Abstract:
The present invention relates to uses of Macrolactin A produced by Bacillus polyfermenticus KJS-2 (KCCM 10769P), which is a new bacillus strain, as an antibiotic. Macrolactin A of the present invention, which is produced by Bacillus polyfermenticus KJS-2, shows a broad spectrum of antibiotic activity against a variety of microorganisms and fungi, and is proved to be very efficient for the inhibition of particularly vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus Aureus (MRSA) that are multidrug-resistant bacteria. The antibiotic Macrolactin A produced by Bacillus polyfermenticus KJS-2, can be used as an excellent antibiotic against vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus Aureus (MRSA), and thus the present invention is a very useful invention for medical industry.
Abstract:
The present invention relates to salts of a pyrrolopyrimidinone derivative having superior PDE-5 inhibition activity and a process for preparing the same. More particularly, the present invention relates to a crystalline acid addition salt prepared by reacting a pyrrolopyrimidinone derivative with an acid selected from gentisic acid, maleic acid, citric acid, fumaric acid and tartaric acid. With no hygroscopic property and superior long-term storage stability, photostability and thermal stability, the salts of the pyrrolopyrimidinone derivative are appropriate to be prepared into medications and, with superior PDE-5 inhibition activity, are useful for the treatment and prevention of erectile dysfunction, pulmonary arterial hypertension, chronic obstructive pulmonary disease, benign prostatic hypertrophy and lower urinary tract diseases.
Abstract:
This application relates to a novel benzo-heterocycle derivative and more particularly, it relates a composition for preventing and treating cancer or for inhibiting metastasis comprising benzo-heterocycle derivative or pharmaceutically acceptable salts thereof as an active ingredient. The present inventors confirmed that KRS has an effect on cancer metastasis by facilitating cancer (or tumor) cell migration through interaction with 67LR, and also found that a substance inhibiting the interaction between KRS and 67LR can prevent and treat cancer by inhibiting cancer cell metastasis. Accordingly, the composition of the present invention can inhibit cancer metastasis, and thus provide a novel means for prevention and treatment of cancer.
Abstract:
A multi-view video encoding/decoding apparatus and method are provided. The multi-view video encoding/decoding apparatus encodes the current block which is to be encoded and which belongs to a frame of a first view point, wherein the encoding is performed in accordance with a first skip mode using the frame of the first view point or a second skip mode using the frame of a second view point, thereby improving encoding efficiency.
Abstract:
A method and apparatus for an adaptive Hypertext Transfer Protocol (HTTP) streaming service using metadata of content are provided. The metadata may include a minBufferTime attribute indicating a minimum amount of initially buffered media content. A terminal may receive content from a server before playback of the content, and may buffer the content by at least the minimum amount. The metadata may include a range attribute that designates a range of a target indicated by a Uniform Resource Locator (URL). The terminal may receive bytes designated by the range attribute from the URL, and may play back the content using the received bytes.
Abstract:
Disclosed is a positive photosensitive resin composition that includes (A) an alkali soluble resin selected from a polybenzoxazole precursor, a polyimide precursor, and a combination thereof, (B) a photosensitive diazoquinone compound, (C) a phenol compound, (D) an organic dye and (E) a solvent, wherein the organic dye (D) includes at least one red dye having an absorption wavelength of 590 to 700 nm, at least one yellow dye having an absorption wavelength of 550 to 590 nm, and at least one blue dye having an absorption wavelength of 450 to 500 nm.
Abstract:
Disclosed is a positive photosensitive resin composition that includes (A) an alkali soluble resin prepared by a phosphorous-containing diamine represented by the following Chemical Formula 1, (B) a photosensitive diazoquinone compound, and (C) a solvent. A photosensitive resin film prepared using the same and a semiconductor device including the photosensitive resin film are also disclosed. In Chemical Formula 1, each substituent is the same as defined in the detailed description.
Abstract:
The present invention provides haptic steering wheel switch apparatus including: a haptic wheel housing unit disposed on a steering wheel of a vehicle; a circuit board unit disposed in the haptic wheel housing unit; and a haptic wheel device unit including a haptic wheel device actuator establishing an electrical connection with the circuit board unit and including a haptic shaft, a haptic knob connected to the haptic shaft and exposedly disposed on one surface of the haptic wheel housing unit, and a haptic wheel device sensing unit for detecting a rotating state of the haptic shaft, wherein the haptic knob achieves a rotary operation on a plane formed by the steering wheel of the vehicle, the haptic wheel device actuator moves in a longitudinal direction of the haptic shaft, and a button switch unit operating vertically and independently of the haptic knob is provided outside the haptic knob.
Abstract:
A method and apparatus for an adaptive Hypertext Transfer Protocol (HTTP) streaming service using metadata of media content are provided. The media content may include a sequence of one or more periods. The metadata may include a start time attribute and/or a duration attribute of each of the periods. The metadata may determine a start time of each of the periods, and a start time of each of segments included in each of the periods. A terminal may access segments included in each of the periods, may decode and render data of media content included in the segments, and may play back the media content.
Abstract:
Disclosed herein is a. skin external composition containing ginseng berry extract. More specifically, disclosed is a skin external composition, which contains, as an active ingredient, ginseng berry extract having the specific components and compositions, among the above-ground parts of ginseng, and thus promotes the production of collagen in the skin, shows an MMP-I inhibitory effect and, at the same time, has skin-aging inhibitory and wrinkle-reducing effects, resulting from antioxidant effects and DNA damage-protecting effects. Also disclosed is a skin external composition, which contains, as an active ingredient, ginseng berry extract, which has a skin whitening effect resulting from the effects of inhibiting melanin production and reducing pigmentation caused by UV radiation, the effects of relieving dry skin symptoms and atopic symptoms by inducing and maintaining the normal differentiation of skin keratinocytes, the effect of relieving acne and skin troubles by the regulation of sebum secretion and an anti-inflammatory effect, and makes complexion ruddy through the improvement of peripheral blood circulation to make the skin clean and clear. Also disclosed is a food composition for reducing and preventing obesity, which contains, as an active ingredient, ginseng berry extract, which increases the expression of a carnitine palmitoyl transterase-1 (CPT-I) gene, serves to transport fatty acids into mitochondria in fatty acid oxidation and promotes fat oxidation.