公开(公告)号：US09109591B2

公开(公告)日：2015-08-18

申请号：US13784615

申请日：2013-03-04

Applicant: MEDRAD, INC.

Inventor： Charles Marsh ,  Larry McCutchan

IPC: F04B7/02 ,  F04B43/02 ,  F04B43/12 ,  F04B49/06 ,  F04B49/10

CPC classification number: A61M5/172 ,  A61M5/14228 ,  A61M2205/33 ,  A61M2205/3379 ,  A61M2205/505 ,  A61M2205/52 ,  F04B43/02 ,  F04B43/12 ,  F04B49/065 ,  F04B49/106

Abstract: Methods and systems for dispensing a fluid using an automated fluid delivery system are disclosed. A pump may be configured to force an aliquot of fluid into a fluid delivery channel. A processor may receive values of a property for the aliquot and the source of the aliquot. The processor may use the values to determine the volume of the aliquot. The determined volume is compared by the processor against an expected volume to establish the amount of fluid being pumped by the pump per unit, such as time or revolutions. The processor controls operation of the pump to dispense a predetermined dose based on the amount of fluid being pumped by the pump per unit.

Abstract translation: 公开了使用自动化流体输送系统分配流体的方法和系统。 泵可以被配置成迫使一分液体流入流体输送通道。 处理器可以接收等分试样的属性值和等分试样的来源。 处理器可以使用这些值来确定等分试样的体积。 所确定的体积被处理器与预期体积进行比较，以建立每单位泵泵送的流体的量，例如时间或转数。 处理器控制泵的操作，以基于每单位由泵泵送的流体的量来分配预定剂量。

公开(公告)号：US09101713B2

公开(公告)日：2015-08-11

申请号：US13797959

申请日：2013-03-12

Applicant: MEDRAD, INC.

Inventor： Kevin P. Cowan ,  Barry L. Tucker

IPC: A61M5/315 ,  A61M5/168 ,  A61M5/20 ,  A61M5/00 ,  A61M5/145

CPC classification number: A61M5/3148 ,  A61M5/007 ,  A61M5/14526 ,  A61M5/16877 ,  A61M5/2053 ,  A61M5/3137 ,  A61M5/31515 ,  A61M5/36 ,  A61M5/48 ,  A61M2005/3123 ,  A61M2005/3128 ,  A61M2005/3139 ,  A61M2202/0007

Abstract: Various syringe systems are disclosed. One such syringe system may include a body having a hollow lumen and a distal end, a vacuum chamber disposed within the hollow lumen of the syringe body, a first plunger connected to a distal portion of the vacuum chamber, the first plunger forming a first seal against an inner surface of the syringe body and defining a fluid delivery volume between the first plunger and the distal end of the syringe body, a second plunger disposed within the vacuum chamber, the second plunger forming a second seal against an inner surface of the vacuum chamber and defining a proximal and distal volume compartments within the vacuum chamber, and a piston affixed to the second plunger, the piston configured to move the second plunger within the vacuum chamber, thereby altering a volume of the proximal volume compartment and a volume of the distal volume compartment.

Abstract translation: 公开了各种注射器系统。 一个这样的注射器系统可以包括具有中空内腔和远端的本体，设置在注射器主体的中空腔内的真空室，连接到真空室的远端部分的第一柱塞，第一柱塞形成第一密封件 抵靠注射器主体的内表面并且在第一柱塞和注射器主体的远端之间限定流体输送体积，设置在真空室内的第二柱塞，第二柱塞形成抵靠真空内表面的第二密封 并且限定真空室内的近端和远端容积隔室，以及固定到第二柱塞的活塞，活塞构造成使第二柱塞在真空室内移动，由此改变近端容积隔室的体积和 远端容积室。

公开(公告)号：US20140277007A1

公开(公告)日：2014-09-18

申请号：US13830699

申请日：2013-03-14

Applicant: MEDRAD, INC.

