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公开(公告)号：US20130029324A1
公开(公告)日：2013-01-31
申请号：US13519270
申请日：2010-12-30
CPC分类号： C12Q1/04 , B01L3/502 , B01L3/5029 , B01L3/5082 , B01L2300/042 , B01L2300/046 , B01L2300/0672 , B01L2300/087 , B01L2400/0478 , B01L2400/0644 , B01L2400/0683 , G01N33/5005
摘要： The present invention provides methods to concentrate cells onto microparticles, to concentrate the microparticles, and to detect the cells. The present invention also includes unitary sample preparation and detection devices to be used in accordance with the methods.
摘要翻译： 本发明提供了将细胞浓缩到微粒上，浓缩微粒并检测细胞的方法。 本发明还包括根据该方法使用的单一样品制备和检测装置。
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42.发明申请COATED SUBSTRATES COMPRISING A CELL EXTRACTANT AND BIODETECTION METHODS THEREOF 审中-公开包含细胞提取物的包被基质和其生物测定方法公开(公告)号：US20120100531A1
公开(公告)日：2012-04-26
申请号：US13266493
申请日：2010-05-06
申请人： Raj Rajagopal , Smarajit Mitra , Matthew D. Reier
发明人： Raj Rajagopal , Smarajit Mitra , Matthew D. Reier
CPC分类号： C12Q1/04 , B01L3/5029 , B01L3/5082 , B01L2200/16 , B01L2300/0672 , B01L2400/0683 , C12M23/08 , C12M23/32 , C12M23/34 , C12M33/02
摘要： Articles are provided for the detection of cells in a sample. The articles include a release element. The release element comprises a coated substrate that includes a cell extractant. The release element controls the release of the cell extractant into a liquid mixture containing the sample. Methods of use are also disclosed.
摘要翻译： 提供了用于检测样品中细胞的文章。 这些物品包括释放元件。 释放元件包括包含细胞提取剂的涂覆基质。 释放元件控制细胞提取物释放到含有样品的液体混合物中。 还公开了使用方法。
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公开(公告)号：US20110303657A1
公开(公告)日：2011-12-15
申请号：US13214808
申请日：2011-08-22
IPC分类号： H05B6/78
CPC分类号： G01N35/00069 , B01L3/5025 , B01L3/5027 , B01L3/50273 , B01L3/502738 , B01L7/52 , B01L2200/027 , B01L2300/0681 , B01L2300/0806 , B01L2300/0864 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2300/1822 , B01L2300/1861 , B01L2400/0409 , B01L2400/0661 , B01L2400/0677 , B03C1/30 , F27B9/16 , F27D5/00 , G01N35/0098 , H05B6/80 , Y10T436/2575
摘要： Devices, systems, and methods for processing sample materials. The sample materials may be located in a plurality of process chambers in the device, which is rotated during heating of the sample materials.
摘要翻译： 用于处理样品的设备，系统和方法。 样品材料可以位于装置中的多个处理室中，其在样品材料的加热期间旋转。
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公开(公告)号：US20100285520A1
公开(公告)日：2010-11-11
申请号：US12743245
申请日：2008-11-19
申请人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
发明人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , Matthew D. Reier , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati
CPC分类号： G01N1/38 , B01L3/5029
摘要： A system and method for preparing samples to test an environmental surface for an analyte of interest. The system can include a deformable self-supporting receptacle comprising a reservoir, and a loaded substrate positioned in the reservoir of the deformable self-supporting receptacle. The loaded substrate can include a substrate and a source collected from the surface. The method can include combining the loaded substrate and a diluent in the reservoir, and agitating the loaded substrate and the diluent to form a liquid composition comprising the source and the diluent.
