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公开(公告)号：US20120241409A1
公开(公告)日：2012-09-27
申请号：US13412913
申请日：2012-03-06
CPC分类号： H01L51/003
摘要： In accordance with an embodiment, a pattern formation method includes: forming, on a first substrate, a fabrication target film having first and second regions; selectively applying, onto the first region a self-assembly material of a plurality of components that are phase-separable by a thermal treatment; baking the self-assembly material to phase-separate the self-assembly material into the components; removing any one of the components to form a first pattern; applying a curable resin onto the second region of the fabrication target film; bringing a dented second substrate corresponding to an arbitrary pattern closer to and into contact with the curable resin so that the second substrate faces the curable resin; curing the curable resin; detaching the second substrate from the curable resin to form a second pattern in the curable resin; and using the first and the second patterns as masks to fabricate the fabrication target film.
摘要翻译： 根据实施例，图案形成方法包括：在第一基板上形成具有第一和第二区域的制造靶膜; 在所述第一区域上选择性地将通过热处理可相分离的多个部件的自组装材料施加; 烘烤自组装材料以将自组装材料相分离成部件; 去除任何一个部件以形成第一图案; 将可固化树脂施加到制造目标膜的第二区域上; 使与第二基板相对应的任意图案的凹陷的第二基板与可固化树脂接近并与其接触，使得第二基板面向可固化树脂; 固化可固化树脂; 将第二基板从可固化树脂分离以在可固化树脂中形成第二图案; 并且使用第一和第二图案作为掩模来制造制造目标膜。
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公开(公告)号：US20110195189A1
公开(公告)日：2011-08-11
申请号：US12974946
申请日：2010-12-21
申请人： Yoshihisa KAWAMURA
发明人： Yoshihisa KAWAMURA
IPC分类号： B05D1/32
CPC分类号： G03F7/0002 , B82Y10/00 , B82Y40/00 , G03F7/2016 , H01L21/0337 , H01L21/76817
摘要： According to one embodiment, a pattern formation method is disclosed. The method includes applying an imprint material onto a workpiece film; and bringing a transfer surface having a first unevenness of a template into contact with the imprint material to form a second unevenness in the imprint material. The second unevenness reflects a configuration of the first unevenness. The method includes curing the imprint material; filling a mask material into a recess of the second unevenness of the cured imprint material; exposing a part of the workpiece film by using the filled mask material as a mask to pattern the imprint material; and patterning the workpiece film by using the patterned imprint material as a mask. A thickness of the imprint material between the workpiece film and a bottom face of the recess of the second unevenness is not less than 2.5 times a half pitch of the second unevenness.
摘要翻译： 根据一个实施例，公开了图案形成方法。 该方法包括将压印材料施加到工件膜上; 并且使具有模板的第一不均匀的转印表面与压印材料接触以在压印材料中形成第二不均匀性。 第二不均匀性反映第一不均匀的结构。 该方法包括固化印记材料; 将掩模材料填充到固化的压印材料的第二凹凸的凹部中; 通过使用填充的掩模材料作为掩模使一部分工件膜曝光以对压印材料进行图案化; 并通过使用图案化的印记材料作为掩模来对工件膜进行图案化。 工件薄膜与第二凹凸凹部的底面之间的压印材料的厚度不小于第二凹凸的半间距的2.5倍。
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公开(公告)号：US20100102000A1
公开(公告)日：2010-04-29
申请号：US12561768
申请日：2009-09-17
申请人： Yoshihisa KAWAMURA , Hisako Aoyama , Daizo Mutoh
发明人： Yoshihisa KAWAMURA , Hisako Aoyama , Daizo Mutoh
IPC分类号： B01D15/00
CPC分类号： G01N1/4077 , G01N2001/4088
摘要： A method for filtering a chemical in which a first chemical stored in a first tank is filtered by a filter and a second chemical obtained by the filtering is stored in a second tank has: adding the capture amounts corresponding to the individual first chemicals first to n-th stored in the first tank, and getting an added capture amount; and comparing the added capture amount and a predetermined limit capture amount of the filter, and exchanging the filter based on the comparison result.
摘要翻译： 一种用于过滤化学品的方法，其中通过过滤器过滤存储在第一罐中的第一化学品的化学品和通过过滤获得的第二化学品储存在第二罐中的方法：将对应于各个第一化学品的捕获量首先添加到n 储存在第一个储罐中，并获得额外的捕获量; 以及比较所添加的捕获量和所述滤波器的预定极限捕获量，以及基于所述比较结果交换所述滤波器。
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公开(公告)号：US07659060B2
公开(公告)日：2010-02-09
申请号：US10653586
申请日：2003-09-02
CPC分类号： C12Q1/6827 , C12Q2565/101 , C12Q2563/173
摘要： A method for identifying a nucleotide polymorphism, the method comprising hybridizing a labeled oligonucleotide for a wild type or a mutant type to a nucleic acid containing a specific nucleotide polymorphic site in a sample; allowing a nucleic acid-specific label to act thereon; detecting an interaction between the label of the oligonucleotide and the nucleic acid-specific label; and identifying a nucleotide polymorphism, wherein the identification utilizes a difference due to the nucleotide polymorphism in conditions under which the hybridized oligonucleotide is separated into a single strand.