Inventor： Michael J. Bonnette

IPC: A61B17/3203

CPC classification number: A61B17/32037 ,  A61B2017/22039 ,  A61B2017/22041 ,  A61B2017/22079 ,  A61F2/013 ,  A61F2002/016

Abstract: A hydrodynamic catheter includes a catheter body with a catheter lumen and an infusion tube extending within the catheter body, the infusion tube configured for coupling with a fluid source near the catheter proximal portion. An inflow orifice and an outflow orifice are positioned at locations along a catheter body perimeter. A fluid jet emanator is in fluid communication with the infusion tube, where the fluid jet emanator includes one or more jet orifices configured to direct one or more fluid jets through the catheter lumen from near the inflow orifice toward the outflow orifice. A pivot cylinder located along the catheter body perimeter is positioned distal relative to one or more of the fluid jet emanator, the inflow orifice, or the outflow orifice.

Abstract translation: 流体动力导管包括具有导管内腔的导管主体和在导管主体内延伸的输液管，该输液管构造成用于与导管近端部分附近的流体源耦合。 入口孔和流出口位于导管主体周边的位置。 流体喷射发生器与输液管流体连通，其中流体喷射发生器包括一个或多个喷射孔，其构造成将一个或多个流体射流引导通过导管腔从入口孔附近朝向流出孔。 沿着导管主体周边定位的枢轴圆筒相对于流体喷射发生器，流入孔或流出孔中的一个或多个定位在远侧。

公开(公告)号：US20140257015A1

公开(公告)日：2014-09-11

申请号：US13789664

申请日：2013-03-07

Applicant: MEDRAD, INC.

Inventor： James A. AGAMAITE ,  Larry McCUTCHAN

IPC: A61N5/10

CPC classification number: A61N5/1007 ,  A61M5/007 ,  A61M5/1785 ,  A61N2005/1074 ,  G06F19/3468 ,  G21G1/0005

Abstract: Methods and systems for automatically and dynamically determining a dose of a radiopharmaceutical are disclosed. The dose may be determined based on, among other things, radiopharmaceutical information associated with at least one source of a radiopharmaceutical, patient information and schedule information. An estimated radioactivity level may be determined based on an initial radioactivity level, a delivery time, a radioactivity decay rate, and an anticipated arrival time. A volume of the radiopharmaceutical to inject into a patient to deliver a dose of radioactivity may be determined based on the estimated radioactivity level and patient dosing information. An infusion apparatus may operate to inject the patient with the volume of the radiopharmaceutical.

Abstract translation: 公开了用于自动和动态地确定放射性药物剂量的方法和系统。 剂量可以基于除了别的以外，与放射性药物的至少一种来源相关联的放射性药物信息，患者信息和进度信息来确定。 可以基于初始放射性水平，递送时间，放射性衰减速率和预期到达时间来确定估计的放射性水平。 可以基于估计的放射性水平和患者给药信息来确定向患者注射以递送一定剂量放射性的放射性药物的体积。 输注装置可以操作以向患者注射放射性药物的体积。

公开(公告)号：US20140228757A1

公开(公告)日：2014-08-14

申请号：US13764505

申请日：2013-02-11

Applicant: MEDRAD, INC.

Inventor： Mark TROCKI

IPC: A61M5/31

CPC classification number: A61M5/3135 ,  A61M5/3129 ,  A61M5/31511

Abstract: Bent syringes, mounting systems for bent syringes, and devices incorporating bent syringes are described herein. The syringes include a bent cylindrical body bent about a radius and a plunger bent about the radius of the bent cylindrical body and configured and arranged to be received by the proximal open end of the bent cylindrical body and movably disposed within at least a portion of the bent cylindrical body.

Abstract translation: 本文描述弯曲注射器，弯曲注射器的安装系统和结合弯曲注射器的装置。 注射器包括围绕半径弯曲的弯曲圆柱体和围绕弯曲圆柱体的半径弯曲的柱塞，并被构造和布置成被弯曲圆柱体的近端开口端容纳并可移动地设置在弯曲圆柱体的至少一部分内 弯曲的圆柱体。

公开(公告)号：US20140091569A1

公开(公告)日：2014-04-03

申请号：US13632598

申请日：2012-10-01

Applicant: MEDRAD, INC.

