利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

101 条记录 (耗时 0.029 秒)

    MICROFABRICATED APPARATUS FOR CELL BASED ASSAYS
    42.
    发明申请
    MICROFABRICATED APPARATUS FOR CELL BASED ASSAYS 有权
    用于细胞测定的微晶装置

    公开(公告)号：US20090239292A1

    公开(公告)日：2009-09-24

    申请号：US12236120

    申请日：2008-09-23

    申请人： Nicholas Thomas ,  Per Andersson

    发明人： Nicholas Thomas ,  Per Andersson

    IPC分类号： C12M1/12 ,  C12M1/22

    CPC分类号： B01L3/5027 ,  B01L3/502707 ,  B01L3/502753 ,  B01L3/502761 ,  B01L2200/10 ,  B01L2300/0806 ,  B01L2300/0864 ,  B01L2300/087 ,  B01L2300/0877 ,  B01L2300/10 ,  B01L2400/0409 ,  B01L2400/0688 ,  C12M23/16 ,  C12M23/38 ,  C12M25/16

    摘要： Apparatus and methods are provided for performing cell growth and cell based assays in a liquid medium. The apparatus comprises a base plate supporting a plurality of micro-channel elements, each micro-channel element comprising a cell growth chamber, an inlet channel and an outlet channel, a cover plate positioned over the base plate to define the chambers and connecting channels. Means are incorporated in the cell growth chambers, for cell attachment and cell growth. In particular, the invention provides a rotatable disc microfabricated for performing cell growth and cell based assays. The apparatus and method can be used for the growth of cells and the detection and measurement of variety of biochemical processes and products using non-invasive techniques, that is techniques which do not compromise the integrity or viability of cells.

    摘要翻译： 提供了用于在液体培养基中进行细胞生长和基于细胞的测定的装置和方法。 该装置包括支撑多个微通道元件的基板，每个微通道元件包括细胞生长室，入口通道和出口通道，位于基板上方以限定室和连接通道的盖板。 手段被并入细胞生长室，用于细胞附着和细胞生长。 特别地，本发明提供了一种用于进行细胞生长和基于细胞的测定法的可旋转圆盘。 该装置和方法可用于细胞的生长以及使用非侵入性技术检测和测量各种生化过程和产物，即不损害细胞完整性或活力的技术。

    Maintaning a View of a Cluster's Membership
    43.
    发明申请
    Maintaning a View of a Cluster's Membership 审中-公开
    维护集群成员的视图

    公开(公告)号：US20080201403A1

    公开(公告)日：2008-08-21

    申请号：US11576235

    申请日：2004-09-29

    申请人： Per Andersson ,  Maria Toeroe ,  Makan Pourzandi ,  Frederic Rossi ,  Andre Beliveau

    发明人： Per Andersson ,  Maria Toeroe ,  Makan Pourzandi ,  Frederic Rossi ,  Andre Beliveau

    IPC分类号： G06F15/16

    CPC分类号： H04L45/04 ,  H04L45/02 ,  H04L45/025 ,  H04L45/46 ,  H04W4/08 ,  H04W8/186

    摘要： A method for maintaining a current view of a cluster's membership comprising the steps of maintaining a list of member nodes and updating the list when a modification thereto is noticed by a first node by receiving a first update message from the first node in a second node, thereafter, sending a second update message from the second node to a third node to propagate the modification and sending to the first node a first confirm message from the second or the third node. A node member of a cluster capable of maintaining a first list of neighboring nodes, maintaining a second list of neighboring nodes sharing a current view therewith and ensuring that the first list matches the second by exchanging messages with neighboring nodes, wherein each message comprises topology information. Upon confirmation that both lists match, the node being capable of sending a confirmation message toward neighboring nodes.

    摘要翻译： 一种用于维护群集成员的当前视图的方法，包括以下步骤：通过从第一节点的第一节点接收第一更新消息，维护成员节点的列表，并且当第一节点对其进行修改时，更新列表， 此后，将第二更新消息从第二节点发送到第三节点，以传播修改，并向第一节点发送来自第二节点或第三节点的第一确认消息。 能够维护相邻节点的第一列表的集群的节点成员，维护与其共享当前视图的相邻节点的第二列表，并且通过与相邻节点交换消息来确保第一列表与第二列表匹配，其中每个消息包括拓扑信息 。 在确认两个列表匹配时，节点能够向邻近节点发送确认消息。

    Installing A New View Of A Cluster Membership
    44.
    发明申请
    Installing A New View Of A Cluster Membership 审中-公开
    安装集群成员资格的新视图

    公开(公告)号：US20070291772A1

    公开(公告)日：2007-12-20

    申请号：US11576260

    申请日：2004-09-29

    申请人： Per Andersson ,  Maria Toeroe ,  Makan Pourzandi ,  Frederic Rossi ,  Andre Beliveau

    发明人： Per Andersson ,  Maria Toeroe ,  Makan Pourzandi ,  Frederic Rossi ,  Andre Beliveau

    IPC分类号： H04L12/56

    CPC分类号： H04L41/0893 ,  H04L45/46 ,  H04W4/08

    摘要： A node member of a cluster in a network comprising a plurality of nodes and a method related to the capabilities of the node, which is capable of maintaining a stable view of the cluster's membership, maintaining a list of neighboring nodes sharing a same updated view of the cluster's membership and receiving a confirmation message from a second node confirming that a new view received therein should replace the stable view and become a new stable view. The node is further capable of verifying that the new view is up to date in comparison to the same view and, if the new view is not up to date, discarding the confirmation message.