摘要翻译： 一种用于鉴定核苷酸多态性的方法，所述方法包括将野生型或突变型的标记寡核苷酸与含有样品中特定核苷酸多态性位点的核酸杂交; 允许核酸特异性标记作用于其上; 检测寡核苷酸的标记与核酸特异性标记之间的相互作用; 并鉴定核苷酸多态性，其中鉴定在杂交寡核苷酸被分离成单链的条件下利用由于核苷酸多态性引起的差异。
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公开(公告)号：US20060179642A1
公开(公告)日：2006-08-17
申请号：US11337484
申请日：2006-01-24
申请人： Yoshihisa Kawamura
发明人： Yoshihisa Kawamura
CPC分类号： H03H9/173 , H03H3/02 , H03H9/02149 , H03H2003/021 , Y10T29/49005 , Y10T29/4908
摘要： A method for manufacturing a film bulk acoustic resonator includes forming a closed room in a supporting substrate; forming a bottom electrode above the closed room, the bottom electrode provided on a surface of the supporting substrate; forming a piezoelectric film on a surface of the bottom electrode; forming a top electrode facing the bottom electrode to sandwich the piezoelectric film; forming an opening connected to the closed room from the surface of the supporting substrate; and forming a cavity by removing a portion of the supporting substrate under the bottom electrode through the opening and the closed room.
摘要翻译： 一种膜体声波谐振器的制造方法，其特征在于，在支撑基板上形成封闭室， 在所述封闭室的上方形成底部电极，所述底部电极设置在所述支撑基板的表面上; 在所述底部电极的表面上形成压电膜; 形成面向底部电极的顶部电极以夹持压电膜; 从所述支撑基板的表面形成连接到所述封闭室的开口; 以及通过从所述开口和所述封闭室移除所述底部电极下方的所述支撑基板的一部分来形成空腔。
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公开(公告)号：US06884416B2
公开(公告)日：2005-04-26
申请号：US09781703
申请日：2001-02-12
CPC分类号： C12N9/0006 , C12N9/96 , C12Y101/05002
摘要： The present invention provides a stable lyophilized PQQ-dependent glucose dehydrogenase composition comprising a PQQ-dependent glucose dehydrogenase together with (i) at least one compound selected from the group consisting of aspartic acid, glutamic acid, α-ketoglutaric acid, malic acid, α-ketogluconic acid, α-cyclodextrin and their salts and (ii) an albumin.
摘要翻译： 本发明提供一种稳定的冻干的PQQ依赖性葡萄糖脱氢酶组合物，其包含PQQ依赖性葡萄糖脱氢酶以及（i）至少一种选自天冬氨酸，谷氨酸，α-酮戊二酸，苹果酸，α - 酮葡萄糖酸，α-环糊精及其盐和（ii）白蛋白。
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公开(公告)号：US06607662B1
公开(公告)日：2003-08-19
申请号：US09655070
申请日：2000-09-05
IPC分类号： B01L302
CPC分类号： G01N35/0098 , C12N15/1013 , C12Q1/6806 , G01N1/34 , G01N35/028 , C12Q2563/143
摘要： The present invention provides an apparatus for purifying nucleic acids such as DNA and RNA or proteins such as enzymes and antibodies from microorganisms such as viruses and bacteria or animal and plant tissues, the apparatus being capable of fast processing of a plurality of samples. More specifically, the present invention provides an apparatus for purifying nucleic acids or proteins using magnetically attractable particles, the apparatus comprising a plurality of piston pumps; a plurality of nozzles capable of having a plurality of disposable tips which are automatically attachable/detachable; and a mechanism which is capable of dispensing a desired amount of a reagent to be used subsequently in the next step into the same number of sections as that of the samples with high accuracy and at a high rate, while a mixture of a sample and a reagent are being mixed (stirred) by the pumps and nozzles, the apparatus being capable of rapidly processing a plurality of samples, wherein a series of steps from mixing (stirring) of the magnetically attractable particles and concentration of the sample to purification is automated with reduced wastes.
