公开(公告)号：US20050214813A1

公开(公告)日：2005-09-29

申请号：US11013400

申请日：2004-12-17

申请人： Toshio Ota ,  Takao Isogai ,  Tetsuo Nishikawa ,  Yuri Hio ,  Mayako Yamazaki ,  Susumu Satoh ,  Hiroyuki Arakawa ,  Masahiko Morita

发明人： Toshio Ota ,  Takao Isogai ,  Tetsuo Nishikawa ,  Yuri Hio ,  Mayako Yamazaki ,  Susumu Satoh ,  Hiroyuki Arakawa ,  Masahiko Morita

IPC分类号： A61K38/00 ,  A61P25/00 ,  A61P25/28 ,  C07K14/47 ,  C07K14/505 ,  C07K14/52 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N15/12 ,  C12N15/16 ,  C12P21/08 ,  C12Q1/68 ,  C07H21/04 ,  C12N9/64

CPC分类号： C07K14/4702 ,  A01K2217/05 ,  A61K38/00 ,  C07K14/4711 ,  C07K14/4747 ,  C07K14/505 ,  C07K14/524

摘要： The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-β protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-β protein; and therapeutic agents for treating or preventing Alzheimer's diseases comprising a compound that regulates the activity of a protein suppressing or promoting the aggregation or deposition of amyloid-β protein.

摘要翻译： 本发明提供：抑制或促进淀粉样蛋白-β蛋白的聚集或沉积的蛋白质; 编码蛋白质的多核苷酸; 筛选抑制或促进淀粉样蛋白-β蛋白的聚集或沉积的化合物的方法; 以及用于治疗或预防阿尔茨海默病的治疗剂，其包含调节蛋白质抑制或促进淀粉样蛋白-β蛋白的聚集或沉积的活性的化合物。

公开(公告)号：US06884388B2

公开(公告)日：2005-04-26

申请号：US10344535

申请日：2001-08-31

申请人： Yoshihiro Ozaki ,  Toshimitsu Nagaya ,  Atsushi Miyazaki ,  Susumu Satoh ,  Mineo Muraki ,  Setsuo Kakihara ,  Toshihiro Kasamo

发明人： Yoshihiro Ozaki ,  Toshimitsu Nagaya ,  Atsushi Miyazaki ,  Susumu Satoh ,  Mineo Muraki ,  Setsuo Kakihara ,  Toshihiro Kasamo

IPC分类号： C21D8/02 ,  C22C38/00 ,  C22C38/20 ,  C22C38/22 ,  C22C38/24 ,  C22C38/26 ,  C22C38/38 ,  C22C38/42 ,  C22C38/58 ,  C22C38/28

CPC分类号： C22C38/26 ,  C21D8/0205 ,  C21D8/0263 ,  C22C38/001 ,  C22C38/20 ,  C22C38/22 ,  C22C38/24 ,  C22C38/38 ,  C22C38/42 ,  C22C38/58

摘要： A martensitic stainless steel sheet which is hard to be softened by tempering caused by heating during the use of a disk brake, can maintain the predetermined hardness, and has excellent punching workability, bending workability before quenching, and a particularly small shear drop, and in which a predetermined hardness after quenching is constantly achieved, in a low carbon martensitic stainless steel sheet used only after quenching. Specifically, the sheet contains, on the basis of mass percent, 0.030% to 0.100% C; 0.50% or less of Si; 1.00% to 2.50% Mn; more than 10.00% to 15.00% Cr; at least one selected from the group consisting of 0.01% to 0.50% Ti, 0.01% to 0.50% V, 0.01% to 1.00% Nb, and 0.01% to 1.00% Zr; N in an amount defined by the following expression, N: 0.005% to (Ti+V)×14/50+(Nb+Zr)×14/90; and the balance being Fe and incidental impurities.

