公开(公告)号：US20160256633A1

公开(公告)日：2016-09-08

申请号：US15156616

申请日：2016-05-17

Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH

Inventor： Robert Frederick Veasey ,  Robert Perkins ,  David Aubrey Plumptre

IPC: A61M5/315

CPC classification number: A61M5/24 ,  A61M5/31528 ,  A61M5/31533 ,  A61M5/31535 ,  A61M5/31536 ,  A61M5/31541 ,  A61M5/31546 ,  A61M5/31551 ,  A61M5/3156 ,  A61M5/31563 ,  A61M5/31565 ,  A61M5/31568 ,  A61M5/3157 ,  A61M5/31575 ,  A61M5/31578 ,  A61M5/31585 ,  A61M5/31593 ,  A61M5/32 ,  A61M2005/2407 ,  A61M2005/3126 ,  A61M2205/581 ,  A61M2205/582

Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

公开(公告)号：US20160243027A1

公开(公告)日：2016-08-25

申请号：US15027296

申请日：2014-10-02

Applicant: NDM TECHNOLOGIES LIMITED

Inventor： Dewan Fazlul Hoque Chowdhury

IPC: A61K9/00 ,  B29C39/02 ,  A61M5/32 ,  B29C43/36 ,  B29C41/02 ,  B29C43/02 ,  B29C47/00

CPC classification number: A61K9/0024 ,  A61K38/1709 ,  A61M5/32 ,  A61M37/0015 ,  A61M37/0069 ,  A61M2207/00 ,  B29C39/028 ,  B29C41/02 ,  B29C43/027 ,  B29C43/36 ,  B29C48/09 ,  B29C2043/029 ,  B29K2001/00 ,  B29K2001/08 ,  B29K2105/0035 ,  B29K2995/006 ,  B29L2031/753

Abstract: A solid dose for insertion into the skin of a patient wherein the solid dose has a hollow core. There is also provided a solid dose carrier, a device, a method of manufacturing the solid dose and a method of delivering a solid dose transdermally to a human or animal.

Abstract translation: 用于插入患者皮肤的固体剂量，其中固体剂量具有中空芯。 还提供了固体剂量载体，装置，制备固体剂量的方法和将固体剂量透皮递送给人或动物的方法。

公开(公告)号：US09399102B2

公开(公告)日：2016-07-26

申请号：US13806364

申请日：2011-06-24

Applicant: Bruce H. Dewoolfson ,  Donald Harris ,  Mike Luttrell ,  Gabriel Carpio

Inventor： Bruce H. Dewoolfson ,  Donald Harris ,  Mike Luttrell ,  Gabriel Carpio

IPC: A61M5/42 ,  A61F9/00 ,  A61K38/17 ,  A61K38/45 ,  A61M5/32 ,  A61M5/46 ,  A61K9/00

CPC classification number: A61M5/427 ,  A61F9/0017 ,  A61K9/0048 ,  A61K38/1709 ,  A61K38/45 ,  A61M5/32 ,  A61M5/3287 ,  A61M5/46

Abstract: The present disclosure is directed to an injector device for delivering an ophthalmic solution to a cornea of an eye. The device may include a base configured to contact part of the eye, and a needle connected to the base, wherein needle may deliver the ophthalmic solution to the cornea.

Abstract translation: 本公开涉及用于将眼用溶液递送到眼睛的角膜的注射器装置。 该装置可以包括构造成接触眼睛的一部分的基部和连接到基部的针，其中针可以将眼用溶液递送到角膜。

公开(公告)号：US09381308B2

公开(公告)日：2016-07-05

申请号：US13992991

申请日：2011-12-08

Applicant: Kerstine Hemmann ,  Stephen Minshull ,  Michael Heald ,  Graham Jay

Inventor： Kerstine Hemmann ,  Stephen Minshull ,  Michael Heald ,  Graham Jay

IPC: A61M5/32 ,  A61M5/34 ,  A61M5/42 ,  A61M5/31

CPC classification number: A61M5/32 ,  A61M5/326 ,  A61M5/3271 ,  A61M5/348 ,  A61M5/425 ,  A61M2005/3103 ,  A61M2005/3104

Abstract: The invention relates to an injection supporting device for a syringe. The syringe comprises a cartridge for a medicament and may comprise an injection needle extending in a z-direction from the cartridge to dispense the contents of the cartridge. Alternatively the injection needle may be part of the injection supporting device itself. The injection supporting device comprises a housing to receive at least a part of the cartridge, a needle shield and a resilient member coupled to the needle shield and the housing. The needle shield comprises a distal portion and a proximal portion, a distal opening in a front end of the distal portion and a needle guide for guiding the injection needle towards the distal opening. The needle shield is slidably attached to the housing and slidable relative to the housing along the z-direction between a guarding position covering a tip of the injection needle and an injection position in which a front end portion of the injection needle extends through the distal opening of the needle shield. The resilient member urges the needle shield towards the guarding position.

