atom, an optionally substituted C1-6 alkyl group etc.; and the partial structure means a single or double bond.

摘要翻译： 本发明提供具有优异的促肾上腺皮质激素释放因子受体拮抗活性的新型化合物。 也就是说，它提供由下式表示的化合物，其药理学上可接受的盐或其水合物。 其中A，B和D彼此相同或不同，并且各自表示由式 - （CR 1 R 2）m - 表示的基团（其中R 1和R 2为 相同或不同，各自表示C1-6烷基等），-NR 3 - （其中R 3表示氢等）等; E和G彼此相同或不同，并且各自表示由下式表示的基团 - （CR 6 R 7）p - （其中R 6和R 7与 彼此不同，各自表示氢等; p表示0,1或2的整数）; J表示碳原子或氮原子，各自被任选被卤素原子取代的C 1-6烷基取代; K和L彼此相同或不同，各自表示碳原子或氮原子; M表示氢，卤原子，任意取代的C 1-6烷基等; 并且部分结构是指单键或双键。

公开(公告)号：US06815993B1

公开(公告)日：2004-11-09

申请号：US10110203

申请日：2002-04-17

申请人： Hisato Ishimoto ,  Yoshinori Takahashi

发明人： Hisato Ishimoto ,  Yoshinori Takahashi

IPC分类号： H03H1116

CPC分类号： H03H11/22 ,  H03D7/1433 ,  H03D7/1441 ,  H03D7/165 ,  H03H7/21

摘要： In a &pgr;/2 phase shifter, first and second signals and first and second inverted signals are produced based on input signals. The first and second signals have the same amplitude and are out of phase from each other, and the first and second inverted signals respectively correspond to the first and second signals with their respective phases inverted. A first output signal is produced by adding the first signal and the second signal, and a second output signal is produced by adding the first signal and the second inverted signal. Since the first and second signals have the same amplitude, the first output signal and the second output signal respectively correspond to diagonal lines of a rhombus formed by a vector representing the first signal and a vector representing the second signal. Accordingly, the phase difference between the first and second output signals of the &pgr;/2 phase shifter is accurately set to &pgr;/2 even when the phase difference between the first and second signals is not &pgr;/2.

摘要翻译： 在π/ 2移相器中，基于输入信号产生第一和第二信号以及第一和第二反相信号。 第一信号和第二信号具有相同的幅度并且彼此异相，并且第一和第二反相信号分别对应于其相应相位反转的第一和第二信号。 通过将第一信号和第二信号相加来产生第一输出信号，并且通过将第一信号和第二反相信号相加来产生第二输出信号。 由于第一和第二信号具有相同的幅度，所以第一输出信号和第二输出信号分别对应于由表示第一信号的矢量和表示第二信号的矢量形成的菱形的对角线。 因此，即使当第一和第二信号之间的相位差不是pi / 2时，pi / 2移相器的第一和第二输出信号之间的相位差被精确地设置为pi / 2。

公开(公告)号：US06767622B2

公开(公告)日：2004-07-27

申请号：US09926006

申请日：2001-10-31

申请人： Kazuyuki Hada ,  Yoshinori Takahashi

发明人： Kazuyuki Hada ,  Yoshinori Takahashi

IPC分类号： B32B300

CPC分类号： C08J5/18 ,  A61F13/42 ,  A61F13/51462 ,  A61F13/51496 ,  C08J2323/08 ,  Y10T428/249956 ,  Y10T428/249967 ,  Y10T428/24998 ,  Y10T428/249993

摘要： The present invention provides a porous polyolefin film abounding in air permeability and moisture permeability and having extremely high degree of light transmission and tear strength, a process for producing same and intended use thereof. This porous polyolefin film is produced, for example, by stretching an unstretched polyolefin film having a resin composition of 100 parts by weight of polyolefin, 50-150 parts by weight of an inorganic filler having a 50% median diameter of at least 2 &mgr;m but less than 7 &mgr;m measured according to the light-scattering method, and 2-20 parts by weight of a wax of polyolefin series in at least uniaxial direction at an area magnification of 1.1-1.5 times, and possesses physical properties of a water vapor transmission rate of at least 1000 g/m2·24 hrs., a light transmission of at least 65%, and a tear strength of at least 0.6 N.

