摘要:
An apparatus for separating components and a method of separating components using the apparatus are provided. The apparatus includes: a main chamber which contains a sample that is separated into a plurality of layers by a centrifugal force; a component separating chamber which is connected to the main chamber, and receives a specific layer including specific components among the plurality of layers; a first channel which connects the component separating chamber to the main chamber; and a first channel valve which is disposed in the first channel to control a liquid flowing through the first channel.
摘要:
An apparatus for loading cartridges holding reactants into reactant chambers of a reactor is provided. The apparatus includes: at least one guide rail which transfers a cartridge; an extraction unit comprising at least one storage portion and a blocking portion, the extraction unit moving between a first position in which the blocking portion blocks an outlet of the guide rail and a second position in which the cartridge is output through the outlet of the guide rail and stored by the storage portion; a transfer unit which moves the reactor so that a chamber of the reactor is aligned with the storage portion; and an insertion unit which moves the cartridge from the storage portion into the chamber of the reactor.
摘要:
Provided are a nucleic acid purification apparatus including a chamber that includes an inlet and an outlet, at least two electrodes that defines the chamber and form an electric field, a photovoltaic device that applies a bias to the electrodes, a microfluidic apparatus including the same, and a method of purifying a nucleic acid using the nucleic acid purification apparatus. The nucleic acid purification apparatus includes the photovoltaic device and the conductive transparent electrodes, thus operating independently, and a PCR buffer can be used as an eluate for the nucleic acid. As a result, the nucleic acid purification apparatus can be integrated, and by using the apparatus, a fast and simplified purification can be obtained. The microfludic apparatus including the nucleic acid purification apparatus can operate independently, and perform the purification of the nucleic acid and a PCR at the same time. As a result, the microfluidic apparatus can be miniaturized and automated.
摘要:
A method for manufacturing a biochip and a biochip manufactured by the method are provided. In the biochip manufacturing method, a star-like polyethylene glycol derivative having an epoxy group at its terminal is reacted with a low molecular weight hydrophilic polymer to form a matrix, and a probe is covalently bound to the matrix and immobilized on a solid substrate. The biochip has a 3-dimensional structure where it spatially protrudes from its surface and improved chip sensitivity. In addition, the biochip can be conveniently and efficiently manufactured using an aqueous solution at low costs.
摘要:
A method of manufacturing a microarray by non-contact spotting a biomolecular solution onto a surface of a solid support using a thermally driven print head. The thermally driven print head used to manufacture the microarray includes a discharge chamber filled with the biomolecular solution to be spotted and being substantially semispherical.
摘要:
Provided are a centrifugal microfluidic device having a sample distribution structure and a centrifugal microfluidic system including the centrifugal microfluidic device. The centrifugal microfluidic device includes: a rotatable platform; a sample chamber which is disposed in the rotatable platform and houses a fluid sample; a distribution channel connected to an outlet of the sample chamber; a valve which is disposed in the outlet of the sample chamber; a plurality of non-vented reaction chambers which are disposed in the rotatable platform outside of the distribution channel in the radial direction; and a plurality of inlet channels connecting the distribution channel with the reaction chambers.
摘要:
Provided is a method for noncovalently immobilizing a biomolecule on a solid substrate, including: providing a solid substrate having a first functional group attached thereto, the first functional group having a hydrogen bond donating ability; and reacting a mixture of a compound having a hydrogen bond accepting ability and a biomolecule functionalized with a second functional group, with the surface of the substrate, the second functional group having a hydrogen bond donating ability, in order to noncovalently immobilize the biomolecule on the substrate.
摘要:
Provided are a microarray substrate comprising a solid substrate coated with a chemical having a functional residue represented by Formula 1 or 2 below, a method of analyzing a biomolecule using the microarray substrate, and a lab-on-a-chip comprising the microarray substrate: wherein n, the structure within brackets [ ], R1, R2, R3, R10, n and l are as defined in the specification.
摘要:
An apparatus for separating components and a method of separating components using the apparatus are provided. The apparatus includes: a main chamber which contains a sample that is separated into a plurality of layers by a centrifugal force; a component separating chamber which is connected to the main chamber, and receives a specific layer including specific components among the plurality of layers; a first channel which connects the component separating chamber to the main chamber; and a first channel valve which is disposed in the first channel to control a liquid flowing through the first channel.
摘要:
A phase transition type valve is provided. The valve includes a phase transition material filled and hardened in a section of a channel and a tube expanding region which has a larger cross-sectional area than the channel formed at both ends of the section in which the phase transition material is hardened.