Inventor： Michael A. Spohn ,  Cory J. Price ,  Andrew W. Meier

IPC: F16L13/00 ,  B32B37/02

CPC classification number: A61M39/08 ,  A61M39/10 ,  A61M39/12 ,  A61M2039/082 ,  B29C47/0023 ,  B29C47/0028 ,  B29C47/0033 ,  B29C47/021 ,  B29C47/065 ,  B29C2947/92514 ,  B29C2947/92761

Abstract: A high pressure medical connector tubing assembly includes a high pressure medical connector tubing assembly, including a tube element having opposed tube ends and a passageway, an end element overmolded to at least one of the opposed tube ends, the end element having an annular end portion having a preselected length, and a connector element having a connector hub defining a receiving cavity. The preselected length of the annular end portion may be used to pre-control the axial location of stress concentration in the connector hub. A method of forming the high pressure medical connector tubing assembly includes providing a tube element comprising opposed tube ends and a passageway therethrough, overmolding an end element onto at least one of the opposed tube ends, providing a connector element comprising a connector hub defining a receiving cavity, and securing the tube end with the overmolded end element in the receiving cavity.

Abstract translation: 高压医疗连接器管组件包括高压医疗连接器管道组件，其包括具有相对的管端部和通道的管元件，包括模制到至少一个相对的管端部的端部元件，端部元件具有环形端部 具有预定长度，以及具有限定接收腔的连接器毂的连接器元件。 可以使用环形端部的预选长度来预先控制连接器毂中的应力集中的轴向位置。 形成高压医疗连接器管组件的方法包括提供管元件，其包括相对的管端和通过其的通道，将端元件包覆模制在相对的管端中的至少一个上，提供连接器元件，该连接器元件包括限定接收 并且在接收腔中用包覆成型的端部元件固定管端。

公开(公告)号：US20140088494A1

公开(公告)日：2014-03-27

申请号：US14116850

申请日：2012-05-11

Applicant: Medrad, Inc.

Inventor： John D. Shearer, JR. ,  Christopher M. Scutt ,  Walter J. Grumski ,  Michael A. Spohn ,  Jarrell T. McWilliams ,  Arlie D. Long, III ,  Richard C. Morton

IPC: A61M5/00 ,  A61M5/168

CPC classification number: A61M5/16831 ,  A61M5/00 ,  A61M5/007 ,  A61M5/14546 ,  A61M2005/14553 ,  A61M2205/215 ,  A61M2205/50 ,  A61M2205/502

Abstract: A fluid injection system that includes an injector head having a syringe for delivering a fluid to a patient; a mounting structure pivotally connected to the injector head and configured to support the injector head above a surface; and a control system operationally coupled to the injector head for controlling an injection procedure is disclosed. The fluid injection system is provided with various sensors to control various aspects of the fluid injection system, such as the establishment of a reference plane, the determination of a tilt angle of the injector head, and the determination of a temperature of an actuation system of the injector head.

Abstract translation: 一种流体注射系统，其包括具有用于将流体输送给患者的注射器的注射器头部; 安装结构，其枢转地连接到所述注射器头部并且构造成将所述注射器头支撑在表面上方; 并且公开了一种可操作地耦合到喷射头的用于控制喷射程序的控制系统。 流体注射系统设置有各种传感器以控制流体注射系统的各个方面，例如建立参考平面，确定注射器头部的倾斜角度以及确定致动系统的温度 注射头。

公开(公告)号：US20140005699A1

公开(公告)日：2014-01-02

申请号：US13794350

申请日：2013-03-11

Applicant: MEDRAD, INC.

Inventor： Michael J. Bonnette ,  Debra M. Kozak ,  Eric J. Thor

IPC: A61B17/3207

CPC classification number: A61B17/320758 ,  A61B17/320725 ,  A61B2017/22079 ,  A61B2217/005 ,  A61B2217/007

Abstract: An atherectomy and thrombectomy system includes a catheter body extending between proximal and distal catheter portions. The catheter body includes an aspiration lumen extending therein. An atherectomy assembly is coupled with the distal catheter portion and includes a rotatable cutter. A thrombectomy assembly is coupled with the distal catheter portion. The thrombectomy assembly includes a jet body within the aspiration lumen, and inflow and outflow orifices extending through the catheter body and in communication with the aspiration lumen. In a thrombectomy configuration a cyclical flow is generated by the jet body through the outflow and inflow orifices to hydrodynamically abrade thrombus, the cyclical flow entrains thrombus and delivers thrombus into the aspiration lumen. In the atherectomy configuration the rotatable cutter cuts plaque into plaque particulate, and the cyclical flow of the thrombectomy assembly entrains the particulate and delivers the particulate into the aspiration lumen.

