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公开(公告)号:US06884995B2
公开(公告)日:2005-04-26
申请号:US10610677
申请日:2003-07-02
CPC分类号: H01J49/005 , H01J49/062
摘要: A mass spectrometer is disclosed comprising a collision cell wherein ions having substantially different mass to charge ratios are arranged to be transmitted through at least a portion of the collision cell at substantially the same time and with substantially the same velocity preferably by means of one or more transient DC voltages or one or more transient DC voltage waveforms which are applied to the electrodes forming the collision cell so that ions are urged through the collision cell at a constant controlled velocity. By appropriate setting of the velocity of the DC voltage or DC voltage waveform passing along the length of the collision cell an efficient collision cell is provided which is able to fragment ions having considerably different mass to charge ratio at substantially the same time in an optimal manner.
摘要翻译: 公开了一种质谱仪,其包括碰撞池,其中具有基本上不同的质荷比的离子被布置成在基本相同的时间和基本上相同的速度下通过至少一部分的碰撞池传播通过一个或多个 瞬态DC电压或一个或多个瞬态DC电压波形,其被施加到形成碰撞电池的电极,使得离子以恒定的受控速度被迫穿过碰撞池。 通过适当设定沿着碰撞电池的长度通过的直流电压或直流电压波形的速度,提供了一种有效的碰撞电池,其能够以最佳方式在基本上相同的时间将具有相当不同质荷比的离子分解 。
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公开(公告)号:US06882411B2
公开(公告)日:2005-04-19
申请号:US10371712
申请日:2003-02-21
IPC分类号: G01N21/958 , G01M11/00 , G01M11/02 , G01B9/00
CPC分类号: G01M11/0278 , G01M11/0214
摘要: The invention includes methods and apparatuses for inspecting optical devices, particularly contact lenses.
摘要翻译: 本发明包括用于检查光学装置,特别是隐形眼镜的方法和装置。
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公开(公告)号:US06642514B2
公开(公告)日:2003-11-04
申请号:US09930227
申请日:2001-08-16
申请人: Robert Harold Bateman , Kevin Giles
发明人: Robert Harold Bateman , Kevin Giles
IPC分类号: B01D5944
CPC分类号: H01J49/065
摘要: A mass spectrometer is disclosed comprising an ion guide which spans two or more vacuum chambers. The ion guide comprises a plurality of electrodes having apertures. Preferably, one of the electrodes also forms a differential pumping aperture which separates two vacuum chambers.
摘要翻译: 公开了一种质谱仪,其包括跨越两个或更多个真空室的离子导向器。 离子导向器包括具有孔的多个电极。 优选地,电极中的一个还形成分离两个真空室的差分泵浦孔。
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公开(公告)号:US09111654B2
公开(公告)日:2015-08-18
申请号:US14003487
申请日:2012-03-07
申请人: Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
发明人: Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
CPC分类号: G21K1/00 , H01J49/062 , H01J49/28 , H01J49/427
摘要: An ion guide is disclosed comprising a plurality of electrodes. A first device is arranged and adapted to apply a RF voltage to at least some of the electrodes in order to form, in use, a pseudo-potential well which acts to confine ions in a first direction within the ion guide. A second device is arranged and adapted to apply a DC voltage to at least some of the electrodes in order to form, in use, a DC potential well which acts to confine ions in a second direction within the ion guide. A third device is arranged and adapted to cause ions having desired or undesired mass to charge ratios to be mass to charge ratio selectively ejected from the ion guide in the second direction.
摘要翻译: 公开了一种离子导向器,其包括多个电极。 第一装置被布置并适于将RF电压施加到至少一些电极,以在使用中形成用于将离子限制在离子导向器内的第一方向上的伪电位阱。 第二装置被布置并适于将DC电压施加到至少一些电极,以在使用中形成用于在离子导向器内沿第二方向限制离子的DC势阱。 第三装置被布置并适于使具有期望或不需要的质量的充电比例的离子成为从第二方向从离子导向器选择性地喷射的质荷比。
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公开(公告)号:US20140299761A1
公开(公告)日:2014-10-09
申请号:US14240667
申请日:2012-08-22
申请人: Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
发明人: Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
IPC分类号: H01J49/42
CPC分类号: H01J49/424 , H01J49/421 , H01J49/422 , H01J49/4285
摘要: A mass or mass to charge ratio selective ion trap is disclosed having an increased charge storage capacity. A RF voltage acts to confine ions in a first (y) direction within the ion trap. A DC voltage and/or an RF voltage acts to confine ions in a second (x) direction within the ion trap. A quadratic DC potential well acts to confine ions in a third (z) direction within the ion trap. Ions are excited in the third (z) direction and are caused to be mass or mass to charge ratio selectively ejected in the third (z) direction.
