摘要:
The present invention provides NOS inhibitors such as iNOS inhibitors, or a pharmaceutically acceptable salt, ester, prodrug, complex, solvate, hydrate, or isomer thereof, in any crystalline form or in amorphous form. The inhibitors include 1,1 or 1,2 substituted-ethyl carbamimido thioates, cyclic compounds substituted with a carbamimidoyl sulfanylethylphenyl group and a carbamimidoylsulfanyl group, compounds substituted with a carbamimidoyl sulfanylethyl phenylmethyl group, bis-carbamimidoylsulfanylethyl substituted compounds, 2-propoxypyridine derivatives, alkylamine or heteroalkylamine derivatives, n-aminoethyl n-phenyl amine derivatives, and saturated heterocyclic fused benzene derivatives. Pharmaceutical products comprising the NOS inhibitors such as iNOS inhibitors and the applications thereof in prophylaxis and/or treatment of inflammatory diseases, and proliferative diseases such as cancer including gastro-intestinal, colorectal, gynecological, pancreatic, head and neck, esophageal, breast, lung, and central nervous system tumors, among others, are also provided.
摘要:
Provided are a nonaqueous electrolyte capable of providing a nonaqueous electrolyte energy storage device with reduced direct current resistance and an increased capacity retention ratio after charge-discharge cycles, a nonaqueous electrolyte energy storage device including such a nonaqueous electrolyte, and a method for producing such a nonaqueous electrolyte energy storage device. One mode of the present invention is a nonaqueous electrolyte for an energy storage device, containing an additive represented by the following Formula (1) or Formula (2). In Formula (1), R1 to R4 are each independently a hydrogen atom or a group represented by —NRa2, —ORa, —SRa, etc., with the proviso that at least one of R1 to R4 is a group represented by —ORa, —SRa, —COORa, —CORa, —SO2Ra, or —SO3Ra. In Formula (2), R5 to R7 are each independently a hydrogen atom or a group represented by —NRb2, —ORb, or —SRb, with the proviso that at least one of R5 to R7 is a group represented by —SRb.
摘要:
The invention relates to the field of pesticide technology, and in particular a type of carboxylic acid derivative-substituted iminoaryl compound, preparation method, herbicidal composition and use thereof. The compound, as shown in general formula I: wherein, Q represents Y represents halogen, haloalkyl or cyano; Z represents halogen; M represents CH or N; W represents OX5, SX5 or N(X5)2; X represents —CX1X2-(alkyl)n-, -alkyl-CX1X2-(alkyl)n- or —(CH2)r—; X3 and X4 each independently represent O, S, NH or N-alkyl, etc. The compound has excellent herbicidal activity against gramineous weeds, broadleaf weeds, cyperaceae weeds and so on even at low application rates, and has high selectivity for crops.
摘要:
A semiconductor device and manufacturing method therefor, provided with the aims of constraining resin burr formation while having good electric connectivity and joining strength, and LED device, provided with the aim of improving adhesion between silicon resin and leads while having good luminescent characteristics.
摘要:
The instant invention relates to storage stable solutions of optical brighteners based on certain salt forms of anilino-substituted bistriazinyl derivatives of 4,4′-diaminostilbene-2,2′-disulphonic acid and of organic acids which do not need extra solubilizing additives.
摘要:
The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 1 or prokinetin 1 receptor mediated disorders.
摘要:
The present invention relates to a thiol compound derivative represented by the following formula (1), a curable composition containing the derivative, and a molded product made of the composition. More particularly, the invention relates to a thiol compound derivative which is added to a polymer having reactivity to a thiol derivative substituent to provide a curable composition, a curable composition containing the derivative and a crosslinkable halogen-containing crosslinking polymer, and a crosslinked molded product of the composition. wherein X1, X2 and X3 are each a group represented by the following formula (2).
摘要:
Compounds of formula wherein Rf is a (per)fluoropolyoxyalkylene chain having a number average molecular weight in the range 500-10,000; W1, W2, equal to or different from each other, are —F or —CF3; T1 is equal to —CHAa—Ba (CH2CH2O)na— wherein Aa=H, CF3; Ba=O, S, NH; na=0 or an integer between 1 and 6; T2 is equal to —F, —CF3, —C2 F5, —(C2 F4) Cl, or a group of formula: Q1, Q2 equal to or different from each other, are a chain of formula -T1-l -CFW1—O—Rf—CFW2-T′2, wherein: T′2 is equal to —F, —CF3, —C2 F5, —(C2F4) Cl; or is a group of formula: wherein B is equal to O, S, NH; R1, R2, R3, R4, R5 equal to or different from each other are selected from H, F, NO2, CN, C1-C8 perfluoroalkyl, carboxyl, phenyl (Ph), O- Ph, NH-Ph, S-Ph; wherein B is equal to O, S, NH; R1, R2, R3, R4, R5 equal to or different from each other are selected from H, F, NO2, CN, C1-C8 perfluoroalkyl, carboxyl, phenyl (Ph), O- Ph, NH-Ph, S-Ph; with the proviso that at least one of Q1 and Q2a is equal to:
摘要翻译:下式化合物其中R ff是数均分子量在500-10,000范围内的(全)氟代聚氧亚烷基链; W 1,W 2,...等于或不同的基团是-F或-CF 3 N; T 1等于-CHA A 1 H 2 CH 2(CH 2 CH 2)2 CH 2 其中A a为H,CF 3 N; B = O,S,NH; na = 0或1和6之间的整数; T 2等于-F,-CF 3,-C 2 H 5, - (C 1 -C 3) 或者每个等于或不同于下式的基团:Q 1,Q 2,...,N 2, 另一方面,是一种式-T 1-1 -CFW-1 -F 1 -CFW 2 - - - SIPO < T'2,其中:T'2等于-F,-CF 3,-C 2, F 5, - (C 2 F 4)Cl; 或者是下式的基团:其中B等于O,S,NH; 等于或不同的R 1,R 2,R 3,R 4,R 5选自H,F,NO 2,CN,C 1 -C 8 全氟烷基,羧基,苯基(Ph),O- Ph,NH-Ph,S-Ph; 其中B等于O,S,NH; 等于或不同的R 1,R 2,R 3,R 4,R 5选自H,F,NO 2,CN,C 1 -C 8 全氟烷基,羧基,苯基(Ph),O- Ph,NH-Ph,S-Ph; 条件是Q 1和Q 2中的至少一个a等于:
摘要:
Disclosed are 3-heterocyclyl substituted benzoic acid derivatives of general formula (I), in which the variables R1 to R8 and X have the meanings indicated in claim 1, and the use thereof as herbicides or for desiccating/defoliating plants.
摘要:
Triazine derivatives of general formula (I); and recording materials excellent in the storage stability of developed images, particularly the resistance thereof to plasticizers.