摘要翻译： 用于制备样品以测试感兴趣分析物的环境表面的系统和方法。 该系统可以包括可变形的自支撑容器，其包括储存器和位于可变形自支撑容器的储存器中的加载基板。 装载的衬底可以包括衬底和从表面收集的源。 该方法可以包括将加载的基底和稀释剂组合在储存器中，并且搅拌加载的基底和稀释剂以形成包含源和稀释剂的液体组合物。
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公开(公告)号：US20100255484A1
公开(公告)日：2010-10-07
申请号：US12743252
申请日：2008-11-19
申请人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati , Daniel E. Siltberg , Paul J. Cobian , Theresa J. Gerten
发明人： Kurt J. Halverson , Stephen C.P. Joseph , Raj Rajagopal , David J. Velasquez , Cynthia D. Zook , Sailaja Chandrapati , Daniel E. Siltberg , Paul J. Cobian , Theresa J. Gerten
CPC分类号： G01N1/38 , G01N1/4077 , G01N2001/4088
摘要： A system and method for preparing and collecting samples for analyte testing. The system can include a sample preparation system and a sample collection system coupled to the sample preparation system. The sample preparation system can include at least one of a deformable self-supporting receptacle comprising a reservoir and a freestanding receptacle comprising a reservoir. The reservoir can be adapted to contain a liquid composition. The sample collection system can be positioned in fluid communication with a reservoir of the sample preparation system, and can be adapted to capture an analyte of interest. The method can include providing a fluid path defined at least partially by the sample preparation system and the sample collection system, positioning the liquid composition in a reservoir of the sample preparation system, and moving at least a portion of the liquid composition in the fluid path to the sample collection system.
摘要翻译： 用于制备和收集样品用于分析物测试的系统和方法。 该系统可以包括与样品制备系统耦合的样品制备系统和样品收集系统。 样品制备系统可以包括可变形的自支撑容器中的至少一个，其包括储存器和包括储存器的独立容器。 储存器可以适于容纳液体组合物。 样品收集系统可以定位成与样品制备系统的储存器流体连通，并且可以适于捕获感兴趣的分析物。 该方法可以包括提供至少部分地由样品制备系统和样品收集系统限定的流体路径，将液体组合物定位在样品制备系统的储存器中，并且将至少一部分液体组合物移动到流体路径 到采样系统。
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公开(公告)号：US20080314895A1
公开(公告)日：2008-12-25
申请号：US12205170
申请日：2008-09-05
IPC分类号： H05B6/78
CPC分类号： G01N35/00069 , B01L3/5025 , B01L3/5027 , B01L3/50273 , B01L3/502738 , B01L7/52 , B01L2200/027 , B01L2300/0681 , B01L2300/0806 , B01L2300/0864 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2300/1822 , B01L2300/1861 , B01L2400/0409 , B01L2400/0661 , B01L2400/0677 , B03C1/30 , F27B9/16 , F27D5/00 , G01N35/0098 , H05B6/80 , Y10T436/2575
摘要： Devices, systems, and methods for processing sample materials. The sample materials may be located in a plurality of process chambers in the device, which is rotated during heating of the sample materials.
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47.发明授权Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix 失效在疏水基质中使用亲水性固体载体从生物混合物中除去有机分子的方法和装置公开(公告)号：US07347976B2
公开(公告)日：2008-03-25
申请号：US10027226
申请日：2001-12-20
申请人： Ranjani V. Parthasarathy , Raj Rajagopal , Vicky L. Morris , William Bedingham , Barry W. Robole
发明人： Ranjani V. Parthasarathy , Raj Rajagopal , Vicky L. Morris , William Bedingham , Barry W. Robole
IPC分类号： B01L11/00
CPC分类号： C12N15/1006 , Y10T428/25 , Y10T436/25 , Y10T436/25125 , Y10T436/25375 , Y10T436/255
摘要： Methods and devices for removing small negatively charged molecules from a biological sample mixture that uses a solid-phase extraction material that includes a hydrophilic solid support at least partially embedded within a hydrophobic matrix.
摘要翻译： 用于从使用固相萃取材料的生物样品混合物中去除小负电荷分子的方法和装置，所述固相萃取材料包括至少部分嵌入疏水基质内的亲水性固体支持物。
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公开(公告)号：US06756225B2
公开(公告)日：2004-06-29
申请号：US09797343
申请日：2001-03-01
IPC分类号： C12M122
摘要： Thin film culture devices are described that have positioning structures, as well as methods for harvesting cells from colonies on the culture device based on location of colonies on the device relative to the positioning structures. In addition, a computer readable medium encoded with a computer program is described that identifies position of colonies relative to the positioning structures.
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