Abstract translation: 粥样斑块切除术和血栓切除术系统包括在近端和远端导管部分之间延伸的导管体。 导管主体包括在其中延伸的抽吸腔。 动脉粥样组织切除术组件与远侧导管部分联接并且包括可旋转切割器。 血栓切除术组件与远侧导管部分联接。 血栓切除组件包括抽吸腔内的喷射体，以及延伸穿过导管主体并与抽吸腔连通的流入口和出口孔。 在血栓切除结构中，射流体通过流出孔和流入口产生循环流动以流体动力学研磨血栓，循环流动引起血栓并将血栓输送到抽吸腔。 在粥样斑块切除配置中，可旋转切割器将牙斑切割成斑块颗粒，并且血栓切除术组件的循环流动夹带颗粒并将颗粒输送到抽吸腔中。

公开(公告)号：US20130331635A1

公开(公告)日：2013-12-12

申请号：US13831734

申请日：2013-03-15

Applicant: MEDRAD, INC.

Inventor： Raymond C. HOFFMAN ,  Barry L. TUCKER ,  David H. BERRY ,  Martin J. URAM ,  Douglas DeSCALZI ,  Arthur E. UBER, III

IPC: A61N5/10

CPC classification number: A61N5/1007 ,  A61M5/158 ,  A61M5/162 ,  A61M5/1785 ,  A61M39/10 ,  A61M39/20 ,  A61N2005/1021 ,  A61N2005/1094

Abstract: A device for delivery of a radiopharmaceutical and, in some embodiments, delivery of a pharmaceutical agent are described herein. Various other components for delivery systems including tubing management systems, primer caps, diffusion chambers, radiation shields and syringe shields, and other devices and methods are also described.

Abstract translation: 本文描述了用于递送放射性药物的装置，并且在一些实施方案中，递送药剂。 还描述了用于递送系统的各种其它组件，包括管道管理系统，底漆帽，扩散室，辐射屏蔽和注射器护罩以及其它装置和方法。

公开(公告)号：US20130131585A1

公开(公告)日：2013-05-23

申请号：US13743173

申请日：2013-01-16

Applicant: MEDRAD, INC.

Inventor： Shannon EUBANKS ,  Keith SCHUBERT ,  Peter BRISTOL ,  Patrick VILBRANDT

IPC: A61M25/00 ,  A61M3/02 ,  A61M39/10

CPC classification number: A61M3/0283 ,  A61B17/3207 ,  A61B17/320758 ,  A61B2017/00199 ,  A61B2017/00482 ,  A61B2017/22079 ,  A61M1/0064 ,  A61M5/14232 ,  A61M25/0021 ,  A61M39/10 ,  A61M2205/12 ,  A61M2205/50 ,  A61M2209/084

Abstract: Interventional catheter assemblies, operating systems and adaptive interface components allow operation of a variety of interventional catheter assemblies, including infusion catheters, aspiration catheters and interventional catheters that provide both infusion and aspiration, using a common control console housing infusion and aspiration systems. Adaptive tubing cassettes having a handle and one or more preformed tubing loops route aspiration and/or infusion tubing in a predetermined configuration to mate with aspiration and infusion systems on a control console.

Abstract translation: 介入导管组件，操作系统和自适应界面部件允许使用共同的控制台进行输液和抽吸系统的各种介入导管组件（包括输液导管，抽吸导管和提供输注和抽吸的介入导管）的操作。 具有手柄和一个或多个预成型管环的自适应管道盒以预定配置路线抽吸和/或输注管，以在控制台上与抽吸和输注系统相配合。