摘要翻译： 本发明提供一种多孔聚烯烃膜，其具有透气性和透湿性，并且具有极高的透光和撕裂强度，其制造方法及其用途。 该多孔聚烯烃膜例如通过拉伸具有100重量份聚烯烃的树脂组合物的未拉伸聚烯烃膜，50-150重量份的50％中值粒径至少为2μm的无机填料制成，但是 根据光散射法测定小于7μm，并且以至少单轴方向的2-20重量份的聚烯烃系列以1.1-1.5倍的面积放大倍数，并且具有水蒸汽透过率的物理性质 速率至少为1000g / m 2 .24小时，透光率至少为65％，撕裂强度至少为0.6N。

公开(公告)号：US06750720B1

公开(公告)日：2004-06-15

申请号：US10149390

申请日：2002-06-12

申请人： Kazutomi Mori ,  Shintarou Shinjo ,  Hiroyuki Joba ,  Yoshinori Takahashi ,  Yukio Ikeda ,  Tadashi Takagi

发明人： Kazutomi Mori ,  Shintarou Shinjo ,  Hiroyuki Joba ,  Yoshinori Takahashi ,  Yukio Ikeda ,  Tadashi Takagi

IPC分类号： H03F304

CPC分类号： H03F1/0261 ,  H03F1/302 ,  H03F3/19 ,  H03F3/343

摘要： Between resistors 13, 14 and an NPN bipolar transistor 12 are interposed PNP bipolar transistors 21, 22 forming a current mirror 20 that uses a collector current of the NPN bipolar transistor 12 as a reference current, and determines a collector current of an NPN bipolar transistor 11. This makes possible to design a size ratio A of the PNP bipolar transistors 21, 22 so as to approximate a voltage drop &Dgr;Vb to a value close to zero, and to suppress the voltage drop &Dgr;Vb of the base voltage Vb accordingly to achieve a high power output and high efficiency when a high frequency input signal Pin increases and generates a base rectified current.

摘要翻译： 在电阻器13,14和NPN双极晶体管12之间插入形成使用NPN双极晶体管12的集电极电流作为参考电流的电流镜20的PNP双极晶体管21,22，并且确定NPN双极晶体管的集电极电流 这使得可以设计PNP双极晶体管21,22的尺寸比A，以将电压降ΔVV近似为接近于零的值，并且相应地抑制基极电压Vb的电压降DeltaVb以实现 当高频输入信号Pin增加并产生基极整流电流时，高功率输出和高效率。

公开(公告)号：US06323592B1

公开(公告)日：2001-11-27

申请号：US09274206

申请日：1999-03-23

申请人： Yoshinori Takahashi ,  Tsuyoshi Oyaizu ,  Hidemi Matsuda

发明人： Yoshinori Takahashi ,  Tsuyoshi Oyaizu ,  Hidemi Matsuda

IPC分类号： H01J2992

CPC分类号： H01J29/868 ,  H01J9/20 ,  H01J2229/0015 ,  H01J2229/8636

摘要： Disclosed is a conductive antireflection film comprising a laminate structure consisting of a conductive layer and an insulating covering layer covering the surface of the conductive layer and a conductive member connected at one end to the conductive layer and exposed at the other end to the outside. The conductive member is brought into contact with an electrolytic solution so as to control the state of the metal contained in the conductive layer, making it possible to prevent effectively an electromagnetic wave from leaking to the outside and to obtain a clear image of a high contrast.