    摘要翻译： 包括多个节点的网络中的集群的节点成员和与所述节点的能力相关的方法，所述方法能够维护所述集群的成员资格的稳定视图，维护共享相同更新视图的相邻节点的列表 群集的成员资格并从第二节点接收确认消息，确认其中收到的新视图应该替代稳定视图并成为新的稳定视图。 该节点还能够验证新视图与同一视图相比是最新的，并且如果新视图不是最新的，则丢弃该确认消息。

    Configurable distribution of signals in a network
    45.
    发明申请
    Configurable distribution of signals in a network 审中-公开
    网络中可配置的信号分配

    公开(公告)号：US20060179013A1

    公开(公告)日：2006-08-10

    申请号：US11261483

    申请日：2005-10-31

    申请人： Andre Beliveau ,  Per Andersson

    发明人： Andre Beliveau ,  Per Andersson

    IPC分类号： G06G7/00 ,  G06F15/18

    CPC分类号： H04L67/1008 ,  H04L67/1002 ,  H04L67/1017 ,  H04L67/327 ,  H04W24/02

    摘要： A method and a distributor are provided for ensuring efficient and expandable distribution of signals in a network. Distribution rules are defined by configuration in a distributor. A rule comprises one or more patterns used to attempt finding a match with a signal content. A result of a match attempt in a rule may lead to a destination for the signal content or to another rule. Rules are assembled hierarchically to form a decision tree. A network of distributors may be used instead of a single distributor. Functional units use distributors to exchange signals content. A configuration of the decision tree can be modified without impacting ongoing signal distribution. Functional units can be added, split or otherwise reorganized without having to cater for signal distribution modifications.

    摘要翻译： 提供了一种方法和分配器，用于确保网络中信号的有效和可扩展分布。 分销规则由分销商中的配置定义。 规则包括用于尝试找到与信号内容匹配的一个或多个模式。 规则中的匹配尝试的结果可能导致信号内容的目的地或另一规则。 规则分层组合以形成决策树。 可以使用分销商网络而不是单个分销商。 功能单元使用分销商交换信号内容。 可以修改决策树的配置，而不影响正在进行的信号分配。 功能单位可以添加，拆分或以其他方式重新组织，而无需适应信号分配修改。

    Integrated microfluidic device (ea)
    47.
    发明申请
    Integrated microfluidic device (ea) 审中-公开
    集成微流体装置（ea）

    公开(公告)号：US20050277195A1

    公开(公告)日：2005-12-15

    申请号：US10513084

    申请日：2003-04-29

    申请人： Mats Holmquist ,  Johan Engstrom ,  Anders Palm ,  Per Andersson ,  Gunnar Ekstrand

    发明人： Mats Holmquist ,  Johan Engstrom ,  Anders Palm ,  Per Andersson ,  Gunnar Ekstrand

    IPC分类号： B01L3/00 ,  G01N31/10

    CPC分类号： B01L3/5027 ,  B01J2219/00536 ,  B01J2219/00725 ,  B01J2219/00738 ,  B01L2200/0605 ,  B01L2300/0806 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0633 ,  B01L2400/0688

    摘要： A method for characterizing n components An of n catalytic systems. The method is characterized in comprising the steps of: I) providing a microfluidic device which comprises a plurality of identical microchannel structures, each microchannel structures comprising in the downstream direction (a) an inlet arrangement IA with at least one inlet port; (b) a catalytic microcavity MC1, which comprises an immobilized component Cim of the catalytic system CS used in the microchannel structure, and (c) a detection zone (DZ); ii) distributing to MC1 of each microchannel structure the remaining components of the CS used in the structure by a) dispensing to the inlet arrangement IA of each microchannel structure said remaining components; and b) transporting corresponding components for the microchannel structures in parallel to load MC1 in each microchannel structure; iii) performing the catalytic reaction in MC1 of each microchannel structure; iv) transporting in parallel the product formed in step (iii) from MC1 to DZ of each microchannel structure, if DZ and MC1 do not coincide; v) characterizing for each microchannel structure the result of the catalytic reaction performed in MC1 in DZ; and vi) characterizing An for each microchannel structure.

    摘要翻译： 一种用于表征n种催化体系的n组分的方法。 该方法的特征在于包括以下步骤：I）提供微流体装置，其包括多个相同的微通道结构，每个微通道结构在下游方向（a）包括具有至少一个入口的入口装置1A; （b）催化微腔MC1，其包含在微通道结构中使用的催化体系CS的固定组分C 1和（c）检测区（DZ）; ii）通过以下方式向每个微通道结构的MC1分配用于结构中的CS的剩余部件：a）将每个微通道结构的入口装置1A分配给所述剩余部件; 和b）将微通道结构的相应部件平行运送到每个微通道结构中的负载MC1; iii）在每个微通道结构的MC1中进行催化反应; iv）如果DZ和MC1不重合，则将步骤（iii）中形成的产品从MC1至DZ平行运输; v）表征每个微通道结构在DZ中在MC1中进行的催化反应的结果; 和vi）表征每个微通道结构的An。