Abstract translation: 本发明涉及一种用于注射器的注射支撑装置。 注射器包括用于药物的药筒，并且可以包括从药筒沿z方向延伸的注射针，以分配药筒的内容物。 或者，注射针可以是注射支撑装置本身的一部分。 注射支撑装置包括用于容纳药筒的至少一部分的外壳，针护罩和联接到针护罩和外壳的弹性构件。 针罩包括远侧部分和近端部分，远侧部分的前端中的远端开口和用于将注射针引向远侧开口的针引导件。 针护罩可滑动地附接到壳体并且可以沿着Z方向在覆盖注射针的尖端的防护位置和注射位置之间相对于壳体滑动，其中注射针的前端部分延伸穿过远端开口 的针罩。 弹性构件将针护罩推向保护位置。

公开(公告)号：US09370626B2

公开(公告)日：2016-06-21

申请号：US13503778

申请日：2010-11-24

Applicant: Malisa Sarntinoranont ,  Chris Batich ,  Brad Willenberg ,  Erik Hagel ,  Louis C. Vazquez

Inventor： Malisa Sarntinoranont ,  Chris Batich ,  Brad Willenberg ,  Erik Hagel ,  Louis C. Vazquez

IPC: A61M5/32 ,  A61L31/10 ,  A61L31/16 ,  A61M25/00 ,  A61B17/00

CPC classification number: A61L31/10 ,  A61B10/0233 ,  A61B2017/00898 ,  A61L31/145 ,  A61L31/16 ,  A61L2300/606 ,  A61L2420/08 ,  A61M5/158 ,  A61M5/32 ,  A61M25/0045 ,  C08L71/02 ,  C08L29/04

Abstract: Apparatus and methods for blocking needle tracts are disclosed. In some embodiments, the needle tracts are blocked by using a needle that includes an elongated shaft that defines an outer surface, and a polymer coating applied to the outer surface of the shaft, the coating being adapted to block the tract formed by insertion of the needle into an object.

Abstract translation: 公开了用于阻塞针管的装置和方法。 在一些实施例中，通过使用包括限定外表面的细长轴和施加到轴的外表面的聚合物涂层的针来阻止针束，所述涂层适于阻挡通过插入 针入一个物体。

公开(公告)号：US09345641B2

公开(公告)日：2016-05-24

申请号：US13854348

申请日：2013-04-01

Applicant: TEVA MEDICAL LTD.

Inventor： Menachem Kraus ,  Eli Shemesh

IPC: A61J1/20 ,  A61M5/162 ,  A61J1/10 ,  A61J1/14 ,  A61M39/02 ,  A61M39/22

CPC classification number: A61M39/1011 ,  A61J1/10 ,  A61J1/1406 ,  A61J1/1475 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2017 ,  A61J1/2034 ,  A61J1/2055 ,  A61J1/2058 ,  A61J1/2062 ,  A61J1/2072 ,  A61J1/2075 ,  A61J1/2082 ,  A61J1/2089 ,  A61J1/2096 ,  A61J1/22 ,  A61M5/162 ,  A61M5/32 ,  A61M39/02 ,  A61M39/223 ,  A61M2005/1623 ,  A61M2039/0027 ,  A61M2039/0036 ,  A61M2039/1072 ,  A61M2039/1077 ,  A61M2205/75

Abstract: A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.

公开(公告)号：US20160129160A1

公开(公告)日：2016-05-12

申请号：US14988186

申请日：2016-01-05

Applicant: COKI ENGINEERING INC.

Inventor： Akira Yotsutsuji

IPC: A61L31/04 ,  B29D7/01

CPC classification number: A61L31/048 ,  A61L31/06 ,  A61M5/31 ,  A61M5/3129 ,  A61M5/31513 ,  A61M5/32 ,  A61M2005/3131 ,  B29D7/01 ,  B29K2027/18 ,  B29K2105/251

Abstract: A method to make a PTFE skived film capable of exhibiting, with a single layer, sliding properties, barrier properties with regard to a liquid contact surface, and excellent tear resistance during injection molding. This skived film is obtained by cutting a polytetrafluoroethylene block or a modified polytetrafluoroethylene block subjected to a thermal fusion treatment under reduced pressure or subjected to a pressurized thermal fusion treatment after being subjected to fusion under reduced pressure.