摘要翻译： 在使用盘式制动器时由于加热而难以软化的马氏体不锈钢板可以保持预定的硬度，并且具有优异的冲压加工性，淬火前的弯曲加工性和特别小的剪切降低 在淬火后使用的低碳马氏体系不锈钢板中，不断地实现淬火后的预定硬度。 具体而言，以质量％计含有0.030〜0.100％的C; 0.50％以下的Si; 1.00％至2.50％Mn; 超过10.00％至15.00％的Cr; 选自由0.01％至0.50％Ti，0.01％至0.50％V，0.01％至1.00％Nb和0.01％至1.00％Zr组成的组中的至少一种; N以下列表达式定义：N：0.005％至（Ti + V）x14 / 50 +（Nb + Zr）x14 / 90; 余量为Fe和杂质。

公开(公告)号：US06426039B2

公开(公告)日：2002-07-30

申请号：US09892370

申请日：2001-06-27

申请人： Junichiro Hirasawa ,  Atsushi Miyazaki ,  Mineo Muraki ,  Susumu Satoh

发明人： Junichiro Hirasawa ,  Atsushi Miyazaki ,  Mineo Muraki ,  Susumu Satoh

IPC分类号： C22C3852

CPC分类号： C22C38/06 ,  C22C38/001 ,  C22C38/004 ,  C22C38/44 ,  C22C38/46 ,  C22C38/48 ,  C22C38/52 ,  C22C38/54

摘要： Ferritic stainless steel comprising all three of Co, V, and B, having a Co content of about 0.01 mass % to about 0.3 mass %, a V content of about 0.01 mass % to about 0.3 mass %, and a B content of about 0.0002 mass % to about 0.0050 mass %, and having superior secondary working embrittleness resistance and superior high temperature fatigue characteristics.

公开(公告)号：US06312533B1

公开(公告)日：2001-11-06

申请号：US09720864

申请日：2001-01-02

申请人： Takeshi Yokota ,  Kenji Takao ,  Susumu Satoh ,  Haruhiko Ishizuka ,  Masaharu Ikeda

发明人： Takeshi Yokota ,  Kenji Takao ,  Susumu Satoh ,  Haruhiko Ishizuka ,  Masaharu Ikeda

IPC分类号： C23C2800

CPC分类号： A61L2/238 ,  C23C18/42

摘要： The present invention provides a BA-finished stainless steel product having superior antibacterial properties and corrosion resistance and a method for producing the same. Specifically, after a stainless steel product is subjected to BA treatment, the stainless steel product is immersed in a solution containing Ag ions having a concentration of 0.0001 to 1.0 mol/l so that a BA film contains, in area percentage, 0.0002 to 0.05% of Ag particles and Ag compounds, and further, stainless steel product contains 0.001 to 0.10% by weight of Ag and optionally further contains 0.001 to 0.30% by weight of V.

摘要翻译： 本发明提供具有优异的抗菌性和耐腐蚀性的BA成品不锈钢制品及其制造方法。 具体地说，在对不锈钢制品进行BA处理后，将不锈钢制品浸渍在含有浓度为0.0001〜1.0mol / l的Ag离子的溶液中，使得BA膜的面积百分比为0.0002〜0.05％ 的Ag颗粒和Ag化合物，此外，不锈钢产品含有0.001至0.10重量％的Ag，并且任选地还包含0.001至0.30重量％的V。

公开(公告)号：US5796712A

公开(公告)日：1998-08-18

申请号：US780717

申请日：1997-01-08

申请人： Mineo Moribe ,  Miyozo Maeda ,  Susumu Satoh ,  Kyoko Miyabe

发明人： Mineo Moribe ,  Miyozo Maeda ,  Susumu Satoh ,  Kyoko Miyabe

IPC分类号： G11B7/0045 ,  G11B7/005 ,  G11B7/007 ,  G11B7/013 ,  G11B7/09 ,  G11B11/105 ,  G11B27/19 ,  G11B27/24 ,  G11B27/30 ,  G11B7/24

CPC分类号： G11B11/10597 ,  G11B27/19 ,  G11B27/24 ,  G11B27/3027 ,  G11B7/00718 ,  G11B7/00745 ,  G11B11/10565 ,  G11B7/0045 ,  G11B7/005 ,  G11B7/007 ,  G11B7/0938 ,  G11B7/24085

摘要： An optical disk is made up of a disk-shaped substrate having a surface, a first track and a second track provided on the surface of the substrate, where the first and second tracks are two mutually adjacent concentric tracks or two mutually adjacent track turns of a single spiral track, the first track extends along a first center line and the second track extends along a second center line, and an identification signal recording part extending along a third center line and prerecorded with an identification signal including at least a sector number and a track number for identifying a position on the optical disk. The third center line is arranged between the first and second center lines, and the identification signal prerecorded in the identification signal recording part is common to the first and second tracks on both sides of the identification signal recording part.

