Method of fixing low-molecular compound to solid-phase support
    57.
    发明申请
    Method of fixing low-molecular compound to solid-phase support 有权
    将低分子化合物固定在固相载体上的方法

    公开(公告)号:US20060194251A1

    公开(公告)日:2006-08-31

    申请号:US10551809

    申请日:2004-03-25

    IPC分类号: G01N33/53 B05D3/02

    摘要: A method of fixing a low-molecular compound to a solid-phase support, which comprises a step in which a solution containing a low-molecular compound is brought into contact with a solid-phase support having a photoreactive compound bonded to the surface, a step in which the solution containing a low-molecular compound is evaporated to dryness in the state of being in contact with the solid-phase support, and a step in which the solid-phase support is irradiated with light to form a covalent bond between the photoreactive compound and the low-molecular compound. This fixing method enables a low-molecular compound to be fixed to a solid-phase support without the aid of a functional group.

    摘要翻译: 一种将低分子化合物固定在固相载体上的方法,其包括使含有低分子化合物的溶液与具有与表面结合的光反应性化合物的固相载体接触的步骤, 在与固相载体接触的状态下将含有低分子化合物的溶液蒸发至干的步骤,以及固相支持体在光照射下形成共价键的步骤 光反应性化合物和低分子化合物。 这种固色方法能够使低分子化合物固定在固相载体上而无需官能团的帮助。

    Aluminum printing plates and method of making
    58.
    发明授权
    Aluminum printing plates and method of making 失效
    铝印版及其制作方法

    公开(公告)号:US06664019B2

    公开(公告)日:2003-12-16

    申请号:US09902416

    申请日:2001-07-10

    IPC分类号: G03F7012

    摘要: A method of making improved aluminum printing plates comprising graining the aluminum plates, de-smutting them by treating them with nitric acid solution, then rinsing with hot water, acetating the aluminum plates, and silicating the aluminum plates. The plates are then coated with a photoresist, pattern exposed and developed. The printing plates of the invention have improved characteristics; they have excellent adhesion of the resist in image areas, and ink repellency in non-image areas. The developed printing plates have excellent durability without baking.

    摘要翻译: 一种制造改进的铝印版的方法,包括将铝板磨成板,通过用硝酸溶液处理它们去除它们,然后用热水冲洗,乙酸化铝板和硅化铝板。 然后用光致抗蚀剂涂覆板,图案曝光和显影。 本发明的印版具有改进的特性; 它们在图像区域中具有优异的抗蚀剂粘附性,并且在非图像区域中具有拒墨性。 显影的印版具有优异的耐久性,无需烘烤。

    Chemical functionalization of surfaces
    60.
    发明授权
    Chemical functionalization of surfaces 失效
    表面化学官能化

    公开(公告)号:US6022597A

    公开(公告)日:2000-02-08

    申请号:US966058

    申请日:1997-11-07

    摘要: Methods for covalently modifying surfaces of various substrates are disclosed, along with various substrates having surfaces modified by such methods. Candidate surfaces include various polymeric, siliceous, metallic, allotrophic forms of carbon, and semiconductor surfaces. The surfaces are exposed to a reagent, having molecules each comprising a nitrenogenic group and a functionalizing group, in the presence of energized charged particles such as electrons and ions, photons, or heat, which transform the nitrenogenic reagent to a nitrene intermediate. The nitrene covalently reacts with any of various chemical groups present on the substrate surface, thereby effecting nitrene addition of the functionalizing groups to the substrate surface. The functionalizing groups can then participate in downstream chemistry whereby any of a large variety of functional groups, including biological molecules, can be covalently bonded to the surface, thereby dramatically altering the chemical behavior of the surface. Such functionalizations of the surface can be done in a single reactive step or in multiple reactive steps.

    摘要翻译: 公开了共价修饰各种基材的表面的方法,以及具有通过这些方法修饰的表面的各种基材。 候选表面包括各种聚合物,硅质,金属,同位素形式的碳和半导体表面。 表面暴露于试剂,其具有各自包含硝基衍生基团和官能化基团的分子,在激发带电粒子例如电子和离子,光子或热的存在下,其将硝化试剂转化为硝酸中间体。 所述氮烯与存在于所述基材表面上的各种化学基团共价反应,由此将所述官能团添加到所述基材表面上。 官能化基团然后可以参与下游化学,由此可以将大量各种官能团(包括生物分子)中的任何一个共价键合到表面,从而显着地改变表面的化学行为。 表面的这种功能化可以在单个反应步骤中或在多个反应步骤中进行。