Abstract translation: 制造能够以单层显示滑动性能，液体接触表面的阻隔性以及注射成型时优异的抗撕裂性的PTFE刮片的方法。 通过在减压下进行热熔融处理的聚四氟乙烯嵌段或改性聚四氟乙烯嵌段进行切割，或在减压下进行加压热熔融处理后，得到该刮膜。

公开(公告)号：US20160128686A1

公开(公告)日：2016-05-12

申请号：US15000625

申请日：2016-01-19

Applicant: Avent, Inc.

Inventor： John Anthony Rotella ,  Nathan Christopher Griffith ,  Lanita Grayce Cox ,  Donald Jay McMichael

IPC: A61B17/04 ,  A61M5/32

CPC classification number: A61B17/0401 ,  A61B17/3496 ,  A61B2017/00477 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2090/034 ,  A61B2090/037 ,  A61B2090/0801 ,  A61M5/32 ,  A61M2005/3212

Abstract: A blunted safety needle is provided, which includes a hollow needle having a sharp distal tip and a stylus having a blunted end. The stylus is positioned within at least a portion of the needle. After the needle is used to deliver or deploy a substance and/or a device, the blunted end of the stylus is positioned to extend through the sharp distal tip of the needle and un-releaseably lock into position, thereby providing a blunted safety needle assembly.

公开(公告)号：US20160121091A1

公开(公告)日：2016-05-05

申请号：US14892265

申请日：2014-05-22

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Scott A. Burton ,  Chin-Yee Ng ,  Richard R. Mathias ,  Thomas D. R. Ford

IPC: A61M37/00

CPC classification number: A61M37/0015 ,  A61M5/24 ,  A61M5/32 ,  A61M5/3202 ,  A61M5/322 ,  A61M2005/2414 ,  A61M2037/0023 ,  A61M2037/003 ,  A61M2037/0061

Abstract: A microneedle injection apparatus comprising a dual cover. The apparatus can include a housing having a base and a cavity; a microneedle array comprising a first side comprising a plurality of microneedles; and a microneedle array holder configured to hold a microneedle array and located in the housing. The microneedle array holder can be movable between a retracted position, and an extended position. The apparatus can further include a cover (113) configured to be positioned to cover the opening (115) in the base (112) of the housing. The cover can include (i) a first portion (140) configured to cover at least a portion of the base of the housing adjacent the opening, and (ii) a second portion (142) configured to be received in the cavity of the housing and further configured to cover the plurality of microneedles on the microneedle array when the microneedle array holder is in the retracted position.

Abstract translation: 一种包括双层盖的微针注射装置。 该装置可以包括具有底座和空腔的壳体; 微针阵列，包括包括多个微针的第一侧; 以及配置成保持微针阵列并位于壳体中的微针阵列保持器。 微针阵列保持器可以在缩回位置和延伸位置之间移动。 该装置还可以包括构造成定位成覆盖壳体的基部（112）中的开口（115）的盖（113）。 所述盖可以包括（i）第一部分（140），其构造成覆盖邻近所述开口的所述壳体的所述基部的至少一部分，以及（ii）构造成容纳在所述壳体的空腔中的第二部分 并且还被配置为当微针阵列保持器处于缩回位置时覆盖微针阵列上的多个微针。

公开(公告)号：US20160030683A1

公开(公告)日：2016-02-04

申请号：US14776699

申请日：2014-03-14

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： Margaret Taylor ,  David Feygin ,  Elizabeth Nelson ,  Bart Peterson ,  Karthik Ranganathan ,  Richard Byrd

IPC: A61M5/34 ,  A61M5/142

CPC classification number: A61M5/345 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/168 ,  A61M5/3155 ,  A61M5/32 ,  A61M37/0015 ,  A61M2205/33 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3375 ,  A61M2205/3553 ,  A61M2205/3561 ,  A61M2205/3569 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52

Abstract: Smart sensors are employed to determine one or more of drug identification, dose, flow rate, concentration, agglomeration, and degradation and/or other characteristics of drug administration that can be detected via sensing technology. A smart sensor(s) can be coupled to or retrofitted onto injection pen injectors and/or drug delivery cartridges and/or infusion sets or cannulae, enabling infusion sets, pen injector systems or drug delivery cartridges to improve tracking of drug self-administration and stop medication errors that occur primarily through self or automated injection (e.g., due to incorrect or incomplete dosing, excessive dose or rate, incorrect drug, or drug degradation).

Abstract translation: 使用智能传感器来确定可以通过感测技术检测的药物鉴定，剂量，流速，浓度，聚集和降解和/或药物施用的其它特征中的一种或多种。 智能传感器可以耦合到或改装到注射笔注射器和/或药物递送药筒和/或输液器组或套管上，使得输液器，笔注射器系统或药物递送药筒能够改善药物自我管理的跟踪， 停止主要通过自身或自动注射（例如，由于不正确或不完全的给药，过量的剂量或速率，不正确的药物或药物降解）而发生的药物错误。