摘要翻译： 光盘由具有表面的盘状基板，设置在基板的表面上的第一轨道和第二轨道构成，其中第一和第二轨道是两个相互相邻的同心轨道或两个相互相邻的轨道匝 第一轨道沿着第一中心线延伸，第二轨道沿着第二中心线延伸，以及识别信号记录部分，沿着第三中心线延伸并且预先记录有至少包括扇区号的识别信号和 用于识别光盘上的位置的轨道号。 第三中心线布置在第一和第二中心线之间，并且预先记录在识别信号记录部分中的识别信号对于识别信号记录部分两侧的第一和第二轨道是共同的。

公开(公告)号：US5292383A

公开(公告)日：1994-03-08

申请号：US808753

申请日：1991-12-17

申请人： Kazunori Osawa ,  Susumu Satoh ,  Toshiyuki Kato ,  Hideo Abe ,  Keiji Nishimura

发明人： Kazunori Osawa ,  Susumu Satoh ,  Toshiyuki Kato ,  Hideo Abe ,  Keiji Nishimura

IPC分类号： C21D8/02 ,  C21D9/48 ,  C22C38/00 ,  C22C38/16

CPC分类号： C22C38/16

摘要： A steel sheet for porcelain enameling having improved press formability and enameling properties comprises particular amounts of C, Mn, B, Cu, Al, O, N, and P or further Ti and Nb and the balance being Fe and inevitable impurities and is produced by hot rolling a slab of steel having a chemical composition as mentioned above as a starting material, cold rolling the resulting hot rolled sheet at a reduction of not less than 70%, and then subjecting the resulting cold rolled sheet to a continuous annealing at a heating temperature of not lower than 800.degree. C. but not higher than A.sub.c3 transformation point.

摘要翻译： 具有改进的压制成形性和搪瓷性能的瓷搪瓷用钢板包含特定量的C，Mn，B，Cu，Al，O，N和P，或另外的Ti和Nb，余量为Fe和不可避免的杂质，并由 将具有上述化学成分的钢板热轧成原料，将得到的热轧板以不低于70％的压下率进行冷轧，然后使所得到的冷轧板在加热下进行连续退火 温度不低于800℃，但不高于Ac3转化点。

公开(公告)号：US4973367A

公开(公告)日：1990-11-27

申请号：US454923

申请日：1989-12-22

申请人： Saiji Matsuoka ,  Susumu Satoh ,  Toshiyuki Katoh ,  Hideo Abe ,  Ikuo Yarita

发明人： Saiji Matsuoka ,  Susumu Satoh ,  Toshiyuki Katoh ,  Hideo Abe ,  Ikuo Yarita

IPC分类号： C21D8/04

CPC分类号： C21D8/0426 ,  C21D8/0431 ,  C21D8/0463 ,  C21D8/0478

摘要： A method of manufacturing a steel sheet having excellent deep-drawability. A steel blank is rolled into a steel sheet having a predetermined thickness. The steel contains C: not more than 0.008 wt %, Si: not more than 0.5 wt %, Mn: not more than 1.0 wt %, P: not more than 0.15 wt %, S: not more than 0.02 wt %, Al: 0.010 to 0.10 wt %, N: not more than 0.008 wt %, and at least one element selected from the group consisting of Ti and Nb which is contained in an amount satisfying the relationship of 1.2 (C/12+N/14).ltoreq.(Ti/48+Nb/93). In at least one pass, rolling is conducted within a temperatures range lower than the Ar3 transformation point but not lower than 500.degree. C., in such a manner that the roll radius R (mm) and the blank thickness t (mm) before rolling by rolls satisfy the relationships of R.ltoreq.200 and R.sup.2 .times..sqroot.t.ltoreq.100000, and the total rolling reduction at temperature lower than the Ar3 transformation point is not lower than 60%. The hot-rolled steel sheet possesses a high level of Lankford value, and is free from cold-working embrittlement. The method may include the step of obtaining, after the rolling, pickling, annealing and hot dip galvanizing under certain conditions, a surface-treated steel sheet having excellent deep-drawability.

