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    Systems and methods for determining white matter fiber tractography
    42.
    发明授权
    Systems and methods for determining white matter fiber tractography 有权
    用于确定白质纤维束图的系统和方法

    公开(公告)号：US09478026B2

    公开(公告)日：2016-10-25

    申请号：US14673991

    申请日：2015-03-31

    Applicant: MUSC Foundation for Research Development ,  Golbarg Tarighat Saber

    Inventor： Jens Jensen ,  Ali Tabesh ,  Joseph Helpern

    IPC: G06T7/00 ,  A61B5/00 ,  A61B5/16 ,  A61B5/055 ,  G01R33/563

    CPC classification number: G06T7/0012 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/168 ,  A61B5/4088 ,  A61B5/4094 ,  A61B2576/026 ,  G01R33/56341 ,  G06T7/11 ,  G06T2207/10092 ,  G06T2207/30016

    Abstract: One aspect of the present disclosure relates to a system that can determine a kurtosis diffusion orientation distribution function (dODF) that can, for example, be used with diffusional kurtosis imaging fiber tractography (DKI-FT). The system can include a non-transitory memory storing computer-executable instructions and a processor that executes the computer-executable instructions to perform the following operations. Diffusion magnetic resonance imaging (dMRI) data can be received. Based on the dMRI data, a diffusion tensor (DT) and a diffusional kurtosis tensor (DKT) can be determined. A kurtosis dODF can be determined for the dMRI data based on the DT and the DKT. The kurtosis dODF extends a Gaussian approximation of the DT to include non-Gaussian corrections of the DKT.

    Abstract translation: 本公开的一个方面涉及一种可以确定峰值扩散取向分布函数（dODF）的系统，其可以例如与扩散峭度成像纤维束图（DKI-FT）一起使用。 该系统可以包括存储计算机可执行指令的非暂存存储器和执行计算机可执行指令以执行以下操作的处理器。 可以接收扩散磁共振成像（dMRI）数据。 基于dMRI数据，可以确定扩散张量（DT）和弥散张度张量（DKT）。 可以基于DT和DKT来确定dMRI数据的峰度dODF。 峰度dODF扩展了DT的高斯近似，以包括DKT的非高斯校正。

    SYSTEMS AND METHODS FOR DETERMINING WHITE MATTER FIBER TRACTOGRAPHY
    46.
    发明申请
    SYSTEMS AND METHODS FOR DETERMINING WHITE MATTER FIBER TRACTOGRAPHY 有权
    用于确定白色光纤TRACTOGRAPHY的系统和方法

    公开(公告)号：US20150279029A1

    公开(公告)日：2015-10-01

    申请号：US14673991

    申请日：2015-03-31

    Applicant: MUSC Foundation for Research Development

    Inventor： Jens Jensen ,  Ali Tabesh ,  Joseph Helpern

    IPC: G06T7/00 ,  A61B5/00 ,  A61B5/16 ,  A61B5/055

    CPC classification number: G06T7/0012 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/168 ,  A61B5/4088 ,  A61B5/4094 ,  A61B2576/026 ,  G01R33/56341 ,  G06T7/11 ,  G06T2207/10092 ,  G06T2207/30016

    Abstract: One aspect of the present disclosure relates to a system that can determine a kurtosis diffusion orientation distribution function (dODF) that can, for example, be used with diffusional kurtosis imaging fiber tractography (DKI-FT). The system can include a non-transitory memory storing computer-executable instructions and a processor that executes the computer-executable instructions to perform the following operations. Diffusion magnetic resonance imaging (dMRI) data can be received. Based on the dMRI data, a diffusion tensor (DT) and a diffusional kurtosis tensor (DKT) can be determined. A kurtosis dODF can be determined for the dMRI data based on the DT and the DKT. The kurtosis dODF extends a Gaussian approximation of the DT to include non-Gaussian corrections of the DKT.

    Abstract translation: 本公开的一个方面涉及一种可以确定峰值扩散取向分布函数（dODF）的系统，其可以例如与扩散峭度成像纤维束图（DKI-FT）一起使用。 该系统可以包括存储计算机可执行指令的非暂存存储器和执行计算机可执行指令以执行以下操作的处理器。 可以接收扩散磁共振成像（dMRI）数据。 基于dMRI数据，可以确定扩散张量（DT）和弥散张度张量（DKT）。 可以基于DT和DKT来确定dMRI数据的峰度dODF。 峰度dODF扩展了DT的高斯近似，以包括DKT的非高斯校正。

    Expandable vertebral body replacement device and method
    50.
    发明授权
    Expandable vertebral body replacement device and method 有权

    公开(公告)号：US12295858B2

    公开(公告)日：2025-05-13

    申请号：US17821995

    申请日：2022-08-24

    Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT

    Inventor： Mark Evald Semler ,  Bruce Frankel ,  Joseph Ruscito

    IPC: A61F2/44 ,  A61F2/30

    Abstract: An expandable vertebral body implant, and methods of assembly and using the implant. The vertebral body implant includes a body with a first end and a second end, a rotating member rotatably coupled to the first end of the body, wherein an end includes a plurality of first notches inset into the rotating member, an extension member moveably coupled to the rotating member, and a locking member positioned on an interior of the body. Methods for assembling and using the vertebral body implant are also disclosed.

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