公开(公告)号：US20190170734A1

公开(公告)日：2019-06-06

申请号：US16172465

申请日：2018-10-26

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Ji Qi

IPC: G01N33/52 ,  G01N33/53 ,  G01N15/14 ,  G01N21/64 ,  B01L3/00

Abstract: Among other things, the present invention is related to devices and methods for imaging a liquid sample between two plates.

公开(公告)号：US12270810B2

公开(公告)日：2025-04-08

申请号：US16484035

申请日：2018-02-09

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Yufan Zhang ,  Ji Qi

IPC: G01N33/543 ,  B01L3/00 ,  G01N1/31 ,  G01N33/49

Abstract: The present invention provides QMAX based devices, kits, and methods for rapid, easy to use, and/or inexpensive detection of assaying.

公开(公告)号：US20250076293A1

公开(公告)日：2025-03-06

申请号：US18954475

申请日：2024-11-20

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Yufan Zhang ,  Ji Li ,  Ji Qi ,  Jun Tian

IPC: G01N33/543 ,  G06T7/00

Abstract: Among other things, the present invention is related to devices and methods of performing biological and chemical assays, such as but not limited to immunoassays and nucleic assay acid, particularly the homogeneous assay that does not use the step of wash and that is fast (e.g. 60 seconds from dropping a sample to displaying results).

公开(公告)号：US12226769B2

公开(公告)日：2025-02-18

申请号：US18121534

申请日：2023-03-14

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Ji Qi ,  Hua Tan ,  Yufan Zhang

IPC: B01L3/00 ,  B01L7/00 ,  C12Q1/686

Abstract: The disclosure relates to a device and method of using the device for performing biological and chemical assays that require an easy sample manipulation and/or a rapid change or a rapid thermal cycling of a sample temperature (e.g., Polymerase Chain Reaction (PCR) for amplifying nucleic acids). The device includes a first plate, a second plate, a plurality of spacers, and at least one clamp. The method includes obtaining the device, depositing a sample onto a sample contact area of at least one of the first and second plates of the device in an open configuration, closing the two plates into a closed configuration and placing the clamp in the active mode, and rapidly changing the temperature of the sample portion encircled by rings.

公开(公告)号：US12169167B2

公开(公告)日：2024-12-17

申请号：US17422444

申请日：2020-02-19

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Ji Li ,  Shengjian Cai ,  Yu Sun

IPC: G01N31/00 ,  G01N1/31 ,  G01N33/53 ,  G01N33/543 ,  G01N33/569

Abstract: Disclosed are devices, kits, apparatus, and methods for rapid homogenous cell staining and imaging.

公开(公告)号：US20240241075A1

公开(公告)日：2024-07-18

申请号：US18434795

申请日：2024-02-06

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Yufan Zhang

IPC: G01N27/403 ,  B01L3/00 ,  G01N1/28 ,  G01N1/38 ,  G01N21/84 ,  G01N33/49 ,  G01N33/543 ,  G01N35/00

CPC classification number: G01N27/403 ,  B01L3/502761 ,  G01N1/2813 ,  G01N1/286 ,  G01N1/38 ,  G01N21/8483 ,  G01N33/4905 ,  G01N33/5438 ,  G01N35/00 ,  B01L2200/0668 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2400/0415

Abstract: Described are methods and devices that can accelerate the process and quantify the parameters for bio/chemical material samples. In some embodiments, a QMAX (Q: quantification; M: magnifying; A: adding reagents; X: acceleration) device having two or more electrodes capable of accelerating the electrical measurement process of the samples. In addition, the electrical measurement technology of the QMAX device enables for extraction, separation, and purification of sample components, such as but not limited to nucleic acids. In some embodiments, the QMAX device includes a plate for hosting a small sensing chip to facilitate a bio/chemical sensing of the sensing chip.

公开(公告)号：US11927533B2

公开(公告)日：2024-03-12

申请号：US17985654

申请日：2022-11-11

Applicant: Essenlix Corporation

Inventor： Ji Qi ,  Stephen Y. Chou ,  Wei Ding

IPC: G01N21/64

CPC classification number: G01N21/6428 ,  G01N21/6458 ,  G01N2021/6439 ,  G01N2201/021 ,  G01N2201/0634 ,  G01N2201/0636

Abstract: A multi-mode illumination system, including: a first illumination module; a second illumination module; and a third illumination module, as disclosed herein.

公开(公告)号：US11883824B2

公开(公告)日：2024-01-30

申请号：US16081970

申请日：2018-02-09

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Ji Qi ,  Yufan Zhang

IPC: B01L3/00 ,  G01N21/84 ,  G01N33/543 ,  G01N21/03

CPC classification number: B01L3/50853 ,  B01L3/5088 ,  G01N21/03 ,  G01N21/84 ,  G01N33/543 ,  G01N33/54366 ,  B01L2300/04 ,  B01L2300/0609 ,  B01L2300/0829 ,  B01L2300/0851 ,  B01L2300/0861

Abstract: Disclosure relates to a device and a method of using the device for conducting biological and chemical assays on a sample. The device includes two plates. The first plate includes at least a first and a second sample contact areas on its inner surface. Each sample contact area includes spacers having a bottom end fixed on the inner surface and a top end that is distal to the inner surface. The spacers in the first sample contact area differ in height from those in the second sample contact area. The first and second sample contact areas are disposed at different depths along the inner surface of the first plate, so that the top ends of the spacers are aligned on the same flat plane. The method includes depositing the sample onto the sample contact areas, compressing the sample into a thin layer, and analyzing the sample.

公开(公告)号：US11761861B2

公开(公告)日：2023-09-19

申请号：US17487922

申请日：2021-09-28

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Ji Qi

IPC: G01N1/28 ,  G01N1/31 ,  G01N33/49 ,  G02B17/00 ,  G06V10/143 ,  G06V20/69 ,  G01N15/00

CPC classification number: G01N1/2813 ,  G01N1/312 ,  G01N33/49 ,  G01N33/492 ,  G02B17/006 ,  G06V10/143 ,  G06V20/695 ,  B01L2300/0816 ,  G01N2015/008 ,  G01N2015/0073 ,  G01N2015/0084

Abstract: Disclosed are devices and methods for analyzing an analyte, such as white blood cells in liquid samples.

公开(公告)号：US11733500B2

公开(公告)日：2023-08-22

申请号：US17266475

申请日：2019-08-16

Applicant: Essenlix Corporation

Inventor： Stephen Y. Chou ,  Wei Ding ,  Wu Chou ,  Ji Qi ,  Jun Tian ,  Yuecheng Zhang ,  Mingquan Wu

IPC: H04N23/51 ,  H04N23/55 ,  G02B21/00 ,  G06T7/90 ,  G06N20/00 ,  G01J3/52

CPC classification number: G02B21/0008 ,  G01J3/524 ,  G02B21/0032 ,  G06N20/00 ,  G06T7/90 ,  H04N23/51 ,  H04N23/55

Abstract: Disclosed is an apparatus and method for imaging: a side-view of a object on a surface, a Contact Angle of a liquid object, the color of an object, or combinations thereof.