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公开(公告)号：US06420129B1
公开(公告)日：2002-07-16
申请号：US09424809
申请日：1999-11-29
IPC分类号： C12Q140
CPC分类号： G01N33/84 , C12Q1/40 , C12Q2334/00 , C12Q2334/10 , G01N31/22 , G01N2400/18 , G01N2800/04
摘要： There is provided a reagent composition for the enzymatic determination of electrolytes, which has high solution stability enabling it to stand up to its distribution in the market as a liquid reagent, and which further has excellent quantitative reliability and accuracy. This is a reagent composition for the determination of electrolytes such as calcium or chloride ions, which contains: (a) inactive &agr;-amylase; (b) a chelating agent; (c) a substrate for &agr;-amylase; and (d) a cyclodextrin derivative, and which may optionally further contain an SH group containing compound or a salt thereof.
摘要翻译： 提供了一种用于电解质酶测定的试剂组合物，其具有高的溶液稳定性，使其能够在液体试剂中作为其在市场上的分布，并且还具有优异的定量可靠性和精度。 这是用于测定电解质如钙或氯离子的试剂组合物，其包含：（a）无活性α-淀粉酶; （b）螯合剂; （c）α-淀粉酶底物; 和（d）环糊精衍生物，并且其可以任选地还含有含SH基团的化合物或其盐。
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69.发明授权公开(公告)号：US06303306B1
公开(公告)日：2001-10-16
申请号：US09292435
申请日：1999-04-15
IPC分类号： C12Q168
CPC分类号： C12Q1/6865 , C12Q2527/101
摘要： In a method for amplifying the specific nucleic acid sequence, a highly specific amplification which has low possibility of non-specific hybridization can be carried out. Highly stable reagents, the activities of which do not decrease in case of supply and storage, are also provided. Thermostable enzymes are used as RNA dependent DNA polymerase, DNA dependent DNA polymerase, DNA dependent RNA polymerase and ribonuclease H, which are required for the amplification system based on replicated RNA. Especially, it is preferable that a thermostable enzyme derived from Thermus thermophilus which has RNA dependent DNA polymerase activity, DNA dependent DNA polymerase activity and ribonuclease H activity, and thermostable DNA dependent RNA polymerase are used together. By this method, inactivation of enzymes are prevented by using thermostable enzymes, and the amplification can be carried out without sequential addition of enzymes.
摘要翻译： 在扩增特异性核酸序列的方法中，可以进行非特异性杂交的可能性低的高度特异性扩增。 还提供了稳定的试剂，其供应和储存的活性不降低。 热稳定酶用作基于复制RNA的扩增系统所需的RNA依赖性DNA聚合酶，DNA依赖性DNA聚合酶，DNA依赖性RNA聚合酶和核糖核酸酶H。 特别优选共同使用具有RNA依赖性DNA聚合酶活性，DNA依赖性DNA聚合酶活性和核糖核酸酶H活性的嗜热栖热菌的热稳定性酶和耐热性DNA依赖型RNA聚合酶。 通过这种方法，通过使用热稳定酶来防止酶的失活，并且可以不依次加入酶进行扩增。
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公开(公告)号：US5982176A
公开(公告)日：1999-11-09
申请号：US411939
申请日：1995-03-28
申请人： Yoshihisa Kawamura , Kazuo Kurihara , Zenkichi Nakamura , Kietsu Iwabuchi , Toshio Aizawa , Hideo Suyama
发明人： Yoshihisa Kawamura , Kazuo Kurihara , Zenkichi Nakamura , Kietsu Iwabuchi , Toshio Aizawa , Hideo Suyama
CPC分类号： G01R33/09 , G01C17/30 , H01J2229/0038
摘要： A geomagnetic direction sensor has a plurality of magnetic cores for converging terrestrial magnetism arranged circumferentially with pre-set gaps, and magneto-resistive effect devices in the gaps so as to lie substantially at right angles to the direction of the magnetic field in the gaps. The geomagnetic direction sensor has at least a pair of magneto-resistive effect devices lying substantially at right angles to each other. The magnetic core is formed of a magnetic material having soft magnetic properties. The current is supplied to the excitation coils placed around the magnetic core for applying a bias magnetic field to the magneto-resistive effect devices. Another set of magneto-resistive effect devices are connected in series with the magneto-resistive effect devices arranged within the gap so as to be substantially parallel to the direction of the magnetic field.
摘要翻译： 地磁方向传感器具有多个磁芯，用于会聚具有预先设定的间隙的周向布置的地磁，以及间隙中的磁阻效应器件，其基本上与间隙中的磁场方向成直角。 地磁方向传感器具有至少一对基本上彼此成直角的磁阻效应装置。 磁芯由具有软磁特性的磁性材料形成。 电流被提供给放置在磁芯周围的激励线圈，用于向磁阻效应器件施加偏置磁场。 另一组磁阻效应器件与布置在间隙内的磁阻效应器件串联连接，以便基本上平行于磁场的方向。
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