利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

73 条记录 (耗时 0.027 秒)

    Biomaterial Compositions and Methods of Use
    53.
    发明申请
    Biomaterial Compositions and Methods of Use 审中-公开
    生物材料组合物和使用方法

    公开(公告)号：US20110243913A1

    公开(公告)日：2011-10-06

    申请号：US13081192

    申请日：2011-04-06

    申请人： James San Antonio

    发明人： James San Antonio

    IPC分类号： A61K33/42 ,  A61K38/45 ,  A61P19/08

    CPC分类号： A61K38/45 ,  A61K33/42 ,  A61K38/39 ,  A61K45/06 ,  A61K2300/00

    摘要： The invention relates to biomaterial compositions and methods for promoting bone regeneration and hemostasis. The invention also relates to compositions and methods for promoting wound healing. In various embodiments, the compositions comprise crosslinkable collagen molecules and calcium phosphate suitable for bone regeneration. In various embodiments, the compositions comprise crosslinkable collagen molecules suitable for promoting hemostasis or wound healing; or suitable as tissue sealants. In some embodiments, the compositions contain additional agents, including biological agents.

    摘要翻译： 本发明涉及用于促进骨再生和止血的生物材料组合物和方法。 本发明还涉及用于促进伤口愈合的组合物和方法。 在各种实施方案中，组合物包含适于骨再生的可交联胶原分子和磷酸钙。 在各种实施方案中，组合物包含适于促进止血或伤口愈合的可交联胶原分子; 或适合作为组织密封剂。 在一些实施方案中，组合物含有另外的试剂，包括生物试剂。

    Mixing system and valve assembly
    55.
    发明授权
    Mixing system and valve assembly 有权

    公开(公告)号：US10143982B2

    公开(公告)日：2018-12-04

    申请号：US15687879

    申请日：2017-08-28

    申请人： Orthovita, Inc.

    发明人： John A. Gettings ,  Matthew B. Havener ,  Stephen E. McIlhenny

    IPC分类号： B01F5/06 ,  B01F13/00 ,  A61L27/10 ,  A61L27/12 ,  A61L27/22 ,  A61L27/24 ,  A61L27/38 ,  A61L27/54 ,  B01F15/02

    摘要： A mixing system is disclosed in which the system comprises a source of bone-graft or bone-graft-substitute material, a liquid source, and a vacuum source, at least one of the source of bone-graft or bone-graft-substitute material and the liquid source being in communication with the vacuum source. A valve assembly also forms part of the system, the valve assembly having a valve movable between a first position in which a first fluid passageway is created between the source of bone-graft or bone-graft-substitute material and the vacuum, and a second position in which a second fluid passageway is created between the source of bone-graft or bone-graft-substitute material and the liquid source, wherein, in the second position, the valve seals off the first fluid passageway, the vacuum source being adapted to generate a negative-pressure environment, relative to atmospheric pressure, within the valve assembly while the valve is in the first position. Methods of utilizing the aforementioned system are also disclosed.

    Bone graft materials containing calcium phosphate and chitosan
    60.
    发明授权
    Bone graft materials containing calcium phosphate and chitosan 有权
    含磷酸钙和壳聚糖的骨移植材料

    公开(公告)号：US09040093B2

    公开(公告)日：2015-05-26

    申请号：US13801044

    申请日：2013-03-13

    申请人： Orthovita, Inc.

    发明人： Kristi L. Wagner

    IPC分类号： A61K33/42 ,  A61K31/722 ,  A61K38/39

    CPC分类号： A61K33/42 ,  A61K31/722 ,  A61K38/39 ,  A61L27/46 ,  A61L27/56 ,  A61L2430/02 ,  A61K2300/00 ,  C08L5/08 ,  C08L89/06

    摘要： Described herein are materials and methods for increasing the osteoconductivity of a bone graft material, reducing the risk of infection at a surgical site, and increasing hemostasis. The bone graft materials described herein contain calcium phosphate and a form of chitin. In another embodiment the bone graft materials further comprises collagen. Chitin has been demonstrated to provide increased rate of new calcium phosphate growth, increased hemostasis, as well as antimicrobial properties. Various methods for manufacturing the bone graft materials described herein are also contemplated.

    摘要翻译： 本文描述了用于增加骨移植材料的骨传导性的材料和方法，降低手术部位感染的风险，并增加止血。 本文所述的骨移植物质包含磷酸钙和甲壳质的形式。 在另一个实施方案中，骨移植材料还包括胶原。 已证明甲壳质素能够提供新的磷酸钙生长速率，增加的止血效果以及抗菌性能。 还考虑了用于制造本文所述的骨移植材料的各种方法。