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    Device for treating cancer and non-malignant tumors and methods
    34.
    发明授权
    Device for treating cancer and non-malignant tumors and methods 失效
    用于治疗癌症和非恶性肿瘤的装置及方法

    公开(公告)号：US5472441A

    公开(公告)日：1995-12-05

    申请号：US208676

    申请日：1994-03-11

    Applicant: Stuart D. Edwards ,  Ronald G. Lax

    Inventor： Stuart D. Edwards ,  Ronald G. Lax

    IPC: A61B18/00 ,  A61B18/14 ,  A61B18/18 ,  A61M1/00 ,  A61M3/02 ,  A61M25/00 ,  A61N5/02 ,  A61N5/04 ,  A61B17/36

    CPC classification number: A61B18/1477 ,  A61B18/1482 ,  A61B18/18 ,  A61B18/1815 ,  A61N5/02 ,  A61N5/045 ,  A61B18/14 ,  A61B18/1402 ,  A61B18/1492 ,  A61B2018/00011 ,  A61B2018/00196 ,  A61B2018/00452 ,  A61B2018/00476 ,  A61B2018/00577 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00726 ,  A61B2018/00761 ,  A61B2018/00779 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1425 ,  A61B2018/1435 ,  A61B2018/162 ,  A61B2218/002 ,  A61M25/007 ,  A61M3/0279 ,  A61N5/04

    Abstract: A method of this invention for treating body tissues containing cancerous cells or non-malignant tumors with RF ablation, alone or in combination with systemic or localized chemotherapy comprising introducing a stylet comprising an electrode surface and a sleeve longitudinally moveable thereon into the vicinity of the body tissues, retracting the sleeve from a portion of the electrode surface, and supplying RF power to the electrode surface sufficient to heat the tissue to a temperature of above about 45.degree. C. for a time to cause reduction of tissue mass in the vicinity of the electrode. The RF power supplied to the electrode surface is sufficient to effect a desiccated fluid diffusion barrier capsule surrounding the body tissue being treated. The stylet can include a hollow tube having fluid distribution ports therein, and the method can include the step of passing fluid through one or more distribution ports into the body tissue being treated. The fluid can be saline or a chemotherapeutic fluid such as liquid or gas containing a cytotoxic agent, for example. The fluid can be administered in a variety of procedures. The fluid can be passed through a distribution port into the body tissue before, during and/or after the RF power is supplied to the electrode surface, for example. Preferably, the fluid is introduced after a barrier capsule has been formed. The devices comprises electrodes havming a hollow core and a closed sharpened distal tip. The electrode has a plurality of fluid distribution ports therein for distribution of fluid treatment agents into the tissue.

    Abstract translation: 本发明的方法，用于单独或与全身或局部化疗组合，用RF消融治疗含有癌细胞或非恶性肿瘤的身体组织，包括将包含电极表面和纵向可移动到其上的套管引入身体附近 组织，从电极表面的一部分缩回套筒，并将RF功率提供给电极表面，足以将组织加热至高于约45℃的温度一段时间，以使组织块在附近的 电极。 提供给电极表面的RF功率足以实现围绕被处理的身体组织的干燥的流体扩散阻挡胶囊。 探针可以包括其中具有流体分配端口的中空管，并且该方法可以包括使流体通过一个或多个分配端口进入被处理的身体组织的步骤。 流体可以是例如盐水或化疗液体，例如含有细胞毒性剂的液体或气体。 流体可以以各种方法给药。 例如，在将RF功率提供给电极表面之前，期间和/或之后，流体可以通过分配端口进入身体组织。 优选地，在形成阻挡胶囊之后引入流体。 这些装置包括电极，该电极覆盖中空芯和封闭的锋利的远端尖端。 电极在其中具有多个流体分配端口，用于将流体处理剂分配到组织中。

    Articulated systems for cardiac ablation
    35.
    发明授权
    Articulated systems for cardiac ablation 失效
    用于心脏消融的铰接系统

    公开(公告)号：US5368592A

    公开(公告)日：1994-11-29

    申请号：US126126

    申请日：1993-09-23

    Applicant: Roger A. Stern ,  Stuart D. Edwards ,  Jerome Jackson

    Inventor： Roger A. Stern ,  Stuart D. Edwards ,  Jerome Jackson

    IPC: A61M25/01 ,  A61N1/40

    CPC classification number: A61M25/0147 ,  Y10T403/32311

    Abstract: An improved assembly for steering and orienting a functional element at the distal end of a catheter tube holds the functional element with its major axis aligned with the axis of the catheter tube for convenient steering to a tissue site. The mechanism can also pivot the functional element in response to an external force to orient the major axis of the functional element generally parallel to the plane of the tissue site, without bending the catheter tube.

    Abstract translation: 用于在导管管的远端处转向和定向功能元件的改进的组件保持功能元件，其主轴与导管管的轴线对准，以便于转向组织部位。 机构还可以响应于外力使功能元件枢转，以使功能元件的长轴大致平行于组织部位的平面定向，而不弯曲导管。

    Valve mapping catheter
    36.
    发明授权
    Valve mapping catheter 失效
    阀门定位导管

    公开(公告)号：US5275162A

    公开(公告)日：1994-01-04

    申请号：US982233

    申请日：1992-11-25

    Applicant: Stuart D. Edwards ,  Russell B. Thompson ,  Rand T. Pugmire

    Inventor： Stuart D. Edwards ,  Russell B. Thompson ,  Rand T. Pugmire

    IPC: A61B5/042

    CPC classification number: A61B5/042 ,  A61B5/0422 ,  A61B2562/0209 ,  A61B2562/043

    Abstract: A method and apparatus for contacting heart valve tissue with a catheter tip electrode adapted for atrioventricular (AV) node mapping and modification is provided. The tip is conformed to rest stably and comfortably on a cardiac valve such as the mitral or tricuspid valve. The tip has a peanut shape consisting of two electrode lobes joined by a narrower connecting piece. The tip rests on the valve at the connecting piece and is secured by the adjoining lobes. The connecting piece itself may either be insulating or electrically conductive. The catheter may also include standard mapping and/or pacing electrodes. The catheter may further include a steering mechanism for positioning the catheter at various treatment sites in the heart.

    Abstract translation: 提供一种用于使心脏瓣膜组织与适用于房室（AV）节点映射和修改的导管尖端电极接触的方法和装置。 尖端符合在诸如二尖瓣或三尖瓣的心脏瓣膜上稳定和舒适地平稳。 尖端具有由两个由较窄连接件连接的电极凸片组成的花生形状。 尖端位于连接件上的阀上，并由相邻的凸角固定。 连接件本身可以是绝缘的或导电的。 导管还可以包括标准贴图和/或起搏电极。 导管还可以包括用于将导管定位在心脏中的各种治疗部位的转向机构。

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