公开(公告)号：US4861390A

公开(公告)日：1989-08-29

申请号：US835052

申请日：1986-02-28

申请人： Susumu Satoh ,  Saiji Matsuoka ,  Takashi Obara ,  Kozo Tsunoyama ,  Toshio Irie

发明人： Susumu Satoh ,  Saiji Matsuoka ,  Takashi Obara ,  Kozo Tsunoyama ,  Toshio Irie

IPC分类号： C21D8/04

CPC分类号： C21D8/0426 ,  B21B2201/04 ,  C21D8/0431 ,  C21D8/0463 ,  C21D8/0478

摘要： A method of manufacturing formable as-rolled thin steel sheets having excellent ridging resistance and other properties is disclosed, which comprises rolling a low carbon steel to a given thickness without cold rolling and recrystallization annealing steps. In this rolling, at least one rolling pass is carried out within a given temperature range at high draft and high strain rate.

摘要翻译： 公开了一种制造具有优异的抗皱性等特性的可成形的轧制薄钢板的方法，其包括在不进行冷轧和再退火退火步骤的情况下将低碳钢轧制至给定厚度。 在该轧制中，在给定的温度范围内，在高吃水和高应变率下进行至少一个轧制道次。

公开(公告)号：US4847260A

公开(公告)日：1989-07-11

申请号：US113352

申请日：1987-10-26

申请人： Yoko Abe ,  Susumu Satoh ,  Mitsuhiko Hori ,  Naoko Yamanaka

发明人： Yoko Abe ,  Susumu Satoh ,  Mitsuhiko Hori ,  Naoko Yamanaka

IPC分类号： A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/18 ,  A61K47/20 ,  A61K47/22 ,  C07D213/79 ,  C07D213/80

CPC分类号： C07D213/79 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/18 ,  A61K47/20 ,  A61K47/22 ,  A61K9/0014 ,  C07D213/80

摘要： A composition for percutaneous administration containing a nicotinic ester represented by formula (I) ##STR1## or an isonicotinic ester represented by formula (II) ##STR2## wherein R and R' each represents an alkyl group having 5 or more carbon atoms,with or without a specific polar compound. The composition improves percutaneous absorption of an active ingredient.

摘要翻译： 用于经皮给药的组合物，其含有由式（I）表示的烟酸酯或由式（II）表示的异烟酸酯其中R和R'各自表示具有5或 更多的碳原子，有或没有特定的极性化合物。 该组合物改善活性成分的经皮吸收。

公开(公告)号：US4793401A

公开(公告)日：1988-12-27

申请号：US939543

申请日：1986-12-09

申请人： Saiji Matsuoka ,  Susumu Satoh ,  Takashi Obara ,  Kozo Tsunoyama ,  Hideo Abe

发明人： Saiji Matsuoka ,  Susumu Satoh ,  Takashi Obara ,  Kozo Tsunoyama ,  Hideo Abe

IPC分类号： B21B1/28 ,  B21B1/34 ,  B21B1/40 ,  B21B1/46 ,  B21B9/00 ,  C21D8/02 ,  B21B13/22 ,  B22D11/12

CPC分类号： B21B1/46 ,  B21B1/28 ,  B21B1/34 ,  C21D8/0226 ,  B21B1/40 ,  B21B2201/04 ,  B21B2261/20 ,  B21B2275/06 ,  B21B9/00 ,  C21D8/0231 ,  C21D8/0263 ,  Y10T29/49991

摘要： Thin steel sheets having an improved processability are produced when a steel sheet or cast strip obtained through a continuous casting or strip caster process is subjected to a lubrication rolling step at a temperature of from Ar.sub.3 transformation point to 300.degree. C. and a rolling speed of not less than 1,500 m/min. By this method, the cold rolling step or cold rolling-annealing step can be omitted.

摘要翻译： 当通过连续铸造或连续铸造法得到的钢板或铸钢带在Ar 3相变点至300℃的温度下进行润滑轧制步骤时，生产具有改善加工性能的薄钢板，并且轧制速度 不低于1500米/分。 通过该方法，可以省略冷轧工序或冷轧退火工序。