摘要翻译: 公开了具有增加的电荷存储容量的质量或质量 - 电荷比选择性离子阱。 RF电压用于将离子限制在离子阱内的第一(y)方向。 DC电压和/或RF电压用于将离子限制在离子阱内的第二(x)方向。 二次直流势阱用于将离子限制在离子阱内的第三(z)方向。 离子在第三(z)方向上被激发,并且被导致在第三(z)方向上选择性地喷射的质量或质量 - 充电比。
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公开(公告)号:US20140291501A1
公开(公告)日:2014-10-02
申请号:US14130440
申请日:2012-07-06
CPC分类号: H01J49/0059 , G01N27/624 , H01J49/0027 , H01J49/0031 , H01J49/062 , H01J49/10 , H01J49/26 , H01J49/40 , H01J49/422 , H01J49/4245
摘要: A method of mass spectrometry is disclosed comprising directing first photons from a laser onto ions located within a 2D or linear ion guide or ion trap. The frequency of the first photons is scanned and first photons and/or second photons emitted by the ions are detected. The ions are then mass analysed using a Time of Flight mass analyser.
摘要翻译: 公开了一种质谱方法,其包括将来自激光器的第一光子引导到位于2D或线性离子导向器或离子阱内的离子上。 扫描第一光子的频率,并检测由离子发射的第一光子和/或第二光子。 然后使用飞行时间质量分析仪对离子进行质量分析。
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公开(公告)号:US20140048696A1
公开(公告)日:2014-02-20
申请号:US14003487
申请日:2012-03-07
申请人: Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
发明人: Kevin Giles , Martin Raymond Green , Daniel James Kenny , David J. Langridge , Jason Lee Wildgoose
CPC分类号: G21K1/00 , H01J49/062 , H01J49/28 , H01J49/427
摘要: An ion guide is disclosed comprising a plurality of electrodes. A first device is arranged and adapted to apply a RF voltage to at least some of the electrodes in order to form, in use, a pseudo-potential well which acts to confine ions in a first direction within the ion guide. A second device is arranged and adapted to apply a DC voltage to at least some of the electrodes in order to form, in use, a DC potential well which acts to confine ions in a second direction within the ion guide. A third device is arranged and adapted to cause ions having desired or undesired mass to charge ratios to be mass to charge ratio selectively ejected from the ion guide in the second direction.
摘要翻译: 公开了一种离子导向器,其包括多个电极。 第一装置被布置并适于将RF电压施加到至少一些电极,以在使用中形成用于将离子限制在离子导向器内的第一方向上的伪电位阱。 第二装置被布置并适于将DC电压施加到至少一些电极,以在使用中形成用于在离子导向器内沿第二方向限制离子的DC势阱。 第三装置被布置并适于使具有期望或不需要的质量的充电比例的离子成为从第二方向从离子导向器选择性地喷射的质荷比。
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48.
公开(公告)号:US20140048695A1
公开(公告)日:2014-02-20
申请号:US14001078
申请日:2012-02-24
申请人: Kevin Giles , Martin Raymond Green , Daniel James Kenny , Jason Lee Wildgoose , David. J. Langridge
发明人: Kevin Giles , Martin Raymond Green , Daniel James Kenny , Jason Lee Wildgoose , David. J. Langridge
CPC分类号: H01J49/063 , H01J49/065 , H01J49/26 , H01J49/42
摘要: A non-linear ion guide is disclosed comprising a plurality of electrodes. An ion guiding region is arranged between the electrodes, and the ion guiding region curves at least in a first direction. A DC voltage is applied to at least some of the electrodes in order to form a DC potential well which acts to confine ions within the ion guiding region in the first direction.
摘要翻译: 公开了一种包括多个电极的非线性离子导向器。 离子引导区域布置在电极之间,并且离子引导区域至少沿第一方向弯曲。 DC电压被施加到至少一些电极,以便形成用于将离子限制在第一方向上的离子引导区域内的DC势阱。
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公开(公告)号:US08581181B2
公开(公告)日:2013-11-12
申请号:US12679139
申请日:2008-09-22
申请人: Kevin Giles
发明人: Kevin Giles
IPC分类号: H01J49/00
CPC分类号: H01J49/065 , H01J49/062 , H01J49/26
摘要: An ion guiding device is disclosed comprising a first ion guide which is conjoined with a second ion guide. Ions are urged across a radial pseudo-potential barrier which separates the two guiding regions by a DC potential gradient. Ions may be transferred from an ion guide which has a relatively large cross-sectional profile to an ion guide which has a relatively small cross-sectional profile in order to improve the subsequent ion confinement of the ions.
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公开(公告)号:US08471200B2
公开(公告)日:2013-06-25
申请号:US12528203
申请日:2008-02-25
申请人: Iain Campuzano , Kevin Giles , Chris Hughes
发明人: Iain Campuzano , Kevin Giles , Chris Hughes
IPC分类号: H01J49/04
CPC分类号: H01J49/0481 , H01J49/0431 , H01J49/067
摘要: A mass spectrometer is disclosed comprising a sampling cone and a cone-gas cone wherein, in use, sulphur hexa fluoride (‘SF6’) is supplied as a cone gas to the annulus between the cone-gas cone and the sampling cone in order to improve the transmission of high molecular mass ions passing through the sampling cone into and through subsequent stages of the mass spectrometer.
摘要翻译: 公开了一种质谱仪,其包括采样锥体和锥形气体锥体,其中在使用中将六氟化硫(“SF 6”)作为锥形气体供应到锥形气体锥体和采样锥体之间的环形空间,以便 改善通过采样锥体的高分子质子离子进入质谱仪后续阶段的传播。
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