摘要翻译： 公开了一种导电性抗反射膜，其包括由导电层和覆盖导电层的表面的绝缘覆盖层构成的层压结构，以及导电构件，其一端连接到导电层并且在另一端暴露于外部。 导电部件与电解液接触，以控制包含在导电层中的金属的状态，使得可以有效地防止电磁波泄漏到外部并获得高对比度的清晰图像 。

公开(公告)号：US6060485A

公开(公告)日：2000-05-09

申请号：US181091

申请日：1998-10-28

申请人： Terumitsu Kaihoh ,  Tomomi Okada ,  Yoshinori Takahashi ,  Hiroyuki Mizuno ,  Haruyoshi Honda ,  Susumu Sato

发明人： Terumitsu Kaihoh ,  Tomomi Okada ,  Yoshinori Takahashi ,  Hiroyuki Mizuno ,  Haruyoshi Honda ,  Susumu Sato

IPC分类号： C07D211/58 ,  C07D211/94 ,  C07D401/12 ,  A61K31/445

CPC分类号： C07D401/12 ,  C07D211/58 ,  C07D211/94

摘要： Described is an arylacetic amide derivative represented by the following formula (1): ##STR1## wherein R.sup.1 represents an aryl group or the like, R.sup.2 and R.sup.3 each independently represents an alkyl group, a cycloalkyl group or the like, and R.sup.4 represents an aralkyl group, an alkyl group or the like; or salt thereof. The compound according to the present invention has both excellent anticholinergic action and calcium antagonism and at the same time has high selectivity to bladder, so that it is useful as a preventive or remedy for urinary disorders.

摘要翻译： 描述了由下式（1）表示的芳基乙酰胺衍生物：其中R 1表示芳基等，R 2和R 3各自独立地表示烷基，环烷基等，R 4表示芳烷基， 烷基等; 或其盐。 根据本发明的化合物具有优异的抗胆碱能作用和钙拮抗作用，同时对膀胱具有高选择性，因此可用作尿障碍的预防或治疗方法。

公开(公告)号：US6022433A

公开(公告)日：2000-02-08

申请号：US157530

申请日：1998-09-21

申请人： Minoru Ota ,  Yoshinori Takahashi ,  Yoshihiko Higuchi ,  Takashi Tsujii

发明人： Minoru Ota ,  Yoshinori Takahashi ,  Yoshihiko Higuchi ,  Takashi Tsujii

IPC分类号： B29C65/00 ,  B29C65/02 ,  B29C65/06 ,  B29C65/08 ,  G01N33/52 ,  B32B31/16

CPC分类号： G01N33/525 ,  B29C65/08 ,  B29C65/082 ,  B29C66/472 ,  B29C66/7392 ,  B29C66/7487 ,  B29C65/0618 ,  B29C66/21 ,  B29C66/303 ,  B29C66/30326 ,  B29C66/71 ,  B29C66/727 ,  B29C66/729 ,  B29C66/73921 ,  B29K2313/00 ,  B29K2705/00 ,  B29K2709/02 ,  B29K2709/08 ,  B29K2711/00 ,  B29K2711/12 ,  B29K2711/14

摘要： A method for fixing a reagent layer directly onto a supporting base plate in the preparation of a dry analysis kit for determining a specific component in a liquid specimen wherein at least one of the reagent layer and the base plate is a thermoplastic resin, and which comprises the steps of:placing the reagent layer in contact with the base plate and externally applying ultrasonic vibration and pressure to the two layers to generate frictional heat thereby to melt the surface of the thermoplastic resin;applying pressure to make the molten surface of thermoplastic resin bite the non-thermoplastic material or to integrate the surfaces of thermoplastic layer and base plate; andremoving the ultrasonic vibration and pressure.

摘要翻译： 一种将试剂层直接固定在支撑基板上的方法，用于制备用于确定液体试样中的特定成分的干燥分析试剂，其中至少一个试剂层和基板是热塑性树脂，并且包括 步骤：将试剂层与基板接触并向外部施加超声波振动和压力以产生摩擦热，从而熔化热塑性树脂的表面; 施加压力以使热塑性树脂的熔融表面咬住非热塑性材料或将热塑性层和基板的表面相结合; 并移除超声波振动和压力。